Madcam1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Madcam1
Entrez Gene ID	17123
Full Name	mucosal vascular addressin cell adhesion molecule 1
Synonyms	AV211525,MAdCAM-1
General protein information	Preferred Names mucosal vascular addressin cell adhesion molecule 1 Names mucosal addressin cell adhesion molecule 1 cell adhesion molecule 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10 C1\|10 39.72 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006513293.3	XP_006513356.1	mucosal addressin cell adhesion molecule 1 isoform X1
NM_013591.2	NP_038619.2	mucosal addressin cell adhesion molecule 1 precursor
NM_013591.3	NP_038619.2	mucosal addressin cell adhesion molecule 1 isoform 1 precursor
NM_001358785.1	NP_001345714.1	mucosal addressin cell adhesion molecule 1 isoform 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MADCAM1	NP_001019810.1
Mus musculus (house mouse)	Madcam1	NP_038619.2
Bos taurus (cattle)	MADCAM1	NP_001032910.1
Gallus gallus (chicken)	MADCAM1	XP_003642914.1
Rattus norvegicus (Norway rat)	Madcam1	NP_062190.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis.
Low S, Hirakawa J, Hoshino H, Uchimura K, Kawashima H, Kobayashi M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society22155417753363(2018 Jan)

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.
Onder L, M?rbe U, Pikor N, Novkovic M, Cheng HW, Hehlgans T, Pfeffer K, Becher B, Waisman A, R?licke T, Gommerman J, Mueller CG, Sawa S, Scandella E, Ludewig B
Immunity47(1)80-92.e4(2017 07)

?
Drescher HK, Schippers A, Clahsen T, Sahin H, Noels H, Hornef M, Wagner N, Trautwein C, Streetz KL, Kroy DC
Journal of hepatology66(6)1251-1264(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results uncovered a previously unknown role of integrin a4b7-MAdCAM-1 interactions as drivers of colitis by directing inflammatory monocytes into the colon.
Title: ?7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon.

beta7 integrin, when expressed by hematopoietic stem cells (HSC), interacted with its endothelial ligand MAdCAM-1 in the Bone marrow microenvironment, thereby promoting HSC homing and engraftment.
Title: Evidence that ?7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1.

Nkx2-3 deficiency reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.
Title: Absence of Nkx2-3 homeodomain transcription factor reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.

findings indicate that alpha4beta7*IgG can be used as a probe for functional MAdCAM-1 expressed on HEVs in GALT and could potentially serve as an anti-inflammatory drug inhibiting GALT-specific lymphocyte migration
Title: An integrin alpha4beta7?IgG heterodimeric chimera binds to MAdCAM-1 on high endothelial venules in gut-associated lymphoid tissue.

ectopic expression of MAdCAM-1 at the BBB does not increase alpha4beta7-integrin-mediated immune cell trafficking into the CNS during MOG(aa35-55)-induced experimental autoimmune encephalomyelitis
Title: TET inducible expression of the ?4?7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis.

The following Madcam1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Madcam1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu44253	NM_001358785.1 Latest version!	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu44253	XM_006513293.3 Latest version!	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu18746	NM_013591.3 Latest version!	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OMu18746	NM_013591.2	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Madcam1 ( NM_001358785.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001345714.1 Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu44253
Clone ID Related Accession (Same CDS sequence)	XM_006513293.3 , NM_001358785.1
Accession Version	NM_001358785.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	mucosal addressin cell adhesion molecule 1 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ066404.1, AK137028.1, BB797427.1 and BE691220.1. On Dec 9, 2017 this sequence version replaced XM_006513293.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024372.1, AK156096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGCCTCC 
ACCGTCGTCC TATGGATTGG CAGCTTGGTG CTGGGGCTGC TTGCACTGGT CTTCCTTGCC 
TACCGCCTGT GGAAATGCTA CCGGCCAGGT CCTCGCCCAG ACACTAGCTC ATGTACACAC 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345714.1
CDS	49..834
Translation	MESILALLLALALVPYQLSRGQSFQVNPPESEVAVAMGTSLQITCSMSCDEGVARVHWRGLDTSLGSVQTLPGSSILSVRGMLSDTGTPVCVGSCGSRSFQHSVKILVYAFPDQLVVSPEFLVPGQDQVVSCTAHNIWPADPNSLSFALLLGEQRLEGAQALEPEQEEEIQEAEGTPLFRMTQRWRLPSLGTPAPPALHCQVTMQLPKLVLTHRKEIPASTVVLWIGSLVLGLLALVFLAYRLWKCYRPGPRPDTSSCTHL

Target ORF information:

RefSeq Version	NM_001358785.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358785.1

ORF Insert Sequence:

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGCCTCC 
ACCGTCGTCC TATGGATTGG CAGCTTGGTG CTGGGGCTGC TTGCACTGGT CTTCCTTGCC 
TACCGCCTGT GGAAATGCTA CCGGCCAGGT CCTCGCCCAG ACACTAGCTC ATGTACACAC 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Madcam1 ( XM_006513293.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513356.1 Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44253
Clone ID Related Accession (Same CDS sequence)	XM_006513293.3 , NM_001358785.1
Accession Version	XM_006513293.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	mucosal addressin cell adhesion molecule 1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513293.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGCCTCC 
ACCGTCGTCC TATGGATTGG CAGCTTGGTG CTGGGGCTGC TTGCACTGGT CTTCCTTGCC 
TACCGCCTGT GGAAATGCTA CCGGCCAGGT CCTCGCCCAG ACACTAGCTC ATGTACACAC 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513356.1
CDS	214..999
Translation	MESILALLLALALVPYQLSRGQSFQVNPPESEVAVAMGTSLQITCSMSCDEGVARVHWRGLDTSLGSVQTLPGSSILSVRGMLSDTGTPVCVGSCGSRSFQHSVKILVYAFPDQLVVSPEFLVPGQDQVVSCTAHNIWPADPNSLSFALLLGEQRLEGAQALEPEQEEEIQEAEGTPLFRMTQRWRLPSLGTPAPPALHCQVTMQLPKLVLTHRKEIPASTVVLWIGSLVLGLLALVFLAYRLWKCYRPGPRPDTSSCTHL

Target ORF information:

RefSeq Version	XM_006513293.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513293.3

ORF Insert Sequence:

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGCCTCC 
ACCGTCGTCC TATGGATTGG CAGCTTGGTG CTGGGGCTGC TTGCACTGGT CTTCCTTGCC 
TACCGCCTGT GGAAATGCTA CCGGCCAGGT CCTCGCCCAG ACACTAGCTC ATGTACACAC 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Madcam1 ( NM_013591.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038619.2 Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), mRNA.

Price & Availability↑

CloneID	OMu18746
Clone ID Related Accession (Same CDS sequence)	NM_013591.2 , NM_013591.3
Accession Version	NM_013591.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-21
Organism	Mus musculus(House mouse)
Product	mucosal addressin cell adhesion molecule 1 precursor
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK137028.1 and BE632565.1. On Apr 19, 2007 this sequence version replaced NM_013591.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK137028.1, L21203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGTACTA 
CAGAGCCAGA CCTCACCTAA GCCCCCCAAC ACGACCTCTG CTGAGCCCTA CATCCTGACC 
TCATCAAGTA CTGCTGAGGC AGTCTCCACT GGGCTCAACA TCACCACCCT ACCTTCTGCC 
CCTCCATACC CCAAGCTTAG CCCTAGGACT CTGAGCTCTG AGGGACCTTG CCGCCCGAAA 
ATCCACCAGG ACCTGGAGGC AGGCTGGGAG CTACTCTGTG AAGCATCCTG TGGGCCCGGA 
GTTACTGTGC GCTGGACCTT GGCTCCTGGC GACCTGGCAA CCTACCACAA GAGGGAGGCT 
GGGGCCCAGG CATGGCTAAG CGTGCTGCCC CCAGGTCCCA TGGTAGAGGG CTGGTTCCAG 
TGCCGCCAGG ACCCTGGCGG GCAGGTGACC AATCTGTATG TTCCTGGCCA GGTGACCCCG 
AATTCCTCCT CCACCGTCGT CCTATGGATT GGCAGCTTGG TGCTGGGGCT GCTTGCACTG 
GTCTTCCTTG CCTACCGCCT GTGGAAATGC TACCGGCCAG GTCCTCGCCC AGACACTAGC 
TCATGTACAC ACCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038619.2
CDS	34..1251
Translation	MESILALLLALALVPYQLSRGQSFQVNPPESEVAVAMGTSLQITCSMSCDEGVARVHWRGLDTSLGSVQTLPGSSILSVRGMLSDTGTPVCVGSCGSRSFQHSVKILVYAFPDQLVVSPEFLVPGQDQVVSCTAHNIWPADPNSLSFALLLGEQRLEGAQALEPEQEEEIQEAEGTPLFRMTQRWRLPSLGTPAPPALHCQVTMQLPKLVLTHRKEIPVLQSQTSPKPPNTTSAEPYILTSSSTAEAVSTGLNITTLPSAPPYPKLSPRTLSSEGPCRPKIHQDLEAGWELLCEASCGPGVTVRWTLAPGDLATYHKREAGAQAWLSVLPPGPMVEGWFQCRQDPGGQVTNLYVPGQVTPNSSSTVVLWIGSLVLGLLALVFLAYRLWKCYRPGPRPDTSSCTHL

Target ORF information:

RefSeq Version	NM_013591.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013591.2

ORF Insert Sequence:

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGTACTA 
CAGAGCCAGA CCTCACCTAA GCCCCCCAAC ACGACCTCTG CTGAGCCCTA CATCCTGACC 
TCATCAAGTA CTGCTGAGGC AGTCTCCACT GGGCTCAACA TCACCACCCT ACCTTCTGCC 
CCTCCATACC CCAAGCTTAG CCCTAGGACT CTGAGCTCTG AGGGACCTTG CCGCCCGAAA 
ATCCACCAGG ACCTGGAGGC AGGCTGGGAG CTACTCTGTG AAGCATCCTG TGGGCCCGGA 
GTTACTGTGC GCTGGACCTT GGCTCCTGGC GACCTGGCAA CCTACCACAA GAGGGAGGCT 
GGGGCCCAGG CATGGCTAAG CGTGCTGCCC CCAGGTCCCA TGGTAGAGGG CTGGTTCCAG 
TGCCGCCAGG ACCCTGGCGG GCAGGTGACC AATCTGTATG TTCCTGGCCA GGTGACCCCG 
AATTCCTCCT CCACCGTCGT CCTATGGATT GGCAGCTTGG TGCTGGGGCT GCTTGCACTG 
GTCTTCCTTG CCTACCGCCT GTGGAAATGC TACCGGCCAG GTCCTCGCCC AGACACTAGC 
TCATGTACAC ACCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Madcam1 ( NM_013591.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038619.2 Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18746
Clone ID Related Accession (Same CDS sequence)	NM_013591.2 , NM_013591.3
Accession Version	NM_013591.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	mucosal addressin cell adhesion molecule 1 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ066404.1, AK137028.1, BE632565.1 and BE691220.1. On Dec 9, 2017 this sequence version replaced NM_013591.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK137028.1, L21203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGTACTA 
CAGAGCCAGA CCTCACCTAA GCCCCCCAAC ACGACCTCTG CTGAGCCCTA CATCCTGACC 
TCATCAAGTA CTGCTGAGGC AGTCTCCACT GGGCTCAACA TCACCACCCT ACCTTCTGCC 
CCTCCATACC CCAAGCTTAG CCCTAGGACT CTGAGCTCTG AGGGACCTTG CCGCCCGAAA 
ATCCACCAGG ACCTGGAGGC AGGCTGGGAG CTACTCTGTG AAGCATCCTG TGGGCCCGGA 
GTTACTGTGC GCTGGACCTT GGCTCCTGGC GACCTGGCAA CCTACCACAA GAGGGAGGCT 
GGGGCCCAGG CATGGCTAAG CGTGCTGCCC CCAGGTCCCA TGGTAGAGGG CTGGTTCCAG 
TGCCGCCAGG ACCCTGGCGG GCAGGTGACC AATCTGTATG TTCCTGGCCA GGTGACCCCG 
AATTCCTCCT CCACCGTCGT CCTATGGATT GGCAGCTTGG TGCTGGGGCT GCTTGCACTG 
GTCTTCCTTG CCTACCGCCT GTGGAAATGC TACCGGCCAG GTCCTCGCCC AGACACTAGC 
TCATGTACAC ACCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038619.2
CDS	49..1266
Translation	MESILALLLALALVPYQLSRGQSFQVNPPESEVAVAMGTSLQITCSMSCDEGVARVHWRGLDTSLGSVQTLPGSSILSVRGMLSDTGTPVCVGSCGSRSFQHSVKILVYAFPDQLVVSPEFLVPGQDQVVSCTAHNIWPADPNSLSFALLLGEQRLEGAQALEPEQEEEIQEAEGTPLFRMTQRWRLPSLGTPAPPALHCQVTMQLPKLVLTHRKEIPVLQSQTSPKPPNTTSAEPYILTSSSTAEAVSTGLNITTLPSAPPYPKLSPRTLSSEGPCRPKIHQDLEAGWELLCEASCGPGVTVRWTLAPGDLATYHKREAGAQAWLSVLPPGPMVEGWFQCRQDPGGQVTNLYVPGQVTPNSSSTVVLWIGSLVLGLLALVFLAYRLWKCYRPGPRPDTSSCTHL

Target ORF information:

RefSeq Version	NM_013591.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mucosal vascular addressin cell adhesion molecule 1 (Madcam1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013591.3

ORF Insert Sequence:

ATGGAATCCA TCCTGGCCCT CCTGCTGGCC CTGGCCCTAG TACCCTACCA GCTCAGCAGA 
GGACAGTCCT TCCAGGTGAA CCCCCCTGAG TCTGAGGTAG CTGTGGCCAT GGGCACATCC 
CTCCAGATCA CCTGCAGCAT GTCCTGTGAC GAGGGTGTAG CCCGGGTGCA CTGGCGTGGT 
CTGGACACCA GCTTGGGCAG TGTACAGACC CTCCCAGGCA GCAGTATCCT CTCTGTACGG 
GGCATGCTGT CAGACACAGG CACTCCTGTG TGTGTGGGCT CCTGCGGGAG TCGAAGCTTC 
CAGCACTCCG TGAAGATCCT TGTGTATGCC TTCCCAGACC AGCTGGTGGT GTCCCCGGAG 
TTCCTTGTAC CTGGACAGGA CCAGGTGGTG TCCTGCACGG CCCACAACAT CTGGCCTGCA 
GACCCGAACA GTCTCTCCTT TGCCCTGCTA CTGGGAGAGC AGAGACTGGA GGGTGCCCAA 
GCCCTGGAAC CAGAGCAAGA AGAGGAGATA CAAGAGGCTG AGGGCACACC ACTGTTCCGA 
ATGACACAAC GCTGGCGGTT ACCCTCCCTG GGGACCCCTG CCCCTCCTGC CCTTCACTGC 
CAGGTCACCA TGCAGCTGCC CAAACTGGTG CTGACCCATA GAAAGGAGAT TCCAGTACTA 
CAGAGCCAGA CCTCACCTAA GCCCCCCAAC ACGACCTCTG CTGAGCCCTA CATCCTGACC 
TCATCAAGTA CTGCTGAGGC AGTCTCCACT GGGCTCAACA TCACCACCCT ACCTTCTGCC 
CCTCCATACC CCAAGCTTAG CCCTAGGACT CTGAGCTCTG AGGGACCTTG CCGCCCGAAA 
ATCCACCAGG ACCTGGAGGC AGGCTGGGAG CTACTCTGTG AAGCATCCTG TGGGCCCGGA 
GTTACTGTGC GCTGGACCTT GGCTCCTGGC GACCTGGCAA CCTACCACAA GAGGGAGGCT 
GGGGCCCAGG CATGGCTAAG CGTGCTGCCC CCAGGTCCCA TGGTAGAGGG CTGGTTCCAG 
TGCCGCCAGG ACCCTGGCGG GCAGGTGACC AATCTGTATG TTCCTGGCCA GGTGACCCCG 
AATTCCTCCT CCACCGTCGT CCTATGGATT GGCAGCTTGG TGCTGGGGCT GCTTGCACTG 
GTCTTCCTTG CCTACCGCCT GTGGAAATGC TACCGGCCAG GTCCTCGCCC AGACACTAGC 
TCATGTACAC ACCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society22155417753363(2018 Jan)
Low S,Hirakawa J,Hoshino H,Uchimura K,Kawashima H,Kobayashi M

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.
Immunity47(1)80-92.e4(2017 07)
Onder L,M?rbe U,Pikor N,Novkovic M,Cheng HW,Hehlgans T,Pfeffer K,Becher B,Waisman A,R?licke T,Gommerman J,Mueller CG,Sawa S,Scandella E,Ludewig B

?
Journal of hepatology66(6)1251-1264(2017 Jun)
Drescher HK,Schippers A,Clahsen T,Sahin H,Noels H,Hornef M,Wagner N,Trautwein C,Streetz KL,Kroy DC

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Madcam1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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