Ly6d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ly6d
Entrez Gene ID	17068
Full Name	lymphocyte antigen 6 complex, locus D
Synonyms	Ly-61,Ly61,Thb
General protein information	Preferred Names lymphocyte antigen 6 complex, locus D Names lymphocyte antigen 6D ly-6D thymocyte B-cell antigen
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 D3\|15 34.27 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010742.1	NP_034872.1	lymphocyte antigen 6D precursor

Pathways from BioSystems

Homologies

	LY6D	XP_001083864.1
Mus musculus (house mouse)	Ly6d	NP_034872.1
Canis lupus familiaris (dog)	LOC609112	XP_851409.2
Pan troglodytes (chimpanzee)	LY6D	XP_001150525.2
Rattus norvegicus (Norway rat)	Ly6d	NP_001124024.1
Bos taurus (cattle)	LY6D	NP_001069985.1
Homo sapiens (human)	LY6D	NP_003686.1

Gene Ontology
Bibliography

Related articles in PubMed

Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
Luo X, Liao R, Hanley KL, Zhu HH, Malo KN, Hernandez C, Wei X, Varki NM, Alderson N, Chu C, Li S, Fan J, Loomba R, Qiu SJ, Feng GS
Cell reports17(11)2979-2993(2016 12)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Loughner CL, Bruford EA, McAndrews MS, Delp EE, Swamynathan S, Swamynathan SK
Human genomics1010(2016 Apr)

RAG-1 and Ly6D independently reflect progression in the B lymphoid lineage.
Zhang Q, Esplin BL, Iida R, Garrett KP, Huang ZL, Medina KL, Kincade PW
PloS one8(8)e72397(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of RAG-1 and display of Ly6D are both milestone events, but they are neither synchronized nor dependent on each other.
Title: RAG-1 and Ly6D independently reflect progression in the B lymphoid lineage.

identified Ly6d, which divides CLPs into two distinct populations: one that retains full in vivo lymphoid potential and produces more thymocytes at early timepoints than LMPP, and another that behaves essentially as a B-cell progenitor
Title: Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.

Data show that ten genes (Fsp27, Aqp4, Cd36, Ly6d, Scd1, Hsd3b5, Syt1, Cyp7b1, and Tff3) showed significant associations among their expressions and the degree of hepatic steatosis.
Title: Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver.

The following Ly6d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ly6d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18129	NM_010742.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus D (Ly6d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ly6d ( NM_010742.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034872.1 Mus musculus lymphocyte antigen 6 complex, locus D (Ly6d), mRNA.

Price & Availability↑

CloneID	OMu18129
Clone ID Related Accession (Same CDS sequence)	NM_010742.1
Accession Version	NM_010742.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6D precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X63782.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X63782.1, CB587815.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGAAGACAG CTCTGCTCGT CCTCCTTGTC TTGGCTGTGG CCACTAGCCC AGCCTGGGCA 
CTTCGATGTC ACGTGTGCAC CAACAGTGCC AACTGTAAGA ACCCTCAGGT CTGCCCGTCC 
AACTTCTACT TCTGCAAAAC CGTCACCTCA GTGGAGCCTC TGAATGGGAA CCTGGTGAGG 
AAAGAGTGTG CAAACTCATG CACCTCCGAC TACAGCCAGC AGGGCCATGT CAGCAGTGGT 
TCCGAGGTCA CACAATGCTG CCAGACTGAC CTATGCAACG AGAGGCTGGT CAGCGCTGCA 
CCTGGACATG CCCTGCTCAG CAGTGTCACC CTGGGCCTGG CAACGAGCCT CAGCCTGCTC 
ACTGTTATGG CTCTCTGCCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034872.1
CDS	8..391
Translation	MKTALLVLLVLAVATSPAWALRCHVCTNSANCKNPQVCPSNFYFCKTVTSVEPLNGNLVRKECANSCTSDYSQQGHVSSGSEVTQCCQTDLCNERLVSAAPGHALLSSVTLGLATSLSLLTVMALCL

Target ORF information:

RefSeq Version	NM_010742.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus D (Ly6d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010742.1

ORF Insert Sequence:

ATGAAGACAG CTCTGCTCGT CCTCCTTGTC TTGGCTGTGG CCACTAGCCC AGCCTGGGCA 
CTTCGATGTC ACGTGTGCAC CAACAGTGCC AACTGTAAGA ACCCTCAGGT CTGCCCGTCC 
AACTTCTACT TCTGCAAAAC CGTCACCTCA GTGGAGCCTC TGAATGGGAA CCTGGTGAGG 
AAAGAGTGTG CAAACTCATG CACCTCCGAC TACAGCCAGC AGGGCCATGT CAGCAGTGGT 
TCCGAGGTCA CACAATGCTG CCAGACTGAC CTATGCAACG AGAGGCTGGT CAGCGCTGCA 
CCTGGACATG CCCTGCTCAG CAGTGTCACC CTGGGCCTGG CAACGAGCCT CAGCCTGCTC 
ACTGTTATGG CTCTCTGCCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
Cell reports17(11)2979-2993(2016 12)
Luo X,Liao R,Hanley KL,Zhu HH,Malo KN,Hernandez C,Wei X,Varki NM,Alderson N,Chu C,Li S,Fan J,Loomba R,Qiu SJ,Feng GS

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Human genomics1010(2016 Apr)
Loughner CL,Bruford EA,McAndrews MS,Delp EE,Swamynathan S,Swamynathan SK

RAG-1 and Ly6D independently reflect progression in the B lymphoid lineage.
PloS one8(8)e72397(2013)
Zhang Q,Esplin BL,Iida R,Garrett KP,Huang ZL,Medina KL,Kincade PW

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Ly6d cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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