Lrrn1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrn1
Entrez Gene ID	16979
Full Name	leucine rich repeat protein 1, neuronal
Synonyms	2810047E21Rik,NLRR-1
General protein information	Preferred Names leucine rich repeat protein 1, neuronal Names leucine-rich repeat neuronal protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_008516.4	NP_032542.1	leucine-rich repeat neuronal protein 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LRRN1	NP_001074207.1
Homo sapiens (human)	LRRN1	NP_065924.3
Pan troglodytes (chimpanzee)	LRRN1	XP_526119.2
Rattus norvegicus (Norway rat)	Lrrn1	NP_001032440.1
Gallus gallus (chicken)	LRRN1	NP_001091008.1
Xenopus tropicalis (tropical clawed frog)	LOC100492182	XP_002938357.1
Danio rerio (zebrafish)	lrrn1	NP_001124166.1
	LRRN1	XP_001099632.1
Canis lupus familiaris (dog)	LRRN1	XP_003432798.1
Mus musculus (house mouse)	Lrrn1	NP_032542.1

Gene Ontology
Bibliography

Related articles in PubMed

Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.
Satoh S, Takatori A, Ogura A, Kohashi K, Souzaki R, Kinoshita Y, Taguchi T, Hossain MS, Ohira M, Nakamura Y, Nakagawara A
Scientific reports632682(2016 Sep)

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y
PloS one10(3)e0121550(2015)

Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Kong P, Racedo SE, Macchiarulo S, Hu Z, Carpenter C, Guo T, Wang T, Zheng D, Morrow BE
Human molecular genetics23(16)4215-31(2014 Aug)

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Um JW, Pramanik G, Ko JS, Song MY, Lee D, Kim H, Park KS, S?dhof TC, Tabuchi K, Ko J
Cell reports6(6)1096-1109(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NLRR-1 is expressed in a subset of myotome cells.
Title: The NLRR gene family and mouse development: Modified differential display PCR identifies NLRR-1 as a gene expressed in early somitic myoblasts.

The following Lrrn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu17649	NM_008516.4 Latest version!	Mus musculus leucine rich repeat protein 1, neuronal (Lrrn1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$419.30 $599.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrn1 ( NM_008516.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032542.1 Mus musculus leucine rich repeat protein 1, neuronal (Lrrn1), mRNA.

Price & Availability↑

CloneID	OMu17649
Clone ID Related Accession (Same CDS sequence)	NM_008516.4
Accession Version	NM_008516.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2151bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat neuronal protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK139965.1, AK160841.1 and AC155327.3. On Apr 7, 2011 this sequence version replaced NM_008516.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK139965.1, AK139355.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGAT TGAGCACTGG GAAAGCAGCT TGCCAGGTGG TGCTGGGCTT GCTGATAACT 
TCATTAACTG AATCTTCCAT ACTGACTAGT GAGTGTCCCC AGCTTTGTGT TTGTGAAATT 
CGTCCTTGGT TTACCCCACA GTCCACCTAC AGAGAAGCCA CCACCGTGGA TTGTAATGAC 
CTCCGCCTAA CCAGGATCCC TGGCAACCTC TCTAGTGACA CACAAGTGCT TCTCTTACAG 
AGCAATAACA TCGCCAAGAC CGTGGACGAG CTGCAGCAGC TCTTCAACTT GACCGAGCTG 
GATTTCTCCC AGAACAACTT TACAAACATC AAAGAGGTAG GGCTGGCAAA CTTGACCCAG 
CTCACAACCC TGCATCTAGA GGAAAATCAG ATTTCAGAGA TGACGGATTA CTGTCTGCAA 
GACCTCAGCA ACCTTCAAGA ACTCTACATC AACCACAACC AGATCAGCAC AATCTCTGCC 
AACGCCTTTT CTGGCTTGAA AAATCTCTTG AGGCTGCACC TGAATTCCAA TAAGTTGAAA 
GTGATCGATA GCCGCTGGTT TGATTCCACT CCCAACCTGG AAATTCTCAT GATTGGGGAA 
AACCCTGTGA TTGGAATCCT GGACATGAAC TTCAGACCTC TCTCCAACCT GAGAAGCCTA 
GTGTTAGCAG GAATGTACCT CACTGATGTT CCCGGAAACG CCTTGGTAGG CTTGGATAGC 
CTCGAGAGCC TGTCTTTCTA TGACAACAAA CTGATCAAAG TCCCTCAACT TGCCCTGCAA 
AAAGTTCCAA ATTTGAAATT TTTAGACCTC AATAAAAATC CTATTCACAA AATCCAAGAA 
GGAGACTTTA AAAATATGCT TCGGTTAAAA GAACTGGGAA TCAACAACAT GGGAGAGCTG 
GTTTCCGTGG ACCGCTATGC CCTGGATAAC TTGCCAGAAT TGACAAAGCT CGAAGCAACC 
AATAACCCCA AACTGTCATA CATCCACCGT TTGGCTTTCC GTAGTGTGCC GGCTCTAGAA 
AGCTTAATGT TGAACAACAA TGCCTTGAAT GCCGTGTACC AAAAAACAGT GGAATCTCTT 
CCCAATCTGC GTGAGATCAG CATCCACAGC AACCCGCTGA GGTGTGACTG TGTCATCCAC 
TGGATCAACT CCAACAAAAC CAACATTCGC TTCATGGAGC CCCTCTCCAT GTTCTGTGCC 
ATGCCACCGG AATACAGGGG GCAGCAGGTG AAGGAGGTCC TAATCCAGGA CTCAAGTGAG 
CAGTGCCTCC CGATGATATC GCACGATACA TTCCCTAATC ATCTAAACAT GGACATTGGT 
ACAACACTTT TCCTAGACTG TCGGGCCATG GCTGAGCCAG AACCAGAGAT TTACTGGGTC 
ACTCCCATTG GAAATAAGAT AACCGTGGAA ACTCTTTCAG ACAAATACAA GCTGAGTAGT 
GAGGGCACCT TGGAGATAGC AAACATACAG ATTGAAGACT CAGGAAGGTA CACCTGCGTT 
GCCCAGAATG TCCAAGGAGC AGACACTCGA GTGGCAACTA TCAAGGTTAA TGGAACCCTT 
CTAGATGGTG CACAGGTGCT GAAAATATAT GTCAAACAGA CAGAATCTCA TTCGATTTTA 
GTATCTTGGA AAGTTAATTC CAATGTCATG ACATCGAACT TGAAATGGTC ATCTGCCACT 
ATGAAGATCG ACAACCCCCA CATAACATAC ACAGCCAGGG TGCCAGTAGA TGTTCATGAA 
TATAACCTAA CACATCTGCA GCCTTCTACG GATTATGAAG TGTGTCTCAC GGTGTCCAAC 
ATCCATCAGC AGACTCAGAA GTCATGTGTC AATGTCACAA CCAAAACCGC TGCCTTCGCC 
CTGGACATCT CTGACCATGA AACCAGCACC GCCCTTGCTG CGGTGATGGG GTCCATGTTT 
GCCGTCATCA GTCTAGCATC CATCGCTATT TACATCGCGA AAAGGTTTAA GAGGAAAAAT 
TACCACCATT CGCTGAAAAA GTATATGCAA AAAACCTCGT CCATCCCACT GAACGAGCTG 
TACCCCCCAC TCATTAACCT CTGGGAAGCT GACAGTGACA AGGACAAAGA TGGCTCGGCA 
GACACCAAGC CAACCCAGGT TGACACATCC AGAAGCTATT ACATGTGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032542.1
CDS	771..2921
Translation	MARLSTGKAACQVVLGLLITSLTESSILTSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPGNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISTISANAFSGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFRPLSNLRSLVLAGMYLTDVPGNALVGLDSLESLSFYDNKLIKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAVYQKTVESLPNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYRGQQVKEVLIQDSSEQCLPMISHDTFPNHLNMDIGTTLFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEIANIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGAQVLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVNVTTKTAAFALDISDHETSTALAAVMGSMFAVISLASIAIYIAKRFKRKNYHHSLKKYMQKTSSIPLNELYPPLINLWEADSDKDKDGSADTKPTQVDTSRSYYMW

Target ORF information:

RefSeq Version	NM_008516.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat protein 1, neuronal (Lrrn1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008516.4

ORF Insert Sequence:

ATGGCCAGAT TGAGCACTGG GAAAGCAGCT TGCCAGGTGG TGCTGGGCTT GCTGATAACT 
TCATTAACTG AATCTTCCAT ACTGACTAGT GAGTGTCCCC AGCTTTGTGT TTGTGAAATT 
CGTCCTTGGT TTACCCCACA GTCCACCTAC AGAGAAGCCA CCACCGTGGA TTGTAATGAC 
CTCCGCCTAA CCAGGATCCC TGGCAACCTC TCTAGTGACA CACAAGTGCT TCTCTTACAG 
AGCAATAACA TCGCCAAGAC CGTGGACGAG CTGCAGCAGC TCTTCAACTT GACCGAGCTG 
GATTTCTCCC AGAACAACTT TACAAACATC AAAGAGGTAG GGCTGGCAAA CTTGACCCAG 
CTCACAACCC TGCATCTAGA GGAAAATCAG ATTTCAGAGA TGACGGATTA CTGTCTGCAA 
GACCTCAGCA ACCTTCAAGA ACTCTACATC AACCACAACC AGATCAGCAC AATCTCTGCC 
AACGCCTTTT CTGGCTTGAA AAATCTCTTG AGGCTGCACC TGAATTCCAA TAAGTTGAAA 
GTGATCGATA GCCGCTGGTT TGATTCCACT CCCAACCTGG AAATTCTCAT GATTGGGGAA 
AACCCTGTGA TTGGAATCCT GGACATGAAC TTCAGACCTC TCTCCAACCT GAGAAGCCTA 
GTGTTAGCAG GAATGTACCT CACTGATGTT CCCGGAAACG CCTTGGTAGG CTTGGATAGC 
CTCGAGAGCC TGTCTTTCTA TGACAACAAA CTGATCAAAG TCCCTCAACT TGCCCTGCAA 
AAAGTTCCAA ATTTGAAATT TTTAGACCTC AATAAAAATC CTATTCACAA AATCCAAGAA 
GGAGACTTTA AAAATATGCT TCGGTTAAAA GAACTGGGAA TCAACAACAT GGGAGAGCTG 
GTTTCCGTGG ACCGCTATGC CCTGGATAAC TTGCCAGAAT TGACAAAGCT CGAAGCAACC 
AATAACCCCA AACTGTCATA CATCCACCGT TTGGCTTTCC GTAGTGTGCC GGCTCTAGAA 
AGCTTAATGT TGAACAACAA TGCCTTGAAT GCCGTGTACC AAAAAACAGT GGAATCTCTT 
CCCAATCTGC GTGAGATCAG CATCCACAGC AACCCGCTGA GGTGTGACTG TGTCATCCAC 
TGGATCAACT CCAACAAAAC CAACATTCGC TTCATGGAGC CCCTCTCCAT GTTCTGTGCC 
ATGCCACCGG AATACAGGGG GCAGCAGGTG AAGGAGGTCC TAATCCAGGA CTCAAGTGAG 
CAGTGCCTCC CGATGATATC GCACGATACA TTCCCTAATC ATCTAAACAT GGACATTGGT 
ACAACACTTT TCCTAGACTG TCGGGCCATG GCTGAGCCAG AACCAGAGAT TTACTGGGTC 
ACTCCCATTG GAAATAAGAT AACCGTGGAA ACTCTTTCAG ACAAATACAA GCTGAGTAGT 
GAGGGCACCT TGGAGATAGC AAACATACAG ATTGAAGACT CAGGAAGGTA CACCTGCGTT 
GCCCAGAATG TCCAAGGAGC AGACACTCGA GTGGCAACTA TCAAGGTTAA TGGAACCCTT 
CTAGATGGTG CACAGGTGCT GAAAATATAT GTCAAACAGA CAGAATCTCA TTCGATTTTA 
GTATCTTGGA AAGTTAATTC CAATGTCATG ACATCGAACT TGAAATGGTC ATCTGCCACT 
ATGAAGATCG ACAACCCCCA CATAACATAC ACAGCCAGGG TGCCAGTAGA TGTTCATGAA 
TATAACCTAA CACATCTGCA GCCTTCTACG GATTATGAAG TGTGTCTCAC GGTGTCCAAC 
ATCCATCAGC AGACTCAGAA GTCATGTGTC AATGTCACAA CCAAAACCGC TGCCTTCGCC 
CTGGACATCT CTGACCATGA AACCAGCACC GCCCTTGCTG CGGTGATGGG GTCCATGTTT 
GCCGTCATCA GTCTAGCATC CATCGCTATT TACATCGCGA AAAGGTTTAA GAGGAAAAAT 
TACCACCATT CGCTGAAAAA GTATATGCAA AAAACCTCGT CCATCCCACT GAACGAGCTG 
TACCCCCCAC TCATTAACCT CTGGGAAGCT GACAGTGACA AGGACAAAGA TGGCTCGGCA 
GACACCAAGC CAACCCAGGT TGACACATCC AGAAGCTATT ACATGTGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.
Scientific reports632682(2016 Sep)
Satoh S,Takatori A,Ogura A,Kohashi K,Souzaki R,Kinoshita Y,Taguchi T,Hossain MS,Ohira M,Nakamura Y,Nakagawara A

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
PloS one10(3)e0121550(2015)
Gu Z,Imai F,Kim IJ,Fujita H,Katayama Ki,Mori K,Yoshihara Y,Yoshida Y

Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Human molecular genetics23(16)4215-31(2014 Aug)
Kong P,Racedo SE,Macchiarulo S,Hu Z,Carpenter C,Guo T,Wang T,Zheng D,Morrow BE

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Cell reports6(6)1096-1109(2014 Mar)
Um JW,Pramanik G,Ko JS,Song MY,Lee D,Kim H,Park KS,S?dhof TC,Tabuchi K,Ko J

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Lrrn1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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