Phyh cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Phyh
Entrez Gene ID	16922
Full Name	phytanoyl-CoA hydroxylase
Synonyms	AI256161,AI265699,Lnap1,PAHX
General protein information	Preferred Names phytanoyl-CoA hydroxylase Names phytanoyl-CoA dioxygenase, peroxisomal lupus nephritis-associated peptide 1 phytanic acid oxidase phytanoyl-CoA alpha-hydroxylase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_010726.2	NP_034856.1	phytanoyl-CoA dioxygenase, peroxisomal precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC100300115	XP_003586818.1
Bos taurus (cattle)	PHYH	NP_776567.1
Mus musculus (house mouse)	Phyh	NP_034856.1
Danio rerio (zebrafish)	phyh	NP_001017823.1
Canis lupus familiaris (dog)	LOC478000	NP_001240649.1
Caenorhabditis elegans (roundworm)	CELE_ZK550.6	NP_503062.1
Homo sapiens (human)	PHYH	NP_006205.1
Gallus gallus (chicken)	PHYH	XP_424238.3
Pan troglodytes (chimpanzee)	PHYH	XP_507662.3
Rattus norvegicus (Norway rat)	Phyh	NP_446126.1
Danio rerio (zebrafish)	LOC798210	XP_003198284.1
	PHYH	XP_001085862.2
Canis lupus familiaris (dog)	LOC478001	NP_001240650.1
Xenopus tropicalis (tropical clawed frog)	phyh	XP_002935288.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

Ataxia with loss of Purkinje cells in a mouse model for Refsum disease.
Ferdinandusse S, Zomer AW, Komen JC, van den Brink CE, Thanos M, Hamers FP, Wanders RJ, van der Saag PT, Poll-The BT, Brites P
Proceedings of the National Academy of Sciences of the United States of America105(46)17712-7(2008 Nov)

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
Brites P, Motley AM, Gressens P, Mooyer PA, Ploegaert I, Everts V, Evrard P, Carmeliet P, Dewerchin M, Schoonjans L, Duran M, Waterham HR, Wanders RJ, Baes M
Human molecular genetics12(18)2255-67(2003 Sep)

A novel murine long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation.
Kee HJ, Koh JT, Yang SY, Lee ZH, Baik YH, Kim KK
Biochemical and biophysical research communications305(4)925-33(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Phyh gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Phyh cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15003	NM_010726.2 Latest version!	Mus musculus phytanoyl-CoA hydroxylase (Phyh), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Phyh ( NM_010726.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034856.1 Mus musculus phytanoyl-CoA hydroxylase (Phyh), mRNA.

Price & Availability↑

CloneID	OMu15003
Clone ID Related Accession (Same CDS sequence)	NM_010726.2
Accession Version	NM_010726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	phytanoyl-CoA dioxygenase, peroxisomal precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY139974.1, AK146753.1 and BY369819.1. On Dec 11, 2007 this sequence version replaced NM_010726.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660821.59382.1, AK146753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAATCTTA CGCGCGCCGG CGCCCGGCTG CAGGTCCTTC TGGGACACCT CGGCCGACCC 
TCGGCCCCAA CGATTGTAGC CCAGCCTGTA TCAGGGTTGG CTTCCCCTGC CAGTTTCCAG 
CCTGAACAAT TCCAGTATAC TCTGGATAAT AATGTCCTCA CCCTGGAGCA GAGAAAATTT 
TATGAAGAAA ATGGGTTTCT CGTCATTAAG AATCTGGTAT CTGATGATGA CATTCAACGT 
TTTCGAGCAG AGTTTGAAAG AATCTGCAGA GAGGAGGTGA AACCACCAGG GATCGTTATA 
ATGAGAGATG TGGCCCTTGC AAAACAGGAT TATATGCCAA GTGATAGGAT GGTTTCAAAG 
ATCCAGGATT TCCAAGAAGA TGAGGAGCTC TTCAGATACT GCCTTCTCCC CGAGATTCTG 
AAGTATGTGG AGTGTTTCAC TGGACCCAAT ATTATGGCTC TGCATGGGAT GCTGATCAAC 
AAGCCTCCAG ATGTTGGCAA GAAGACATCC CGGCATCCCT TGCATCAGGA TCTGCACTAT 
TTCCCCTTCC GACCTAGCAA CCTAATTGTT TGTGCTTGGA CAGCCATGGA GCACATTGAC 
AGAAACAACG GTTGTCTGGT TGTGCTCCCA GGTACCCACA AAGGCACTCT GAAGCCACAT 
GATTACCCCA AGTGGGAGGG AGGTGTTAAC AAAATGTACC ATGGCATCCA AGACTATGAC 
CCCAACAGCC CCCGGGTCCA CCTAGTGATG GAAAAGGGCG ATACTGTTTT CTTCCACCCT 
CTGCTCATCC ATGGATCTGG TCGGAACAAA ACTCAAGGCT TCCGGAAAGC AATTTCCTGC 
CACTTCGGCA GCTCTGACTG CCAGTGTATC GATGTGAGCG GCACCAGTCA AGAAAATATT 
GCAAGGGAAG TTGTCGAGAT GGCAGAGAAA AAGTATGGAT TCCAAGGAGT CATGGACTTT 
AAGGACACTT GGATATTTCG AAGCCGACTT GTGAAAGGAG AAAGAATAAA CATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034856.1
CDS	75..1091
Translation	MNLTRAGARLQVLLGHLGRPSAPTIVAQPVSGLASPASFQPEQFQYTLDNNVLTLEQRKFYEENGFLVIKNLVSDDDIQRFRAEFERICREEVKPPGIVIMRDVALAKQDYMPSDRMVSKIQDFQEDEELFRYCLLPEILKYVECFTGPNIMALHGMLINKPPDVGKKTSRHPLHQDLHYFPFRPSNLIVCAWTAMEHIDRNNGCLVVLPGTHKGTLKPHDYPKWEGGVNKMYHGIQDYDPNSPRVHLVMEKGDTVFFHPLLIHGSGRNKTQGFRKAISCHFGSSDCQCIDVSGTSQENIAREVVEMAEKKYGFQGVMDFKDTWIFRSRLVKGERINI

Target ORF information:

RefSeq Version	NM_010726.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phytanoyl-CoA hydroxylase (Phyh), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010726.2

ORF Insert Sequence:

ATGAATCTTA CGCGCGCCGG CGCCCGGCTG CAGGTCCTTC TGGGACACCT CGGCCGACCC 
TCGGCCCCAA CGATTGTAGC CCAGCCTGTA TCAGGGTTGG CTTCCCCTGC CAGTTTCCAG 
CCTGAACAAT TCCAGTATAC TCTGGATAAT AATGTCCTCA CCCTGGAGCA GAGAAAATTT 
TATGAAGAAA ATGGGTTTCT CGTCATTAAG AATCTGGTAT CTGATGATGA CATTCAACGT 
TTTCGAGCAG AGTTTGAAAG AATCTGCAGA GAGGAGGTGA AACCACCAGG GATCGTTATA 
ATGAGAGATG TGGCCCTTGC AAAACAGGAT TATATGCCAA GTGATAGGAT GGTTTCAAAG 
ATCCAGGATT TCCAAGAAGA TGAGGAGCTC TTCAGATACT GCCTTCTCCC CGAGATTCTG 
AAGTATGTGG AGTGTTTCAC TGGACCCAAT ATTATGGCTC TGCATGGGAT GCTGATCAAC 
AAGCCTCCAG ATGTTGGCAA GAAGACATCC CGGCATCCCT TGCATCAGGA TCTGCACTAT 
TTCCCCTTCC GACCTAGCAA CCTAATTGTT TGTGCTTGGA CAGCCATGGA GCACATTGAC 
AGAAACAACG GTTGTCTGGT TGTGCTCCCA GGTACCCACA AAGGCACTCT GAAGCCACAT 
GATTACCCCA AGTGGGAGGG AGGTGTTAAC AAAATGTACC ATGGCATCCA AGACTATGAC 
CCCAACAGCC CCCGGGTCCA CCTAGTGATG GAAAAGGGCG ATACTGTTTT CTTCCACCCT 
CTGCTCATCC ATGGATCTGG TCGGAACAAA ACTCAAGGCT TCCGGAAAGC AATTTCCTGC 
CACTTCGGCA GCTCTGACTG CCAGTGTATC GATGTGAGCG GCACCAGTCA AGAAAATATT 
GCAAGGGAAG TTGTCGAGAT GGCAGAGAAA AAGTATGGAT TCCAAGGAGT CATGGACTTT 
AAGGACACTT GGATATTTCG AAGCCGACTT GTGAAAGGAG AAAGAATAAA CATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES

Ataxia with loss of Purkinje cells in a mouse model for Refsum disease.
Proceedings of the National Academy of Sciences of the United States of America105(46)17712-7(2008 Nov)
Ferdinandusse S,Zomer AW,Komen JC,van den Brink CE,Thanos M,Hamers FP,Wanders RJ,van der Saag PT,Poll-The BT,Brites P

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
Human molecular genetics12(18)2255-67(2003 Sep)
Brites P,Motley AM,Gressens P,Mooyer PA,Ploegaert I,Everts V,Evrard P,Carmeliet P,Dewerchin M,Schoonjans L,Duran M,Waterham HR,Wanders RJ,Baes M

A novel murine long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation.
Biochemical and biophysical research communications305(4)925-33(2003 Jun)
Kee HJ,Koh JT,Yang SY,Lee ZH,Baik YH,Kim KK

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Phyh cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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