Psmb9 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psmb9
Entrez Gene ID	16912
Full Name	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Synonyms	Lmp-2,Lmp2
General protein information	Preferred Names proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) Names proteasome subunit beta type-9 LMP-2d large multifunctional protease 2 low molecular mass protein 2 macropain chain 7 multicatalytic endopeptidase complex chain 7 proteasome chain 7 proteasome subunit beta-1i proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) proteosome beta 9 subunit really interesting new gene 12 protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 17.98 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006523730.2	XP_006523793.1	proteasome subunit beta type-9 isoform X1
NM_013585.2	NP_038613.1	proteasome subunit beta type-9
XM_006523730.3	XP_006523793.1	proteasome subunit beta type-9 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PSMB9	XP_001167429.1
Bos taurus (cattle)	PSMB9	NP_001029560.1
Rattus norvegicus (Norway rat)	Psmb9	NP_036840.2
Xenopus tropicalis (tropical clawed frog)	psmb9	NP_001003660.1
Homo sapiens (human)	PSMB9	NP_002791.1
	PSMB9	XP_001108087.2
Canis lupus familiaris (dog)	PSMB9	NP_001041551.1
Mus musculus (house mouse)	Psmb9	NP_038613.1
Danio rerio (zebrafish)	psmb9a	NP_571466.1

Gene Ontology
Bibliography

Related articles in PubMed

The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T?cell repertoire.
Basler M, Mundt S, Groettrup M
European journal of immunology(2017 Oct)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Although treatment with IFN-gamma strongly induced the activation of STAT1 as a transcriptional activator, its target molecule, IRF1, was not clearly produced in Lmp2-deficient uterine smooth muscle cells.
Title: Uterine Leiomyosarcoma Tumorigenesis in Lmp2-deficient Mice: Involvement of Impaired Anti-oncogenic Factor IRF1.

down-regulation of IL-33 protein levels by IFN-gamma in pulmonary fibroblasts and in the lungs in vivo occurs through STAT1 and non-canonical use of the LMP2 proteasome
Title: IFN-? directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism.

Data show that knockdown of i-proteasome catalytic subunit PSMB9 by short hairpin RNA (shRNA) decreased the expression of both PSMB9 and PSMB8 without affecting other catalytic subunits of the proteasome.
Title: Identification of the immunoproteasome as a novel regulator of skeletal muscle differentiation.

In this study, we have identified how LMP2 can exert its function in Ag processing
Title: Why the structure but not the activity of the immunoproteasome subunit low molecular mass polypeptide 2 rescues antigen presentation.

LMP2 has a role as a tumor-suppressor and may have a role in uterine leiomyosarcoma therapy
Title: Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.

The following Psmb9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psmb9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu23064	NM_013585.2 Latest version!	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu53195	XM_006523730.3 Latest version!	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu53195	XM_006523730.2	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psmb9 ( NM_013585.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038613.1 Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), mRNA.

Price & Availability↑

CloneID	OMu23064
Clone ID Related Accession (Same CDS sequence)	NM_013585.2
Accession Version	NM_013585.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	proteasome subunit beta type-9
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR974422.14. On Nov 17, 2006 this sequence version replaced NM_013585.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D44458.1, AK152743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCGGG CAGGAGCACC TACCGCCGGC TCGTTCCGGA CGGAAGAAGT CCACACCGGG 
ACAACCATCA TGGCAGTGGA GTTTGACGGG GGTGTCGTGG TGGGCTCTGA TTCCCGGGTG 
TCAGCGGGAA CAGCAGTGGT GAACCGCGTG TTCGACAAGC TCTCCCCTCT GCACCAGCAC 
ATCTTCTGTG CCCTCTCAGG TTCCGCTGCT GATGCCCAAG CCATAGCTGA CATGGCCGCC 
TACCAGCTGG AGCTACACGG GTTGGAGCTG GAGGAGCCGC CCCTCGTTCT GGCTGCTGCA 
AACGTGGTGA AGAACATCTC CTACAAGTAC CGTGAGGACT TGTTAGCGCA TCTCATAGTA 
GCTGGCTGGG ACCAATGTGA GGGGGGACAG GTATATGGAA CCATGGGAGG GATGCTAATT 
CGACAGCCCT TTACCATCGG CGGTTCCGGA AGCTCCTACA TTTATGGTTA TGTGGACGCA 
GCTTATAAGC CAGGCATGAC CCCTGAGGAG TGCCGGCGTT TCACCACAGA TGCCATCACT 
CTGGCCATGA ACCGAGATGG CTCTAGTGGG GGTGTCATCT ACCTGGTCAC CATCACAGCT 
GCTGGTGTGG ACCATCGAGT CATCCTGGGA GATGAGCTGC CAAAATTCTA CGATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038613.1
CDS	22..681
Translation	MLRAGAPTAGSFRTEEVHTGTTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQHIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQCEGGQVYGTMGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYLVTITAAGVDHRVILGDELPKFYDE

Target ORF information:

RefSeq Version	NM_013585.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013585.2

ORF Insert Sequence:

ATGCTGCGGG CAGGAGCACC TACCGCCGGC TCGTTCCGGA CGGAAGAAGT CCACACCGGG 
ACAACCATCA TGGCAGTGGA GTTTGACGGG GGTGTCGTGG TGGGCTCTGA TTCCCGGGTG 
TCAGCGGGAA CAGCAGTGGT GAACCGCGTG TTCGACAAGC TCTCCCCTCT GCACCAGCAC 
ATCTTCTGTG CCCTCTCAGG TTCCGCTGCT GATGCCCAAG CCATAGCTGA CATGGCCGCC 
TACCAGCTGG AGCTACACGG GTTGGAGCTG GAGGAGCCGC CCCTCGTTCT GGCTGCTGCA 
AACGTGGTGA AGAACATCTC CTACAAGTAC CGTGAGGACT TGTTAGCGCA TCTCATAGTA 
GCTGGCTGGG ACCAATGTGA GGGGGGACAG GTATATGGAA CCATGGGAGG GATGCTAATT 
CGACAGCCCT TTACCATCGG CGGTTCCGGA AGCTCCTACA TTTATGGTTA TGTGGACGCA 
GCTTATAAGC CAGGCATGAC CCCTGAGGAG TGCCGGCGTT TCACCACAGA TGCCATCACT 
CTGGCCATGA ACCGAGATGG CTCTAGTGGG GGTGTCATCT ACCTGGTCAC CATCACAGCT 
GCTGGTGTGG ACCATCGAGT CATCCTGGGA GATGAGCTGC CAAAATTCTA CGATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psmb9 ( XM_006523730.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006523793.1 Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53195
Clone ID Related Accession (Same CDS sequence)	XM_006523730.2 , XM_006523730.3
Accession Version	XM_006523730.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	proteasome subunit beta type-9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006523730.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGTGG AGTTTGACGG GGGTGTCGTG GTGGGCTCTG ATTCCCGGGT GTCAGCGGGA 
ACAGCAGTGG TGAACCGCGT GTTCGACAAG CTCTCCCCTC TGCACCAGCA CATCTTCTGT 
GCCCTCTCAG GTTCCGCTGC TGATGCCCAA GCCATAGCTG ACATGGCCGC CTACCAGCTG 
GAGCTACACG GGTTGGAGCT GGAGGAGCCG CCCCTCGTTC TGGCTGCTGC AAACGTGGTG 
AAGAACATCT CCTACAAGTA CCGTGAGGAC TTGTTAGCGC ATCTCATAGT AGCTGGCTGG 
GACCAATGTG AGGGGGGACA GGTATATGGA ACCATGGGAG GGATGCTAAT TCGACAGCCC 
TTTACCATCG GCGGTTCCGG AAGCTCCTAC ATTTATGGTT ATGTGGACGC AGCTTATAAG 
CCAGGCATGA CCCCTGAGGA GTGCCGGCGT TTCACCACAG ATGCCATCAC TCTGGCCATG 
AACCGAGATG GCTCTAGTGG GGGTGTCATC TACCTGGTCA CCATCACAGC TGCTGGTGTG 
GACCATCGAG TCATCCTGGG AGATGAGCTG CCAAAATTCT ACGATGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006523793.1
CDS	195..785
Translation	MAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQHIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQCEGGQVYGTMGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYLVTITAAGVDHRVILGDELPKFYDE

Target ORF information:

RefSeq Version	XM_006523730.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523730.2

ORF Insert Sequence:

ATGGCAGTGG AGTTTGACGG GGGTGTCGTG GTGGGCTCTG ATTCCCGGGT GTCAGCGGGA 
ACAGCAGTGG TGAACCGCGT GTTCGACAAG CTCTCCCCTC TGCACCAGCA CATCTTCTGT 
GCCCTCTCAG GTTCCGCTGC TGATGCCCAA GCCATAGCTG ACATGGCCGC CTACCAGCTG 
GAGCTACACG GGTTGGAGCT GGAGGAGCCG CCCCTCGTTC TGGCTGCTGC AAACGTGGTG 
AAGAACATCT CCTACAAGTA CCGTGAGGAC TTGTTAGCGC ATCTCATAGT AGCTGGCTGG 
GACCAATGTG AGGGGGGACA GGTATATGGA ACCATGGGAG GGATGCTAAT TCGACAGCCC 
TTTACCATCG GCGGTTCCGG AAGCTCCTAC ATTTATGGTT ATGTGGACGC AGCTTATAAG 
CCAGGCATGA CCCCTGAGGA GTGCCGGCGT TTCACCACAG ATGCCATCAC TCTGGCCATG 
AACCGAGATG GCTCTAGTGG GGGTGTCATC TACCTGGTCA CCATCACAGC TGCTGGTGTG 
GACCATCGAG TCATCCTGGG AGATGAGCTG CCAAAATTCT ACGATGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psmb9 ( XM_006523730.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006523793.1 Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53195
Clone ID Related Accession (Same CDS sequence)	XM_006523730.2 , XM_006523730.3
Accession Version	XM_006523730.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	proteasome subunit beta type-9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006523730.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGTGG AGTTTGACGG GGGTGTCGTG GTGGGCTCTG ATTCCCGGGT GTCAGCGGGA 
ACAGCAGTGG TGAACCGCGT GTTCGACAAG CTCTCCCCTC TGCACCAGCA CATCTTCTGT 
GCCCTCTCAG GTTCCGCTGC TGATGCCCAA GCCATAGCTG ACATGGCCGC CTACCAGCTG 
GAGCTACACG GGTTGGAGCT GGAGGAGCCG CCCCTCGTTC TGGCTGCTGC AAACGTGGTG 
AAGAACATCT CCTACAAGTA CCGTGAGGAC TTGTTAGCGC ATCTCATAGT AGCTGGCTGG 
GACCAATGTG AGGGGGGACA GGTATATGGA ACCATGGGAG GGATGCTAAT TCGACAGCCC 
TTTACCATCG GCGGTTCCGG AAGCTCCTAC ATTTATGGTT ATGTGGACGC AGCTTATAAG 
CCAGGCATGA CCCCTGAGGA GTGCCGGCGT TTCACCACAG ATGCCATCAC TCTGGCCATG 
AACCGAGATG GCTCTAGTGG GGGTGTCATC TACCTGGTCA CCATCACAGC TGCTGGTGTG 
GACCATCGAG TCATCCTGGG AGATGAGCTG CCAAAATTCT ACGATGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006523793.1
CDS	280..870
Translation	MAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQHIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQCEGGQVYGTMGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYLVTITAAGVDHRVILGDELPKFYDE

Target ORF information:

RefSeq Version	XM_006523730.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) (Psmb9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523730.3

ORF Insert Sequence:

ATGGCAGTGG AGTTTGACGG GGGTGTCGTG GTGGGCTCTG ATTCCCGGGT GTCAGCGGGA 
ACAGCAGTGG TGAACCGCGT GTTCGACAAG CTCTCCCCTC TGCACCAGCA CATCTTCTGT 
GCCCTCTCAG GTTCCGCTGC TGATGCCCAA GCCATAGCTG ACATGGCCGC CTACCAGCTG 
GAGCTACACG GGTTGGAGCT GGAGGAGCCG CCCCTCGTTC TGGCTGCTGC AAACGTGGTG 
AAGAACATCT CCTACAAGTA CCGTGAGGAC TTGTTAGCGC ATCTCATAGT AGCTGGCTGG 
GACCAATGTG AGGGGGGACA GGTATATGGA ACCATGGGAG GGATGCTAAT TCGACAGCCC 
TTTACCATCG GCGGTTCCGG AAGCTCCTAC ATTTATGGTT ATGTGGACGC AGCTTATAAG 
CCAGGCATGA CCCCTGAGGA GTGCCGGCGT TTCACCACAG ATGCCATCAC TCTGGCCATG 
AACCGAGATG GCTCTAGTGG GGGTGTCATC TACCTGGTCA CCATCACAGC TGCTGGTGTG 
GACCATCGAG TCATCCTGGG AGATGAGCTG CCAAAATTCT ACGATGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T?cell repertoire.
European journal of immunology(2017 Oct)
Basler M,Mundt S,Groettrup M

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

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Psmb9 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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