Lgals7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lgals7
Entrez Gene ID	16858
Full Name	lectin, galactose binding, soluble 7
Synonyms	Galectin-7,Pig1
General protein information	Preferred Names lectin, galactose binding, soluble 7 Names galectin-7 gal-7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006539569.3	XP_006539632.1	galectin-7 isoform X1
XM_006539569.2	XP_006539632.1	galectin-7 isoform X1
NM_008496.4	NP_032522.2	galectin-7

Pathways from BioSystems

Homologies

Homo sapiens (human)	LGALS7	NP_002298.1
	LGALS7	XP_001083444.1
Canis lupus familiaris (dog)	LGALS7B	XP_003432634.2
Homo sapiens (human)	LGALS7B	NP_001035972.1
Canis lupus familiaris (dog)	LOC100855989	XP_003638881.2
Bos taurus (cattle)	LGALS7	XP_002695021.1
Bos taurus (cattle)	LGALS7B	XP_002695023.2
Mus musculus (house mouse)	Lgals7	NP_032522.2
Rattus norvegicus (Norway rat)	Lgals7	NP_072104.2

Gene Ontology
Bibliography

Related articles in PubMed

High-glucose environment induced intracellular O-GlcNAc glycosylation and reduced galectin-7 expression in keratinocytes: Implications on impaired diabetic wound healing.
Huang SM, Wu CS, Chiu MH, Yang HJ, Chen GS, Lan CE
Journal of dermatological science87(2)168-175(2017 Aug)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer.
Grosset AA, Poirier F, Gaboury L, St-Pierre Y
PloS one11(11)e0166731(2016)

Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.
Gendronneau G, Sanii S, Dang T, Deshayes F, Delacour D, Pichard E, Advedissian T, Sidhu SS, Viguier M, Magnaldo T, Poirier F
PloS one10(3)e0119031(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data suggest that gal-7 could potentiate the phenotype of HER-2 positive primary breast cancer.
Title: Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer.

results indicate that an excess of galectin-7 leads to a destabilisation of adherens junctions associated with defects in epidermal repair
Title: Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.

In cardiac transplantation galectin-7 relates to acute allograft rejection and T-cell responses possibly as an accelerant.
Title: Galectin-7 in cardiac allografts in mice: increased expression compared with isografts and localization in infiltrating lymphocytes and vascular endothelial cells.

Overexpression of galectin-7 increased the resistance of melanoma cells to apoptosis while inducing de novo egr-1 expression.
Title: Expression and functions of galectin-7 in human and murine melanomas.

Extracellular superoxide dismutase plays a role not only as a reactive oxygen species scavenger, but also as a pro-apoptotic factor via COX-2/galectin-7 pathways in the epidermis.
Title: EC-SOD induces apoptosis through COX-2 and galectin-7 in the epidermis.

The following Lgals7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lgals7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02062	NM_008496.4 Latest version!	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu02062	XM_006539569.3 Latest version!	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu02062	XM_006539569.2	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lgals7 ( NM_008496.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032522.2 Mus musculus lectin, galactose binding, soluble 7 (Lgals7), mRNA.

Price & Availability↑

CloneID	OMu02062
Clone ID Related Accession (Same CDS sequence)	XM_006539569.3 , XM_006539569.2 , NM_008496.4
Accession Version	NM_008496.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	galectin-7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG803457.1 and AK003153.1. On Jul 2, 2004 this sequence version replaced NM_008496.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA451195.1, AK009151.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032522.2
CDS	96..506
Translation	MSATQHKTSLPQGVRVGTVMRIRGMVPDQAGRFHVNLLCGEEQGADAALHFNPRLDTSEVVFNTKEQGKWGREERGTGIPFERGQPFEVLLIATEEGFKAVVGDDEYLHFHHRMPPARVRLVEVGGDVQLHSVKIF

Target ORF information:

RefSeq Version	NM_008496.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008496.4

ORF Insert Sequence:

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lgals7 ( XM_006539569.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539632.1 Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02062
Clone ID Related Accession (Same CDS sequence)	XM_006539569.3 , XM_006539569.2 , NM_008496.4
Accession Version	XM_006539569.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	galectin-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006539569.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539632.1
CDS	156..566
Translation	MSATQHKTSLPQGVRVGTVMRIRGMVPDQAGRFHVNLLCGEEQGADAALHFNPRLDTSEVVFNTKEQGKWGREERGTGIPFERGQPFEVLLIATEEGFKAVVGDDEYLHFHHRMPPARVRLVEVGGDVQLHSVKIF

Target ORF information:

RefSeq Version	XM_006539569.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539569.2

ORF Insert Sequence:

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lgals7 ( XM_006539569.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539632.1 Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02062
Clone ID Related Accession (Same CDS sequence)	XM_006539569.3 , XM_006539569.2 , NM_008496.4
Accession Version	XM_006539569.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	galectin-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006539569.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539632.1
CDS	213..623
Translation	MSATQHKTSLPQGVRVGTVMRIRGMVPDQAGRFHVNLLCGEEQGADAALHFNPRLDTSEVVFNTKEQGKWGREERGTGIPFERGQPFEVLLIATEEGFKAVVGDDEYLHFHHRMPPARVRLVEVGGDVQLHSVKIF

Target ORF information:

RefSeq Version	XM_006539569.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lectin, galactose binding, soluble 7 (Lgals7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539569.3

ORF Insert Sequence:

ATGTCTGCTA CCCAGCACAA GACCTCCCTG CCTCAGGGCG TCCGCGTGGG CACTGTCATG 
AGAATTCGAG GCATGGTCCC TGACCAGGCT GGCAGGTTCC ATGTAAACCT GCTATGCGGT 
GAGGAGCAAG GAGCAGATGC CGCCTTGCAC TTTAACCCGA GGCTGGACAC TTCCGAGGTT 
GTCTTCAACA CCAAAGAACA AGGCAAATGG GGCCGTGAGG AGCGAGGCAC CGGCATCCCC 
TTCGAGCGTG GGCAGCCCTT TGAAGTGCTC CTCATCGCCA CAGAGGAAGG CTTCAAGGCT 
GTGGTCGGGG ATGACGAATA TCTCCACTTC CACCACCGGA TGCCGCCCGC GCGCGTGCGC 
TTGGTGGAGG TGGGCGGAGA CGTGCAGCTG CATTCAGTGA AGATCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-glucose environment induced intracellular O-GlcNAc glycosylation and reduced galectin-7 expression in keratinocytes: Implications on impaired diabetic wound healing.
Journal of dermatological science87(2)168-175(2017 Aug)
Huang SM,Wu CS,Chiu MH,Yang HJ,Chen GS,Lan CE

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer.
PloS one11(11)e0166731(2016)
Grosset AA,Poirier F,Gaboury L,St-Pierre Y

Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.
PloS one10(3)e0119031(2015)
Gendronneau G,Sanii S,Dang T,Deshayes F,Delacour D,Pichard E,Advedissian T,Sidhu SS,Viguier M,Magnaldo T,Poirier F

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Lgals7 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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