Lama4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lama4
Entrez Gene ID	16775
Full Name	laminin, alpha 4
General protein information	Preferred Names laminin, alpha 4 Names laminin subunit alpha-4 laminin [a]4 laminin-14 subunit alpha laminin-8 subunit alpha laminin-9 subunit alpha
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10 B1\|10 20.02 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010681.4	NP_034811.2	laminin subunit alpha-4 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LAMA4	NP_001098676.2
	LAMA4	XP_002803983.1
Bos taurus (cattle)	LAMA4	NP_001192894.1
Danio rerio (zebrafish)	lama4	NP_001034154.1
Pan troglodytes (chimpanzee)	LAMA4	XP_518696.3
Canis lupus familiaris (dog)	LAMA4	XP_005627847.1
Rattus norvegicus (Norway rat)	Lama4	XP_003752023.1
Gallus gallus (chicken)	LAMA4	XP_004940355.1
Mus musculus (house mouse)	Lama4	NP_034811.2
Xenopus tropicalis (tropical clawed frog)	lama4	XP_002936983.2

Gene Ontology
Bibliography

Related articles in PubMed

The Absence of Laminin ?4 in Male Mice Results in Enhanced Energy Expenditure and Increased Beige Subcutaneous Adipose Tissue.
Vaicik MK, Blagajcevic A, Ye H, Morse MC, Yang F, Goddi A, Brey EM, Cohen RN
Endocrinology159(1)356-367(2018 Jan)

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.
Furlan A, Dyachuk V, Kastriti ME, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko PV, Ernfors P, Adameyko I
Science (New York, N.Y.)357(6346)(2017 07)

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.
Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsd?ttir S
Human molecular genetics26(11)2018-2033(2017 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Lama4-/- NMJs demonstrated a decrease in miniature end-plate potential (EPP) frequency and increased amplitude of miniature EPPs and evoked EPPs.
Title: Loss of laminin-?4 results in pre- and postsynaptic modifications at the neuromuscular junction.

Results showed maintained perturbed transmission properties at lama4(-/-) NMJs from adult (3 months) through to aged (18-22 months). Hind-limb grip force demonstrated similar trends as transmission properties, with maintained weaker grip force across age groups in lama4(-/-). Interestingly, both transmission properties and hind-limb grip force in aged wild-types resembled those observed in adult lama4(-/-).
Title: Functional decline at the aging neuromuscular junction is associated with altered laminin-?4 expression.

Laminins affect T cell trafficking and allograft fate.
Title: Laminins affect T cell trafficking and allograft fate.

laminin alpha4 influences adipose tissue structure and function in a depot-specific manner.
Title: Laminin ?4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain.

synaptic laminin are required to maintain adult neuromuscular junctions.
Title: Agrin and synaptic laminin are required to maintain adult neuromuscular junctions.

The following Lama4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lama4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23026	NM_010681.4 Latest version!	Mus musculus laminin, alpha 4 (Lama4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	22	$1336.30 $1909.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lama4 ( NM_010681.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034811.2 Mus musculus laminin, alpha 4 (Lama4), mRNA.

Price & Availability↑

CloneID	OMu23026
Clone ID Related Accession (Same CDS sequence)	NM_010681.4
Accession Version	NM_010681.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	laminin subunit alpha-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118224.8, BC115942.1 and AC153958.2. On Jul 9, 2010 this sequence version replaced NM_010681.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U69176.1, Y09827.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGTTGGA GCACAGCTTG GTGCTCAGTC CTGGCCCTGT GGCTCCTCTG GTGTGCTGTC 
TGCTCCAACG CAGCGTCAGG GGACGGCAAT GCGTTTCCTT TTGACATCGA GGGGAGCGCA 
GTGGTCGGCA GGCAAGACCC ATCGGAGACT AGCGACTCAG GCGTGACACT GGGACGCCTG 
CCGCCTGCTG CTGAGAGATG TGACGCTGGA TTCTTCCGCA CACTGTCAGG AGAATGTGCA 
CCCTGTGACT GTAATGGCAA TTCCCATGAG TGCTTGGATG GCTCCGGATT CTGTCTGCAC 
TGCCAGCGGA ACACAACAGG AGAGCACTGT GAAAAATGTC TGGATGGCTA TATTGGAGAC 
TCCATCAGAG GCACACCCCG GTTCTGCCAG CCGTGCCCCT GTCCCTTGCC CCACCTGGCC 
AACTTTGCAG AATCCTGCTA CAGGAAAAAT GGAGCTGTTC GGTGTATTTG TAAAGAAAAC 
TATGTTGGAC CTAACTGTGA AAGATGTGCT CCTGGTTACT ATGGAAACCC CTTACTCATT 
GGAAGCACCT GTAAGAAATG TGACTGCAGT GGAAATTCGG ATCCCAACCT GATCTTTGAA 
GACTGTGATG AAATCACTGG CCAGTGCAGG AACTGCTTAC GAAATACCAC CGGATTCAAG 
TGTGAACGCT GTGCACCTGG TTACTATGGA GACGCCAGGA CAGCCAAGAA CTGTGCAGTG 
TGCAACTGTG GGGGCGGCCC GTGTGACAGT GTAACCGGAG AGTGCTTGGA AGAAGGATTT 
GAAGTCCCTA CAGGCTGTGA TAAGTGCGTC TGGGACTTGA CCGATGACCT GCGATTAGCA 
GCGCTCTCCA TCGAAGAGAG CAAATCCGGG CTGCTGAGCG TGTCCTCTGG CGCTGCGGCG 
CATAGACACG TGACCGACAT GAACTCTACC ATCCACCTCC TCAGAACAAG GCTGTCAGAA 
AGAGAAAACC AGTATACCCT AAGAAAGATA CAGATAAACA ACTCGGAGAA CACACTGAGA 
AGCCTCCTGC CTGATGTAGA GGGACTCCAT GAGAAGGGAA GTCAAGCCTC AAGAAAGGGT 
ATGCTGGTTG AGAAGGAAAG CATGGATACA ATTGACCAAG CAACCCATCT TGTCGAGCAA 
GCCCACAACA TGAGGGACAA AATCCAAGAG ATCAACAGCA AGATGCTCTA CTATGGAGAG 
AATCAGGAAC TTGGCCCCGA GGAAATAGCT GAGAAGCTGG TGTTGGCCCA GAAAATGCTG 
GAAGAGATCC GAAGCCGGCA GCCATTCCTC ACCCATCGGG AGCTGGTGGA TGAGGAGGCA 
GATGAGGCCC AGGAATTGCT GAGCCAAGCT GAGAACTGGC AGCGGCTGCA CAATGACACC 
CGCTCTTTAT TCCCCGTGGT GCTGGAGCAG CTGGACGACT ACAACGCTAA GCTGTCCGAC 
CTCCAGGAAT CCATTAACCA GGCCCTCGAC CATGTCAGGG ATGCAGAAGA CATGAATAGA 
GCCATCACTT TCAAGCAGCG GGACCATGAG AAACAACATG AGAGAGTGAA GGAACAGATG 
GAAGTTGTGG GTGCCTCTCT GAGTATGTCT GCAGACTCTC TTACCATACC TCAGCTCACT 
CTTGAGGAAC TTGATGAGAT AATAAAGAAT GCATCTGGAA TTTATGCAGA AATAGATGGA 
GCCAAAAATG AGCTGCAAGG AAAACTATCC AACCTGAGTA ACCTCAGTCA TGACTTGGTT 
CAGGAAGCTA CGGACCATGC ATACAATCTT CAACAGGAAG CCGATGAGCT AAGCAGAAAT 
TTGCACAGTT CAGACATGAA CGGGCTGGTA CAGAAGGCTT TGGATGCATC AAACGTCTAT 
GAAAATATCG CCAATTATGT CAGTGAAGCC AACGAAACAG CAGAACTTGC TCTGAATATC 
ACTGATCGAA TTTATGATGC TGTGAGTGGG ATTGACACGC AGATCATTTA CCATAAGGAT 
GAAAGTGACA ACCTTCTCAA TCAAGCCAGA GAGCTGCAGG CCAAGGCAGA TTCTAGCAAT 
GATGAAGCAG TGGCTGACAC CAGCAGGCGT GTGGGTGGAG CCCTGTGGAG GAAGGGCGCC 
CTCAGAGACA GACTGAATGA TGCTGTTAAG CAACTACAGG CAGCAGAGAG AGGGGACGCC 
CACCAGCGCC TGGGCCAGTC CAAGCTCTTC ATTGAGGAAG CTAACAAGAC GACAGCGGCT 
GTCCAACAGG TTACCACACC AATGGCTAAC AACCTCAGCA ACTGGTCCCA GAACCTGCAG 
ACCTTTGACT CATCTGCATA TAACACTGCA GTGGACTCTG CTCGGGACGC AGTGAGAAAC 
CTCACCGAGG TTGTCCCCCA GCTTCTGGAT CAGCTTCGTA CTGTGGAGCA GAAGCGGCCT 
GCAAGCAACA TTTCTGCCAG CATCCAGAGG ATCCGAGAGC TCATTGCTCA AACCAGGAGT 
GTCGCAAGCA AGATCCAAGT CTCCATGATG TTTGATGGCC AGTCAGCTGT CGAAGTGCAC 
CCCAAAGTCA GTGTGGATGA CCTGAAGGCC TTCACATCCA TCAGCTTGTA CATGAAGCCT 
CCTCCAAAGC CGGCAGAGCC CACTGGGGCC TGGGTAGCAG ATCAGTTTGT CCTCTACCTC 
GGAAGCAAAA ACGCCAAAAA AGAATACATG GGTCTGGCAA TCAAAAATGA TAACCTGGTA 
TACGTTTACA ATTTGGGGAT GAAAGATGTG GAAATTCTCC TGGATTCCAA GCCTGTGAGC 
TCCTGGCCCG CTTACTTTAG TATTGTCAAG ATTGAAAGGG TAGGGAAACA CGGAAAGGTG 
TTCTTGACAG TCCCCAGTCT CAGTAGCACA GCAGAAGAAA AGTTTATTAA GAAGGGGGAG 
TTTGCAGGAG ATGACTCCTT GCTGGATCTG ACCCCTGAGG ACACTGTGTT TTACGTTGGT 
GGGGTGCCTG CGAACTTCAA GCTCCCTGCC AGCTTAAACC TGCCCAGCTA CTCAGGCTGC 
CTAGAGCTGG CCACTCTGAA TAATGATGTG ATCAGCTTGT ACAACTTCAA GCACATCTAT 
AATATGGATC CATCAAAGTC AGTGCCCTGT GCCAGGGATA AACTGGCTTT CACTCAGAGT 
AGGGCTGCCA GCTACTTCTT CGATGGCTCC AGTTATGCAG TGGTGAGGGA CATCACGAGG 
AGAGGGAAGT TTGGTCAGGT GACTCGCTTT GACATAGAAA TCCGAACACC AGCTGACAAT 
GGCCTTGTGC TCCTGATGGT CAATGGCAGT ATGTTTTTCA GCCTCGAAAT GCGCAATGGC 
TACCTACATG TGTTCTATGA CTTTGGATTC AGCAATGGCC CCGTGCATCT TGAAGACACG 
TTGAAAAAAG CCCAGATTAA TGATGCGAAA TATCATGAGA TCTCAATCAT TTATCACAAC 
GACAAAAAAA TGATTTTGGT GGTGGACAGA CGGCACGTTA AGAGCACAGA CAATGAGAAG 
AAAAAGATTC CTTTCACGGA CATCTACATC GGAGGTGCGC CCCAAGAAGT CTTACAGTCC 
AGGACCCTAA GAGCACACCT TCCCCTAGAT ATCAACTTTA GGGGGTGCAT GAAGGGGTTC 
CAGTTCCAAA AGAAAGATTT CAATTTACTG GAGCAGACAG AAACCCTAGG AGTTGGTTAT 
GGATGCCCAG AGGACTCTCT GATATCTCGC AGAGCATATT TCAATGGGCA AAGTTTTATT 
GCTTCAATTC AGAAAATATC TTTCTTTGAT GGCTTTGAAG GAGGCTTCAA TTTCCGAACA 
TTACAGCCAA ATGGGTTACT ATTCTACTAC ACATCAGGGT CGGACGTGTT TTCCATTTCA 
CTGGACAACG GCACTGTTGT CATGGACGTA AAGGGCATCA AGGTCATGTC AACAGACAAG 
CAGTACCACG ATGGGCTGCC CCACTTCGTG GTCACCTCCA TCTCAGACAC AAGATATGAA 
CTGGTAGTAG ACAAAAGCCG ACTTCGAGGG AAGAATCCAA CAAAAGGGAA GGCAGAGCAG 
ACTCAAACAA CTGAGAAGAA GTTCTACTTT GGTGGCTCAC CCATCAGTCC TCAGTATGCT 
AATTTCACTG GATGTATAAG CAATGCCTAC TTTACCAGGT TGGATAGAGA TGTGGAAGTC 
GAAGACTTCC AGCGCTATTC TGAAAAGGTC CACACTTCAC TCTATGAGTG TCCGATTGAG 
TCGTCACCTC TGTTTCTCCT TCACAAAAAA GGAAAGAATT CCTCAAAGCC TAAAACAAAC 
AAACAGGGAG AGAAGAGTAA GGATGCGCCT TCATGGGATC CTATTGGCCT GAAGTTTCTG 
GAACAGAAAG CTCCAAGAGA TTCCCACTGC CACCTCTCCA GCAGCCCCAG GGCAATAGAA 
CATGCCTATC AATATGGCGG CACGGCCAAC AGTCGCCAGG AGTTTGAACA CGAACAAGGA 
GATTTTGGTG AAAAATCCCA GTTTGCCATT CGTCTGAAGA CCCGTTCCTC ACATGGGATG 
ATTTTCTATG TCTCAGACCA AGAAGAGAAT GATTTCATGA CCCTGTTCTT GGCCCATGGT 
CGCTTGGTCT TTATGTTTAA TGTTGGCCAT AAGAAACTGA AGATTAGAAG CCAGGAGAAA 
TACAATGATG GATTGTGGCA TGATGTGATA TTTATTCGGG AAAAGAGCAG TGGTCGACTG 
GTCATTGATG GTCTACGAGT CCTAGAAGAA AGGCTTCCCC CTAGTGGCGC TGCCTGGAAA 
ATCAAGGGTC CCATTTATCT GGGAGGAGTG GCTCCCGGAA GAGCCGTGAA AAATGTCCAG 
ATTACCTCCG TCTACAGCTT CAGTGGCTGC CTTGGCAATC TCCAGCTCAA TGGTGCCTCC 
ATCACCTCCG CTTCTCAAAC GTTTAGCGTG ACCCCTTGCT TTGAAGGGCC AATGGAAACA 
GGAACTTATT TTTCCACAGA AGGCGGCTAT GTGGTTCTAG ATGAGTCTTT CAATATTGGG 
TTAAAATTTG AAATTGCCTT TGAAGTCCGC CCCCGGAGCA GTTCTGGAAC CCTTGTCCAT 
GGCCACAGCG TCAACGGGGA ATACCTGAAC GTGCACATGA GAAACGGACA GGTCATAGTG 
AAGGTCAACA ACGGTGTCAG AGACTTTTCT ACCTCAGTAA CTCCCAAGCA GAATCTCTGT 
GATGGCAGAT GGCACAGAAT TACAGTTATT AGAGATTCAA ACGTGGTTCA GTTGGATGTA 
GACTCAGAAG TGAACCATGT AGTTGGGCCG TTGAATCCAA AGCCAGTTGA TCACAGGGAG 
CCTGTGTTTG TTGGAGGTGT TCCAGAGTCT TTACTGACAC CACGTTTGGC TCCCAGCAAA 
CCCTTCACCG GCTGCATCCG CCACTTTGTA ATTGACAGCC GCCCTGTGAG CTTCAGTAAA 
GCTGCCCTGG TCAGTGGTGC TGTGAGCATC AACTCCTGTC CCACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034811.2
CDS	441..5891
Translation	MGWSTAWCSVLALWLLWCAVCSNAASGDGNAFPFDIEGSAVVGRQDPSETSDSGVTLGRLPPAAERCDAGFFRTLSGECAPCDCNGNSHECLDGSGFCLHCQRNTTGEHCEKCLDGYIGDSIRGTPRFCQPCPCPLPHLANFAESCYRKNGAVRCICKENYVGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEITGQCRNCLRNTTGFKCERCAPGYYGDARTAKNCAVCNCGGGPCDSVTGECLEEGFEVPTGCDKCVWDLTDDLRLAALSIEESKSGLLSVSSGAAAHRHVTDMNSTIHLLRTRLSERENQYTLRKIQINNSENTLRSLLPDVEGLHEKGSQASRKGMLVEKESMDTIDQATHLVEQAHNMRDKIQEINSKMLYYGENQELGPEEIAEKLVLAQKMLEEIRSRQPFLTHRELVDEEADEAQELLSQAENWQRLHNDTRSLFPVVLEQLDDYNAKLSDLQESINQALDHVRDAEDMNRAITFKQRDHEKQHERVKEQMEVVGASLSMSADSLTIPQLTLEELDEIIKNASGIYAEIDGAKNELQGKLSNLSNLSHDLVQEATDHAYNLQQEADELSRNLHSSDMNGLVQKALDASNVYENIANYVSEANETAELALNITDRIYDAVSGIDTQIIYHKDESDNLLNQARELQAKADSSNDEAVADTSRRVGGALWRKGALRDRLNDAVKQLQAAERGDAHQRLGQSKLFIEEANKTTAAVQQVTTPMANNLSNWSQNLQTFDSSAYNTAVDSARDAVRNLTEVVPQLLDQLRTVEQKRPASNISASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHPKVSVDDLKAFTSISLYMKPPPKPAEPTGAWVADQFVLYLGSKNAKKEYMGLAIKNDNLVYVYNLGMKDVEILLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFAGDDSLLDLTPEDTVFYVGGVPANFKLPASLNLPSYSGCLELATLNNDVISLYNFKHIYNMDPSKSVPCARDKLAFTQSRAASYFFDGSSYAVVRDITRRGKFGQVTRFDIEIRTPADNGLVLLMVNGSMFFSLEMRNGYLHVFYDFGFSNGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSTDNEKKKIPFTDIYIGGAPQEVLQSRTLRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYTSGSDVFSISLDNGTVVMDVKGIKVMSTDKQYHDGLPHFVVTSISDTRYELVVDKSRLRGKNPTKGKAEQTQTTEKKFYFGGSPISPQYANFTGCISNAYFTRLDRDVEVEDFQRYSEKVHTSLYECPIESSPLFLLHKKGKNSSKPKTNKQGEKSKDAPSWDPIGLKFLEQKAPRDSHCHLSSSPRAIEHAYQYGGTANSRQEFEHEQGDFGEKSQFAIRLKTRSSHGMIFYVSDQEENDFMTLFLAHGRLVFMFNVGHKKLKIRSQEKYNDGLWHDVIFIREKSSGRLVIDGLRVLEERLPPSGAAWKIKGPIYLGGVAPGRAVKNVQITSVYSFSGCLGNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMRNGQVIVKVNNGVRDFSTSVTPKQNLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPVDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDSRPVSFSKAALVSGAVSINSCPTA

Target ORF information:

RefSeq Version	NM_010681.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus laminin, alpha 4 (Lama4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010681.4

ORF Insert Sequence:

ATGGGTTGGA GCACAGCTTG GTGCTCAGTC CTGGCCCTGT GGCTCCTCTG GTGTGCTGTC 
TGCTCCAACG CAGCGTCAGG GGACGGCAAT GCGTTTCCTT TTGACATCGA GGGGAGCGCA 
GTGGTCGGCA GGCAAGACCC ATCGGAGACT AGCGACTCAG GCGTGACACT GGGACGCCTG 
CCGCCTGCTG CTGAGAGATG TGACGCTGGA TTCTTCCGCA CACTGTCAGG AGAATGTGCA 
CCCTGTGACT GTAATGGCAA TTCCCATGAG TGCTTGGATG GCTCCGGATT CTGTCTGCAC 
TGCCAGCGGA ACACAACAGG AGAGCACTGT GAAAAATGTC TGGATGGCTA TATTGGAGAC 
TCCATCAGAG GCACACCCCG GTTCTGCCAG CCGTGCCCCT GTCCCTTGCC CCACCTGGCC 
AACTTTGCAG AATCCTGCTA CAGGAAAAAT GGAGCTGTTC GGTGTATTTG TAAAGAAAAC 
TATGTTGGAC CTAACTGTGA AAGATGTGCT CCTGGTTACT ATGGAAACCC CTTACTCATT 
GGAAGCACCT GTAAGAAATG TGACTGCAGT GGAAATTCGG ATCCCAACCT GATCTTTGAA 
GACTGTGATG AAATCACTGG CCAGTGCAGG AACTGCTTAC GAAATACCAC CGGATTCAAG 
TGTGAACGCT GTGCACCTGG TTACTATGGA GACGCCAGGA CAGCCAAGAA CTGTGCAGTG 
TGCAACTGTG GGGGCGGCCC GTGTGACAGT GTAACCGGAG AGTGCTTGGA AGAAGGATTT 
GAAGTCCCTA CAGGCTGTGA TAAGTGCGTC TGGGACTTGA CCGATGACCT GCGATTAGCA 
GCGCTCTCCA TCGAAGAGAG CAAATCCGGG CTGCTGAGCG TGTCCTCTGG CGCTGCGGCG 
CATAGACACG TGACCGACAT GAACTCTACC ATCCACCTCC TCAGAACAAG GCTGTCAGAA 
AGAGAAAACC AGTATACCCT AAGAAAGATA CAGATAAACA ACTCGGAGAA CACACTGAGA 
AGCCTCCTGC CTGATGTAGA GGGACTCCAT GAGAAGGGAA GTCAAGCCTC AAGAAAGGGT 
ATGCTGGTTG AGAAGGAAAG CATGGATACA ATTGACCAAG CAACCCATCT TGTCGAGCAA 
GCCCACAACA TGAGGGACAA AATCCAAGAG ATCAACAGCA AGATGCTCTA CTATGGAGAG 
AATCAGGAAC TTGGCCCCGA GGAAATAGCT GAGAAGCTGG TGTTGGCCCA GAAAATGCTG 
GAAGAGATCC GAAGCCGGCA GCCATTCCTC ACCCATCGGG AGCTGGTGGA TGAGGAGGCA 
GATGAGGCCC AGGAATTGCT GAGCCAAGCT GAGAACTGGC AGCGGCTGCA CAATGACACC 
CGCTCTTTAT TCCCCGTGGT GCTGGAGCAG CTGGACGACT ACAACGCTAA GCTGTCCGAC 
CTCCAGGAAT CCATTAACCA GGCCCTCGAC CATGTCAGGG ATGCAGAAGA CATGAATAGA 
GCCATCACTT TCAAGCAGCG GGACCATGAG AAACAACATG AGAGAGTGAA GGAACAGATG 
GAAGTTGTGG GTGCCTCTCT GAGTATGTCT GCAGACTCTC TTACCATACC TCAGCTCACT 
CTTGAGGAAC TTGATGAGAT AATAAAGAAT GCATCTGGAA TTTATGCAGA AATAGATGGA 
GCCAAAAATG AGCTGCAAGG AAAACTATCC AACCTGAGTA ACCTCAGTCA TGACTTGGTT 
CAGGAAGCTA CGGACCATGC ATACAATCTT CAACAGGAAG CCGATGAGCT AAGCAGAAAT 
TTGCACAGTT CAGACATGAA CGGGCTGGTA CAGAAGGCTT TGGATGCATC AAACGTCTAT 
GAAAATATCG CCAATTATGT CAGTGAAGCC AACGAAACAG CAGAACTTGC TCTGAATATC 
ACTGATCGAA TTTATGATGC TGTGAGTGGG ATTGACACGC AGATCATTTA CCATAAGGAT 
GAAAGTGACA ACCTTCTCAA TCAAGCCAGA GAGCTGCAGG CCAAGGCAGA TTCTAGCAAT 
GATGAAGCAG TGGCTGACAC CAGCAGGCGT GTGGGTGGAG CCCTGTGGAG GAAGGGCGCC 
CTCAGAGACA GACTGAATGA TGCTGTTAAG CAACTACAGG CAGCAGAGAG AGGGGACGCC 
CACCAGCGCC TGGGCCAGTC CAAGCTCTTC ATTGAGGAAG CTAACAAGAC GACAGCGGCT 
GTCCAACAGG TTACCACACC AATGGCTAAC AACCTCAGCA ACTGGTCCCA GAACCTGCAG 
ACCTTTGACT CATCTGCATA TAACACTGCA GTGGACTCTG CTCGGGACGC AGTGAGAAAC 
CTCACCGAGG TTGTCCCCCA GCTTCTGGAT CAGCTTCGTA CTGTGGAGCA GAAGCGGCCT 
GCAAGCAACA TTTCTGCCAG CATCCAGAGG ATCCGAGAGC TCATTGCTCA AACCAGGAGT 
GTCGCAAGCA AGATCCAAGT CTCCATGATG TTTGATGGCC AGTCAGCTGT CGAAGTGCAC 
CCCAAAGTCA GTGTGGATGA CCTGAAGGCC TTCACATCCA TCAGCTTGTA CATGAAGCCT 
CCTCCAAAGC CGGCAGAGCC CACTGGGGCC TGGGTAGCAG ATCAGTTTGT CCTCTACCTC 
GGAAGCAAAA ACGCCAAAAA AGAATACATG GGTCTGGCAA TCAAAAATGA TAACCTGGTA 
TACGTTTACA ATTTGGGGAT GAAAGATGTG GAAATTCTCC TGGATTCCAA GCCTGTGAGC 
TCCTGGCCCG CTTACTTTAG TATTGTCAAG ATTGAAAGGG TAGGGAAACA CGGAAAGGTG 
TTCTTGACAG TCCCCAGTCT CAGTAGCACA GCAGAAGAAA AGTTTATTAA GAAGGGGGAG 
TTTGCAGGAG ATGACTCCTT GCTGGATCTG ACCCCTGAGG ACACTGTGTT TTACGTTGGT 
GGGGTGCCTG CGAACTTCAA GCTCCCTGCC AGCTTAAACC TGCCCAGCTA CTCAGGCTGC 
CTAGAGCTGG CCACTCTGAA TAATGATGTG ATCAGCTTGT ACAACTTCAA GCACATCTAT 
AATATGGATC CATCAAAGTC AGTGCCCTGT GCCAGGGATA AACTGGCTTT CACTCAGAGT 
AGGGCTGCCA GCTACTTCTT CGATGGCTCC AGTTATGCAG TGGTGAGGGA CATCACGAGG 
AGAGGGAAGT TTGGTCAGGT GACTCGCTTT GACATAGAAA TCCGAACACC AGCTGACAAT 
GGCCTTGTGC TCCTGATGGT CAATGGCAGT ATGTTTTTCA GCCTCGAAAT GCGCAATGGC 
TACCTACATG TGTTCTATGA CTTTGGATTC AGCAATGGCC CCGTGCATCT TGAAGACACG 
TTGAAAAAAG CCCAGATTAA TGATGCGAAA TATCATGAGA TCTCAATCAT TTATCACAAC 
GACAAAAAAA TGATTTTGGT GGTGGACAGA CGGCACGTTA AGAGCACAGA CAATGAGAAG 
AAAAAGATTC CTTTCACGGA CATCTACATC GGAGGTGCGC CCCAAGAAGT CTTACAGTCC 
AGGACCCTAA GAGCACACCT TCCCCTAGAT ATCAACTTTA GGGGGTGCAT GAAGGGGTTC 
CAGTTCCAAA AGAAAGATTT CAATTTACTG GAGCAGACAG AAACCCTAGG AGTTGGTTAT 
GGATGCCCAG AGGACTCTCT GATATCTCGC AGAGCATATT TCAATGGGCA AAGTTTTATT 
GCTTCAATTC AGAAAATATC TTTCTTTGAT GGCTTTGAAG GAGGCTTCAA TTTCCGAACA 
TTACAGCCAA ATGGGTTACT ATTCTACTAC ACATCAGGGT CGGACGTGTT TTCCATTTCA 
CTGGACAACG GCACTGTTGT CATGGACGTA AAGGGCATCA AGGTCATGTC AACAGACAAG 
CAGTACCACG ATGGGCTGCC CCACTTCGTG GTCACCTCCA TCTCAGACAC AAGATATGAA 
CTGGTAGTAG ACAAAAGCCG ACTTCGAGGG AAGAATCCAA CAAAAGGGAA GGCAGAGCAG 
ACTCAAACAA CTGAGAAGAA GTTCTACTTT GGTGGCTCAC CCATCAGTCC TCAGTATGCT 
AATTTCACTG GATGTATAAG CAATGCCTAC TTTACCAGGT TGGATAGAGA TGTGGAAGTC 
GAAGACTTCC AGCGCTATTC TGAAAAGGTC CACACTTCAC TCTATGAGTG TCCGATTGAG 
TCGTCACCTC TGTTTCTCCT TCACAAAAAA GGAAAGAATT CCTCAAAGCC TAAAACAAAC 
AAACAGGGAG AGAAGAGTAA GGATGCGCCT TCATGGGATC CTATTGGCCT GAAGTTTCTG 
GAACAGAAAG CTCCAAGAGA TTCCCACTGC CACCTCTCCA GCAGCCCCAG GGCAATAGAA 
CATGCCTATC AATATGGCGG CACGGCCAAC AGTCGCCAGG AGTTTGAACA CGAACAAGGA 
GATTTTGGTG AAAAATCCCA GTTTGCCATT CGTCTGAAGA CCCGTTCCTC ACATGGGATG 
ATTTTCTATG TCTCAGACCA AGAAGAGAAT GATTTCATGA CCCTGTTCTT GGCCCATGGT 
CGCTTGGTCT TTATGTTTAA TGTTGGCCAT AAGAAACTGA AGATTAGAAG CCAGGAGAAA 
TACAATGATG GATTGTGGCA TGATGTGATA TTTATTCGGG AAAAGAGCAG TGGTCGACTG 
GTCATTGATG GTCTACGAGT CCTAGAAGAA AGGCTTCCCC CTAGTGGCGC TGCCTGGAAA 
ATCAAGGGTC CCATTTATCT GGGAGGAGTG GCTCCCGGAA GAGCCGTGAA AAATGTCCAG 
ATTACCTCCG TCTACAGCTT CAGTGGCTGC CTTGGCAATC TCCAGCTCAA TGGTGCCTCC 
ATCACCTCCG CTTCTCAAAC GTTTAGCGTG ACCCCTTGCT TTGAAGGGCC AATGGAAACA 
GGAACTTATT TTTCCACAGA AGGCGGCTAT GTGGTTCTAG ATGAGTCTTT CAATATTGGG 
TTAAAATTTG AAATTGCCTT TGAAGTCCGC CCCCGGAGCA GTTCTGGAAC CCTTGTCCAT 
GGCCACAGCG TCAACGGGGA ATACCTGAAC GTGCACATGA GAAACGGACA GGTCATAGTG 
AAGGTCAACA ACGGTGTCAG AGACTTTTCT ACCTCAGTAA CTCCCAAGCA GAATCTCTGT 
GATGGCAGAT GGCACAGAAT TACAGTTATT AGAGATTCAA ACGTGGTTCA GTTGGATGTA 
GACTCAGAAG TGAACCATGT AGTTGGGCCG TTGAATCCAA AGCCAGTTGA TCACAGGGAG 
CCTGTGTTTG TTGGAGGTGT TCCAGAGTCT TTACTGACAC CACGTTTGGC TCCCAGCAAA 
CCCTTCACCG GCTGCATCCG CCACTTTGTA ATTGACAGCC GCCCTGTGAG CTTCAGTAAA 
GCTGCCCTGG TCAGTGGTGC TGTGAGCATC AACTCCTGTC CCACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Absence of Laminin ?4 in Male Mice Results in Enhanced Energy Expenditure and Increased Beige Subcutaneous Adipose Tissue.
Endocrinology159(1)356-367(2018 Jan)
Vaicik MK,Blagajcevic A,Ye H,Morse MC,Yang F,Goddi A,Brey EM,Cohen RN

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.
Science (New York, N.Y.)357(6346)(2017 07)
Furlan A,Dyachuk V,Kastriti ME,Calvo-Enrique L,Abdo H,Hadjab S,Chontorotzea T,Akkuratova N,Usoskin D,Kamenev D,Petersen J,Sunadome K,Memic F,Marklund U,Fried K,Topilko P,Lallemend F,Kharchenko PV,Ernfors P,Adameyko I

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.
Human molecular genetics26(11)2018-2033(2017 06)
Nunes AM,Wuebbles RD,Sarathy A,Fontelonga TM,Deries M,Burkin DJ,Thorsteinsd?ttir S

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Lama4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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