Kpna1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kpna1
Entrez Gene ID	16646
Full Name	karyopherin (importin) alpha 1
Synonyms	AW494490,IPOA5,NPI1,Rch2,mSRP1
General protein information	Preferred Names karyopherin (importin) alpha 1 Names importin subunit alpha-5 NPI-1 RAG cohort protein 2 SRP1-beta importin alpha 5 importin alpha-S1 importin subunit alpha-1 karyopherin subunit alpha-1 m-importin-alpha-S1 nucleoprotein interactor 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006521814.2	XP_006521877.1	importin subunit alpha-5 isoform X1
XM_006521814.3	XP_006521877.1	importin subunit alpha-5 isoform X1
XM_006521814.4	XP_006521877.1	importin subunit alpha-5 isoform X1
XM_030248989.1	XP_030104849.1	importin subunit alpha-5 isoform X2
NM_008465.5	NP_032491.2	importin subunit alpha-5
XM_011245834.2	XP_011244136.1	importin subunit alpha-5 isoform X2

Pathways from BioSystems

Homologies

	KPNA1	XP_001112537.1
Canis lupus familiaris (dog)	KPNA1	XP_005639616.1
Bos taurus (cattle)	KPNA1	NP_001075202.1
Pan troglodytes (chimpanzee)	KPNA1	XP_001167086.1
Gallus gallus (chicken)	KPNA1	NP_001025945.1
Homo sapiens (human)	KPNA1	NP_002255.3
Rattus norvegicus (Norway rat)	Kpna1	NP_942021.2
Danio rerio (zebrafish)	kpna1	XP_701359.5
Xenopus tropicalis (tropical clawed frog)	kpna1	NP_989192.1
Mus musculus (house mouse)	Kpna1	NP_032491.2
Arabidopsis thaliana (thale cress)	IMPA-4	NP_172398.1

Gene Ontology
Bibliography

Related articles in PubMed

Importin ?1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
D?hner K, Ramos-Nascimento A, Bialy D, Anderson F, Hickford-Martinez A, Rother F, Koithan T, Rudolph K, Buch A, Prank U, Binz A, H?gel S, Lebbink RJ, Hoeben RC, Hartmann E, Bader M, Bauerfeind R, Sodeik B
PLoS pathogens14(1)e1006823(2018 Jan)

The Transcriptional Activator Kr?ppel-like Factor-6 Is Required for CNS Myelination.
Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR
PLoS biology14(5)e1002467(2016 May)

Three distinct classes of the alpha-subunit of the nuclear pore-targeting complex (importin-alpha) are differentially expressed in adult mouse tissues.
Kamei Y, Yuba S, Nakayama T, Yoneda Y
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society47(3)363-72(1999 Mar)

Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression.
Tsuji L, Takumi T, Imamoto N, Yoneda Y
FEBS letters416(1)30-4(1997 Oct)

Localization of the importin-beta gene to mouse chromosome 11D and rat chromosome 10q32.1.
Matsuda Y, Hamatani K, Itoh M, Takahashi EI, Araki R, Abe M
Genomics36(1)213-5(1996 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mTOR and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 by KPNA1, which are key modulators of STAT1 expression and apoptosis.
Title: Regulation of karyopherin ?1 and nuclear import by mammalian target of rapamycin.

KPNA1 knockdown increased myoblast proliferation.
Title: Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells.

Absence of importin a5 during mouse development does not significantly interfere with neuronal differentiation and brain development.
Title: Normal brain development in importin-alpha5 deficient-mice.

Here, we show that the expression of importin-alpha subtypes is strictly regulated during neural differentiation of mouse embryonic stem (ES) cells, and that the switching of importin-alpha subtype expression is critical for neural differentiation.
Title: Triggering neural differentiation of ES cells by subtype switching of importin-alpha.

PTH1R forms a complex with the transport regulatory proteins, importin alpha(1) and importin beta, and nuclear PTH1R is associated with the nucleoplasm
Title: Type 1 parathyroid hormone receptor (PTH1R) nuclear trafficking: association of PTH1R with importin alpha1 and beta.

The following Kpna1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kpna1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu68102	XM_011245834.2 Latest version!	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu68102	XM_030248989.1 Latest version!	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu01989	NM_008465.5 Latest version!	Mus musculus karyopherin (importin) alpha 1 (Kpna1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu01989	XM_006521814.4 Latest version!	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu01989	XM_006521814.2	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu01989	XM_006521814.3	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kpna1 ( XM_011245834.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244136.1 Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu68102
Clone ID Related Accession (Same CDS sequence)	XM_030248989.1 , XM_011245834.2
Accession Version	XM_011245834.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011245834.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAGGG ACTATGTCTT AAACTGCAAT ATCCTTCCTC CTCTTCTGCA GTTATTTTCA 
AAGCAAAACC GCTTGACCAT GACCCGGAAT GCAGTATGGG CTTTATCTAA TCTCTGTAGA 
GGGAAGAGCC CACCTCCAGA ATTTGCTAAG GTTTCTCCCT GTCTGAATGT CCTTTCTTGG 
TTACTGTTTG TCAGTGACAC TGATGTACTA GCTGATGCTT GCTGGGCTCT CTCATACCTG 
TCAGATGGAC CCAATGATAA AATCCAAGCA GTCATCGATG CAGGAGTCTG CAGGAGGCTT 
GTGGAACTTC TGATGCATAA TGACTATAAA GTAGTTTCTC CTGCTTTGCG GGCTGTGGGA 
AACATTGTCA CAGGGGATGA TATTCAGACA CAGGTAATTT TGAATTGCTC AGCTCTTCAA 
AGTTTATTGC ATCTGCTGAG TAGCCCAAAG GAATCTATCA AAAAAGAAGC CTGTTGGACA 
ATCTCTAATA TTACAGCTGG AAATAGGGCA CAGATCCAGA CTGTGATAGA TGCTAACATG 
TTCCCAGCTC TTATTAGTAT ATTGCAAACA GCAGAGTTCC GGACAAGGAA GGAAGCTGCT 
TGGGCCATCA CAAATGCAAC TTCTGGAGGA TCAGCTGAGC AGATCAAGTA CCTAGTAGAA 
CTGGGTTGTA TCAAGCCACT CTGTGATCTC CTCACTGTCA TGGATGCAAA AATTGTACAG 
GTTGCCCTAA ATGGCTTAGA AAACATCCTG AGGCTTGGAG AACAAGAAGC CAAACGAAAC 
GGCTCAGGCA TTAATCCTTA CTGTGCTTTG ATTGAGGAAG CATATGGTCT GGATAAAATT 
GAGTTCTTAC AGAGTCATGA AAACCAGGAG ATCTATCAAA AGGCTTTTGA TCTTATTGAG 
CATTACTTTG GGACCGAAGA TGAGGACAGC AGCATCGCAC CCCAGGTTGA TCTTAGCCAG 
CAGCAGTACA TCTTCCAGCA GTGTGAAGCT CCTATGGAAG GTTTCCAGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244136.1
CDS	382..1395
Translation	MCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	XM_011245834.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245834.2

ORF Insert Sequence:

ATGTGCAGGG ACTATGTCTT AAACTGCAAT ATCCTTCCTC CTCTTCTGCA GTTATTTTCA 
AAGCAAAACC GCTTGACCAT GACCCGGAAT GCAGTATGGG CTTTATCTAA TCTCTGTAGA 
GGGAAGAGCC CACCTCCAGA ATTTGCTAAG GTTTCTCCCT GTCTGAATGT CCTTTCTTGG 
TTACTGTTTG TCAGTGACAC TGATGTACTA GCTGATGCTT GCTGGGCTCT CTCATACCTG 
TCAGATGGAC CCAATGATAA AATCCAAGCA GTCATCGATG CAGGAGTCTG CAGGAGGCTT 
GTGGAACTTC TGATGCATAA TGACTATAAA GTAGTTTCTC CTGCTTTGCG GGCTGTGGGA 
AACATTGTCA CAGGGGATGA TATTCAGACA CAGGTAATTT TGAATTGCTC AGCTCTTCAA 
AGTTTATTGC ATCTGCTGAG TAGCCCAAAG GAATCTATCA AAAAAGAAGC CTGTTGGACA 
ATCTCTAATA TTACAGCTGG AAATAGGGCA CAGATCCAGA CTGTGATAGA TGCTAACATG 
TTCCCAGCTC TTATTAGTAT ATTGCAAACA GCAGAGTTCC GGACAAGGAA GGAAGCTGCT 
TGGGCCATCA CAAATGCAAC TTCTGGAGGA TCAGCTGAGC AGATCAAGTA CCTAGTAGAA 
CTGGGTTGTA TCAAGCCACT CTGTGATCTC CTCACTGTCA TGGATGCAAA AATTGTACAG 
GTTGCCCTAA ATGGCTTAGA AAACATCCTG AGGCTTGGAG AACAAGAAGC CAAACGAAAC 
GGCTCAGGCA TTAATCCTTA CTGTGCTTTG ATTGAGGAAG CATATGGTCT GGATAAAATT 
GAGTTCTTAC AGAGTCATGA AAACCAGGAG ATCTATCAAA AGGCTTTTGA TCTTATTGAG 
CATTACTTTG GGACCGAAGA TGAGGACAGC AGCATCGCAC CCCAGGTTGA TCTTAGCCAG 
CAGCAGTACA TCTTCCAGCA GTGTGAAGCT CCTATGGAAG GTTTCCAGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna1 ( XM_030248989.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030104849.1 Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu68102
Clone ID Related Accession (Same CDS sequence)	XM_030248989.1 , XM_011245834.2
Accession Version	XM_030248989.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAGGG ACTATGTCTT AAACTGCAAT ATCCTTCCTC CTCTTCTGCA GTTATTTTCA 
AAGCAAAACC GCTTGACCAT GACCCGGAAT GCAGTATGGG CTTTATCTAA TCTCTGTAGA 
GGGAAGAGCC CACCTCCAGA ATTTGCTAAG GTTTCTCCCT GTCTGAATGT CCTTTCTTGG 
TTACTGTTTG TCAGTGACAC TGATGTACTA GCTGATGCTT GCTGGGCTCT CTCATACCTG 
TCAGATGGAC CCAATGATAA AATCCAAGCA GTCATCGATG CAGGAGTCTG CAGGAGGCTT 
GTGGAACTTC TGATGCATAA TGACTATAAA GTAGTTTCTC CTGCTTTGCG GGCTGTGGGA 
AACATTGTCA CAGGGGATGA TATTCAGACA CAGGTAATTT TGAATTGCTC AGCTCTTCAA 
AGTTTATTGC ATCTGCTGAG TAGCCCAAAG GAATCTATCA AAAAAGAAGC CTGTTGGACA 
ATCTCTAATA TTACAGCTGG AAATAGGGCA CAGATCCAGA CTGTGATAGA TGCTAACATG 
TTCCCAGCTC TTATTAGTAT ATTGCAAACA GCAGAGTTCC GGACAAGGAA GGAAGCTGCT 
TGGGCCATCA CAAATGCAAC TTCTGGAGGA TCAGCTGAGC AGATCAAGTA CCTAGTAGAA 
CTGGGTTGTA TCAAGCCACT CTGTGATCTC CTCACTGTCA TGGATGCAAA AATTGTACAG 
GTTGCCCTAA ATGGCTTAGA AAACATCCTG AGGCTTGGAG AACAAGAAGC CAAACGAAAC 
GGCTCAGGCA TTAATCCTTA CTGTGCTTTG ATTGAGGAAG CATATGGTCT GGATAAAATT 
GAGTTCTTAC AGAGTCATGA AAACCAGGAG ATCTATCAAA AGGCTTTTGA TCTTATTGAG 
CATTACTTTG GGACCGAAGA TGAGGACAGC AGCATCGCAC CCCAGGTTGA TCTTAGCCAG 
CAGCAGTACA TCTTCCAGCA GTGTGAAGCT CCTATGGAAG GTTTCCAGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030104849.1
CDS	952..1965
Translation	MCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	XM_030248989.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248989.1

ORF Insert Sequence:

ATGTGCAGGG ACTATGTCTT AAACTGCAAT ATCCTTCCTC CTCTTCTGCA GTTATTTTCA 
AAGCAAAACC GCTTGACCAT GACCCGGAAT GCAGTATGGG CTTTATCTAA TCTCTGTAGA 
GGGAAGAGCC CACCTCCAGA ATTTGCTAAG GTTTCTCCCT GTCTGAATGT CCTTTCTTGG 
TTACTGTTTG TCAGTGACAC TGATGTACTA GCTGATGCTT GCTGGGCTCT CTCATACCTG 
TCAGATGGAC CCAATGATAA AATCCAAGCA GTCATCGATG CAGGAGTCTG CAGGAGGCTT 
GTGGAACTTC TGATGCATAA TGACTATAAA GTAGTTTCTC CTGCTTTGCG GGCTGTGGGA 
AACATTGTCA CAGGGGATGA TATTCAGACA CAGGTAATTT TGAATTGCTC AGCTCTTCAA 
AGTTTATTGC ATCTGCTGAG TAGCCCAAAG GAATCTATCA AAAAAGAAGC CTGTTGGACA 
ATCTCTAATA TTACAGCTGG AAATAGGGCA CAGATCCAGA CTGTGATAGA TGCTAACATG 
TTCCCAGCTC TTATTAGTAT ATTGCAAACA GCAGAGTTCC GGACAAGGAA GGAAGCTGCT 
TGGGCCATCA CAAATGCAAC TTCTGGAGGA TCAGCTGAGC AGATCAAGTA CCTAGTAGAA 
CTGGGTTGTA TCAAGCCACT CTGTGATCTC CTCACTGTCA TGGATGCAAA AATTGTACAG 
GTTGCCCTAA ATGGCTTAGA AAACATCCTG AGGCTTGGAG AACAAGAAGC CAAACGAAAC 
GGCTCAGGCA TTAATCCTTA CTGTGCTTTG ATTGAGGAAG CATATGGTCT GGATAAAATT 
GAGTTCTTAC AGAGTCATGA AAACCAGGAG ATCTATCAAA AGGCTTTTGA TCTTATTGAG 
CATTACTTTG GGACCGAAGA TGAGGACAGC AGCATCGCAC CCCAGGTTGA TCTTAGCCAG 
CAGCAGTACA TCTTCCAGCA GTGTGAAGCT CCTATGGAAG GTTTCCAGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna1 ( NM_008465.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032491.2 Mus musculus karyopherin (importin) alpha 1 (Kpna1), mRNA.

Price & Availability↑

CloneID	OMu01989
Clone ID Related Accession (Same CDS sequence)	XM_006521814.2 , XM_006521814.3 , XM_006521814.4 , NM_008465.5
Accession Version	NM_008465.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133464.11 and CT573031.6. On Oct 20, 2007 this sequence version replaced NM_008465.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028259.1, AK154800.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032491.2
CDS	152..1768
Translation	MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	NM_008465.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008465.5

ORF Insert Sequence:

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna1 ( XM_006521814.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521877.1 Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

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CloneID	OMu01989
Clone ID Related Accession (Same CDS sequence)	XM_006521814.2 , XM_006521814.3 , XM_006521814.4 , NM_008465.5
Accession Version	XM_006521814.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	importin subunit alpha-5 isoform X1
Comment

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006521877.1

Translation

MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	XM_006521814.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521814.2

ORF Insert Sequence:

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna1 ( XM_006521814.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521877.1 Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01989
Clone ID Related Accession (Same CDS sequence)	XM_006521814.2 , XM_006521814.3 , XM_006521814.4 , NM_008465.5
Accession Version	XM_006521814.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521814.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521877.1
CDS	146..1762
Translation	MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	XM_006521814.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521814.3

ORF Insert Sequence:

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna1 ( XM_006521814.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521877.1 Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01989
Clone ID Related Accession (Same CDS sequence)	XM_006521814.2 , XM_006521814.3 , XM_006521814.4 , NM_008465.5
Accession Version	XM_006521814.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521814.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521877.1
CDS	379..1995
Translation	MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL

Target ORF information:

RefSeq Version	XM_006521814.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin (importin) alpha 1 (Kpna1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521814.4

ORF Insert Sequence:

ATGTCCACAC CAGGAAAAGA GAACTTTCGC CTGAAAAGTT ACAAGAACAA ATCTCTGAAT 
CCTGATGAGA TGCGCAGGAG GAGGGAGGAA GAAGGACTGC AGTTACGGAA GCAGAAAAGA 
GAAGAGCAGT TATTCAAGAG AAGAAATGTT GCTACAGCAG AAGAAGAAAC AGAAGAAGAA 
GTTATGTCTG ATGGTGGCTT TCATGAGGCC CAGATAAATA ACATGGAGAT GGCACCAGGG 
GGTGTCATCA CCTCTGACAT GACTGATATG ATATTCTCGA ATAGCCCAGA GCAGCAGCTC 
TCTGCAACAC AGAAGTTTAG GAAACTACTT TCAAAAGAAC CTAATCCTCC AATTGATGAA 
GTCATCAACA CACCAGGAGT AGTGGCCAGG TTTGTGGAGT TCCTCAAACG AAAAGAAAAT 
TGTACACTGC AGTTTGAATC AGCTTGGGTC CTGACAAATA TTGCTTCAGG AAACTCTCTT 
CAGACCCGGA ATGTGATTCA GGCAGGAGCT GTGCCTATTT TCATCGAGTT GCTTAGCTCA 
GAGTTTGAAG ATGTCCAGGA GCAGGCAGTT TGGGCTCTTG GCAACATTGC TGGAGATAGT 
ACCATGTGCA GGGACTATGT CTTAAACTGC AATATCCTTC CTCCTCTTCT GCAGTTATTT 
TCAAAGCAAA ACCGCTTGAC CATGACCCGG AATGCAGTAT GGGCTTTATC TAATCTCTGT 
AGAGGGAAGA GCCCACCTCC AGAATTTGCT AAGGTTTCTC CCTGTCTGAA TGTCCTTTCT 
TGGTTACTGT TTGTCAGTGA CACTGATGTA CTAGCTGATG CTTGCTGGGC TCTCTCATAC 
CTGTCAGATG GACCCAATGA TAAAATCCAA GCAGTCATCG ATGCAGGAGT CTGCAGGAGG 
CTTGTGGAAC TTCTGATGCA TAATGACTAT AAAGTAGTTT CTCCTGCTTT GCGGGCTGTG 
GGAAACATTG TCACAGGGGA TGATATTCAG ACACAGGTAA TTTTGAATTG CTCAGCTCTT 
CAAAGTTTAT TGCATCTGCT GAGTAGCCCA AAGGAATCTA TCAAAAAAGA AGCCTGTTGG 
ACAATCTCTA ATATTACAGC TGGAAATAGG GCACAGATCC AGACTGTGAT AGATGCTAAC 
ATGTTCCCAG CTCTTATTAG TATATTGCAA ACAGCAGAGT TCCGGACAAG GAAGGAAGCT 
GCTTGGGCCA TCACAAATGC AACTTCTGGA GGATCAGCTG AGCAGATCAA GTACCTAGTA 
GAACTGGGTT GTATCAAGCC ACTCTGTGAT CTCCTCACTG TCATGGATGC AAAAATTGTA 
CAGGTTGCCC TAAATGGCTT AGAAAACATC CTGAGGCTTG GAGAACAAGA AGCCAAACGA 
AACGGCTCAG GCATTAATCC TTACTGTGCT TTGATTGAGG AAGCATATGG TCTGGATAAA 
ATTGAGTTCT TACAGAGTCA TGAAAACCAG GAGATCTATC AAAAGGCTTT TGATCTTATT 
GAGCATTACT TTGGGACCGA AGATGAGGAC AGCAGCATCG CACCCCAGGT TGATCTTAGC 
CAGCAGCAGT ACATCTTCCA GCAGTGTGAA GCTCCTATGG AAGGTTTCCA GCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Importin ?1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
PLoS pathogens14(1)e1006823(2018 Jan)
D?hner K,Ramos-Nascimento A,Bialy D,Anderson F,Hickford-Martinez A,Rother F,Koithan T,Rudolph K,Buch A,Prank U,Binz A,H?gel S,Lebbink RJ,Hoeben RC,Hartmann E,Bader M,Bauerfeind R,Sodeik B

The Transcriptional Activator Kr?ppel-like Factor-6 Is Required for CNS Myelination.
PLoS biology14(5)e1002467(2016 May)
Laitman BM,Asp L,Mariani JN,Zhang J,Liu J,Sawai S,Chapouly C,Horng S,Kramer EG,Mitiku N,Loo H,Burlant N,Pedre X,Hara Y,Nudelman G,Zaslavsky E,Lee YM,Braun DA,Lu QR,Narla G,Raine CS,Friedman SL,Casaccia P,John GR

Three distinct classes of the alpha-subunit of the nuclear pore-targeting complex (importin-alpha) are differentially expressed in adult mouse tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society47(3)363-72(1999 Mar)
Kamei Y,Yuba S,Nakayama T,Yoneda Y

Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression.
FEBS letters416(1)30-4(1997 Oct)
Tsuji L,Takumi T,Imamoto N,Yoneda Y

Localization of the importin-beta gene to mouse chromosome 11D and rat chromosome 10q32.1.
Genomics36(1)213-5(1996 Aug)
Matsuda Y,Hamatani K,Itoh M,Takahashi EI,Araki R,Abe M

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Kpna1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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