Klk1b11 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klk1b11
Entrez Gene ID	16613
Full Name	kallikrein 1-related peptidase b11
Synonyms	Klk11,mGK-11
General protein information	Preferred Names kallikrein 1-related peptidase b11 Names kallikrein 1-related peptidase b11 glandular kallikrein K11 tissue kallikrein-11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 B3\|7 28.48 cM
Summary	This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_010640.1	NP_034770.1	kallikrein 1-related peptidase b11 precursor
NM_010640.2	NP_034770.1	kallikrein 1-related peptidase b11 preproprotein

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Klk1b5	NP_032482.1
Mus musculus (house mouse)	Klk1b1	NP_034775.1
Mus musculus (house mouse)	Klk1b3	NP_032719.1
Mus musculus (house mouse)	Klk1b24	NP_034773.1
Mus musculus (house mouse)	Klk1b26	NP_034774.1
Mus musculus (house mouse)	Klk1b4	NP_035045.2
Mus musculus (house mouse)	Klk1b22	NP_034244.1
Mus musculus (house mouse)	Klk1b8	NP_032483.1
Mus musculus (house mouse)	Klk1b21	NP_034772.1
Mus musculus (house mouse)	Klk1b27	NP_064664.1
Homo sapiens (human)	KLK3	NP_001639.1
Mus musculus (house mouse)	Klk1b16	NP_032480.1
Mus musculus (house mouse)	Klk1b11	NP_034770.1
	KLK3	NP_001036241.1
Mus musculus (house mouse)	Klk1	NP_034769.4
Mus musculus (house mouse)	Klk1b9	NP_034246.1

Gene Ontology
Bibliography

Related articles in PubMed

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.
Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM
Biological chemistry387(6)637-41(2006 Jun)

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.
Angata T, Margulies EH, Green ED, Varki A
Proceedings of the National Academy of Sciences of the United States of America101(36)13251-6(2004 Sep)

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Olsson AY, Lilja H, Lundwall A
Genomics84(1)147-56(2004 Jul)

Organization and evolution of the glandular kallikrein locus in Mus musculus.
Olsson AY, Lundwall A
Biochemical and biophysical research communications299(2)305-11(2002 Nov)

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides.
Mason AJ, Evans BA, Cox DR, Shine J, Richards RI
Nature303(5915)300-7(1983 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Klk1b11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klk1b11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06515	NM_010640.2 Latest version!	Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OMu06515	NM_010640.1	Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klk1b11 ( NM_010640.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034770.1 Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.

Price & Availability↑

CloneID	OMu06515
Clone ID Related Accession (Same CDS sequence)	NM_010640.1 , NM_010640.2
Accession Version	NM_010640.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	kallikrein 1-related peptidase b11 precursor
Comment

ATGTGGTTCC TGATCCTGTT CCTAGCCCTG TCCCTAGGAG GGATTGATGC TGCACCTCCT 
GTCCAGTCTC GAATTGTTGG AGGATTTAAC TGTGAGAAGA ATTCCCAACC CTGGCATGTG 
GCTGTGTACC GCTACAACAA ATATATATGC GGGGGAGTCC TGTTGGACCG TAACTGGGTT 
CTCACAGCTG CCCACTGCCA TGTCAGCCAG TATAATGTTT GGCTGGGCAA AACAAAGCTA 
TTCCAACGTG AACCCTCTGC TCAGCACCGA ATGGTCAGCA AAAGCTTCCC CCACCCTGAC 
TACAACATGA GCCTCCTCAT AATCCACAAC CCAGAACCTG AGGACGATGA GAGCAATGAC 
CTGATGTTAC TACGCCTCAG CGAGCCAGCT GACATCACAG ATGCTGTGAA GCCCATCGCC 
CTGCCCACTG AGGAGCCCAA GCTGGGGAGC ACATGCCTAG TCTCAGGCTG GGGCAGCATT 
ACACCCACGA AATTCCAAAC CCCAGATGAT CTCCAGTGTG TGTCCATCAA GCTCCTGCCT 
AATGAGGTCT GTGTCAAAAA CCACAATCAA AAGGTGACAG ATGTCATGTT GTGTGCAGGA 
GAGATGGGTG GAGGCAAAGA TACTTGCAAG GGTGACTCAG GAGGCCCACT GATCTGTGAT 
GGTGTTCTCC ATGGTATCAC AGCATGGGGC CCTATCCCAT GTGGCAAACC CAATACGCCG 
GGAGTCTACA CAAAACTTAT TAAGTTTACC AACTGGATAA AAGACACTAT GGCAAAAAAC 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034770.1
Translation	MWFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWHVAVYRYNKYICGGVLLDRNWVLTAAHCHVSQYNVWLGKTKLFQREPSAQHRMVSKSFPHPDYNMSLLIIHNPEPEDDESNDLMLLRLSEPADITDAVKPIALPTEEPKLGSTCLVSGWGSITPTKFQTPDDLQCVSIKLLPNEVCVKNHNQKVTDVMLCAGEMGGGKDTCKGDSGGPLICDGVLHGITAWGPIPCGKPNTPGVYTKLIKFTNWIKDTMAKNP

Target ORF information:

RefSeq Version	NM_010640.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010640.1

ORF Insert Sequence:

ATGTGGTTCC TGATCCTGTT CCTAGCCCTG TCCCTAGGAG GGATTGATGC TGCACCTCCT 
GTCCAGTCTC GAATTGTTGG AGGATTTAAC TGTGAGAAGA ATTCCCAACC CTGGCATGTG 
GCTGTGTACC GCTACAACAA ATATATATGC GGGGGAGTCC TGTTGGACCG TAACTGGGTT 
CTCACAGCTG CCCACTGCCA TGTCAGCCAG TATAATGTTT GGCTGGGCAA AACAAAGCTA 
TTCCAACGTG AACCCTCTGC TCAGCACCGA ATGGTCAGCA AAAGCTTCCC CCACCCTGAC 
TACAACATGA GCCTCCTCAT AATCCACAAC CCAGAACCTG AGGACGATGA GAGCAATGAC 
CTGATGTTAC TACGCCTCAG CGAGCCAGCT GACATCACAG ATGCTGTGAA GCCCATCGCC 
CTGCCCACTG AGGAGCCCAA GCTGGGGAGC ACATGCCTAG TCTCAGGCTG GGGCAGCATT 
ACACCCACGA AATTCCAAAC CCCAGATGAT CTCCAGTGTG TGTCCATCAA GCTCCTGCCT 
AATGAGGTCT GTGTCAAAAA CCACAATCAA AAGGTGACAG ATGTCATGTT GTGTGCAGGA 
GAGATGGGTG GAGGCAAAGA TACTTGCAAG GGTGACTCAG GAGGCCCACT GATCTGTGAT 
GGTGTTCTCC ATGGTATCAC AGCATGGGGC CCTATCCCAT GTGGCAAACC CAATACGCCG 
GGAGTCTACA CAAAACTTAT TAAGTTTACC AACTGGATAA AAGACACTAT GGCAAAAAAC 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Klk1b11 ( NM_010640.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034770.1 Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.

Price & Availability↑

CloneID	OMu06515
Clone ID Related Accession (Same CDS sequence)	NM_010640.1 , NM_010640.2
Accession Version	NM_010640.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	kallikrein 1-related peptidase b11 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC134858.6. On Feb 24, 2016 this sequence version replaced NM_010640.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC013660.1, BG865922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGTTCC TGATCCTGTT CCTAGCCCTG TCCCTAGGAG GGATTGATGC TGCACCTCCT 
GTCCAGTCTC GAATTGTTGG AGGATTTAAC TGTGAGAAGA ATTCCCAACC CTGGCATGTG 
GCTGTGTACC GCTACAACAA ATATATATGC GGGGGAGTCC TGTTGGACCG TAACTGGGTT 
CTCACAGCTG CCCACTGCCA TGTCAGCCAG TATAATGTTT GGCTGGGCAA AACAAAGCTA 
TTCCAACGTG AACCCTCTGC TCAGCACCGA ATGGTCAGCA AAAGCTTCCC CCACCCTGAC 
TACAACATGA GCCTCCTCAT AATCCACAAC CCAGAACCTG AGGACGATGA GAGCAATGAC 
CTGATGTTAC TACGCCTCAG CGAGCCAGCT GACATCACAG ATGCTGTGAA GCCCATCGCC 
CTGCCCACTG AGGAGCCCAA GCTGGGGAGC ACATGCCTAG TCTCAGGCTG GGGCAGCATT 
ACACCCACGA AATTCCAAAC CCCAGATGAT CTCCAGTGTG TGTCCATCAA GCTCCTGCCT 
AATGAGGTCT GTGTCAAAAA CCACAATCAA AAGGTGACAG ATGTCATGTT GTGTGCAGGA 
GAGATGGGTG GAGGCAAAGA TACTTGCAAG GGTGACTCAG GAGGCCCACT GATCTGTGAT 
GGTGTTCTCC ATGGTATCAC AGCATGGGGC CCTATCCCAT GTGGCAAACC CAATACGCCG 
GGAGTCTACA CAAAACTTAT TAAGTTTACC AACTGGATAA AAGACACTAT GGCAAAAAAC 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034770.1
CDS	29..814
Translation	MWFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWHVAVYRYNKYICGGVLLDRNWVLTAAHCHVSQYNVWLGKTKLFQREPSAQHRMVSKSFPHPDYNMSLLIIHNPEPEDDESNDLMLLRLSEPADITDAVKPIALPTEEPKLGSTCLVSGWGSITPTKFQTPDDLQCVSIKLLPNEVCVKNHNQKVTDVMLCAGEMGGGKDTCKGDSGGPLICDGVLHGITAWGPIPCGKPNTPGVYTKLIKFTNWIKDTMAKNP

Target ORF information:

RefSeq Version	NM_010640.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus kallikrein 1-related peptidase b11 (Klk1b11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010640.2

ORF Insert Sequence:

ATGTGGTTCC TGATCCTGTT CCTAGCCCTG TCCCTAGGAG GGATTGATGC TGCACCTCCT 
GTCCAGTCTC GAATTGTTGG AGGATTTAAC TGTGAGAAGA ATTCCCAACC CTGGCATGTG 
GCTGTGTACC GCTACAACAA ATATATATGC GGGGGAGTCC TGTTGGACCG TAACTGGGTT 
CTCACAGCTG CCCACTGCCA TGTCAGCCAG TATAATGTTT GGCTGGGCAA AACAAAGCTA 
TTCCAACGTG AACCCTCTGC TCAGCACCGA ATGGTCAGCA AAAGCTTCCC CCACCCTGAC 
TACAACATGA GCCTCCTCAT AATCCACAAC CCAGAACCTG AGGACGATGA GAGCAATGAC 
CTGATGTTAC TACGCCTCAG CGAGCCAGCT GACATCACAG ATGCTGTGAA GCCCATCGCC 
CTGCCCACTG AGGAGCCCAA GCTGGGGAGC ACATGCCTAG TCTCAGGCTG GGGCAGCATT 
ACACCCACGA AATTCCAAAC CCCAGATGAT CTCCAGTGTG TGTCCATCAA GCTCCTGCCT 
AATGAGGTCT GTGTCAAAAA CCACAATCAA AAGGTGACAG ATGTCATGTT GTGTGCAGGA 
GAGATGGGTG GAGGCAAAGA TACTTGCAAG GGTGACTCAG GAGGCCCACT GATCTGTGAT 
GGTGTTCTCC ATGGTATCAC AGCATGGGGC CCTATCCCAT GTGGCAAACC CAATACGCCG 
GGAGTCTACA CAAAACTTAT TAAGTTTACC AACTGGATAA AAGACACTAT GGCAAAAAAC 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.
Biological chemistry387(6)637-41(2006 Jun)
Lundwall A,Band V,Blaber M,Clements JA,Courty Y,Diamandis EP,Fritz H,Lilja H,Malm J,Maltais LJ,Olsson AY,Petraki C,Scorilas A,Sotiropoulou G,Stenman UH,Stephan C,Talieri M,Yousef GM

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.
Proceedings of the National Academy of Sciences of the United States of America101(36)13251-6(2004 Sep)
Angata T,Margulies EH,Green ED,Varki A

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Genomics84(1)147-56(2004 Jul)
Olsson AY,Lilja H,Lundwall A

Organization and evolution of the glandular kallikrein locus in Mus musculus.
Biochemical and biophysical research communications299(2)305-11(2002 Nov)
Olsson AY,Lundwall A

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides.
Nature303(5915)300-7(1983 May)
Mason AJ,Evans BA,Cox DR,Shine J,Richards RI

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Klk1b11 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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