Kif3c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kif3c
Entrez Gene ID	16570
Full Name	kinesin family member 3C
Synonyms	mKIAA4058
General protein information	Preferred Names kinesin family member 3C Names kinesin-like protein KIF3C N-4 kinesin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12 A1.1\|12 1.77 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011243817.1	XP_011242119.1	kinesin-like protein KIF3C isoform X1
NM_008445.2	NP_032471.2	kinesin-like protein KIF3C

Pathways from BioSystems

Homologies

	KIF3C	XP_001084972.1
Gallus gallus (chicken)	KIF3C	XP_426988.3
Xenopus tropicalis (tropical clawed frog)	kif3c	XP_002942156.1
Homo sapiens (human)	KIF3C	NP_002245.4
Danio rerio (zebrafish)	kif3cb	NP_001017849.2
Canis lupus familiaris (dog)	KIF3C	XP_540113.2
Bos taurus (cattle)	KIF3C	NP_001071623.1
Rattus norvegicus (Norway rat)	Kif3c	NP_445938.1
Pan troglodytes (chimpanzee)	KIF3C	XP_001149366.1
Mus musculus (house mouse)	Kif3c	NP_032471.2

Gene Ontology
Bibliography

Related articles in PubMed

Homodimeric Kinesin-2 KIF3CC Promotes Microtubule Dynamics.
Guzik-Lendrum S, Rayment I, Gilbert SP
Biophysical journal113(8)1845-1857(2017 Oct)

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.
Albracht CD, Guzik-Lendrum S, Rayment I, Gilbert SP
The Journal of biological chemistry291(44)23248-23256(2016 10)

Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3AC.
Zhang P, Rayment I, Gilbert SP
The Journal of biological chemistry291(9)4407-16(2016 Feb)

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.
Guzik-Lendrum S, Rank KC, Bensel BM, Taylor KC, Rayment I, Gilbert SP
Biophysical journal109(7)1472-82(2015 Oct)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results reveal that engineered homodimeric KIF3CC is targeted to the microtubule plus-end, acts as a potent catastrophe factor through an increase in microtubule catastrophe frequency, and does so by elimination of the dependence of the catastrophe rate on microtubule lifetime. Moreover, KIF3CC accelerates the catastrophe rate without altering the microtubule growth rate.
Title: Homodimeric Kinesin-2 KIF3CC Promotes Microtubule Dynamics.

Data suggest biocatalysis by Kif3a homodimer, Kif3c homodimer, or Kif3a/Kif3c heterodimer vary; microtubule interaction is very fast for Kif3a homodimer; Kif3c homodimer interaction is much slower; Kif3a/Kif3c heterodimer interaction is intermediate.
Title: Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3AC.

Study found that both KIF3AC and KIF3AB can traverse long distances over the microtubule track, revealing that these motors are adept and well-tuned for their specialized roles as cargo transporters
Title: Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.

KIF3C is an injury-specific kinesin that contributes to axon growth and regeneration by regulating and organizing the microtubule cytoskeleton in the growth cone.
Title: The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration.

The following Kif3c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kif3c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01936	NM_008445.2 Latest version!	Mus musculus kinesin family member 3C (Kif3c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OMu01936	XM_011243817.1 Latest version!	Mus musculus kinesin family member 3C (Kif3c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kif3c ( NM_008445.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032471.2 Mus musculus kinesin family member 3C (Kif3c), mRNA.

Price & Availability↑

CloneID	OMu01936
Clone ID Related Accession (Same CDS sequence)	XM_011243817.1 , NM_008445.2
Accession Version	NM_008445.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2391bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	kinesin-like protein KIF3C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK220283.1, AK147572.1, BC062648.1, BQ175623.1 and AW125727.1. On Jan 11, 2006 this sequence version replaced NM_008445.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147572.1, SRR1660815.249559.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAGTA AGACCAAGGC CAGCGAGGCC CTGAAGGTGG TGGCCCGGTG CCGCCCCCTC 
AGTAGGAAGG AGGAGGCTGC TGGTCATGAG CAGATTCTGA CCATGGACGT GAAACTGGGC 
CAGGTGACTC TGCGAAACCC CCGCGCGGCA CCCGGGGAGC TGCCCAAGAC CTTCACTTTT 
GATGCTGTGT ATGATGCTAG CTCCAAGCAG GCCGACCTGT ATGACGAAAC GGTGAGGCCC 
CTGATAGACT CAGTGCTTCA GGGTTTCAAC GGCACCGTAT TTGCCTATGG CCAGACTGGC 
ACTGGCAAGA CCTACACCAT GCAGGGGACC TGGGTGGAGC CAGAGCTCCG CGGGGTTATC 
CCGAATGCCT TTGAGCACAT CTTCACCCAC ATCTCCCGCT CCCAGAACCA GCAGTACCTG 
GTTCGTGCTT CCTACTTGGA GATCTACCAG GAGGAGATCC GAGACCTGCT ATCCAAGGAG 
CCAGGCAAGA GGCTAGAGCT GAAGGAGAAT CCTGAAACAG GGGTCTACAT CAAGGACCTC 
TCTTCCTTTG TCACCAAGAA TGTCAAGGAG ATTGAGCATG TGATGAACCT GGGGAACCAA 
GCCCGAGCAG TGGGCAGCAC CCACATGAAT GAGGTCAGCT CTCGGTCCCA TGCCATCTTT 
GTTATCACAG TGGAGTGCAG TGAGCGTGGC TCTGATGGCC AGGATCATAT CCGAGTAGGC 
AAGCTCAACC TGGTAGACCT GGCCGGCAGT GAGAGACAGA ACAAGGCTGG TCCCAACGCA 
GCTGGAGGGC CAGCCACACA GCCAACAGCT GGTGGTGGGA GTGGAAGTGG CAGCGCTAGT 
GGTTCTGCCA GCAGCGGAGA GAGGCCTAAG GAAGCTTCTA AAATCAATCT CTCGCTGTCC 
GCCCTGGGCA ATGTGATTGC TGCTCTGGCT GGCAACAGGA GCACCCACAT CCCCTACCGG 
GACTCCAAGC TAACCCGGCT GCTCCAAGAC TCACTGGGGG GCAATGCCAA GACCATCATG 
GTGGCCACAC TGGGTCCAGC TTCTCACAGC TACGACGAGA GCCTCTCTAC CCTGCGCTTT 
GCCAACCGAG CCAAGAACAT CAAGAACAAA CCGCGGGTGA ACGAGGACCC CAAGGACACA 
CTGCTGAGGG AATTCCAGGA AGAGATCGCT CGCTTGAAGG CCCAGCTGGA GAAGAAGGGG 
ATGCTGGGCA AGCGACCTCG GAGAAAGAGC AGTCGTAGAA AGAAGGCCGT GTCTGCCCCA 
GCCGGCTATC CAGAGGGGTC CGTGATTGAG GCCTGGGTGG CCGAAGAGGA AGATGATAAC 
AACAACAATC ACCACCCACC CCAGCCCATC TTGGAGGCAG CTTTGGAGAA GAACATGGAG 
AATTACCTGC AGGACCAGAA GGAACGGCTG GAGGAGGAGA AGGCTGCCAT CCAGGATGAC 
CGCAGCCTTG TGAGTGAGGA GAAGCAGAAG CTTCTAGAAG AGAAGGAGAA GATGCTGGAG 
GATCTACGGC GGGAGCAGCA GGCTACAGAG CTGCTTGCAG CCAAGTACAA GGCCATGGAA 
AGCAAGCTAC TCATTGGGGG GCGGAACATC ATGGATCACA CCAACGAGCA ACAGAAGATG 
TTGGAACTGA AGCGACAGGA GATTGCGGAA CAGAAACGCC GTGAACGGGA AATGCAGCAG 
GAGATGCTGC TCCGCGATGA AGAAACCATG GAGCTACGTG GTACCTACTC ATCCCTGCAG 
CAGGAGGTGG AAGTTAAAAC CAAGAAACTC AAGAAGCTCT ATGCCAAGCT ACAGGCGGTG 
AAGGCCGAGA TCCAGGACCA ACACGAAGAG TACATCCGCG TGCGGCAGGA CCTGGAGGAG 
GCGCAGAATG AGCAGACCCG GGAACTAAAG CTCAAGTACC TCATCATTGA GAACTTCATC 
CCCCCTGAGG AGAAGAACAA GATCATGAAC CGCCTTTTCC TGGACTGTGA GGAGGAGCAG 
TGGAGGTTCC AGCCACTGGT GCCAGCTGGA GTGAATAACA GCCAAATGAA GAAGCGTCCA 
ACTTCTGCGG TGGGCTACAA GAGACCTATC AGCCAGTATG CTCGGGTTGC CATGGCAATG 
GGGTCCCATC CCAGATACAG AGCTGAAAAT ATAATGTTTT TGGAACTGGA TGTGTCCCCA 
CCGGCTATCT TTGAGATGGA GTTTTCTCAT GACCAAGAGC AAGACCCACG GGTACTACAC 
ATGGAGAGGC TCATGAGGTT GGACAGCTTT CTGGAAAGAC CGTCCACAAC TAAAGTGCGA 
AAGTCGAGAT CCTGGTGCCA GAGTCCTCAG CGGATGCCTC CACCCTCCAC AGCTCATGCA 
TCCATGACCT CTGTTCCTTT GCACCCTGCA ACAGTGGTAG ACCATGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032471.2
CDS	850..3240
Translation	MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNAAGGPATQPTAGGGSGSGSASGSASSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGSVIEAWVAEEEDDNNNNHHPPQPILEAALEKNMENYLQDQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWRFQPLVPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAIFEMEFSHDQEQDPRVLHMERLMRLDSFLERPSTTKVRKSRSWCQSPQRMPPPSTAHASMTSVPLHPATVVDHD

Target ORF information:

RefSeq Version	NM_008445.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus kinesin family member 3C (Kif3c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008445.2

ORF Insert Sequence:

ATGGCCAGTA AGACCAAGGC CAGCGAGGCC CTGAAGGTGG TGGCCCGGTG CCGCCCCCTC 
AGTAGGAAGG AGGAGGCTGC TGGTCATGAG CAGATTCTGA CCATGGACGT GAAACTGGGC 
CAGGTGACTC TGCGAAACCC CCGCGCGGCA CCCGGGGAGC TGCCCAAGAC CTTCACTTTT 
GATGCTGTGT ATGATGCTAG CTCCAAGCAG GCCGACCTGT ATGACGAAAC GGTGAGGCCC 
CTGATAGACT CAGTGCTTCA GGGTTTCAAC GGCACCGTAT TTGCCTATGG CCAGACTGGC 
ACTGGCAAGA CCTACACCAT GCAGGGGACC TGGGTGGAGC CAGAGCTCCG CGGGGTTATC 
CCGAATGCCT TTGAGCACAT CTTCACCCAC ATCTCCCGCT CCCAGAACCA GCAGTACCTG 
GTTCGTGCTT CCTACTTGGA GATCTACCAG GAGGAGATCC GAGACCTGCT ATCCAAGGAG 
CCAGGCAAGA GGCTAGAGCT GAAGGAGAAT CCTGAAACAG GGGTCTACAT CAAGGACCTC 
TCTTCCTTTG TCACCAAGAA TGTCAAGGAG ATTGAGCATG TGATGAACCT GGGGAACCAA 
GCCCGAGCAG TGGGCAGCAC CCACATGAAT GAGGTCAGCT CTCGGTCCCA TGCCATCTTT 
GTTATCACAG TGGAGTGCAG TGAGCGTGGC TCTGATGGCC AGGATCATAT CCGAGTAGGC 
AAGCTCAACC TGGTAGACCT GGCCGGCAGT GAGAGACAGA ACAAGGCTGG TCCCAACGCA 
GCTGGAGGGC CAGCCACACA GCCAACAGCT GGTGGTGGGA GTGGAAGTGG CAGCGCTAGT 
GGTTCTGCCA GCAGCGGAGA GAGGCCTAAG GAAGCTTCTA AAATCAATCT CTCGCTGTCC 
GCCCTGGGCA ATGTGATTGC TGCTCTGGCT GGCAACAGGA GCACCCACAT CCCCTACCGG 
GACTCCAAGC TAACCCGGCT GCTCCAAGAC TCACTGGGGG GCAATGCCAA GACCATCATG 
GTGGCCACAC TGGGTCCAGC TTCTCACAGC TACGACGAGA GCCTCTCTAC CCTGCGCTTT 
GCCAACCGAG CCAAGAACAT CAAGAACAAA CCGCGGGTGA ACGAGGACCC CAAGGACACA 
CTGCTGAGGG AATTCCAGGA AGAGATCGCT CGCTTGAAGG CCCAGCTGGA GAAGAAGGGG 
ATGCTGGGCA AGCGACCTCG GAGAAAGAGC AGTCGTAGAA AGAAGGCCGT GTCTGCCCCA 
GCCGGCTATC CAGAGGGGTC CGTGATTGAG GCCTGGGTGG CCGAAGAGGA AGATGATAAC 
AACAACAATC ACCACCCACC CCAGCCCATC TTGGAGGCAG CTTTGGAGAA GAACATGGAG 
AATTACCTGC AGGACCAGAA GGAACGGCTG GAGGAGGAGA AGGCTGCCAT CCAGGATGAC 
CGCAGCCTTG TGAGTGAGGA GAAGCAGAAG CTTCTAGAAG AGAAGGAGAA GATGCTGGAG 
GATCTACGGC GGGAGCAGCA GGCTACAGAG CTGCTTGCAG CCAAGTACAA GGCCATGGAA 
AGCAAGCTAC TCATTGGGGG GCGGAACATC ATGGATCACA CCAACGAGCA ACAGAAGATG 
TTGGAACTGA AGCGACAGGA GATTGCGGAA CAGAAACGCC GTGAACGGGA AATGCAGCAG 
GAGATGCTGC TCCGCGATGA AGAAACCATG GAGCTACGTG GTACCTACTC ATCCCTGCAG 
CAGGAGGTGG AAGTTAAAAC CAAGAAACTC AAGAAGCTCT ATGCCAAGCT ACAGGCGGTG 
AAGGCCGAGA TCCAGGACCA ACACGAAGAG TACATCCGCG TGCGGCAGGA CCTGGAGGAG 
GCGCAGAATG AGCAGACCCG GGAACTAAAG CTCAAGTACC TCATCATTGA GAACTTCATC 
CCCCCTGAGG AGAAGAACAA GATCATGAAC CGCCTTTTCC TGGACTGTGA GGAGGAGCAG 
TGGAGGTTCC AGCCACTGGT GCCAGCTGGA GTGAATAACA GCCAAATGAA GAAGCGTCCA 
ACTTCTGCGG TGGGCTACAA GAGACCTATC AGCCAGTATG CTCGGGTTGC CATGGCAATG 
GGGTCCCATC CCAGATACAG AGCTGAAAAT ATAATGTTTT TGGAACTGGA TGTGTCCCCA 
CCGGCTATCT TTGAGATGGA GTTTTCTCAT GACCAAGAGC AAGACCCACG GGTACTACAC 
ATGGAGAGGC TCATGAGGTT GGACAGCTTT CTGGAAAGAC CGTCCACAAC TAAAGTGCGA 
AAGTCGAGAT CCTGGTGCCA GAGTCCTCAG CGGATGCCTC CACCCTCCAC AGCTCATGCA 
TCCATGACCT CTGTTCCTTT GCACCCTGCA ACAGTGGTAG ACCATGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kif3c ( XM_011243817.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242119.1 Mus musculus kinesin family member 3C (Kif3c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01936
Clone ID Related Accession (Same CDS sequence)	XM_011243817.1 , NM_008445.2
Accession Version	XM_011243817.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2391bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	kinesin-like protein KIF3C isoform X1
Comment

ATGGCCAGTA AGACCAAGGC CAGCGAGGCC CTGAAGGTGG TGGCCCGGTG CCGCCCCCTC 
AGTAGGAAGG AGGAGGCTGC TGGTCATGAG CAGATTCTGA CCATGGACGT GAAACTGGGC 
CAGGTGACTC TGCGAAACCC CCGCGCGGCA CCCGGGGAGC TGCCCAAGAC CTTCACTTTT 
GATGCTGTGT ATGATGCTAG CTCCAAGCAG GCCGACCTGT ATGACGAAAC GGTGAGGCCC 
CTGATAGACT CAGTGCTTCA GGGTTTCAAC GGCACCGTAT TTGCCTATGG CCAGACTGGC 
ACTGGCAAGA CCTACACCAT GCAGGGGACC TGGGTGGAGC CAGAGCTCCG CGGGGTTATC 
CCGAATGCCT TTGAGCACAT CTTCACCCAC ATCTCCCGCT CCCAGAACCA GCAGTACCTG 
GTTCGTGCTT CCTACTTGGA GATCTACCAG GAGGAGATCC GAGACCTGCT ATCCAAGGAG 
CCAGGCAAGA GGCTAGAGCT GAAGGAGAAT CCTGAAACAG GGGTCTACAT CAAGGACCTC 
TCTTCCTTTG TCACCAAGAA TGTCAAGGAG ATTGAGCATG TGATGAACCT GGGGAACCAA 
GCCCGAGCAG TGGGCAGCAC CCACATGAAT GAGGTCAGCT CTCGGTCCCA TGCCATCTTT 
GTTATCACAG TGGAGTGCAG TGAGCGTGGC TCTGATGGCC AGGATCATAT CCGAGTAGGC 
AAGCTCAACC TGGTAGACCT GGCCGGCAGT GAGAGACAGA ACAAGGCTGG TCCCAACGCA 
GCTGGAGGGC CAGCCACACA GCCAACAGCT GGTGGTGGGA GTGGAAGTGG CAGCGCTAGT 
GGTTCTGCCA GCAGCGGAGA GAGGCCTAAG GAAGCTTCTA AAATCAATCT CTCGCTGTCC 
GCCCTGGGCA ATGTGATTGC TGCTCTGGCT GGCAACAGGA GCACCCACAT CCCCTACCGG 
GACTCCAAGC TAACCCGGCT GCTCCAAGAC TCACTGGGGG GCAATGCCAA GACCATCATG 
GTGGCCACAC TGGGTCCAGC TTCTCACAGC TACGACGAGA GCCTCTCTAC CCTGCGCTTT 
GCCAACCGAG CCAAGAACAT CAAGAACAAA CCGCGGGTGA ACGAGGACCC CAAGGACACA 
CTGCTGAGGG AATTCCAGGA AGAGATCGCT CGCTTGAAGG CCCAGCTGGA GAAGAAGGGG 
ATGCTGGGCA AGCGACCTCG GAGAAAGAGC AGTCGTAGAA AGAAGGCCGT GTCTGCCCCA 
GCCGGCTATC CAGAGGGGTC CGTGATTGAG GCCTGGGTGG CCGAAGAGGA AGATGATAAC 
AACAACAATC ACCACCCACC CCAGCCCATC TTGGAGGCAG CTTTGGAGAA GAACATGGAG 
AATTACCTGC AGGACCAGAA GGAACGGCTG GAGGAGGAGA AGGCTGCCAT CCAGGATGAC 
CGCAGCCTTG TGAGTGAGGA GAAGCAGAAG CTTCTAGAAG AGAAGGAGAA GATGCTGGAG 
GATCTACGGC GGGAGCAGCA GGCTACAGAG CTGCTTGCAG CCAAGTACAA GGCCATGGAA 
AGCAAGCTAC TCATTGGGGG GCGGAACATC ATGGATCACA CCAACGAGCA ACAGAAGATG 
TTGGAACTGA AGCGACAGGA GATTGCGGAA CAGAAACGCC GTGAACGGGA AATGCAGCAG 
GAGATGCTGC TCCGCGATGA AGAAACCATG GAGCTACGTG GTACCTACTC ATCCCTGCAG 
CAGGAGGTGG AAGTTAAAAC CAAGAAACTC AAGAAGCTCT ATGCCAAGCT ACAGGCGGTG 
AAGGCCGAGA TCCAGGACCA ACACGAAGAG TACATCCGCG TGCGGCAGGA CCTGGAGGAG 
GCGCAGAATG AGCAGACCCG GGAACTAAAG CTCAAGTACC TCATCATTGA GAACTTCATC 
CCCCCTGAGG AGAAGAACAA GATCATGAAC CGCCTTTTCC TGGACTGTGA GGAGGAGCAG 
TGGAGGTTCC AGCCACTGGT GCCAGCTGGA GTGAATAACA GCCAAATGAA GAAGCGTCCA 
ACTTCTGCGG TGGGCTACAA GAGACCTATC AGCCAGTATG CTCGGGTTGC CATGGCAATG 
GGGTCCCATC CCAGATACAG AGCTGAAAAT ATAATGTTTT TGGAACTGGA TGTGTCCCCA 
CCGGCTATCT TTGAGATGGA GTTTTCTCAT GACCAAGAGC AAGACCCACG GGTACTACAC 
ATGGAGAGGC TCATGAGGTT GGACAGCTTT CTGGAAAGAC CGTCCACAAC TAAAGTGCGA 
AAGTCGAGAT CCTGGTGCCA GAGTCCTCAG CGGATGCCTC CACCCTCCAC AGCTCATGCA 
TCCATGACCT CTGTTCCTTT GCACCCTGCA ACAGTGGTAG ACCATGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011242119.1

Translation

MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNAAGGPATQPTAGGGSGSGSASGSASSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGSVIEAWVAEEEDDNNNNHHPPQPILEAALEKNMENYLQDQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWRFQPLVPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAIFEMEFSHDQEQDPRVLHMERLMRLDSFLERPSTTKVRKSRSWCQSPQRMPPPSTAHASMTSVPLHPATVVDHD

Target ORF information:

RefSeq Version	XM_011243817.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus kinesin family member 3C (Kif3c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243817.1

ORF Insert Sequence:

ATGGCCAGTA AGACCAAGGC CAGCGAGGCC CTGAAGGTGG TGGCCCGGTG CCGCCCCCTC 
AGTAGGAAGG AGGAGGCTGC TGGTCATGAG CAGATTCTGA CCATGGACGT GAAACTGGGC 
CAGGTGACTC TGCGAAACCC CCGCGCGGCA CCCGGGGAGC TGCCCAAGAC CTTCACTTTT 
GATGCTGTGT ATGATGCTAG CTCCAAGCAG GCCGACCTGT ATGACGAAAC GGTGAGGCCC 
CTGATAGACT CAGTGCTTCA GGGTTTCAAC GGCACCGTAT TTGCCTATGG CCAGACTGGC 
ACTGGCAAGA CCTACACCAT GCAGGGGACC TGGGTGGAGC CAGAGCTCCG CGGGGTTATC 
CCGAATGCCT TTGAGCACAT CTTCACCCAC ATCTCCCGCT CCCAGAACCA GCAGTACCTG 
GTTCGTGCTT CCTACTTGGA GATCTACCAG GAGGAGATCC GAGACCTGCT ATCCAAGGAG 
CCAGGCAAGA GGCTAGAGCT GAAGGAGAAT CCTGAAACAG GGGTCTACAT CAAGGACCTC 
TCTTCCTTTG TCACCAAGAA TGTCAAGGAG ATTGAGCATG TGATGAACCT GGGGAACCAA 
GCCCGAGCAG TGGGCAGCAC CCACATGAAT GAGGTCAGCT CTCGGTCCCA TGCCATCTTT 
GTTATCACAG TGGAGTGCAG TGAGCGTGGC TCTGATGGCC AGGATCATAT CCGAGTAGGC 
AAGCTCAACC TGGTAGACCT GGCCGGCAGT GAGAGACAGA ACAAGGCTGG TCCCAACGCA 
GCTGGAGGGC CAGCCACACA GCCAACAGCT GGTGGTGGGA GTGGAAGTGG CAGCGCTAGT 
GGTTCTGCCA GCAGCGGAGA GAGGCCTAAG GAAGCTTCTA AAATCAATCT CTCGCTGTCC 
GCCCTGGGCA ATGTGATTGC TGCTCTGGCT GGCAACAGGA GCACCCACAT CCCCTACCGG 
GACTCCAAGC TAACCCGGCT GCTCCAAGAC TCACTGGGGG GCAATGCCAA GACCATCATG 
GTGGCCACAC TGGGTCCAGC TTCTCACAGC TACGACGAGA GCCTCTCTAC CCTGCGCTTT 
GCCAACCGAG CCAAGAACAT CAAGAACAAA CCGCGGGTGA ACGAGGACCC CAAGGACACA 
CTGCTGAGGG AATTCCAGGA AGAGATCGCT CGCTTGAAGG CCCAGCTGGA GAAGAAGGGG 
ATGCTGGGCA AGCGACCTCG GAGAAAGAGC AGTCGTAGAA AGAAGGCCGT GTCTGCCCCA 
GCCGGCTATC CAGAGGGGTC CGTGATTGAG GCCTGGGTGG CCGAAGAGGA AGATGATAAC 
AACAACAATC ACCACCCACC CCAGCCCATC TTGGAGGCAG CTTTGGAGAA GAACATGGAG 
AATTACCTGC AGGACCAGAA GGAACGGCTG GAGGAGGAGA AGGCTGCCAT CCAGGATGAC 
CGCAGCCTTG TGAGTGAGGA GAAGCAGAAG CTTCTAGAAG AGAAGGAGAA GATGCTGGAG 
GATCTACGGC GGGAGCAGCA GGCTACAGAG CTGCTTGCAG CCAAGTACAA GGCCATGGAA 
AGCAAGCTAC TCATTGGGGG GCGGAACATC ATGGATCACA CCAACGAGCA ACAGAAGATG 
TTGGAACTGA AGCGACAGGA GATTGCGGAA CAGAAACGCC GTGAACGGGA AATGCAGCAG 
GAGATGCTGC TCCGCGATGA AGAAACCATG GAGCTACGTG GTACCTACTC ATCCCTGCAG 
CAGGAGGTGG AAGTTAAAAC CAAGAAACTC AAGAAGCTCT ATGCCAAGCT ACAGGCGGTG 
AAGGCCGAGA TCCAGGACCA ACACGAAGAG TACATCCGCG TGCGGCAGGA CCTGGAGGAG 
GCGCAGAATG AGCAGACCCG GGAACTAAAG CTCAAGTACC TCATCATTGA GAACTTCATC 
CCCCCTGAGG AGAAGAACAA GATCATGAAC CGCCTTTTCC TGGACTGTGA GGAGGAGCAG 
TGGAGGTTCC AGCCACTGGT GCCAGCTGGA GTGAATAACA GCCAAATGAA GAAGCGTCCA 
ACTTCTGCGG TGGGCTACAA GAGACCTATC AGCCAGTATG CTCGGGTTGC CATGGCAATG 
GGGTCCCATC CCAGATACAG AGCTGAAAAT ATAATGTTTT TGGAACTGGA TGTGTCCCCA 
CCGGCTATCT TTGAGATGGA GTTTTCTCAT GACCAAGAGC AAGACCCACG GGTACTACAC 
ATGGAGAGGC TCATGAGGTT GGACAGCTTT CTGGAAAGAC CGTCCACAAC TAAAGTGCGA 
AAGTCGAGAT CCTGGTGCCA GAGTCCTCAG CGGATGCCTC CACCCTCCAC AGCTCATGCA 
TCCATGACCT CTGTTCCTTT GCACCCTGCA ACAGTGGTAG ACCATGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Homodimeric Kinesin-2 KIF3CC Promotes Microtubule Dynamics.
Biophysical journal113(8)1845-1857(2017 Oct)
Guzik-Lendrum S,Rayment I,Gilbert SP

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.
The Journal of biological chemistry291(44)23248-23256(2016 10)
Albracht CD,Guzik-Lendrum S,Rayment I,Gilbert SP

Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3AC.
The Journal of biological chemistry291(9)4407-16(2016 Feb)
Zhang P,Rayment I,Gilbert SP

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.
Biophysical journal109(7)1472-82(2015 Oct)
Guzik-Lendrum S,Rank KC,Bensel BM,Taylor KC,Rayment I,Gilbert SP

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

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Kif3c cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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