Napsa cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Napsa
Entrez Gene ID	16541
Full Name	napsin A aspartic peptidase
Synonyms	KAP,Kdap,NAP1,SNAPA,pronapsin
General protein information	Preferred Names napsin A aspartic peptidase Names napsin-A KDAP-1 kidney-derived aspartic protease-like protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_008437.1	NP_032463.1	napsin-A precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NAPSA	XP_533610.2
Mus musculus (house mouse)	Napsa	NP_032463.1
Pan troglodytes (chimpanzee)	NAPSA	XP_524345.2
Bos taurus (cattle)	NAPSA	XP_002695173.1
Rattus norvegicus (Norway rat)	Napsa	NP_113858.1
Homo sapiens (human)	NAPSA	NP_004842.1
	NAPSA	XP_001116026.1

Gene Ontology
Bibliography

Related articles in PubMed

Lymphatic function is required prenatally for lung inflation at birth.
Jakus Z, Gleghorn JP, Enis DR, Sen A, Chia S, Liu X, Rawnsley DR, Yang Y, Hess PR, Zou Z, Yang J, Guttentag SH, Nelson CM, Kahn ML
The Journal of experimental medicine211(5)815-26(2014 May)

Lung epithelial branching program antagonizes alveolar differentiation.
Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J
Proceedings of the National Academy of Sciences of the United States of America110(45)18042-51(2013 Nov)

Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-? production and antiviral response by targeting NAP1.
Zhao W, Wang L, Zhang M, Wang P, Yuan C, Qi J, Meng H, Gao C
Journal of immunology (Baltimore, Md. : 1950)188(11)5311-8(2012 Jun)

Transcriptional programs controlling perinatal lung maturation.
Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA
PloS one7(8)e37046(2012)

Maternal synchronization of gestational length and lung maturation.
Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA
PloS one6(11)e26682(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Napsa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Napsa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22387	NM_008437.1 Latest version!	Mus musculus napsin A aspartic peptidase (Napsa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Napsa ( NM_008437.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032463.1 Mus musculus napsin A aspartic peptidase (Napsa), mRNA.

Price & Availability↑

CloneID	OMu22387
Clone ID Related Accession (Same CDS sequence)	NM_008437.1
Accession Version	NM_008437.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	napsin-A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from D88899.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D88899.1, AB038144.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCGCCAC TACTGCTGCT GCTGCTGTGC CTGCTGCTGG GGAATTTGGA GCCTGAGGAG 
GCCAAACTGA TCCGTGTCCC TCTTCAACGA ATCCACCTTG GACACAGAAT CTTAAACCCA 
CTGAATGGAT GGGAACAGCT GGCAGAGCTT TCTAGGACCT CCACCTCTGG TGGCAACCCC 
TCCTTTGTGC CTCTCTCCAA GTTCATGAAC ACCCAGTATT TTGGAACTAT TGGTTTGGGA 
ACGCCTCCTC AGAATTTCAC CGTTGTCTTT GACACGGGTT CTTCCAACTT GTGGGTTCCG 
TCCACGAGAT GTCATTTCTT CAGTTTGGCA TGCTGGTTTC ACCATCGCTT TAATCCCAAG 
GCCTCCAGCT CCTTCAGGCC CAATGGGACC AAGTTTGCCA TTCAGTATGG GACCGGGCGG 
CTGAGCGGAA TCCTGAGCCA GGACAATCTG ACTATCGGGG GGATCCACGA TGCTTTTGTG 
ACATTTGGAG AGGCTCTGTG GGAGCCCAGC CTGATCTTTG CTTTAGCCCA CTTTGATGGG 
ATCCTGGGCC TCGGCTTCCC CACTCTGGCT GTGGGCGGAG TTCAGCCTCC GCTGGATGCG 
ATGGTGGAGC AAGGGCTGCT GGAGAAACCC GTCTTCTCCT TTTACCTCAA CAGGGATTCT 
GAAGGGTCTG ATGGGGGAGA GCTGGTCCTA GGGGGCTCAG ACCCCGCTCA CTACGTACCT 
CCCCTCACCT TCATACCAGT CACCATCCCT GCCTACTGGC AGGTCCACAT GGAGAGTGTG 
AAGGTCGGCA CAGGGCTGAG CCTCTGTGCC CAGGGCTGCA GTGCCATCCT AGACACAGGC 
ACATCCCTCA TCACAGGACC TAGTGAGGAG ATCCGGGCCT TGAATAAAGC CATTGGGGGA 
TATCCCTTCC TGAATGGGCA GTACTTCATT CAGTGTTCCA AGACGCCAAC GCTTCCCCCT 
GTCTCCTTCC ACCTTGGTGG AGTCTGGTTT AACCTCACAG GCCAGGACTA TGTCATCAAG 
ATTCTTCAGA GCGATGTTGG CCTCTGCCTG TTGGGCTTCC AAGCCTTGGA TATCCCCAAG 
CCTGCGGGAC CCCTCTGGAT CCTTGGGGAC GTCTTTTTGG GGCCCTATGT GGCTGTCTTT 
GACCGTGGGG ACAAAAACGT CGGCCCGCGC GTGGGACTGG CGCGTGCTCA GTCTCGTTCA 
ACAGACCGGG CAGAAAGAAG GACTACGCAG GCGCAGTTCT TCAAAAGACG CCCTGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032463.1
CDS	172..1431
Translation	MSPLLLLLLCLLLGNLEPEEAKLIRVPLQRIHLGHRILNPLNGWEQLAELSRTSTSGGNPSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSFRPNGTKFAIQYGTGRLSGILSQDNLTIGGIHDAFVTFGEALWEPSLIFALAHFDGILGLGFPTLAVGGVQPPLDAMVEQGLLEKPVFSFYLNRDSEGSDGGELVLGGSDPAHYVPPLTFIPVTIPAYWQVHMESVKVGTGLSLCAQGCSAILDTGTSLITGPSEEIRALNKAIGGYPFLNGQYFIQCSKTPTLPPVSFHLGGVWFNLTGQDYVIKILQSDVGLCLLGFQALDIPKPAGPLWILGDVFLGPYVAVFDRGDKNVGPRVGLARAQSRSTDRAERRTTQAQFFKRRPG

Target ORF information:

RefSeq Version	NM_008437.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus napsin A aspartic peptidase (Napsa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008437.1

ORF Insert Sequence:

ATGTCGCCAC TACTGCTGCT GCTGCTGTGC CTGCTGCTGG GGAATTTGGA GCCTGAGGAG 
GCCAAACTGA TCCGTGTCCC TCTTCAACGA ATCCACCTTG GACACAGAAT CTTAAACCCA 
CTGAATGGAT GGGAACAGCT GGCAGAGCTT TCTAGGACCT CCACCTCTGG TGGCAACCCC 
TCCTTTGTGC CTCTCTCCAA GTTCATGAAC ACCCAGTATT TTGGAACTAT TGGTTTGGGA 
ACGCCTCCTC AGAATTTCAC CGTTGTCTTT GACACGGGTT CTTCCAACTT GTGGGTTCCG 
TCCACGAGAT GTCATTTCTT CAGTTTGGCA TGCTGGTTTC ACCATCGCTT TAATCCCAAG 
GCCTCCAGCT CCTTCAGGCC CAATGGGACC AAGTTTGCCA TTCAGTATGG GACCGGGCGG 
CTGAGCGGAA TCCTGAGCCA GGACAATCTG ACTATCGGGG GGATCCACGA TGCTTTTGTG 
ACATTTGGAG AGGCTCTGTG GGAGCCCAGC CTGATCTTTG CTTTAGCCCA CTTTGATGGG 
ATCCTGGGCC TCGGCTTCCC CACTCTGGCT GTGGGCGGAG TTCAGCCTCC GCTGGATGCG 
ATGGTGGAGC AAGGGCTGCT GGAGAAACCC GTCTTCTCCT TTTACCTCAA CAGGGATTCT 
GAAGGGTCTG ATGGGGGAGA GCTGGTCCTA GGGGGCTCAG ACCCCGCTCA CTACGTACCT 
CCCCTCACCT TCATACCAGT CACCATCCCT GCCTACTGGC AGGTCCACAT GGAGAGTGTG 
AAGGTCGGCA CAGGGCTGAG CCTCTGTGCC CAGGGCTGCA GTGCCATCCT AGACACAGGC 
ACATCCCTCA TCACAGGACC TAGTGAGGAG ATCCGGGCCT TGAATAAAGC CATTGGGGGA 
TATCCCTTCC TGAATGGGCA GTACTTCATT CAGTGTTCCA AGACGCCAAC GCTTCCCCCT 
GTCTCCTTCC ACCTTGGTGG AGTCTGGTTT AACCTCACAG GCCAGGACTA TGTCATCAAG 
ATTCTTCAGA GCGATGTTGG CCTCTGCCTG TTGGGCTTCC AAGCCTTGGA TATCCCCAAG 
CCTGCGGGAC CCCTCTGGAT CCTTGGGGAC GTCTTTTTGG GGCCCTATGT GGCTGTCTTT 
GACCGTGGGG ACAAAAACGT CGGCCCGCGC GTGGGACTGG CGCGTGCTCA GTCTCGTTCA 
ACAGACCGGG CAGAAAGAAG GACTACGCAG GCGCAGTTCT TCAAAAGACG CCCTGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lymphatic function is required prenatally for lung inflation at birth.
The Journal of experimental medicine211(5)815-26(2014 May)
Jakus Z,Gleghorn JP,Enis DR,Sen A,Chia S,Liu X,Rawnsley DR,Yang Y,Hess PR,Zou Z,Yang J,Guttentag SH,Nelson CM,Kahn ML

Lung epithelial branching program antagonizes alveolar differentiation.
Proceedings of the National Academy of Sciences of the United States of America110(45)18042-51(2013 Nov)
Chang DR,Martinez Alanis D,Miller RK,Ji H,Akiyama H,McCrea PD,Chen J

Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-? production and antiviral response by targeting NAP1.
Journal of immunology (Baltimore, Md. : 1950)188(11)5311-8(2012 Jun)
Zhao W,Wang L,Zhang M,Wang P,Yuan C,Qi J,Meng H,Gao C

Transcriptional programs controlling perinatal lung maturation.
PloS one7(8)e37046(2012)
Xu Y,Wang Y,Besnard V,Ikegami M,Wert SE,Heffner C,Murray SA,Donahue LR,Whitsett JA

Maternal synchronization of gestational length and lung maturation.
PloS one6(11)e26682(2011)
Besnard V,Wert SE,Ikegami M,Xu Y,Heffner C,Murray SA,Donahue LR,Whitsett JA

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Napsa cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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