Itgav cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itgav
Entrez Gene ID	16410
Full Name	integrin alpha V
Synonyms	1110004F14Rik,2610028E01Rik,CD51,D430040G12Rik
General protein information	Preferred Names integrin alpha V Names integrin alpha-V alpha v integrin vitronectin receptor alpha polypeptide (VNRA) vitronectin receptor subunit alpha
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 D\|2 49.33 cM
Summary	This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 1, beta 3, beta 6 and beta 8. The heterodimer of alpha v and beta 3 forms the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. In mouse, deficiency of this gene is associated with defects in vascular morphogenesis in the brain and early post-natal death. [provided by RefSeq, May 2013].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006498807.3	XP_006498870.1	integrin alpha-V isoform X1
XM_006498807.4	XP_006498870.1	integrin alpha-V isoform X1
NM_008402.3	NP_032428.2	integrin alpha-V precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ITGAV	NP_002201.1
	ITGAV	XP_001104012.1
Canis lupus familiaris (dog)	ITGAV	XP_850989.2
Bos taurus (cattle)	ITGAV	NP_776792.1
Danio rerio (zebrafish)	itgav	NP_001028893.1
Rattus norvegicus (Norway rat)	Itgav	XP_006234499.1
Gallus gallus (chicken)	ITGAV	NP_990770.1
Mus musculus (house mouse)	Itgav	NP_032428.2
Pan troglodytes (chimpanzee)	ITGAV	XP_515967.3
Xenopus tropicalis (tropical clawed frog)	itgav	NP_001116921.1

Gene Ontology
Bibliography

Related articles in PubMed

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.
Bader BL, Rayburn H, Crowley D, Hynes RO
Cell95(4)507-19(1998 Nov)

Characterization of the integrin alpha(v) gene promoter in mice.
Kambe M, Miyamoto Y, Hayashi M
Biochimica et biophysica acta1395(2)209-19(1998 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The synergy of circulating factor suPAR and APOL1 G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD.
Title: A tripartite complex of suPAR, APOL1 risk variants and ?

Tat PTD-Endostatin-RGD showed high penetration ability through ocular barriers, bound specifically to integrin alpha5beta3 and effectively inhibited the abnormal angiogenesis. Tat PTD-Endostatin-RGD represents a potent novel drug applied via eye drops for fundus oculi neovascularization diseases.
Title: Tat PTD-Endostatin-RGD: A novel protein with anti-angiogenesis effect in retina via eye drops.

Suggest that alphavbeta3 integrin plays an important role in coordinating hepatocyte division during liver regeneration after partial hepatectomy via crosstalk with fibrin ECM.
Title: ?Fibrin-mediated integrin signaling plays a critical role in hepatic regeneration after partial hepatectomy in mice.

Angiogenic activity in the atherosclerotic plaques coincides with alphavbeta3-integrin by the adventitial vasa vasorum and intraplaque neovascularization.
Title: Quantification of Endothelial ?v?3 Expression with High-Frequency Ultrasound and Targeted Microbubbles: In?Vitro?and In?Vivo Studies.

This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.
Title: ?v Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.

The following Itgav gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itgav cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu30049	XM_006498807.4 Latest version!	Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu17708	NM_008402.3 Latest version!	Mus musculus integrin alpha V (Itgav), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$615.30 $879.00
View Old Accession Versions >>
OMu30049	XM_006498807.3	Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itgav ( XM_006498807.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498870.1 Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu30049
Clone ID Related Accession (Same CDS sequence)	XM_006498807.3 , XM_006498807.4
Accession Version	XM_006498807.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3132bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	integrin alpha-V isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006498807.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCGATGT TTCTCCTGGT GGGAGCCCCC AAAGCGAACA CGACCCAGCC TGGGATTGTA 
GAAGGAGGGC AAGTTCTCAA ATGTGAATGC TCATCCAGCC GCCGGTGCCA GCCCATTGAG 
TTTGATTCAA CAGGCAATCG AGATTATGCC AAAGATGACC CACTGGAGTT TAAGTCCCAC 
CAGTGGTTTG GAGCCTCTGT GAGGTCAAAG CAGGATAAAA TCTTGGCCTG TGCTCCATTG 
TACCACTGGA GGACTGAGAT GAAGCAGGAG AGAGAGCCAG TTGGAACCTG CTTTCTTCAG 
GACGGCACAA AGACCGTTGA GTATGCTCCA TGCAGGTCAA AAAATATTGA TGCTGATGGC 
CAGGGATTTT GTCAAGGAGG ATTCAGCATT GATTTTACTA AAGCTGACAG AGTACTTCTC 
GGTGGTCCTG GTAGCTTTTA TTGGCAAGGT CAGCTCATTT CGGACCAAGT GGCAGAAATC 
ATATCTAAAT ATGACCCAAA TGTCTACAGC ATCAAATATA ATAACCAATT AGCAACACGG 
ACTGCACAAG CAATTTTTGA TGACAGTTAT TTGGGTTACT CTGTGGCCGT GGGAGACTTC 
AATGGTGACG GCATTGAAGA TTTTGTCTCA GGAGTTCCAA GAGCAGCAAG GACTTTGGGA 
ATGGTTTATA TTTATGATGG GAAAAATATG TCCTCTTTAC ACAATTTTAC TGGTGAACAG 
ATGGCTGCGT ATTTTGGATT TTCTGTAGCT GCTACTGACA TTAATGGGGA TGATTACGCA 
GATGTGTTTA TTGGAGCCCC CCTGTTCATG GACCGAGGTT CCGATGGGAA ACTCCAGGAG 
GTTGGCCAGG TCTCAGTGTC TCTGCAGAGA GCAGTGGGAG ACTTCCAGAC TACAAAGCTG 
AACGGCTTTG AGGTTTTTGC CAGGTTTGGA AGTGCCATAG CTCCATTGGG AGACCTGGAC 
CAGGATGGCT TCAATGATAT TGCAATTGCT GCTCCCTATG GTGGTGAAGA TAAGAAGGGA 
CTTGTTTATA TCTTCAATGG AAGGTCCACA GGCTTGAATT CGGTGCCATC TCAAATCCTC 
GAGGGGCAGT GGGCTGCTCA GAGCATGCCC CCAAGCTTTG GCTATTCAAT GAAGGGAGCT 
ACAGATGTAG ACAGGAATGG ATATCCAGAC TTAGTTGTAG GAGCTTTTGG TGTGGATCGA 
GCTGTCTTAT ACAGAGCCAG ACCCGTTGTC ACTGTAAATG CTGGCCTTGA AGTGTACCCT 
AGCATTTTAA ATCAAGACAA TAAGATCTGC CCGTTGCCTG GGACAGCTCT CAAGGTTTCC 
TGTTTTAATG TCAGATTCTG CTTAAAGGCA GATGGCAAGG GAACCCTTCC TCGGAAGCTC 
CACTTCCAGG TGGAGCTTCT ACTGGATAAA CTCAAGCAGA AGGGAGCCAT CCGACGAGCA 
CTGTTTCTCC ATAACAGGTC CCCGGTCCAC TCCAAGACCA TGACTGTTTT CAGGGGGGGA 
CAGATGCAGT GTGAGGAACT GGTCGCCTAT CTTCGGGATG AATCTGAATT TAGAGACAAG 
CTCACTCCCA TCACCATTTT CATGGAGTAT CGGTTGGACC AGAGAACGGC TGCTGATGCC 
ACAGGCTTGC AGCCCATCCT GAACCAGTTC ACTCCGGCCA ACGTCAGTCG GCAGGCTCAT 
ATTCTACTTG ACTGTGGTGA AGACAATGTC TGTAAACCTA AATTGGAAGT TTCTGTAAAT 
AGTGATCAAA AGAAGATCTA TATTGGGGAC GACAACCCTC TGACACTGAC TGTGAAGGCG 
CAGAATCAAG GGGAAGGCGC CTATGAAGCT GAGCTCATCG TTTCTATCCC ACCGCAGGCT 
GACTTCATCG GGGTTGTCCG GAACAACGAA GCCTTAGCAA GACTGTCCTG TGCATTTAAG 
ACAGAAAACC AAACTCGGCA GGTGGTGTGC GACCTTGGAA ACCCGATGAA GGCTGGAACT 
CAACTGCTCG CTGGTCTTCG TTTCAGCGTG CACCAGCAGT CAGAGATGGA TACTTCTGTG 
AAGTTTGACT TGAAAATCCA GAGCTCTAAT TCTTTTGACA ATGTAAGTCC AGTTGTGTCT 
TACAAGGTTG ACCTCGCCGT TTTGGCTGCT GTGGAGATAA GAGGAGTTTC AAGTCCAGAT 
CATATCTTTC TTCCAATTCC AAATTGGGAG TACAAGGAAA ACCCTGAGAC TGAAGAAGAC 
GTTGGGCCTA TTGTTCAGCA CATATATGAG CTGAGAAACA ATGGTCCAAG TTCATTCAGC 
AAGGCAATTC TAAATCTCCA GTGGCCTTAC AAATACAACA ACAACACTCT GTTGTACATT 
CTTCATTACG ACATTGACGG GCCAATGAAC TGCACGGCAG ATACAGAGAT CAACCCTTTG 
AGAATCAAGA CACCCGAAAA GAATGACACA GCGGCGGCGG GACAGGGAGA AAGGAATCAT 
CTCATCACCA AGCGGGATCT CACCCTCAGA GAGGGAGATG TTCACACTTT GGGCTGTGGA 
ATCGCCAAGT GCTTGCAGAT CACCTGCCAG GTTGGTCGAC TGGATAGAGG CAAGAGCGCA 
ATCCTGTACG TGAAATCCCT GCTGTGGACC GAGACGTTCA TGAACAAGGA GAACCAGAAC 
CATTCCTATT CGCTGAAGTC ATCTGCTTCC TTTAATATCA TAGAATTCCC TTACAAGAAC 
CTGCCGATCG AGGATCTCTT CAACTCTACA CTAGTCACCA CTAACATCAC CTGGGGCATT 
CAGCCGGCGC CCATGCCTGT GCCTGTGTGG GTGATCATCT TGGCAGTTCT CGCAGGGCTG 
CTGCTACTGG CTGTGTTGGT ATTTGTAATG TACAGGATGG GCTTTTTCAA ACGTGTCCGA 
CCACCTCAAG AAGAGCAAGA AAGAGAACAG CTTCAGCCTC ATGAGAATGG CGAAGGAAAC 
TCTGAAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498870.1
CDS	2433..5564
Translation	MAAPGRLLLRPRPGGLLLLLPGLLLPLADAFNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAVGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILEGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLHFQVELLLDKLKQKGAIRRALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAADATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVNSDQKKIYIGDDNPLTLTVKAQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKENPETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLYILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAAGQGERNHLITKRDLTLREGDVHTLGCGIAKCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	XM_006498807.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498807.4

ORF Insert Sequence:

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCGATGT TTCTCCTGGT GGGAGCCCCC AAAGCGAACA CGACCCAGCC TGGGATTGTA 
GAAGGAGGGC AAGTTCTCAA ATGTGAATGC TCATCCAGCC GCCGGTGCCA GCCCATTGAG 
TTTGATTCAA CAGGCAATCG AGATTATGCC AAAGATGACC CACTGGAGTT TAAGTCCCAC 
CAGTGGTTTG GAGCCTCTGT GAGGTCAAAG CAGGATAAAA TCTTGGCCTG TGCTCCATTG 
TACCACTGGA GGACTGAGAT GAAGCAGGAG AGAGAGCCAG TTGGAACCTG CTTTCTTCAG 
GACGGCACAA AGACCGTTGA GTATGCTCCA TGCAGGTCAA AAAATATTGA TGCTGATGGC 
CAGGGATTTT GTCAAGGAGG ATTCAGCATT GATTTTACTA AAGCTGACAG AGTACTTCTC 
GGTGGTCCTG GTAGCTTTTA TTGGCAAGGT CAGCTCATTT CGGACCAAGT GGCAGAAATC 
ATATCTAAAT ATGACCCAAA TGTCTACAGC ATCAAATATA ATAACCAATT AGCAACACGG 
ACTGCACAAG CAATTTTTGA TGACAGTTAT TTGGGTTACT CTGTGGCCGT GGGAGACTTC 
AATGGTGACG GCATTGAAGA TTTTGTCTCA GGAGTTCCAA GAGCAGCAAG GACTTTGGGA 
ATGGTTTATA TTTATGATGG GAAAAATATG TCCTCTTTAC ACAATTTTAC TGGTGAACAG 
ATGGCTGCGT ATTTTGGATT TTCTGTAGCT GCTACTGACA TTAATGGGGA TGATTACGCA 
GATGTGTTTA TTGGAGCCCC CCTGTTCATG GACCGAGGTT CCGATGGGAA ACTCCAGGAG 
GTTGGCCAGG TCTCAGTGTC TCTGCAGAGA GCAGTGGGAG ACTTCCAGAC TACAAAGCTG 
AACGGCTTTG AGGTTTTTGC CAGGTTTGGA AGTGCCATAG CTCCATTGGG AGACCTGGAC 
CAGGATGGCT TCAATGATAT TGCAATTGCT GCTCCCTATG GTGGTGAAGA TAAGAAGGGA 
CTTGTTTATA TCTTCAATGG AAGGTCCACA GGCTTGAATT CGGTGCCATC TCAAATCCTC 
GAGGGGCAGT GGGCTGCTCA GAGCATGCCC CCAAGCTTTG GCTATTCAAT GAAGGGAGCT 
ACAGATGTAG ACAGGAATGG ATATCCAGAC TTAGTTGTAG GAGCTTTTGG TGTGGATCGA 
GCTGTCTTAT ACAGAGCCAG ACCCGTTGTC ACTGTAAATG CTGGCCTTGA AGTGTACCCT 
AGCATTTTAA ATCAAGACAA TAAGATCTGC CCGTTGCCTG GGACAGCTCT CAAGGTTTCC 
TGTTTTAATG TCAGATTCTG CTTAAAGGCA GATGGCAAGG GAACCCTTCC TCGGAAGCTC 
CACTTCCAGG TGGAGCTTCT ACTGGATAAA CTCAAGCAGA AGGGAGCCAT CCGACGAGCA 
CTGTTTCTCC ATAACAGGTC CCCGGTCCAC TCCAAGACCA TGACTGTTTT CAGGGGGGGA 
CAGATGCAGT GTGAGGAACT GGTCGCCTAT CTTCGGGATG AATCTGAATT TAGAGACAAG 
CTCACTCCCA TCACCATTTT CATGGAGTAT CGGTTGGACC AGAGAACGGC TGCTGATGCC 
ACAGGCTTGC AGCCCATCCT GAACCAGTTC ACTCCGGCCA ACGTCAGTCG GCAGGCTCAT 
ATTCTACTTG ACTGTGGTGA AGACAATGTC TGTAAACCTA AATTGGAAGT TTCTGTAAAT 
AGTGATCAAA AGAAGATCTA TATTGGGGAC GACAACCCTC TGACACTGAC TGTGAAGGCG 
CAGAATCAAG GGGAAGGCGC CTATGAAGCT GAGCTCATCG TTTCTATCCC ACCGCAGGCT 
GACTTCATCG GGGTTGTCCG GAACAACGAA GCCTTAGCAA GACTGTCCTG TGCATTTAAG 
ACAGAAAACC AAACTCGGCA GGTGGTGTGC GACCTTGGAA ACCCGATGAA GGCTGGAACT 
CAACTGCTCG CTGGTCTTCG TTTCAGCGTG CACCAGCAGT CAGAGATGGA TACTTCTGTG 
AAGTTTGACT TGAAAATCCA GAGCTCTAAT TCTTTTGACA ATGTAAGTCC AGTTGTGTCT 
TACAAGGTTG ACCTCGCCGT TTTGGCTGCT GTGGAGATAA GAGGAGTTTC AAGTCCAGAT 
CATATCTTTC TTCCAATTCC AAATTGGGAG TACAAGGAAA ACCCTGAGAC TGAAGAAGAC 
GTTGGGCCTA TTGTTCAGCA CATATATGAG CTGAGAAACA ATGGTCCAAG TTCATTCAGC 
AAGGCAATTC TAAATCTCCA GTGGCCTTAC AAATACAACA ACAACACTCT GTTGTACATT 
CTTCATTACG ACATTGACGG GCCAATGAAC TGCACGGCAG ATACAGAGAT CAACCCTTTG 
AGAATCAAGA CACCCGAAAA GAATGACACA GCGGCGGCGG GACAGGGAGA AAGGAATCAT 
CTCATCACCA AGCGGGATCT CACCCTCAGA GAGGGAGATG TTCACACTTT GGGCTGTGGA 
ATCGCCAAGT GCTTGCAGAT CACCTGCCAG GTTGGTCGAC TGGATAGAGG CAAGAGCGCA 
ATCCTGTACG TGAAATCCCT GCTGTGGACC GAGACGTTCA TGAACAAGGA GAACCAGAAC 
CATTCCTATT CGCTGAAGTC ATCTGCTTCC TTTAATATCA TAGAATTCCC TTACAAGAAC 
CTGCCGATCG AGGATCTCTT CAACTCTACA CTAGTCACCA CTAACATCAC CTGGGGCATT 
CAGCCGGCGC CCATGCCTGT GCCTGTGTGG GTGATCATCT TGGCAGTTCT CGCAGGGCTG 
CTGCTACTGG CTGTGTTGGT ATTTGTAATG TACAGGATGG GCTTTTTCAA ACGTGTCCGA 
CCACCTCAAG AAGAGCAAGA AAGAGAACAG CTTCAGCCTC ATGAGAATGG CGAAGGAAAC 
TCTGAAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgav ( NM_008402.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032428.2 Mus musculus integrin alpha V (Itgav), mRNA.

Price & Availability↑

CloneID	OMu17708
Clone ID Related Accession (Same CDS sequence)	NM_008402.3
Accession Version	NM_008402.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3135bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	integrin alpha-V precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL772301.7 and AK149984.1. On May 3, 2013 this sequence version replaced NM_008402.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The coding region has been updated to represent a CDS sequence that is better supported by available transcript data and the reference genome sequence. The protein length is unchanged. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U14135.1, BC133682.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCCAGGA TGTTTCTCCT GGTGGGAGCC CCCAAAGCGA ACACGACCCA GCCTGGGATT 
GTAGAAGGAG GGCAAGTTCT CAAATGTGAA TGCTCATCCA GCCGCCGGTG CCAGCCCATT 
GAGTTTGATT CAACAGGCAA TCGAGATTAT GCCAAAGATG ACCCACTGGA GTTTAAGTCC 
CACCAGTGGT TTGGAGCCTC TGTGAGGTCA AAGCAGGATA AAATCTTGGC CTGTGCTCCA 
TTGTACCACT GGAGGACTGA GATGAAGCAG GAGAGAGAGC CAGTTGGAAC CTGCTTTCTT 
CAGGACGGCA CAAAGACCGT TGAGTATGCT CCATGCAGGT CAAAAAATAT TGATGCTGAT 
GGCCAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTCGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTCA TTTCGGACCA AGTGGCAGAA 
ATCATATCTA AATATGACCC AAATGTCTAC AGCATCAAAT ATAATAACCA ATTAGCAACA 
CGGACTGCAC AAGCAATTTT TGATGACAGT TATTTGGGTT ACTCTGTGGC CGTGGGAGAC 
TTCAATGGTG ACGGCATTGA AGATTTTGTC TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAAAAT ATGTCCTCTT TACACAATTT TACTGGTGAA 
CAGATGGCTG CGTATTTTGG ATTTTCTGTA GCTGCTACTG ACATTAATGG GGATGATTAC 
GCAGATGTGT TTATTGGAGC CCCCCTGTTC ATGGACCGAG GTTCCGATGG GAAACTCCAG 
GAGGTTGGCC AGGTCTCAGT GTCTCTGCAG AGAGCAGTGG GAGACTTCCA GACTACAAAG 
CTGAACGGCT TTGAGGTTTT TGCCAGGTTT GGAAGTGCCA TAGCTCCATT GGGAGACCTG 
GACCAGGATG GCTTCAATGA TATTGCAATT GCTGCTCCCT ATGGTGGTGA AGATAAGAAG 
GGACTTGTTT ATATCTTCAA TGGAAGGTCC ACAGGCTTGA ATTCGGTGCC ATCTCAAATC 
CTCGAGGGGC AGTGGGCTGC TCAGAGCATG CCCCCAAGCT TTGGCTATTC AATGAAGGGA 
GCTACAGATG TAGACAGGAA TGGATATCCA GACTTAGTTG TAGGAGCTTT TGGTGTGGAT 
CGAGCTGTCT TATACAGAGC CAGACCCGTT GTCACTGTAA ATGCTGGCCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAGATC TGCCCGTTGC CTGGGACAGC TCTCAAGGTT 
TCCTGTTTTA ATGTCAGATT CTGCTTAAAG GCAGATGGCA AGGGAACCCT TCCTCGGAAG 
CTCCACTTCC AGGTGGAGCT TCTACTGGAT AAACTCAAGC AGAAGGGAGC CATCCGACGA 
GCACTGTTTC TCCATAACAG GTCCCCGGTC CACTCCAAGA CCATGACTGT TTTCAGGGGG 
GGACAGATGC AGTGTGAGGA ACTGGTCGCC TATCTTCGGG ATGAATCTGA ATTTAGAGAC 
AAGCTCACTC CCATCACCAT TTTCATGGAG TATCGGTTGG ACCAGAGAAC GGCTGCTGAT 
GCCACAGGCT TGCAGCCCAT CCTGAACCAG TTCACTCCGG CCAACGTCAG TCGGCAGGCT 
CATATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CTAAATTGGA AGTTTCTGTA 
AATAGTGATC AAAAGAAGAT CTATATTGGG GACGACAACC CTCTGACACT GACTGTGAAG 
GCGCAGAATC AAGGGGAAGG CGCCTATGAA GCTGAGCTCA TCGTTTCTAT CCCACCGCAG 
GCTGACTTCA TCGGGGTTGT CCGGAACAAC GAAGCCTTAG CAAGACTGTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG GCAGGTGGTG TGCGACCTTG GAAACCCGAT GAAGGCTGGA 
ACTCAACTGC TCGCTGGTCT TCGTTTCAGC GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAGTTTG ACTTGAAAAT CCAGAGCTCT AATTCTTTTG ACAATGTAAG TCCAGTTGTG 
TCTTACAAGG TTGACCTCGC CGTTTTGGCT GCTGTGGAGA TAAGAGGAGT TTCAAGTCCA 
GATCATATCT TTCTTCCAAT TCCAAATTGG GAGTACAAGG AAAACCCTGA GACTGAAGAA 
GACGTTGGGC CTATTGTTCA GCACATATAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TTCTAAATCT CCAGTGGCCT TACAAATACA ACAACAACAC TCTGTTGTAC 
ATTCTTCATT ACGACATTGA CGGGCCAATG AACTGCACGG CAGATACAGA GATCAACCCT 
TTGAGAATCA AGACACCCGA AAAGAATGAC ACAGCGGCGG CGGGACAGGG AGAAAGGAAT 
CATCTCATCA CCAAGCGGGA TCTCACCCTC AGAGAGGGAG ATGTTCACAC TTTGGGCTGT 
GGAATCGCCA AGTGCTTGCA GATCACCTGC CAGGTTGGTC GACTGGATAG AGGCAAGAGC 
GCAATCCTGT ACGTGAAATC CCTGCTGTGG ACCGAGACGT TCATGAACAA GGAGAACCAG 
AACCATTCCT ATTCGCTGAA GTCATCTGCT TCCTTTAATA TCATAGAATT CCCTTACAAG 
AACCTGCCGA TCGAGGATCT CTTCAACTCT ACACTAGTCA CCACTAACAT CACCTGGGGC 
ATTCAGCCGG CGCCCATGCC TGTGCCTGTG TGGGTGATCA TCTTGGCAGT TCTCGCAGGG 
CTGCTGCTAC TGGCTGTGTT GGTATTTGTA ATGTACAGGA TGGGCTTTTT CAAACGTGTC 
CGACCACCTC AAGAAGAGCA AGAAAGAGAA CAGCTTCAGC CTCATGAGAA TGGCGAAGGA 
AACTCTGAAA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032428.2
CDS	339..3473
Translation	MAAPGRLLLRPRPGGLLLLLPGLLLPLADAFNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAVGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILEGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLHFQVELLLDKLKQKGAIRRALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAADATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVNSDQKKIYIGDDNPLTLTVKAQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKENPETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLYILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAAGQGERNHLITKRDLTLREGDVHTLGCGIAKCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_008402.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha V (Itgav), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008402.3

ORF Insert Sequence:

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCCAGGA TGTTTCTCCT GGTGGGAGCC CCCAAAGCGA ACACGACCCA GCCTGGGATT 
GTAGAAGGAG GGCAAGTTCT CAAATGTGAA TGCTCATCCA GCCGCCGGTG CCAGCCCATT 
GAGTTTGATT CAACAGGCAA TCGAGATTAT GCCAAAGATG ACCCACTGGA GTTTAAGTCC 
CACCAGTGGT TTGGAGCCTC TGTGAGGTCA AAGCAGGATA AAATCTTGGC CTGTGCTCCA 
TTGTACCACT GGAGGACTGA GATGAAGCAG GAGAGAGAGC CAGTTGGAAC CTGCTTTCTT 
CAGGACGGCA CAAAGACCGT TGAGTATGCT CCATGCAGGT CAAAAAATAT TGATGCTGAT 
GGCCAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTCGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTCA TTTCGGACCA AGTGGCAGAA 
ATCATATCTA AATATGACCC AAATGTCTAC AGCATCAAAT ATAATAACCA ATTAGCAACA 
CGGACTGCAC AAGCAATTTT TGATGACAGT TATTTGGGTT ACTCTGTGGC CGTGGGAGAC 
TTCAATGGTG ACGGCATTGA AGATTTTGTC TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAAAAT ATGTCCTCTT TACACAATTT TACTGGTGAA 
CAGATGGCTG CGTATTTTGG ATTTTCTGTA GCTGCTACTG ACATTAATGG GGATGATTAC 
GCAGATGTGT TTATTGGAGC CCCCCTGTTC ATGGACCGAG GTTCCGATGG GAAACTCCAG 
GAGGTTGGCC AGGTCTCAGT GTCTCTGCAG AGAGCAGTGG GAGACTTCCA GACTACAAAG 
CTGAACGGCT TTGAGGTTTT TGCCAGGTTT GGAAGTGCCA TAGCTCCATT GGGAGACCTG 
GACCAGGATG GCTTCAATGA TATTGCAATT GCTGCTCCCT ATGGTGGTGA AGATAAGAAG 
GGACTTGTTT ATATCTTCAA TGGAAGGTCC ACAGGCTTGA ATTCGGTGCC ATCTCAAATC 
CTCGAGGGGC AGTGGGCTGC TCAGAGCATG CCCCCAAGCT TTGGCTATTC AATGAAGGGA 
GCTACAGATG TAGACAGGAA TGGATATCCA GACTTAGTTG TAGGAGCTTT TGGTGTGGAT 
CGAGCTGTCT TATACAGAGC CAGACCCGTT GTCACTGTAA ATGCTGGCCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAGATC TGCCCGTTGC CTGGGACAGC TCTCAAGGTT 
TCCTGTTTTA ATGTCAGATT CTGCTTAAAG GCAGATGGCA AGGGAACCCT TCCTCGGAAG 
CTCCACTTCC AGGTGGAGCT TCTACTGGAT AAACTCAAGC AGAAGGGAGC CATCCGACGA 
GCACTGTTTC TCCATAACAG GTCCCCGGTC CACTCCAAGA CCATGACTGT TTTCAGGGGG 
GGACAGATGC AGTGTGAGGA ACTGGTCGCC TATCTTCGGG ATGAATCTGA ATTTAGAGAC 
AAGCTCACTC CCATCACCAT TTTCATGGAG TATCGGTTGG ACCAGAGAAC GGCTGCTGAT 
GCCACAGGCT TGCAGCCCAT CCTGAACCAG TTCACTCCGG CCAACGTCAG TCGGCAGGCT 
CATATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CTAAATTGGA AGTTTCTGTA 
AATAGTGATC AAAAGAAGAT CTATATTGGG GACGACAACC CTCTGACACT GACTGTGAAG 
GCGCAGAATC AAGGGGAAGG CGCCTATGAA GCTGAGCTCA TCGTTTCTAT CCCACCGCAG 
GCTGACTTCA TCGGGGTTGT CCGGAACAAC GAAGCCTTAG CAAGACTGTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG GCAGGTGGTG TGCGACCTTG GAAACCCGAT GAAGGCTGGA 
ACTCAACTGC TCGCTGGTCT TCGTTTCAGC GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAGTTTG ACTTGAAAAT CCAGAGCTCT AATTCTTTTG ACAATGTAAG TCCAGTTGTG 
TCTTACAAGG TTGACCTCGC CGTTTTGGCT GCTGTGGAGA TAAGAGGAGT TTCAAGTCCA 
GATCATATCT TTCTTCCAAT TCCAAATTGG GAGTACAAGG AAAACCCTGA GACTGAAGAA 
GACGTTGGGC CTATTGTTCA GCACATATAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TTCTAAATCT CCAGTGGCCT TACAAATACA ACAACAACAC TCTGTTGTAC 
ATTCTTCATT ACGACATTGA CGGGCCAATG AACTGCACGG CAGATACAGA GATCAACCCT 
TTGAGAATCA AGACACCCGA AAAGAATGAC ACAGCGGCGG CGGGACAGGG AGAAAGGAAT 
CATCTCATCA CCAAGCGGGA TCTCACCCTC AGAGAGGGAG ATGTTCACAC TTTGGGCTGT 
GGAATCGCCA AGTGCTTGCA GATCACCTGC CAGGTTGGTC GACTGGATAG AGGCAAGAGC 
GCAATCCTGT ACGTGAAATC CCTGCTGTGG ACCGAGACGT TCATGAACAA GGAGAACCAG 
AACCATTCCT ATTCGCTGAA GTCATCTGCT TCCTTTAATA TCATAGAATT CCCTTACAAG 
AACCTGCCGA TCGAGGATCT CTTCAACTCT ACACTAGTCA CCACTAACAT CACCTGGGGC 
ATTCAGCCGG CGCCCATGCC TGTGCCTGTG TGGGTGATCA TCTTGGCAGT TCTCGCAGGG 
CTGCTGCTAC TGGCTGTGTT GGTATTTGTA ATGTACAGGA TGGGCTTTTT CAAACGTGTC 
CGACCACCTC AAGAAGAGCA AGAAAGAGAA CAGCTTCAGC CTCATGAGAA TGGCGAAGGA 
AACTCTGAAA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgav ( XM_006498807.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498870.1 Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.

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CloneID	OMu30049
Clone ID Related Accession (Same CDS sequence)	XM_006498807.3 , XM_006498807.4
Accession Version	XM_006498807.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3132bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	integrin alpha-V isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498807.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCGATGT TTCTCCTGGT GGGAGCCCCC AAAGCGAACA CGACCCAGCC TGGGATTGTA 
GAAGGAGGGC AAGTTCTCAA ATGTGAATGC TCATCCAGCC GCCGGTGCCA GCCCATTGAG 
TTTGATTCAA CAGGCAATCG AGATTATGCC AAAGATGACC CACTGGAGTT TAAGTCCCAC 
CAGTGGTTTG GAGCCTCTGT GAGGTCAAAG CAGGATAAAA TCTTGGCCTG TGCTCCATTG 
TACCACTGGA GGACTGAGAT GAAGCAGGAG AGAGAGCCAG TTGGAACCTG CTTTCTTCAG 
GACGGCACAA AGACCGTTGA GTATGCTCCA TGCAGGTCAA AAAATATTGA TGCTGATGGC 
CAGGGATTTT GTCAAGGAGG ATTCAGCATT GATTTTACTA AAGCTGACAG AGTACTTCTC 
GGTGGTCCTG GTAGCTTTTA TTGGCAAGGT CAGCTCATTT CGGACCAAGT GGCAGAAATC 
ATATCTAAAT ATGACCCAAA TGTCTACAGC ATCAAATATA ATAACCAATT AGCAACACGG 
ACTGCACAAG CAATTTTTGA TGACAGTTAT TTGGGTTACT CTGTGGCCGT GGGAGACTTC 
AATGGTGACG GCATTGAAGA TTTTGTCTCA GGAGTTCCAA GAGCAGCAAG GACTTTGGGA 
ATGGTTTATA TTTATGATGG GAAAAATATG TCCTCTTTAC ACAATTTTAC TGGTGAACAG 
ATGGCTGCGT ATTTTGGATT TTCTGTAGCT GCTACTGACA TTAATGGGGA TGATTACGCA 
GATGTGTTTA TTGGAGCCCC CCTGTTCATG GACCGAGGTT CCGATGGGAA ACTCCAGGAG 
GTTGGCCAGG TCTCAGTGTC TCTGCAGAGA GCAGTGGGAG ACTTCCAGAC TACAAAGCTG 
AACGGCTTTG AGGTTTTTGC CAGGTTTGGA AGTGCCATAG CTCCATTGGG AGACCTGGAC 
CAGGATGGCT TCAATGATAT TGCAATTGCT GCTCCCTATG GTGGTGAAGA TAAGAAGGGA 
CTTGTTTATA TCTTCAATGG AAGGTCCACA GGCTTGAATT CGGTGCCATC TCAAATCCTC 
GAGGGGCAGT GGGCTGCTCA GAGCATGCCC CCAAGCTTTG GCTATTCAAT GAAGGGAGCT 
ACAGATGTAG ACAGGAATGG ATATCCAGAC TTAGTTGTAG GAGCTTTTGG TGTGGATCGA 
GCTGTCTTAT ACAGAGCCAG ACCCGTTGTC ACTGTAAATG CTGGCCTTGA AGTGTACCCT 
AGCATTTTAA ATCAAGACAA TAAGATCTGC CCGTTGCCTG GGACAGCTCT CAAGGTTTCC 
TGTTTTAATG TCAGATTCTG CTTAAAGGCA GATGGCAAGG GAACCCTTCC TCGGAAGCTC 
CACTTCCAGG TGGAGCTTCT ACTGGATAAA CTCAAGCAGA AGGGAGCCAT CCGACGAGCA 
CTGTTTCTCC ATAACAGGTC CCCGGTCCAC TCCAAGACCA TGACTGTTTT CAGGGGGGGA 
CAGATGCAGT GTGAGGAACT GGTCGCCTAT CTTCGGGATG AATCTGAATT TAGAGACAAG 
CTCACTCCCA TCACCATTTT CATGGAGTAT CGGTTGGACC AGAGAACGGC TGCTGATGCC 
ACAGGCTTGC AGCCCATCCT GAACCAGTTC ACTCCGGCCA ACGTCAGTCG GCAGGCTCAT 
ATTCTACTTG ACTGTGGTGA AGACAATGTC TGTAAACCTA AATTGGAAGT TTCTGTAAAT 
AGTGATCAAA AGAAGATCTA TATTGGGGAC GACAACCCTC TGACACTGAC TGTGAAGGCG 
CAGAATCAAG GGGAAGGCGC CTATGAAGCT GAGCTCATCG TTTCTATCCC ACCGCAGGCT 
GACTTCATCG GGGTTGTCCG GAACAACGAA GCCTTAGCAA GACTGTCCTG TGCATTTAAG 
ACAGAAAACC AAACTCGGCA GGTGGTGTGC GACCTTGGAA ACCCGATGAA GGCTGGAACT 
CAACTGCTCG CTGGTCTTCG TTTCAGCGTG CACCAGCAGT CAGAGATGGA TACTTCTGTG 
AAGTTTGACT TGAAAATCCA GAGCTCTAAT TCTTTTGACA ATGTAAGTCC AGTTGTGTCT 
TACAAGGTTG ACCTCGCCGT TTTGGCTGCT GTGGAGATAA GAGGAGTTTC AAGTCCAGAT 
CATATCTTTC TTCCAATTCC AAATTGGGAG TACAAGGAAA ACCCTGAGAC TGAAGAAGAC 
GTTGGGCCTA TTGTTCAGCA CATATATGAG CTGAGAAACA ATGGTCCAAG TTCATTCAGC 
AAGGCAATTC TAAATCTCCA GTGGCCTTAC AAATACAACA ACAACACTCT GTTGTACATT 
CTTCATTACG ACATTGACGG GCCAATGAAC TGCACGGCAG ATACAGAGAT CAACCCTTTG 
AGAATCAAGA CACCCGAAAA GAATGACACA GCGGCGGCGG GACAGGGAGA AAGGAATCAT 
CTCATCACCA AGCGGGATCT CACCCTCAGA GAGGGAGATG TTCACACTTT GGGCTGTGGA 
ATCGCCAAGT GCTTGCAGAT CACCTGCCAG GTTGGTCGAC TGGATAGAGG CAAGAGCGCA 
ATCCTGTACG TGAAATCCCT GCTGTGGACC GAGACGTTCA TGAACAAGGA GAACCAGAAC 
CATTCCTATT CGCTGAAGTC ATCTGCTTCC TTTAATATCA TAGAATTCCC TTACAAGAAC 
CTGCCGATCG AGGATCTCTT CAACTCTACA CTAGTCACCA CTAACATCAC CTGGGGCATT 
CAGCCGGCGC CCATGCCTGT GCCTGTGTGG GTGATCATCT TGGCAGTTCT CGCAGGGCTG 
CTGCTACTGG CTGTGTTGGT ATTTGTAATG TACAGGATGG GCTTTTTCAA ACGTGTCCGA 
CCACCTCAAG AAGAGCAAGA AAGAGAACAG CTTCAGCCTC ATGAGAATGG CGAAGGAAAC 
TCTGAAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498870.1
CDS	628..3759
Translation	MAAPGRLLLRPRPGGLLLLLPGLLLPLADAFNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAVGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILEGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLHFQVELLLDKLKQKGAIRRALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAADATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVNSDQKKIYIGDDNPLTLTVKAQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKENPETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLYILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAAGQGERNHLITKRDLTLREGDVHTLGCGIAKCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	XM_006498807.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha V (Itgav), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498807.3

ORF Insert Sequence:

ATGGCTGCTC CCGGGCGCCT GCTGCTACGC CCTCGCCCCG GCGGCCTCCT GCTGCTGCTG 
CCGGGTCTCC TGCTGCCCCT CGCCGACGCC TTCAACCTGG ACGTCGAAAG TCCCGCCGAG 
TATGCGGGTC CCGAGGGAAG TTACTTCGGA TTCGCCGTGG ACTTCTTCGA GCCCAGCACG 
TCCTCGATGT TTCTCCTGGT GGGAGCCCCC AAAGCGAACA CGACCCAGCC TGGGATTGTA 
GAAGGAGGGC AAGTTCTCAA ATGTGAATGC TCATCCAGCC GCCGGTGCCA GCCCATTGAG 
TTTGATTCAA CAGGCAATCG AGATTATGCC AAAGATGACC CACTGGAGTT TAAGTCCCAC 
CAGTGGTTTG GAGCCTCTGT GAGGTCAAAG CAGGATAAAA TCTTGGCCTG TGCTCCATTG 
TACCACTGGA GGACTGAGAT GAAGCAGGAG AGAGAGCCAG TTGGAACCTG CTTTCTTCAG 
GACGGCACAA AGACCGTTGA GTATGCTCCA TGCAGGTCAA AAAATATTGA TGCTGATGGC 
CAGGGATTTT GTCAAGGAGG ATTCAGCATT GATTTTACTA AAGCTGACAG AGTACTTCTC 
GGTGGTCCTG GTAGCTTTTA TTGGCAAGGT CAGCTCATTT CGGACCAAGT GGCAGAAATC 
ATATCTAAAT ATGACCCAAA TGTCTACAGC ATCAAATATA ATAACCAATT AGCAACACGG 
ACTGCACAAG CAATTTTTGA TGACAGTTAT TTGGGTTACT CTGTGGCCGT GGGAGACTTC 
AATGGTGACG GCATTGAAGA TTTTGTCTCA GGAGTTCCAA GAGCAGCAAG GACTTTGGGA 
ATGGTTTATA TTTATGATGG GAAAAATATG TCCTCTTTAC ACAATTTTAC TGGTGAACAG 
ATGGCTGCGT ATTTTGGATT TTCTGTAGCT GCTACTGACA TTAATGGGGA TGATTACGCA 
GATGTGTTTA TTGGAGCCCC CCTGTTCATG GACCGAGGTT CCGATGGGAA ACTCCAGGAG 
GTTGGCCAGG TCTCAGTGTC TCTGCAGAGA GCAGTGGGAG ACTTCCAGAC TACAAAGCTG 
AACGGCTTTG AGGTTTTTGC CAGGTTTGGA AGTGCCATAG CTCCATTGGG AGACCTGGAC 
CAGGATGGCT TCAATGATAT TGCAATTGCT GCTCCCTATG GTGGTGAAGA TAAGAAGGGA 
CTTGTTTATA TCTTCAATGG AAGGTCCACA GGCTTGAATT CGGTGCCATC TCAAATCCTC 
GAGGGGCAGT GGGCTGCTCA GAGCATGCCC CCAAGCTTTG GCTATTCAAT GAAGGGAGCT 
ACAGATGTAG ACAGGAATGG ATATCCAGAC TTAGTTGTAG GAGCTTTTGG TGTGGATCGA 
GCTGTCTTAT ACAGAGCCAG ACCCGTTGTC ACTGTAAATG CTGGCCTTGA AGTGTACCCT 
AGCATTTTAA ATCAAGACAA TAAGATCTGC CCGTTGCCTG GGACAGCTCT CAAGGTTTCC 
TGTTTTAATG TCAGATTCTG CTTAAAGGCA GATGGCAAGG GAACCCTTCC TCGGAAGCTC 
CACTTCCAGG TGGAGCTTCT ACTGGATAAA CTCAAGCAGA AGGGAGCCAT CCGACGAGCA 
CTGTTTCTCC ATAACAGGTC CCCGGTCCAC TCCAAGACCA TGACTGTTTT CAGGGGGGGA 
CAGATGCAGT GTGAGGAACT GGTCGCCTAT CTTCGGGATG AATCTGAATT TAGAGACAAG 
CTCACTCCCA TCACCATTTT CATGGAGTAT CGGTTGGACC AGAGAACGGC TGCTGATGCC 
ACAGGCTTGC AGCCCATCCT GAACCAGTTC ACTCCGGCCA ACGTCAGTCG GCAGGCTCAT 
ATTCTACTTG ACTGTGGTGA AGACAATGTC TGTAAACCTA AATTGGAAGT TTCTGTAAAT 
AGTGATCAAA AGAAGATCTA TATTGGGGAC GACAACCCTC TGACACTGAC TGTGAAGGCG 
CAGAATCAAG GGGAAGGCGC CTATGAAGCT GAGCTCATCG TTTCTATCCC ACCGCAGGCT 
GACTTCATCG GGGTTGTCCG GAACAACGAA GCCTTAGCAA GACTGTCCTG TGCATTTAAG 
ACAGAAAACC AAACTCGGCA GGTGGTGTGC GACCTTGGAA ACCCGATGAA GGCTGGAACT 
CAACTGCTCG CTGGTCTTCG TTTCAGCGTG CACCAGCAGT CAGAGATGGA TACTTCTGTG 
AAGTTTGACT TGAAAATCCA GAGCTCTAAT TCTTTTGACA ATGTAAGTCC AGTTGTGTCT 
TACAAGGTTG ACCTCGCCGT TTTGGCTGCT GTGGAGATAA GAGGAGTTTC AAGTCCAGAT 
CATATCTTTC TTCCAATTCC AAATTGGGAG TACAAGGAAA ACCCTGAGAC TGAAGAAGAC 
GTTGGGCCTA TTGTTCAGCA CATATATGAG CTGAGAAACA ATGGTCCAAG TTCATTCAGC 
AAGGCAATTC TAAATCTCCA GTGGCCTTAC AAATACAACA ACAACACTCT GTTGTACATT 
CTTCATTACG ACATTGACGG GCCAATGAAC TGCACGGCAG ATACAGAGAT CAACCCTTTG 
AGAATCAAGA CACCCGAAAA GAATGACACA GCGGCGGCGG GACAGGGAGA AAGGAATCAT 
CTCATCACCA AGCGGGATCT CACCCTCAGA GAGGGAGATG TTCACACTTT GGGCTGTGGA 
ATCGCCAAGT GCTTGCAGAT CACCTGCCAG GTTGGTCGAC TGGATAGAGG CAAGAGCGCA 
ATCCTGTACG TGAAATCCCT GCTGTGGACC GAGACGTTCA TGAACAAGGA GAACCAGAAC 
CATTCCTATT CGCTGAAGTC ATCTGCTTCC TTTAATATCA TAGAATTCCC TTACAAGAAC 
CTGCCGATCG AGGATCTCTT CAACTCTACA CTAGTCACCA CTAACATCAC CTGGGGCATT 
CAGCCGGCGC CCATGCCTGT GCCTGTGTGG GTGATCATCT TGGCAGTTCT CGCAGGGCTG 
CTGCTACTGG CTGTGTTGGT ATTTGTAATG TACAGGATGG GCTTTTTCAA ACGTGTCCGA 
CCACCTCAAG AAGAGCAAGA AAGAGAACAG CTTCAGCCTC ATGAGAATGG CGAAGGAAAC 
TCTGAAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.
Cell95(4)507-19(1998 Nov)
Bader BL,Rayburn H,Crowley D,Hynes RO

Characterization of the integrin alpha(v) gene promoter in mice.
Biochimica et biophysica acta1395(2)209-19(1998 Jan)
Kambe M,Miyamoto Y,Hayashi M

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Itgav cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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