Itga2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itga2
Entrez Gene ID	16398
Full Name	integrin alpha 2
Synonyms	CD49B,DX5
General protein information	Preferred Names integrin alpha 2 Names integrin alpha-2 CD49 antigen-like family member B GPIa VLA-2 receptor, alpha 2 subunit VLA-2 subunit alpha collagen receptor platelet membrane glycoprotein Ia
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 D2.2\|13 64.61 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008396.2	NP_032422.2	integrin alpha-2 precursor
NM_008396.3	NP_032422.2	integrin alpha-2 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ITGA2	NP_001159971.1
Mus musculus (house mouse)	Itga2	NP_032422.2
Gallus gallus (chicken)	ITGA2	XP_003643030.2
Danio rerio (zebrafish)	itga2.2	XP_003199352.2
	ITGA2	XP_001095246.1
Canis lupus familiaris (dog)	ITGA2	XP_005619391.1
Rattus norvegicus (Norway rat)	Itga2	XP_345157.5
Pan troglodytes (chimpanzee)	ITGA2	XP_526928.2
Xenopus tropicalis (tropical clawed frog)	itga2	XP_002933089.2
Homo sapiens (human)	ITGA2	NP_002194.2
Danio rerio (zebrafish)	LOC100333484	XP_003199351.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene and Protein Expression Profiles in a Mouse Model of Collagen-Induced Arthritis.
Gwon SY, Rhee KJ, Sung HJ
International journal of medical sciences15(1)77-85(2018)

The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.
Ha T, Moon KH, Dai L, Hatakeyama J, Yoon K, Park HS, Kong YY, Shimamura K, Kim JW
Cell reports19(2)351-363(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

low expression of alpha2beta1 integrin increased protein kinase B (AKT) activation and alpha-smooth muscle actin (alpha-SMA) expression. This occurred due to the instability of phosphatase and tensin homolog (PTEN) in myofibroblasts on fibrillar collagen.
Title: Fibrillar Type I Collagen Enhances the Differentiation and Proliferation of Myofibroblasts by Lowering

A sulfonamide-type small-molecule inhibitor of alpha2beta1 integrin decreased average platelet adhesion in individuals with the C/T807T genotype but not in those harboring C807C.
Title: Platelet response to a small molecule inhibitor of ?2?1 integrin is associated with ITGA2 C807T dimorphism.

Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.
Title: CEACAM1 regulates integrin ?IIb?3-mediated functions in platelets.

HRG binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.
Title: Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with ?2 integrin.

LG3, through interactions with alpha2beta1 integrins on recipient-derived cells leading to activation of ERK1/2 and increased migration, favors myointimal thickening
Title: The perlecan fragment LG3 regulates homing of mesenchymal stem cells and neointima formation during vascular rejection.

The following Itga2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itga2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu16695	NM_008396.3 Latest version!	Mus musculus integrin alpha 2 (Itga2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$692.30 $989.00
View Old Accession Versions >>
OMu16695	NM_008396.2	Mus musculus integrin alpha 2 (Itga2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$692.30 $989.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itga2 ( NM_008396.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032422.2 Mus musculus integrin alpha 2 (Itga2), mRNA.

Price & Availability↑

CloneID	OMu16695
Clone ID Related Accession (Same CDS sequence)	NM_008396.2 , NM_008396.3
Accession Version	NM_008396.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-25
Organism	Mus musculus(house mouse)
Product	integrin alpha-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC065139.1. On or before May 4, 2006 this sequence version replaced XM_982915.1, NM_008396.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065139.1, AK051050.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGGACCGG GACAGGCAGG GGGCGCGCTC CTGCTGCGGC TGCTAATGCT AGTTCAAGGT 
ATTTTGAATT GTCTGGCGTA TAATGTTGGC CTCCCAGGAG CGAAAATATT TTCCGGGCCT 
TCAAGTGAAC AGTTTGGGTA TTCAGTACAG CAGCTTACGA ACCCACAAGG CAACTGGCTA 
CTGGTTGGTT CACCGTGGAG TGGCTTCCCT GAGAACCGAA TGGGAGATGT GTACAAGTGC 
CCTGTGGACC TACCCACTGC CACCTGTGAA AAGCTGAATC TGCAAAATTC AGCAAGCATC 
TCAAATGTTA CCGAGATAAA GACCAACATG AGCCTGGGAT TGACCCTCAC CAGGAATCCG 
GGGACCGGAG GCTTTCTAAC CTGTGGTCCT CTCTGGGCAC ATCAGTGTGG AAATCAGTAT 
TATGCAACTG GGATCTGTTC TGATGTTAGT CCAGACTTTC AGTTCTTGAC CAGCTTTTCA 
CCTGCAGTTC AGGCTTGCCC TTCCCTCGTG GATGTTGTAG TTGTATGTGA TGAATCAAAC 
AGTATTTATC CTTGGGAAGC AGTAAAGAAC TTTTTGGTAA AGTTTGTGAC AGGCCTGGAT 
ATAGGACCTA AAAAGACACA GGTGGCGTTA ATTCAATATG CCAATGAGCC GAGAATTATA 
TTTAACTTGA ACGATTTCGA AACCAAAGAG GATATGGTCC AGGCCACATC TGAGACGCGC 
CAACATGGTG GGGACCTCAC AAACACCTTC AGAGCTATCG AATTCGCAAG AGACTACGCT 
TATTCACAGA CTTCTGGCGG GCGCCCGGGT GCTACAAAAG TCATGGTAGT TGTGACCGAT 
GGCGAGTCCC ATGATGGGTC GAAGCTGAAA ACTGTGATCC AGCAATGCAA TGATGACGAG 
ATACTGAGGT TCGGCATAGC AGTTCTTGGG TATTTAAACA GAAATGCTCT TGATACTAAA 
AATTTAATCA AAGAAATAAA AGCAATTGCT AGTACTCCAA CCGAGAGATA CTTTTTCAAT 
GTGGCCGACG AAGCGGCTCT TCTGGAGAAG GCTGGAACTC TAGGGGAGCA AATATTCAGC 
ATTGAAGGCA CTGTTCAAGG AGGAGACAAC TTCCAGATGG AAATGGCACA AGTTGGATTC 
AGTGCAGATT ACGCTCCTCA AAATGATATT CTGATGTTAG GTGCAGTGGG GGCTTTTGAC 
TGGAGTGGAA CTCTTGTCCA GGAGACATCT CACAAGCCCG TGATCTTTCC TAAACAAGCC 
TTTGACCAGG TTCTGCAGGA TAGAAACCAC AGTTCGTTTT TAGGTTACTC TGTGGCTGCA 
ATTTCTACTG AAGACGGTGT CCATTTTGTT GCTGGTGCTC CTCGAGCAAA TTATACTGGC 
CAGATAGTGT TGTACAGCGT TAACAAGCAA GGCAATGTGA CCGTGATTCA GTCTCACAGA 
GGGGACCAGA TTGGCTCCTA TTTTGGCAGT GTGCTGTGCT CAGTTGATGT AGATAAAGAC 
ACCATTACAG ACGTGCTCCT GGTAGGTGCT CCTACATACA TGAACGACCT CAAGAAAGAA 
GAGGGAAAAG TCTACCTATT TACCATCACA AAGGGCATCT TGAATCAGCA CCAGTTTCTT 
GAAGGGCCAG AAGGCACTGG AAATGCTCGG TTTGGTTCAG CAATTGCAGC CCTGTCAGAC 
ATCAACATGG ATGGCTTTAA TGATGTGATT GTCGGTTCAC CTGTAGAGAA TGAGAACTCT 
GGAGCTGTGT ACATTTACAA TGGTCACCAG GGTACCATTC GCACCAAGTA CTCCCAGAAA 
ATCCTTGGGT CCAATGGAGC CTTTAGGAGA CATCTCCAGT TCTTTGGAAG GTCCCTGGAT 
GGCTATGGTG ATTTAAATGG GGATTCCATC ACTGATGTAT CCATTGGTGC TTTGGGGCAA 
GTGATTCAAC TCTGGTCACA AAGCATTGCT GACGTGGCCA TAGAAGCTTT GTTCACTCCA 
GACAAAATCA CTTTGCTCAA CAAGGATGCT AAGATAACCC TAAAGCTCTG CTTCAGAGCA 
GAGTTTAGAC CTGCTGGGCA AAACAATCAA GTAGCCATCC TGTTTAACAT GACGCTTGAT 
GCGGACGGAC ATTCATCCAG GGTAACCTCC AGGGGGGTGT TCAGAGAAAA CAGTGAGCGA 
TTCTTGCAGA AGAATATGGT GGTAAACGAA GTGCAGAAGT GTTCTGAGCA CCACATTAGC 
ATACAGAAGC CCTCTGATGT TGTCAACCCT TTGGATCTGC GTGTGGACAT CAGTTTGGAA 
AACCCAGGCA CTAGCCCTGC CCTCGAAGCC TATTCTGAAA CTGTCAAAGT CTTCAGTATC 
CCTTTCTATA AGGAGTGTGG CAGCGATGGA ATTTGCATCT CTGACCTGAT CCTGGATGTC 
CAACAGCTGC CAGCCATTCA AACTCAATCC TTTATTGTCA GTAACCAAAA CAAGAGGTTA 
ACATTTTCAG TCATCCTGAA AAACAGAGGG GAAAGTGCAT ACAACACTGT GGTCCTGGCC 
GAGTTTTCTG AGAACTTGTT TTTTGCTTCT TTCTCCATGC CGGTCGATGG AACAGAAGTA 
ACATGTGAGG TTGGTTCATC GCAGAAATCT GTTACCTGTG ATGTGGGATA CCCTGCCTTA 
AAGAGTGAAC AGCAGGTGAC TTTTACCATT AACTTCGACT TTAATCTTCA AAACCTCCAG 
AACCAGGCGG CCATCAATTT CCAAGCCTTC AGTGAGAGCC AAGAAACAAA CAAAGCAGAC 
AATTCGGTCA GTCTCACGAT TCCTCTCCTG TATGATGCCG AACTTCACTT AACCCGATCC 
ACCAACATCA ACTTCTATGA GATCTCTTCG GATGAGAACG CTCCTTCTGT CATCAAGAGT 
GTCGAAGATA TTGGTCCTAA ATTCATCTTC TCCCTCAAGG TAACAGCCGG AAGTGCCCCA 
GTGAGCATGG CATTGGTGAC TATCCACATT CCTCAGTACA CCAAGGAAAA GAACCCACTC 
CTGTATCTGA CTGGGATACA AACAGACCAG GCTGGCGACA TCAGCTGCAC AGCAGAAATA 
AATCCACTCA AGCTACCACA CACCGCCCCT TCTGTATCTT TCAAGAATGA AAACTTCCGG 
CATACGAAAG AATTGGACTG CAGAACCACT TCCTGCAGTA ACATCACCTG CTGGCTGAAA 
GACCTTCACA TGAAAGCAGA GTACTTCATC AATGTGACAA CCAGAGTTTG GAACAGGACC 
TTTGCTGCTT CGACTTTCCA GACTGTGCAG CTGACAGCAG CGGCAGAGAT CGATACACAT 
AACCCTCAGC TCTTCGTGAT TGAGGAAAAT GCTGTCACGA TTCCCCTCAT GATAATGAAA 
CCCACGGAGA AAGCAGAAGT ACCGACAGGG GTTATCATAG GCAGCATAAT TGCGGGAATC 
CTTTTGCTGT TGGCTATGAC TGCAGGTTTG TGGAAGCTCG GCTTCTTCAA AAGACAATAT 
AAGAAAATGG GCCAAAATCC AGATGAGATG GATGAGACCA CAGAACTCAA CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032422.2
CDS	109..3645
Translation	MGPGQAGGALLLRLLMLVQGILNCLAYNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWLLVGSPWSGFPENRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMAQVGFSADYAPQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQAFDQVLQDRNHSSFLGYSVAAISTEDGVHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKITLLNKDAKITLKLCFRAEFRPAGQNNQVAILFNMTLDADGHSSRVTSRGVFRENSERFLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSIPFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLAEFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQAAINFQAFSESQETNKADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKSVEDIGPKFIFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAEINPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMTAGLWKLGFFKRQYKKMGQNPDEMDETTELNS

Target ORF information:

RefSeq Version	NM_008396.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha 2 (Itga2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008396.2

ORF Insert Sequence:

ATGGGACCGG GACAGGCAGG GGGCGCGCTC CTGCTGCGGC TGCTAATGCT AGTTCAAGGT 
ATTTTGAATT GTCTGGCGTA TAATGTTGGC CTCCCAGGAG CGAAAATATT TTCCGGGCCT 
TCAAGTGAAC AGTTTGGGTA TTCAGTACAG CAGCTTACGA ACCCACAAGG CAACTGGCTA 
CTGGTTGGTT CACCGTGGAG TGGCTTCCCT GAGAACCGAA TGGGAGATGT GTACAAGTGC 
CCTGTGGACC TACCCACTGC CACCTGTGAA AAGCTGAATC TGCAAAATTC AGCAAGCATC 
TCAAATGTTA CCGAGATAAA GACCAACATG AGCCTGGGAT TGACCCTCAC CAGGAATCCG 
GGGACCGGAG GCTTTCTAAC CTGTGGTCCT CTCTGGGCAC ATCAGTGTGG AAATCAGTAT 
TATGCAACTG GGATCTGTTC TGATGTTAGT CCAGACTTTC AGTTCTTGAC CAGCTTTTCA 
CCTGCAGTTC AGGCTTGCCC TTCCCTCGTG GATGTTGTAG TTGTATGTGA TGAATCAAAC 
AGTATTTATC CTTGGGAAGC AGTAAAGAAC TTTTTGGTAA AGTTTGTGAC AGGCCTGGAT 
ATAGGACCTA AAAAGACACA GGTGGCGTTA ATTCAATATG CCAATGAGCC GAGAATTATA 
TTTAACTTGA ACGATTTCGA AACCAAAGAG GATATGGTCC AGGCCACATC TGAGACGCGC 
CAACATGGTG GGGACCTCAC AAACACCTTC AGAGCTATCG AATTCGCAAG AGACTACGCT 
TATTCACAGA CTTCTGGCGG GCGCCCGGGT GCTACAAAAG TCATGGTAGT TGTGACCGAT 
GGCGAGTCCC ATGATGGGTC GAAGCTGAAA ACTGTGATCC AGCAATGCAA TGATGACGAG 
ATACTGAGGT TCGGCATAGC AGTTCTTGGG TATTTAAACA GAAATGCTCT TGATACTAAA 
AATTTAATCA AAGAAATAAA AGCAATTGCT AGTACTCCAA CCGAGAGATA CTTTTTCAAT 
GTGGCCGACG AAGCGGCTCT TCTGGAGAAG GCTGGAACTC TAGGGGAGCA AATATTCAGC 
ATTGAAGGCA CTGTTCAAGG AGGAGACAAC TTCCAGATGG AAATGGCACA AGTTGGATTC 
AGTGCAGATT ACGCTCCTCA AAATGATATT CTGATGTTAG GTGCAGTGGG GGCTTTTGAC 
TGGAGTGGAA CTCTTGTCCA GGAGACATCT CACAAGCCCG TGATCTTTCC TAAACAAGCC 
TTTGACCAGG TTCTGCAGGA TAGAAACCAC AGTTCGTTTT TAGGTTACTC TGTGGCTGCA 
ATTTCTACTG AAGACGGTGT CCATTTTGTT GCTGGTGCTC CTCGAGCAAA TTATACTGGC 
CAGATAGTGT TGTACAGCGT TAACAAGCAA GGCAATGTGA CCGTGATTCA GTCTCACAGA 
GGGGACCAGA TTGGCTCCTA TTTTGGCAGT GTGCTGTGCT CAGTTGATGT AGATAAAGAC 
ACCATTACAG ACGTGCTCCT GGTAGGTGCT CCTACATACA TGAACGACCT CAAGAAAGAA 
GAGGGAAAAG TCTACCTATT TACCATCACA AAGGGCATCT TGAATCAGCA CCAGTTTCTT 
GAAGGGCCAG AAGGCACTGG AAATGCTCGG TTTGGTTCAG CAATTGCAGC CCTGTCAGAC 
ATCAACATGG ATGGCTTTAA TGATGTGATT GTCGGTTCAC CTGTAGAGAA TGAGAACTCT 
GGAGCTGTGT ACATTTACAA TGGTCACCAG GGTACCATTC GCACCAAGTA CTCCCAGAAA 
ATCCTTGGGT CCAATGGAGC CTTTAGGAGA CATCTCCAGT TCTTTGGAAG GTCCCTGGAT 
GGCTATGGTG ATTTAAATGG GGATTCCATC ACTGATGTAT CCATTGGTGC TTTGGGGCAA 
GTGATTCAAC TCTGGTCACA AAGCATTGCT GACGTGGCCA TAGAAGCTTT GTTCACTCCA 
GACAAAATCA CTTTGCTCAA CAAGGATGCT AAGATAACCC TAAAGCTCTG CTTCAGAGCA 
GAGTTTAGAC CTGCTGGGCA AAACAATCAA GTAGCCATCC TGTTTAACAT GACGCTTGAT 
GCGGACGGAC ATTCATCCAG GGTAACCTCC AGGGGGGTGT TCAGAGAAAA CAGTGAGCGA 
TTCTTGCAGA AGAATATGGT GGTAAACGAA GTGCAGAAGT GTTCTGAGCA CCACATTAGC 
ATACAGAAGC CCTCTGATGT TGTCAACCCT TTGGATCTGC GTGTGGACAT CAGTTTGGAA 
AACCCAGGCA CTAGCCCTGC CCTCGAAGCC TATTCTGAAA CTGTCAAAGT CTTCAGTATC 
CCTTTCTATA AGGAGTGTGG CAGCGATGGA ATTTGCATCT CTGACCTGAT CCTGGATGTC 
CAACAGCTGC CAGCCATTCA AACTCAATCC TTTATTGTCA GTAACCAAAA CAAGAGGTTA 
ACATTTTCAG TCATCCTGAA AAACAGAGGG GAAAGTGCAT ACAACACTGT GGTCCTGGCC 
GAGTTTTCTG AGAACTTGTT TTTTGCTTCT TTCTCCATGC CGGTCGATGG AACAGAAGTA 
ACATGTGAGG TTGGTTCATC GCAGAAATCT GTTACCTGTG ATGTGGGATA CCCTGCCTTA 
AAGAGTGAAC AGCAGGTGAC TTTTACCATT AACTTCGACT TTAATCTTCA AAACCTCCAG 
AACCAGGCGG CCATCAATTT CCAAGCCTTC AGTGAGAGCC AAGAAACAAA CAAAGCAGAC 
AATTCGGTCA GTCTCACGAT TCCTCTCCTG TATGATGCCG AACTTCACTT AACCCGATCC 
ACCAACATCA ACTTCTATGA GATCTCTTCG GATGAGAACG CTCCTTCTGT CATCAAGAGT 
GTCGAAGATA TTGGTCCTAA ATTCATCTTC TCCCTCAAGG TAACAGCCGG AAGTGCCCCA 
GTGAGCATGG CATTGGTGAC TATCCACATT CCTCAGTACA CCAAGGAAAA GAACCCACTC 
CTGTATCTGA CTGGGATACA AACAGACCAG GCTGGCGACA TCAGCTGCAC AGCAGAAATA 
AATCCACTCA AGCTACCACA CACCGCCCCT TCTGTATCTT TCAAGAATGA AAACTTCCGG 
CATACGAAAG AATTGGACTG CAGAACCACT TCCTGCAGTA ACATCACCTG CTGGCTGAAA 
GACCTTCACA TGAAAGCAGA GTACTTCATC AATGTGACAA CCAGAGTTTG GAACAGGACC 
TTTGCTGCTT CGACTTTCCA GACTGTGCAG CTGACAGCAG CGGCAGAGAT CGATACACAT 
AACCCTCAGC TCTTCGTGAT TGAGGAAAAT GCTGTCACGA TTCCCCTCAT GATAATGAAA 
CCCACGGAGA AAGCAGAAGT ACCGACAGGG GTTATCATAG GCAGCATAAT TGCGGGAATC 
CTTTTGCTGT TGGCTATGAC TGCAGGTTTG TGGAAGCTCG GCTTCTTCAA AAGACAATAT 
AAGAAAATGG GCCAAAATCC AGATGAGATG GATGAGACCA CAGAACTCAA CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itga2 ( NM_008396.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032422.2 Mus musculus integrin alpha 2 (Itga2), mRNA.

Price & Availability↑

CloneID	OMu16695
Clone ID Related Accession (Same CDS sequence)	NM_008396.2 , NM_008396.3
Accession Version	NM_008396.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	integrin alpha-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK036572.1, BC065139.1, CT025598.9, AK028540.1 and CJ248007.1. On Apr 13, 2018 this sequence version replaced NM_008396.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK156604.1, AK051050.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGACCGG GACAGGCAGG GGGCGCGCTC CTGCTGCGGC TGCTAATGCT AGTTCAAGGT 
ATTTTGAATT GTCTGGCGTA TAATGTTGGC CTCCCAGGAG CGAAAATATT TTCCGGGCCT 
TCAAGTGAAC AGTTTGGGTA TTCAGTACAG CAGCTTACGA ACCCACAAGG CAACTGGCTA 
CTGGTTGGTT CACCGTGGAG TGGCTTCCCT GAGAACCGAA TGGGAGATGT GTACAAGTGC 
CCTGTGGACC TACCCACTGC CACCTGTGAA AAGCTGAATC TGCAAAATTC AGCAAGCATC 
TCAAATGTTA CCGAGATAAA GACCAACATG AGCCTGGGAT TGACCCTCAC CAGGAATCCG 
GGGACCGGAG GCTTTCTAAC CTGTGGTCCT CTCTGGGCAC ATCAGTGTGG AAATCAGTAT 
TATGCAACTG GGATCTGTTC TGATGTTAGT CCAGACTTTC AGTTCTTGAC CAGCTTTTCA 
CCTGCAGTTC AGGCTTGCCC TTCCCTCGTG GATGTTGTAG TTGTATGTGA TGAATCAAAC 
AGTATTTATC CTTGGGAAGC AGTAAAGAAC TTTTTGGTAA AGTTTGTGAC AGGCCTGGAT 
ATAGGACCTA AAAAGACACA GGTGGCGTTA ATTCAATATG CCAATGAGCC GAGAATTATA 
TTTAACTTGA ACGATTTCGA AACCAAAGAG GATATGGTCC AGGCCACATC TGAGACGCGC 
CAACATGGTG GGGACCTCAC AAACACCTTC AGAGCTATCG AATTCGCAAG AGACTACGCT 
TATTCACAGA CTTCTGGCGG GCGCCCGGGT GCTACAAAAG TCATGGTAGT TGTGACCGAT 
GGCGAGTCCC ATGATGGGTC GAAGCTGAAA ACTGTGATCC AGCAATGCAA TGATGACGAG 
ATACTGAGGT TCGGCATAGC AGTTCTTGGG TATTTAAACA GAAATGCTCT TGATACTAAA 
AATTTAATCA AAGAAATAAA AGCAATTGCT AGTACTCCAA CCGAGAGATA CTTTTTCAAT 
GTGGCCGACG AAGCGGCTCT TCTGGAGAAG GCTGGAACTC TAGGGGAGCA AATATTCAGC 
ATTGAAGGCA CTGTTCAAGG AGGAGACAAC TTCCAGATGG AAATGGCACA AGTTGGATTC 
AGTGCAGATT ACGCTCCTCA AAATGATATT CTGATGTTAG GTGCAGTGGG GGCTTTTGAC 
TGGAGTGGAA CTCTTGTCCA GGAGACATCT CACAAGCCCG TGATCTTTCC TAAACAAGCC 
TTTGACCAGG TTCTGCAGGA TAGAAACCAC AGTTCGTTTT TAGGTTACTC TGTGGCTGCA 
ATTTCTACTG AAGACGGTGT CCATTTTGTT GCTGGTGCTC CTCGAGCAAA TTATACTGGC 
CAGATAGTGT TGTACAGCGT TAACAAGCAA GGCAATGTGA CCGTGATTCA GTCTCACAGA 
GGGGACCAGA TTGGCTCCTA TTTTGGCAGT GTGCTGTGCT CAGTTGATGT AGATAAAGAC 
ACCATTACAG ACGTGCTCCT GGTAGGTGCT CCTACATACA TGAACGACCT CAAGAAAGAA 
GAGGGAAAAG TCTACCTATT TACCATCACA AAGGGCATCT TGAATCAGCA CCAGTTTCTT 
GAAGGGCCAG AAGGCACTGG AAATGCTCGG TTTGGTTCAG CAATTGCAGC CCTGTCAGAC 
ATCAACATGG ATGGCTTTAA TGATGTGATT GTCGGTTCAC CTGTAGAGAA TGAGAACTCT 
GGAGCTGTGT ACATTTACAA TGGTCACCAG GGTACCATTC GCACCAAGTA CTCCCAGAAA 
ATCCTTGGGT CCAATGGAGC CTTTAGGAGA CATCTCCAGT TCTTTGGAAG GTCCCTGGAT 
GGCTATGGTG ATTTAAATGG GGATTCCATC ACTGATGTAT CCATTGGTGC TTTGGGGCAA 
GTGATTCAAC TCTGGTCACA AAGCATTGCT GACGTGGCCA TAGAAGCTTT GTTCACTCCA 
GACAAAATCA CTTTGCTCAA CAAGGATGCT AAGATAACCC TAAAGCTCTG CTTCAGAGCA 
GAGTTTAGAC CTGCTGGGCA AAACAATCAA GTAGCCATCC TGTTTAACAT GACGCTTGAT 
GCGGACGGAC ATTCATCCAG GGTAACCTCC AGGGGGGTGT TCAGAGAAAA CAGTGAGCGA 
TTCTTGCAGA AGAATATGGT GGTAAACGAA GTGCAGAAGT GTTCTGAGCA CCACATTAGC 
ATACAGAAGC CCTCTGATGT TGTCAACCCT TTGGATCTGC GTGTGGACAT CAGTTTGGAA 
AACCCAGGCA CTAGCCCTGC CCTCGAAGCC TATTCTGAAA CTGTCAAAGT CTTCAGTATC 
CCTTTCTATA AGGAGTGTGG CAGCGATGGA ATTTGCATCT CTGACCTGAT CCTGGATGTC 
CAACAGCTGC CAGCCATTCA AACTCAATCC TTTATTGTCA GTAACCAAAA CAAGAGGTTA 
ACATTTTCAG TCATCCTGAA AAACAGAGGG GAAAGTGCAT ACAACACTGT GGTCCTGGCC 
GAGTTTTCTG AGAACTTGTT TTTTGCTTCT TTCTCCATGC CGGTCGATGG AACAGAAGTA 
ACATGTGAGG TTGGTTCATC GCAGAAATCT GTTACCTGTG ATGTGGGATA CCCTGCCTTA 
AAGAGTGAAC AGCAGGTGAC TTTTACCATT AACTTCGACT TTAATCTTCA AAACCTCCAG 
AACCAGGCGG CCATCAATTT CCAAGCCTTC AGTGAGAGCC AAGAAACAAA CAAAGCAGAC 
AATTCGGTCA GTCTCACGAT TCCTCTCCTG TATGATGCCG AACTTCACTT AACCCGATCC 
ACCAACATCA ACTTCTATGA GATCTCTTCG GATGAGAACG CTCCTTCTGT CATCAAGAGT 
GTCGAAGATA TTGGTCCTAA ATTCATCTTC TCCCTCAAGG TAACAGCCGG AAGTGCCCCA 
GTGAGCATGG CATTGGTGAC TATCCACATT CCTCAGTACA CCAAGGAAAA GAACCCACTC 
CTGTATCTGA CTGGGATACA AACAGACCAG GCTGGCGACA TCAGCTGCAC AGCAGAAATA 
AATCCACTCA AGCTACCACA CACCGCCCCT TCTGTATCTT TCAAGAATGA AAACTTCCGG 
CATACGAAAG AATTGGACTG CAGAACCACT TCCTGCAGTA ACATCACCTG CTGGCTGAAA 
GACCTTCACA TGAAAGCAGA GTACTTCATC AATGTGACAA CCAGAGTTTG GAACAGGACC 
TTTGCTGCTT CGACTTTCCA GACTGTGCAG CTGACAGCAG CGGCAGAGAT CGATACACAT 
AACCCTCAGC TCTTCGTGAT TGAGGAAAAT GCTGTCACGA TTCCCCTCAT GATAATGAAA 
CCCACGGAGA AAGCAGAAGT ACCGACAGGG GTTATCATAG GCAGCATAAT TGCGGGAATC 
CTTTTGCTGT TGGCTATGAC TGCAGGTTTG TGGAAGCTCG GCTTCTTCAA AAGACAATAT 
AAGAAAATGG GCCAAAATCC AGATGAGATG GATGAGACCA CAGAACTCAA CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032422.2
CDS	168..3704
Translation	MGPGQAGGALLLRLLMLVQGILNCLAYNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWLLVGSPWSGFPENRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMAQVGFSADYAPQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQAFDQVLQDRNHSSFLGYSVAAISTEDGVHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKITLLNKDAKITLKLCFRAEFRPAGQNNQVAILFNMTLDADGHSSRVTSRGVFRENSERFLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSIPFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLAEFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQAAINFQAFSESQETNKADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKSVEDIGPKFIFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAEINPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMTAGLWKLGFFKRQYKKMGQNPDEMDETTELNS

Target ORF information:

RefSeq Version	NM_008396.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha 2 (Itga2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008396.3

ORF Insert Sequence:

ATGGGACCGG GACAGGCAGG GGGCGCGCTC CTGCTGCGGC TGCTAATGCT AGTTCAAGGT 
ATTTTGAATT GTCTGGCGTA TAATGTTGGC CTCCCAGGAG CGAAAATATT TTCCGGGCCT 
TCAAGTGAAC AGTTTGGGTA TTCAGTACAG CAGCTTACGA ACCCACAAGG CAACTGGCTA 
CTGGTTGGTT CACCGTGGAG TGGCTTCCCT GAGAACCGAA TGGGAGATGT GTACAAGTGC 
CCTGTGGACC TACCCACTGC CACCTGTGAA AAGCTGAATC TGCAAAATTC AGCAAGCATC 
TCAAATGTTA CCGAGATAAA GACCAACATG AGCCTGGGAT TGACCCTCAC CAGGAATCCG 
GGGACCGGAG GCTTTCTAAC CTGTGGTCCT CTCTGGGCAC ATCAGTGTGG AAATCAGTAT 
TATGCAACTG GGATCTGTTC TGATGTTAGT CCAGACTTTC AGTTCTTGAC CAGCTTTTCA 
CCTGCAGTTC AGGCTTGCCC TTCCCTCGTG GATGTTGTAG TTGTATGTGA TGAATCAAAC 
AGTATTTATC CTTGGGAAGC AGTAAAGAAC TTTTTGGTAA AGTTTGTGAC AGGCCTGGAT 
ATAGGACCTA AAAAGACACA GGTGGCGTTA ATTCAATATG CCAATGAGCC GAGAATTATA 
TTTAACTTGA ACGATTTCGA AACCAAAGAG GATATGGTCC AGGCCACATC TGAGACGCGC 
CAACATGGTG GGGACCTCAC AAACACCTTC AGAGCTATCG AATTCGCAAG AGACTACGCT 
TATTCACAGA CTTCTGGCGG GCGCCCGGGT GCTACAAAAG TCATGGTAGT TGTGACCGAT 
GGCGAGTCCC ATGATGGGTC GAAGCTGAAA ACTGTGATCC AGCAATGCAA TGATGACGAG 
ATACTGAGGT TCGGCATAGC AGTTCTTGGG TATTTAAACA GAAATGCTCT TGATACTAAA 
AATTTAATCA AAGAAATAAA AGCAATTGCT AGTACTCCAA CCGAGAGATA CTTTTTCAAT 
GTGGCCGACG AAGCGGCTCT TCTGGAGAAG GCTGGAACTC TAGGGGAGCA AATATTCAGC 
ATTGAAGGCA CTGTTCAAGG AGGAGACAAC TTCCAGATGG AAATGGCACA AGTTGGATTC 
AGTGCAGATT ACGCTCCTCA AAATGATATT CTGATGTTAG GTGCAGTGGG GGCTTTTGAC 
TGGAGTGGAA CTCTTGTCCA GGAGACATCT CACAAGCCCG TGATCTTTCC TAAACAAGCC 
TTTGACCAGG TTCTGCAGGA TAGAAACCAC AGTTCGTTTT TAGGTTACTC TGTGGCTGCA 
ATTTCTACTG AAGACGGTGT CCATTTTGTT GCTGGTGCTC CTCGAGCAAA TTATACTGGC 
CAGATAGTGT TGTACAGCGT TAACAAGCAA GGCAATGTGA CCGTGATTCA GTCTCACAGA 
GGGGACCAGA TTGGCTCCTA TTTTGGCAGT GTGCTGTGCT CAGTTGATGT AGATAAAGAC 
ACCATTACAG ACGTGCTCCT GGTAGGTGCT CCTACATACA TGAACGACCT CAAGAAAGAA 
GAGGGAAAAG TCTACCTATT TACCATCACA AAGGGCATCT TGAATCAGCA CCAGTTTCTT 
GAAGGGCCAG AAGGCACTGG AAATGCTCGG TTTGGTTCAG CAATTGCAGC CCTGTCAGAC 
ATCAACATGG ATGGCTTTAA TGATGTGATT GTCGGTTCAC CTGTAGAGAA TGAGAACTCT 
GGAGCTGTGT ACATTTACAA TGGTCACCAG GGTACCATTC GCACCAAGTA CTCCCAGAAA 
ATCCTTGGGT CCAATGGAGC CTTTAGGAGA CATCTCCAGT TCTTTGGAAG GTCCCTGGAT 
GGCTATGGTG ATTTAAATGG GGATTCCATC ACTGATGTAT CCATTGGTGC TTTGGGGCAA 
GTGATTCAAC TCTGGTCACA AAGCATTGCT GACGTGGCCA TAGAAGCTTT GTTCACTCCA 
GACAAAATCA CTTTGCTCAA CAAGGATGCT AAGATAACCC TAAAGCTCTG CTTCAGAGCA 
GAGTTTAGAC CTGCTGGGCA AAACAATCAA GTAGCCATCC TGTTTAACAT GACGCTTGAT 
GCGGACGGAC ATTCATCCAG GGTAACCTCC AGGGGGGTGT TCAGAGAAAA CAGTGAGCGA 
TTCTTGCAGA AGAATATGGT GGTAAACGAA GTGCAGAAGT GTTCTGAGCA CCACATTAGC 
ATACAGAAGC CCTCTGATGT TGTCAACCCT TTGGATCTGC GTGTGGACAT CAGTTTGGAA 
AACCCAGGCA CTAGCCCTGC CCTCGAAGCC TATTCTGAAA CTGTCAAAGT CTTCAGTATC 
CCTTTCTATA AGGAGTGTGG CAGCGATGGA ATTTGCATCT CTGACCTGAT CCTGGATGTC 
CAACAGCTGC CAGCCATTCA AACTCAATCC TTTATTGTCA GTAACCAAAA CAAGAGGTTA 
ACATTTTCAG TCATCCTGAA AAACAGAGGG GAAAGTGCAT ACAACACTGT GGTCCTGGCC 
GAGTTTTCTG AGAACTTGTT TTTTGCTTCT TTCTCCATGC CGGTCGATGG AACAGAAGTA 
ACATGTGAGG TTGGTTCATC GCAGAAATCT GTTACCTGTG ATGTGGGATA CCCTGCCTTA 
AAGAGTGAAC AGCAGGTGAC TTTTACCATT AACTTCGACT TTAATCTTCA AAACCTCCAG 
AACCAGGCGG CCATCAATTT CCAAGCCTTC AGTGAGAGCC AAGAAACAAA CAAAGCAGAC 
AATTCGGTCA GTCTCACGAT TCCTCTCCTG TATGATGCCG AACTTCACTT AACCCGATCC 
ACCAACATCA ACTTCTATGA GATCTCTTCG GATGAGAACG CTCCTTCTGT CATCAAGAGT 
GTCGAAGATA TTGGTCCTAA ATTCATCTTC TCCCTCAAGG TAACAGCCGG AAGTGCCCCA 
GTGAGCATGG CATTGGTGAC TATCCACATT CCTCAGTACA CCAAGGAAAA GAACCCACTC 
CTGTATCTGA CTGGGATACA AACAGACCAG GCTGGCGACA TCAGCTGCAC AGCAGAAATA 
AATCCACTCA AGCTACCACA CACCGCCCCT TCTGTATCTT TCAAGAATGA AAACTTCCGG 
CATACGAAAG AATTGGACTG CAGAACCACT TCCTGCAGTA ACATCACCTG CTGGCTGAAA 
GACCTTCACA TGAAAGCAGA GTACTTCATC AATGTGACAA CCAGAGTTTG GAACAGGACC 
TTTGCTGCTT CGACTTTCCA GACTGTGCAG CTGACAGCAG CGGCAGAGAT CGATACACAT 
AACCCTCAGC TCTTCGTGAT TGAGGAAAAT GCTGTCACGA TTCCCCTCAT GATAATGAAA 
CCCACGGAGA AAGCAGAAGT ACCGACAGGG GTTATCATAG GCAGCATAAT TGCGGGAATC 
CTTTTGCTGT TGGCTATGAC TGCAGGTTTG TGGAAGCTCG GCTTCTTCAA AAGACAATAT 
AAGAAAATGG GCCAAAATCC AGATGAGATG GATGAGACCA CAGAACTCAA CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene and Protein Expression Profiles in a Mouse Model of Collagen-Induced Arthritis.
International journal of medical sciences15(1)77-85(2018)
Gwon SY,Rhee KJ,Sung HJ

The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.
Cell reports19(2)351-363(2017 Apr)
Ha T,Moon KH,Dai L,Hatakeyama J,Yoon K,Park HS,Kong YY,Shimamura K,Kim JW

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Itga2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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