Gene Symbol | IL7R |
Entrez Gene ID | 16197 |
Full Name | interleukin 7 receptor |
Synonyms | CD127,IL-7Ralpha |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome | |
Summary | Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]. |