Gene Symbol | Il18rap |
Entrez Gene ID | 16174 |
Full Name | interleukin 18 receptor accessory protein |
Synonyms | AcPL,IL-18R-beta,IL-18RAcP,IL-18Rbeta,IL-1RAcPL |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | Interleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. The encoded protein is an accessory subunit of the receptor for interleukin-18 and mediates signaling through this cytokine. Mice lacking this gene exhibit a defective cell-mediated immune response. [provided by RefSeq, Jan 2014]. |