Igf2r cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Igf2r
Entrez Gene ID	16004
Full Name	insulin-like growth factor 2 receptor
Synonyms	AI661837,CD222,CI-MPR,M6P/IGF2R,Mpr300
General protein information	Preferred Names insulin-like growth factor 2 receptor Names cation-independent mannose-6-phosphate receptor 300 kDa mannose 6-phosphate receptor CI Man-6-P receptor IGF-II receptor IGF-II/CI-MPR M6P/IGF2 receptor M6PR MPR 300 cation-independent MPR insulin-like growth factor II receptor mannose-6-phosphate receptor, cation independent
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 A1\|17 8.64 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010515.2	NP_034645.2	cation-independent mannose-6-phosphate receptor precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	IGF2R	NP_776777.1
Xenopus tropicalis (tropical clawed frog)	igf2r	XP_002933917.2
Mus musculus (house mouse)	Igf2r	NP_034645.2
Danio rerio (zebrafish)	igf2r	NP_001034716.1
	IGF2R	XP_002804004.1
Canis lupus familiaris (dog)	IGF2R	NP_001116074.1
Pan troglodytes (chimpanzee)	IGF2R	XP_003311618.2
Homo sapiens (human)	IGF2R	NP_000867.2
Rattus norvegicus (Norway rat)	Igf2r	NP_036888.1
Gallus gallus (chicken)	IGF2R	NP_990301.1

Gene Ontology
Bibliography

Related articles in PubMed

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.
Segura-Bayona S, Knobel PA, Gonz?lez-Bur?n H, Youssef SA, Pe?a-Blanco A, Coyaud ?, L?pez-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH
Cell death and differentiation24(11)1872-1885(2017 Nov)

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.
Andergassen D, Dotter CP, Wenzel D, Sigl V, Bammer PC, Muckenhuber M, Mayer D, Kulinski TM, Theussl HC, Penninger JM, Bock C, Barlow DP, Pauler FM, Hudson QJ
eLife6(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Selective M6PR down-regulation has a critical role in CD8(+) T cell survival.
Title: Differential expression of mannose-6-phosphate receptor regulates T cell contraction.

Expression of imprinted gene Igf2r was unregulated in haploid androgenetic/gynogenetic blastocysts.
Title: Analysis of imprinted gene expression and implantation in haploid androgenetic mouse embryos.

that an elevation in IGF-II receptor levels can influence the expression profiles of transcripts as well as proteins that are involved in AD pathogenesis.
Title: Overexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathology.

DNA methylation changes were noted in the Igf2r gene during chronic cystitis in a murine model.
Title: Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.

Airn expression is both necessary and sufficient to silence Igf2r throughout embryonic stem cell differentiation.
Title: Imprinted Igf2r silencing depends on continuous Airn lncRNA expression and is not restricted to a developmental window.

The following Igf2r gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Igf2r cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14966	NM_010515.2 Latest version!	Mus musculus insulin-like growth factor 2 receptor (Igf2r), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	30	$1826.30 $2609.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Igf2r ( NM_010515.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034645.2 Mus musculus insulin-like growth factor 2 receptor (Igf2r), mRNA.

Price & Availability↑

CloneID	OMu14966
Clone ID Related Accession (Same CDS sequence)	NM_010515.2
Accession Version	NM_010515.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	cation-independent mannose-6-phosphate receptor precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116804.22, BB865604.1, AC167817.4, CN530622.1, CK639250.1, CF167933.1, CA324933.1, CN461279.1, CD545656.1, BQ900123.1, AK053045.1 and BP757292.1. On Mar 20, 2007 this sequence version replaced NM_010515.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC150817.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## imprinted gene :: PMID: 19141673 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGGGCCG TTCAGCTGGG ACCGGTGCCC TCCGGGCCGC GCGTCGCGCT CCTGCCGCCG 
CTCCTGCTGC TGCTGCTCCT GGCGGCCGCG GGCTCCGCGC AGGCCCAGGC CGTCGACTTG 
GACGCCCTGT GCAGTTACAC ATGGGAAGCT GTTGACTCCA AAAACAATGC AGTTTATAAG 
ATCAACGTCT GTGGAAATGT GGGTATTTCC AGCTGTGGGC CTACAAGTGC TATCTGTATG 
TGTGACCTAA AGACAGAGAA CTGCCGCTCA GTGGGTGACT CACTTTTGAG AAGTTCAGCC 
AGATCACTCC TGGAATTCAA CACCACTATG GGCTGCCAGC CTTCAGATTC ACAGCACAGA 
ATCCAGACTA GCATTACATT TCTGTGTGGG AAGACCCTGG GAACTCCTGA ATTTGTAACT 
GCCACAGACT GTGTGCATTA CTTTGAATGG AGGACTACTG CAGCCTGCAA GAAAGACATA 
TTTAAAGCTG ATAAGGAGGT ACCATGCTAT GCATTTGATG ACAAGTTACA GAAGCATGAT 
TTAAACCCAC TGATCAAGCT AAATGGTGGC TATCTGGTAG ATGATTCTGA TCCTGACACG 
TCTCTGTTCA TCAACGTGTG TAGAGACATA GACTCCCTTC GGGACCCCAG CACACAGCTG 
AGAGTCTGTC CTGCTGGCAC TGCTGCCTGT CTGCTGAAGG GGAACCAGGC ATTTGACGTT 
GGCCGACCCA AGGAGGGGCT GAAGCTGTTG AGCAAGGACA GGCTCGTTCT GACTTATGTG 
AAGGAAGAGG GAGAAAAGCC AGACTTCTGT AATGGTCACA GCCCTGCAGT GACAGTAACA 
TTTGTGTGCC CATCTGAGCG GAGAGAGGGT ACCATTCCTA AACTCACTGC CAAGTCCAAC 
TGCCGTTATG AAGTTGAGTG GATCACCGAG TATGCCTGCC ACAGAGATTA CCTGCAAAGT 
GAGAGCTGCT CCCTCAGCAG TGAGCAGCAT GATATTACTA TTGACCTTAG TCCCTTGGCC 
CAATATGGAG GGTCCCCCTA TGTTTCTGAT GGAAGAGAAT ATACGTTTTT TATCAATGTC 
TGTGGGGACA CAAAGGTCTC ACTCTGTAAT AACAAAGAGG CTGCTGTTTG TCAAGAGAAA 
AAGGCGGATT CCACTCAAGT CAAAATAGCA GGAAGACACC AGAACCAGAC ACTCCGGTAC 
TCAGATGGAG ACCTCACCCT CATCTATTCT GGAGGTGATG AGTGTAGCTC TGGCTTCCAG 
AGGATGAGTG TCATAAACTT TGAGTGCAAC AAAACTGCAG GTAAGGATGG GAGAGGAGAG 
CCTGTGTTCA CAGGTGAGGT GGACTGCACC TACTTCTTCA CATGGGACAC TAAATACGCC 
TGCATCAAAG AGAAGGAAGA CCTCCTCTGC GGGGCCATCA ATGGCAAGAA ACGCTATGAC 
CTGTCTGTGT TGGCTCGTCA CTCAGAATCA GAACAGAATT GGGAAGCAGT GGATGGCAGC 
CAGGCAGAAT CAGAAAAGTA TTTCTTCATC AACGTCTGTC ACCGGGTGCT GCAGGAGGGG 
AAGGCCAGGA ACTGTCCTGA AGATGCTGCT GTGTGCGCTG TGGATAAGAA TGGGAGTAAA 
AACCTTGGAA AATTTGTCTC TTCTCCTACA AAAGAGAAAG GACACATACA GCTCTCTTAC 
ACTGATGGTG ATGACTGTGG CAGTGATAAG AAAATATCAA CTAACATCAC ACTTGTGTGC 
AAACCAGGTG ATCTAGAAAG TGCTCCAGTG CTAAGAGCTG CAAGATCTGA TGGCTGCTTC 
TATGAGTTTG AGTGGCATAC GGCTGCTGCC TGTGTACTGT CGAAGACAGA AGGAGAGAAC 
TGCACGGTCC TTGATGCCCA GGCAGGGTTT TCCTTTGATT TGTCACTCCT CACGAAGAAG 
AATGGTGCAT ATAAAGTTGA GACAGAGAAG TATGACTTCT ACATAAATGT TTGTGGCCCT 
GTATCCATGG ATCCTTGTCA GTCAAACTCG GGGGCCTGCC AGGTAGCGAA AAGTGGTAAG 
TCTTGGAACT TGGGGCTGAG TAGTACTAAG CTCACCTACT ACGACGGAAT GATCCAGCTG 
AGCTACAGGA ACGGCACTCC CTATAACAAT GAAAAGCACA CACCGAGAGC CACACTGATT 
ACCTTCCTCT GTGACCGTGA CGCTGGAGTG GGCTTCCCAG AATATCAGGA AGAGGACAAC 
TCTACCTACA ACTTCCGGTG GTACACCAGT TATGCCTGCC CAGAAGAACC CCTGGAGTGC 
ATGGTGACAG ACCCCTCCAT GATGGAACAG TATGACCTCT CCAGTCTAGT GAAGTCTGAA 
GGTGGCTCTG GAGGAAACTG GTATGCTATG GAAAACTCCC GGGAACATGT TACACGGAGG 
AAATACTACC TCAATGTGTG TCGGCCTCTG AATCCTGTGC CAGGCTGCGA TCGATATGCA 
TCTGCTTGCC AGATGAAATA TGAAAATCAT GAGGGCTCCT TGGCAGAGAC TGTATCCATC 
AGTAACTTGG GAGTTGCAAA GATAGGCCCT GTGGTGGAGG AGAGTGGCAG CCTCCTCTTA 
GAGTATGTGA ACGGCTCTGC TTGCACCACC AGTGATGGCC AGCTCACCAC CTACAGCACC 
AGGATCCATC TTGTCTGTGG TCGAGGATTT ATGAACTCCC ATCCCATATT CACTTTCAAC 
TGGGAATGTG TGGTCAGTTT CTTGTGGAAC ACGGAGGCTG CCTGCCCTAT CCAGACAATC 
ACAGAAACAG ACCAGGCTTG CTCAATAAGG GACCCCAGCA GTGGGTTTGT GTTTAATCTT 
AGCCCACTCA ACGATTCTGC TCAAGGACAT GTGGTCTTAG GCATCGGAAA GACTTTTGTG 
TTCAATATCT GTGGTGCAAT GCCTGCCTGT GGAACGGTTG CGGGGAAGCC AGCCTATGGC 
TGCGAGGCCG AAACTCAGAT AGAAGATATT AAGGACCTAA GGCCACAAAG GCCGGTCGGG 
ATGGAGAGGA GCCTCCAGTT GTCTGCCGAG GGATTCCTCA CTCTGACCTA CAAGGGCTCT 
TCTCCCTCTG ACAGAGGCAC AGCATTCATC ATCCGTTTTA TTTGCAACGA TGACATTTAC 
CCAGGAGCCC CCAAATTCCT GCATCAGGAC ATTGACTCCA CACGAGGGAT CCGGAACACT 
TACTTTGAGT TTGAAACTGC ATTGGCTTGT ACTCCTTCTC TAGTGGATTG TCAAGTGACT 
GACCCAGCTG GGAACGAGTA TGACTTGAGC GCCCTGAGCA TGGTCAGGAA GCCATGGACT 
GCCGTGGACA CGTCTGCATA CGGGAAGAGG AGGCACTTCT ACCTGAGTGT CTGCAACCCT 
CTGCCTTATA TCCCTGGCTG CCACGGCATT GCATTGGGGT CCTGCATGGT GTCAGAAGAC 
AACAGTTTTA ACTTGGGTGT GGTGCAGATC AGTCCTCAAG CTACTGGAAA TGGGTCTCTC 
AGCATCCTGT ACGTGAATGG GGACAGATGT GGGGACCAGC GCTTCTCCAC CAGGATCGTG 
TTCGAGTGTG CCCAGACGTC GGGCTCACCT ATGTTCCAGT TCGTGAACAA CTGTGAGTAT 
GTGTTTGTGT GGCGAACAGT GGAGGCCTGC CCTGTGATCA GAGAGGAAGG AGACAACTGC 
CAGGTGAAGG ACCCCAGGCA TGGCAATTTG TATGACCTGA AGCCCCTGGG CCTCAATGAC 
ACCATCGTCA GTGTTGGCGA GTACACCTAC TACTTGCGGG TCTGCGGGAA GCTGTCATCA 
GATGTCTGCT CTGCCCATGA CGGATCCAAG GCAGTCTCAT CATGCCAGGA AAAGAAAGGA 
CCACAGGGAT TCCAGAAAGT GGCAGGACTC CTTAGCCAGA AGCTGACTTT CGAAAACGGA 
CTGTTGAAAA TGAACTATAC TGGGGGGGAT ACCTGCCATA AGGTGTATCA GCGCTCCACA 
ACCATCTATT TCTACTGTGA CCGGACTACA CAGAAGCCAG TGTTTCTGAA GGAAACTTCG 
GACTGCTCCT ATATGTTTGA GTGGCGAACA CAGTATGCCT GCCCACCTTT CAATGTGACA 
GAGTGTTCTG TCCAGGATGC GGCTGGCAAC TCCATTGACC TCTCCTCACT GTCAAGGTAC 
AGTGACAACT GGGAGGCTGT GACCAGGACA GGGGCCACTG AGCATTACCT CATCAATGTA 
TGCAAGTCTC TGTCTCCACA CGCTGGCACA GAGCCATGCC CTCCAGAGGC AGCTGTTTGT 
CTGCTGAATG GCTCTAAGCC TGTGAACCTT GGCAAGGTGA GGGATGGCCC TCAGTGGACA 
GACGGTGTGA CTGTCCTGCA GTATGTGGAT GGTGACTTGT GCCCAGACAA AATTCGGAGA 
AGGTCAACCA TTATTCGCTT CACCTGCAGT GACAACCAAG TGAACTCCAG GCCCCTTTTC 
ATCAGTGCTG TTCAGGACTG TGAGTACACC TTCTCCTGGC CCACCCCTTC TGCCTGTCCT 
GTGAAGAGCA ACACACATGA TGACTGCCAA GTCACCAACC CCAGCACAGG CCACCTGTTT 
GACCTGAGCT CCTTAAGTGG CAGAGCTGGT ATCAATGCCT CCTACAGCGA GAAGGGGCTG 
GTCTTCATGA GCATCTGTGA GGAGAATGAG AACTGTGGCC CCGGAGTAGG GGCCTGCTTT 
GGACAGACGA GGATCAGTGT GGGCAAGGCC AGCAAGAGGC TGAGCTACAA GGACCAAGTC 
CTGCAGCTGG TGTATGAGAA TGGGTCCCCA TGCCCTTCCC TGTCAGACCT GAGGTACAAG 
AGTGTCATCA GCTTTGTGTG CCGGCCTGAG GCTGGACCTA CCAACAGGCC GATGCTCATC 
TCCTTGGACA AGCAGACGTG CACACTCTTC TTCTCCTGGC ACACACCCCT GGCCTGTGAG 
CAAGCGACGG AGTGTACTGT GCGGAATGGA AGCTCGATTA TTGACCTGTC CCCTCTCATC 
CACCGCACTG GTGGCTACGA AGCATACGAT GAAAGTGAGG ATGACACCTC TGACACCACC 
CCTGACTTCT ATATCAACAT CTGCCAGCCA CTGAATCCCA TGCACGGAGT GCCCTGCCCT 
GCAGGTGCCT CAGTATGCAA AGTTCCTGTG GACGGGCCCC CTATAGATAT TGGCAGAGTC 
ACAGGCCCTC CAATATTCAA TCCTGTGGCG AATGAAGTCT ACCTGAACTT TGAGAGCAGC 
ACTCATTGCT TAGCCGACAG ATATATGAAC TACACCTCAC TCATCACATT TCACTGCAAG 
AGAGGAGTCA GCATGGGAAC TCCTAAGCTG ATAAGGACCA ATGACTGCGA CTTTGTGTTT 
GAGTGGGAGA CTCCGATTGT CTGTCCTGAC GAAGTGAAGA CACAGGGTTG TGCTGTAACA 
GATGAGCAGC TGCTCTATAG CTTCAACCTG ACCAGCCTTT CCACAAGCAC TTTCAAGGTT 
ACTCGGGATG CCCGCACATA CAGTATAGGG GTGTGCACAG CAGCAGCTGG CTTAGGCCAG 
GAAGGCTGCA AGGATGGCGG TGTCTGTCTG CTCTCTGGGA ACAAAGGAGC TTCTTTTGGG 
CGCCTTGCAT CGATGCAGCT GGATTACAGG CACCAAGATG AAGCAGTCAT TCTGAGTTAT 
GTGAATGGTG ATCCTTGCCC TCCAGAAACG GATGATGGCG AGCCCTGTGT CTTCCCCTTC 
ATTTACAAAG GGAAGAGCTA TGATGAATGT GTATTAGAGG GACGAGCGAA ACTGTGGTGT 
AGCAAAACTG CAAATTATGA TCGTGACCAC GAGTGGGGCT TCTGCAGACA GACCAACAGC 
TACCGGATGT CTGCGATCAT ATTTACGTGT GATGAAAGTG AAGATATTGG GAGACCACAA 
GTGTTCAGTG AAGATCGTGG GTGTGAGGTG ACATTTGAGT GGAAGACAAA AGTTGTCTGC 
CCTCCAAAGA AGATGGAGTG CAAGTTTGTT CAGAAGCATA AGACCTATGA CTTGCGACTG 
CTCTCATCCC TCACGGGGTC CTGGGACTTT GTGCATGAAG GAAACTCGTA CTTTATCAAT 
CTGTGCCAAA GAGTATACAA AGGTCCCCTG GACTGCTCTG AAAGAGCCAG CATTTGCAAG 
AAGAGTGCCA CTGGTCAAGT CCAGGTTTTG GGGCTTGTTC ATACACAAAA ATTGGAAGTC 
ATAGATGAAA CGGTCATTGT TACTTACTCG AAAGGCTATC CTTGTGGTGG GAATAAGACT 
GCATCGTCTG TAATCGAATT GACCTGTGCG AAGACTGTGG GCAGGCCTGC ATTCAAGAGG 
TTTGACAGTG TCAGCTGCAC CTACTACTTT TACTGGTACT CACGGGCTGC CTGCGCGGTG 
AGGCCTCAGG AGGTGACCAT GGTGAACGGA ACGCTCACCA ACCCTGTGAC CGGCAAGAGC 
TTCAGCCTCG GCGAGATTTA TTTTAAGCTC TTCAGCGCCT CTGGAGACAT GAGGACCAAT 
GGGGACAACT ACCTGTATGA AATCCAGCTC TCCTCCATCA CCAGCTCTTC TTACCCTGCA 
TGCGCTGGTG CCAACATCTG CCAGGTGAAG CCCAATGACC AGCATTTCAG CAGGAAAGTA 
GGCACCTCTG ACATGACCAA GTACTACGTC CAAGATGGAG ATCTGGATGT GGTGTTTACC 
TCTTCCTCCA AGTGTGGGAA AGATAAGACC AAGTCTGTTT CTTCCACCAT CTTCTTCCAC 
TGTGACCCTC TGGTGAAGGA TGGGATCCCA GAGTTCAGCC ACGAGACCGC TGACTGCCAG 
TACCTGTTCT CCTGGTACAC TTCAGCTGTG TGTCCTCTGG GTGTGGACTT TGAGGATGAG 
AGCGCAGGGC CAGAGTATAA AGGACTCTCA GAGCGGAGTC AGGCTGTTGG GGCAGTCCTC 
AGTCTTCTCC TGGTGGCGCT GACTGGCTGC TTGCTGGCCT TACTGCTGCA TAAGAAGGAG 
AGAAGGGAAA CTGTGATAAA CAAGCTGACC AGCTGCTGCA GAAGAAGCTC GGGCGTGTCC 
TACAAGTACT CAAAGGTCAG CAAGGAGGAG GAGACAGATG AGAATGAGAC AGAATGGCTG 
ATGGAAGAGA TCCAGGTGCC AGCCCCAAGA CTAGGCAAGG ACGGGCAAGA AAATGGCCAT 
ATCACCACCA AGGCGGTGAA AGCAGAAGCT CTCTCGTCCC TGCATGGGGA CGACCAGGAC 
AGTGAGGATG AGGTCCTGAC CGTTCCAGAG GTGAAAGTTC ACTCAGGCCG AGGAGCGGAG 
GTGGAAAGCT CACAGCCCCT GAGAAACCCA CAGCGCAAGG TCCTGAAGGA AAGGGAGGGT 
GAGAGGCTGG GGCTGGTCCG AGGTGAGAAG GCCAGAAAAG GGAAGTTCAG ACCCGGACAG 
CGCAAGCCAA CAGCCCCTGC CAAGCTGGTG TCCTTCCATG ATGACAGCGA CGAAGACCTC 
TTACACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034645.2
CDS	174..7625
Translation	MRAVQLGPVPSGPRVALLPPLLLLLLLAAAGSAQAQAVDLDALCSYTWEAVDSKNNAVYKINVCGNVGISSCGPTSAICMCDLKTENCRSVGDSLLRSSARSLLEFNTTMGCQPSDSQHRIQTSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKDIFKADKEVPCYAFDDKLQKHDLNPLIKLNGGYLVDDSDPDTSLFINVCRDIDSLRDPSTQLRVCPAGTAACLLKGNQAFDVGRPKEGLKLLSKDRLVLTYVKEEGEKPDFCNGHSPAVTVTFVCPSERREGTIPKLTAKSNCRYEVEWITEYACHRDYLQSESCSLSSEQHDITIDLSPLAQYGGSPYVSDGREYTFFINVCGDTKVSLCNNKEAAVCQEKKADSTQVKIAGRHQNQTLRYSDGDLTLIYSGGDECSSGFQRMSVINFECNKTAGKDGRGEPVFTGEVDCTYFFTWDTKYACIKEKEDLLCGAINGKKRYDLSVLARHSESEQNWEAVDGSQAESEKYFFINVCHRVLQEGKARNCPEDAAVCAVDKNGSKNLGKFVSSPTKEKGHIQLSYTDGDDCGSDKKISTNITLVCKPGDLESAPVLRAARSDGCFYEFEWHTAAACVLSKTEGENCTVLDAQAGFSFDLSLLTKKNGAYKVETEKYDFYINVCGPVSMDPCQSNSGACQVAKSGKSWNLGLSSTKLTYYDGMIQLSYRNGTPYNNEKHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECMVTDPSMMEQYDLSSLVKSEGGSGGNWYAMENSREHVTRRKYYLNVCRPLNPVPGCDRYASACQMKYENHEGSLAETVSISNLGVAKIGPVVEESGSLLLEYVNGSACTTSDGQLTTYSTRIHLVCGRGFMNSHPIFTFNWECVVSFLWNTEAACPIQTITETDQACSIRDPSSGFVFNLSPLNDSAQGHVVLGIGKTFVFNICGAMPACGTVAGKPAYGCEAETQIEDIKDLRPQRPVGMERSLQLSAEGFLTLTYKGSSPSDRGTAFIIRFICNDDIYPGAPKFLHQDIDSTRGIRNTYFEFETALACTPSLVDCQVTDPAGNEYDLSALSMVRKPWTAVDTSAYGKRRHFYLSVCNPLPYIPGCHGIALGSCMVSEDNSFNLGVVQISPQATGNGSLSILYVNGDRCGDQRFSTRIVFECAQTSGSPMFQFVNNCEYVFVWRTVEACPVIREEGDNCQVKDPRHGNLYDLKPLGLNDTIVSVGEYTYYLRVCGKLSSDVCSAHDGSKAVSSCQEKKGPQGFQKVAGLLSQKLTFENGLLKMNYTGGDTCHKVYQRSTTIYFYCDRTTQKPVFLKETSDCSYMFEWRTQYACPPFNVTECSVQDAAGNSIDLSSLSRYSDNWEAVTRTGATEHYLINVCKSLSPHAGTEPCPPEAAVCLLNGSKPVNLGKVRDGPQWTDGVTVLQYVDGDLCPDKIRRRSTIIRFTCSDNQVNSRPLFISAVQDCEYTFSWPTPSACPVKSNTHDDCQVTNPSTGHLFDLSSLSGRAGINASYSEKGLVFMSICEENENCGPGVGACFGQTRISVGKASKRLSYKDQVLQLVYENGSPCPSLSDLRYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATECTVRNGSSIIDLSPLIHRTGGYEAYDESEDDTSDTTPDFYINICQPLNPMHGVPCPAGASVCKVPVDGPPIDIGRVTGPPIFNPVANEVYLNFESSTHCLADRYMNYTSLITFHCKRGVSMGTPKLIRTNDCDFVFEWETPIVCPDEVKTQGCAVTDEQLLYSFNLTSLSTSTFKVTRDARTYSIGVCTAAAGLGQEGCKDGGVCLLSGNKGASFGRLASMQLDYRHQDEAVILSYVNGDPCPPETDDGEPCVFPFIYKGKSYDECVLEGRAKLWCSKTANYDRDHEWGFCRQTNSYRMSAIIFTCDESEDIGRPQVFSEDRGCEVTFEWKTKVVCPPKKMECKFVQKHKTYDLRLLSSLTGSWDFVHEGNSYFINLCQRVYKGPLDCSERASICKKSATGQVQVLGLVHTQKLEVIDETVIVTYSKGYPCGGNKTASSVIELTCAKTVGRPAFKRFDSVSCTYYFYWYSRAACAVRPQEVTMVNGTLTNPVTGKSFSLGEIYFKLFSASGDMRTNGDNYLYEIQLSSITSSSYPACAGANICQVKPNDQHFSRKVGTSDMTKYYVQDGDLDVVFTSSSKCGKDKTKSVSSTIFFHCDPLVKDGIPEFSHETADCQYLFSWYTSAVCPLGVDFEDESAGPEYKGLSERSQAVGAVLSLLLVALTGCLLALLLHKKERRETVINKLTSCCRRSSGVSYKYSKVSKEEETDENETEWLMEEIQVPAPRLGKDGQENGHITTKAVKAEALSSLHGDDQDSEDEVLTVPEVKVHSGRGAEVESSQPLRNPQRKVLKEREGERLGLVRGEKARKGKFRPGQRKPTAPAKLVSFHDDSDEDLLHI

Target ORF information:

RefSeq Version	NM_010515.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus insulin-like growth factor 2 receptor (Igf2r), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010515.2

ORF Insert Sequence:

ATGCGGGCCG TTCAGCTGGG ACCGGTGCCC TCCGGGCCGC GCGTCGCGCT CCTGCCGCCG 
CTCCTGCTGC TGCTGCTCCT GGCGGCCGCG GGCTCCGCGC AGGCCCAGGC CGTCGACTTG 
GACGCCCTGT GCAGTTACAC ATGGGAAGCT GTTGACTCCA AAAACAATGC AGTTTATAAG 
ATCAACGTCT GTGGAAATGT GGGTATTTCC AGCTGTGGGC CTACAAGTGC TATCTGTATG 
TGTGACCTAA AGACAGAGAA CTGCCGCTCA GTGGGTGACT CACTTTTGAG AAGTTCAGCC 
AGATCACTCC TGGAATTCAA CACCACTATG GGCTGCCAGC CTTCAGATTC ACAGCACAGA 
ATCCAGACTA GCATTACATT TCTGTGTGGG AAGACCCTGG GAACTCCTGA ATTTGTAACT 
GCCACAGACT GTGTGCATTA CTTTGAATGG AGGACTACTG CAGCCTGCAA GAAAGACATA 
TTTAAAGCTG ATAAGGAGGT ACCATGCTAT GCATTTGATG ACAAGTTACA GAAGCATGAT 
TTAAACCCAC TGATCAAGCT AAATGGTGGC TATCTGGTAG ATGATTCTGA TCCTGACACG 
TCTCTGTTCA TCAACGTGTG TAGAGACATA GACTCCCTTC GGGACCCCAG CACACAGCTG 
AGAGTCTGTC CTGCTGGCAC TGCTGCCTGT CTGCTGAAGG GGAACCAGGC ATTTGACGTT 
GGCCGACCCA AGGAGGGGCT GAAGCTGTTG AGCAAGGACA GGCTCGTTCT GACTTATGTG 
AAGGAAGAGG GAGAAAAGCC AGACTTCTGT AATGGTCACA GCCCTGCAGT GACAGTAACA 
TTTGTGTGCC CATCTGAGCG GAGAGAGGGT ACCATTCCTA AACTCACTGC CAAGTCCAAC 
TGCCGTTATG AAGTTGAGTG GATCACCGAG TATGCCTGCC ACAGAGATTA CCTGCAAAGT 
GAGAGCTGCT CCCTCAGCAG TGAGCAGCAT GATATTACTA TTGACCTTAG TCCCTTGGCC 
CAATATGGAG GGTCCCCCTA TGTTTCTGAT GGAAGAGAAT ATACGTTTTT TATCAATGTC 
TGTGGGGACA CAAAGGTCTC ACTCTGTAAT AACAAAGAGG CTGCTGTTTG TCAAGAGAAA 
AAGGCGGATT CCACTCAAGT CAAAATAGCA GGAAGACACC AGAACCAGAC ACTCCGGTAC 
TCAGATGGAG ACCTCACCCT CATCTATTCT GGAGGTGATG AGTGTAGCTC TGGCTTCCAG 
AGGATGAGTG TCATAAACTT TGAGTGCAAC AAAACTGCAG GTAAGGATGG GAGAGGAGAG 
CCTGTGTTCA CAGGTGAGGT GGACTGCACC TACTTCTTCA CATGGGACAC TAAATACGCC 
TGCATCAAAG AGAAGGAAGA CCTCCTCTGC GGGGCCATCA ATGGCAAGAA ACGCTATGAC 
CTGTCTGTGT TGGCTCGTCA CTCAGAATCA GAACAGAATT GGGAAGCAGT GGATGGCAGC 
CAGGCAGAAT CAGAAAAGTA TTTCTTCATC AACGTCTGTC ACCGGGTGCT GCAGGAGGGG 
AAGGCCAGGA ACTGTCCTGA AGATGCTGCT GTGTGCGCTG TGGATAAGAA TGGGAGTAAA 
AACCTTGGAA AATTTGTCTC TTCTCCTACA AAAGAGAAAG GACACATACA GCTCTCTTAC 
ACTGATGGTG ATGACTGTGG CAGTGATAAG AAAATATCAA CTAACATCAC ACTTGTGTGC 
AAACCAGGTG ATCTAGAAAG TGCTCCAGTG CTAAGAGCTG CAAGATCTGA TGGCTGCTTC 
TATGAGTTTG AGTGGCATAC GGCTGCTGCC TGTGTACTGT CGAAGACAGA AGGAGAGAAC 
TGCACGGTCC TTGATGCCCA GGCAGGGTTT TCCTTTGATT TGTCACTCCT CACGAAGAAG 
AATGGTGCAT ATAAAGTTGA GACAGAGAAG TATGACTTCT ACATAAATGT TTGTGGCCCT 
GTATCCATGG ATCCTTGTCA GTCAAACTCG GGGGCCTGCC AGGTAGCGAA AAGTGGTAAG 
TCTTGGAACT TGGGGCTGAG TAGTACTAAG CTCACCTACT ACGACGGAAT GATCCAGCTG 
AGCTACAGGA ACGGCACTCC CTATAACAAT GAAAAGCACA CACCGAGAGC CACACTGATT 
ACCTTCCTCT GTGACCGTGA CGCTGGAGTG GGCTTCCCAG AATATCAGGA AGAGGACAAC 
TCTACCTACA ACTTCCGGTG GTACACCAGT TATGCCTGCC CAGAAGAACC CCTGGAGTGC 
ATGGTGACAG ACCCCTCCAT GATGGAACAG TATGACCTCT CCAGTCTAGT GAAGTCTGAA 
GGTGGCTCTG GAGGAAACTG GTATGCTATG GAAAACTCCC GGGAACATGT TACACGGAGG 
AAATACTACC TCAATGTGTG TCGGCCTCTG AATCCTGTGC CAGGCTGCGA TCGATATGCA 
TCTGCTTGCC AGATGAAATA TGAAAATCAT GAGGGCTCCT TGGCAGAGAC TGTATCCATC 
AGTAACTTGG GAGTTGCAAA GATAGGCCCT GTGGTGGAGG AGAGTGGCAG CCTCCTCTTA 
GAGTATGTGA ACGGCTCTGC TTGCACCACC AGTGATGGCC AGCTCACCAC CTACAGCACC 
AGGATCCATC TTGTCTGTGG TCGAGGATTT ATGAACTCCC ATCCCATATT CACTTTCAAC 
TGGGAATGTG TGGTCAGTTT CTTGTGGAAC ACGGAGGCTG CCTGCCCTAT CCAGACAATC 
ACAGAAACAG ACCAGGCTTG CTCAATAAGG GACCCCAGCA GTGGGTTTGT GTTTAATCTT 
AGCCCACTCA ACGATTCTGC TCAAGGACAT GTGGTCTTAG GCATCGGAAA GACTTTTGTG 
TTCAATATCT GTGGTGCAAT GCCTGCCTGT GGAACGGTTG CGGGGAAGCC AGCCTATGGC 
TGCGAGGCCG AAACTCAGAT AGAAGATATT AAGGACCTAA GGCCACAAAG GCCGGTCGGG 
ATGGAGAGGA GCCTCCAGTT GTCTGCCGAG GGATTCCTCA CTCTGACCTA CAAGGGCTCT 
TCTCCCTCTG ACAGAGGCAC AGCATTCATC ATCCGTTTTA TTTGCAACGA TGACATTTAC 
CCAGGAGCCC CCAAATTCCT GCATCAGGAC ATTGACTCCA CACGAGGGAT CCGGAACACT 
TACTTTGAGT TTGAAACTGC ATTGGCTTGT ACTCCTTCTC TAGTGGATTG TCAAGTGACT 
GACCCAGCTG GGAACGAGTA TGACTTGAGC GCCCTGAGCA TGGTCAGGAA GCCATGGACT 
GCCGTGGACA CGTCTGCATA CGGGAAGAGG AGGCACTTCT ACCTGAGTGT CTGCAACCCT 
CTGCCTTATA TCCCTGGCTG CCACGGCATT GCATTGGGGT CCTGCATGGT GTCAGAAGAC 
AACAGTTTTA ACTTGGGTGT GGTGCAGATC AGTCCTCAAG CTACTGGAAA TGGGTCTCTC 
AGCATCCTGT ACGTGAATGG GGACAGATGT GGGGACCAGC GCTTCTCCAC CAGGATCGTG 
TTCGAGTGTG CCCAGACGTC GGGCTCACCT ATGTTCCAGT TCGTGAACAA CTGTGAGTAT 
GTGTTTGTGT GGCGAACAGT GGAGGCCTGC CCTGTGATCA GAGAGGAAGG AGACAACTGC 
CAGGTGAAGG ACCCCAGGCA TGGCAATTTG TATGACCTGA AGCCCCTGGG CCTCAATGAC 
ACCATCGTCA GTGTTGGCGA GTACACCTAC TACTTGCGGG TCTGCGGGAA GCTGTCATCA 
GATGTCTGCT CTGCCCATGA CGGATCCAAG GCAGTCTCAT CATGCCAGGA AAAGAAAGGA 
CCACAGGGAT TCCAGAAAGT GGCAGGACTC CTTAGCCAGA AGCTGACTTT CGAAAACGGA 
CTGTTGAAAA TGAACTATAC TGGGGGGGAT ACCTGCCATA AGGTGTATCA GCGCTCCACA 
ACCATCTATT TCTACTGTGA CCGGACTACA CAGAAGCCAG TGTTTCTGAA GGAAACTTCG 
GACTGCTCCT ATATGTTTGA GTGGCGAACA CAGTATGCCT GCCCACCTTT CAATGTGACA 
GAGTGTTCTG TCCAGGATGC GGCTGGCAAC TCCATTGACC TCTCCTCACT GTCAAGGTAC 
AGTGACAACT GGGAGGCTGT GACCAGGACA GGGGCCACTG AGCATTACCT CATCAATGTA 
TGCAAGTCTC TGTCTCCACA CGCTGGCACA GAGCCATGCC CTCCAGAGGC AGCTGTTTGT 
CTGCTGAATG GCTCTAAGCC TGTGAACCTT GGCAAGGTGA GGGATGGCCC TCAGTGGACA 
GACGGTGTGA CTGTCCTGCA GTATGTGGAT GGTGACTTGT GCCCAGACAA AATTCGGAGA 
AGGTCAACCA TTATTCGCTT CACCTGCAGT GACAACCAAG TGAACTCCAG GCCCCTTTTC 
ATCAGTGCTG TTCAGGACTG TGAGTACACC TTCTCCTGGC CCACCCCTTC TGCCTGTCCT 
GTGAAGAGCA ACACACATGA TGACTGCCAA GTCACCAACC CCAGCACAGG CCACCTGTTT 
GACCTGAGCT CCTTAAGTGG CAGAGCTGGT ATCAATGCCT CCTACAGCGA GAAGGGGCTG 
GTCTTCATGA GCATCTGTGA GGAGAATGAG AACTGTGGCC CCGGAGTAGG GGCCTGCTTT 
GGACAGACGA GGATCAGTGT GGGCAAGGCC AGCAAGAGGC TGAGCTACAA GGACCAAGTC 
CTGCAGCTGG TGTATGAGAA TGGGTCCCCA TGCCCTTCCC TGTCAGACCT GAGGTACAAG 
AGTGTCATCA GCTTTGTGTG CCGGCCTGAG GCTGGACCTA CCAACAGGCC GATGCTCATC 
TCCTTGGACA AGCAGACGTG CACACTCTTC TTCTCCTGGC ACACACCCCT GGCCTGTGAG 
CAAGCGACGG AGTGTACTGT GCGGAATGGA AGCTCGATTA TTGACCTGTC CCCTCTCATC 
CACCGCACTG GTGGCTACGA AGCATACGAT GAAAGTGAGG ATGACACCTC TGACACCACC 
CCTGACTTCT ATATCAACAT CTGCCAGCCA CTGAATCCCA TGCACGGAGT GCCCTGCCCT 
GCAGGTGCCT CAGTATGCAA AGTTCCTGTG GACGGGCCCC CTATAGATAT TGGCAGAGTC 
ACAGGCCCTC CAATATTCAA TCCTGTGGCG AATGAAGTCT ACCTGAACTT TGAGAGCAGC 
ACTCATTGCT TAGCCGACAG ATATATGAAC TACACCTCAC TCATCACATT TCACTGCAAG 
AGAGGAGTCA GCATGGGAAC TCCTAAGCTG ATAAGGACCA ATGACTGCGA CTTTGTGTTT 
GAGTGGGAGA CTCCGATTGT CTGTCCTGAC GAAGTGAAGA CACAGGGTTG TGCTGTAACA 
GATGAGCAGC TGCTCTATAG CTTCAACCTG ACCAGCCTTT CCACAAGCAC TTTCAAGGTT 
ACTCGGGATG CCCGCACATA CAGTATAGGG GTGTGCACAG CAGCAGCTGG CTTAGGCCAG 
GAAGGCTGCA AGGATGGCGG TGTCTGTCTG CTCTCTGGGA ACAAAGGAGC TTCTTTTGGG 
CGCCTTGCAT CGATGCAGCT GGATTACAGG CACCAAGATG AAGCAGTCAT TCTGAGTTAT 
GTGAATGGTG ATCCTTGCCC TCCAGAAACG GATGATGGCG AGCCCTGTGT CTTCCCCTTC 
ATTTACAAAG GGAAGAGCTA TGATGAATGT GTATTAGAGG GACGAGCGAA ACTGTGGTGT 
AGCAAAACTG CAAATTATGA TCGTGACCAC GAGTGGGGCT TCTGCAGACA GACCAACAGC 
TACCGGATGT CTGCGATCAT ATTTACGTGT GATGAAAGTG AAGATATTGG GAGACCACAA 
GTGTTCAGTG AAGATCGTGG GTGTGAGGTG ACATTTGAGT GGAAGACAAA AGTTGTCTGC 
CCTCCAAAGA AGATGGAGTG CAAGTTTGTT CAGAAGCATA AGACCTATGA CTTGCGACTG 
CTCTCATCCC TCACGGGGTC CTGGGACTTT GTGCATGAAG GAAACTCGTA CTTTATCAAT 
CTGTGCCAAA GAGTATACAA AGGTCCCCTG GACTGCTCTG AAAGAGCCAG CATTTGCAAG 
AAGAGTGCCA CTGGTCAAGT CCAGGTTTTG GGGCTTGTTC ATACACAAAA ATTGGAAGTC 
ATAGATGAAA CGGTCATTGT TACTTACTCG AAAGGCTATC CTTGTGGTGG GAATAAGACT 
GCATCGTCTG TAATCGAATT GACCTGTGCG AAGACTGTGG GCAGGCCTGC ATTCAAGAGG 
TTTGACAGTG TCAGCTGCAC CTACTACTTT TACTGGTACT CACGGGCTGC CTGCGCGGTG 
AGGCCTCAGG AGGTGACCAT GGTGAACGGA ACGCTCACCA ACCCTGTGAC CGGCAAGAGC 
TTCAGCCTCG GCGAGATTTA TTTTAAGCTC TTCAGCGCCT CTGGAGACAT GAGGACCAAT 
GGGGACAACT ACCTGTATGA AATCCAGCTC TCCTCCATCA CCAGCTCTTC TTACCCTGCA 
TGCGCTGGTG CCAACATCTG CCAGGTGAAG CCCAATGACC AGCATTTCAG CAGGAAAGTA 
GGCACCTCTG ACATGACCAA GTACTACGTC CAAGATGGAG ATCTGGATGT GGTGTTTACC 
TCTTCCTCCA AGTGTGGGAA AGATAAGACC AAGTCTGTTT CTTCCACCAT CTTCTTCCAC 
TGTGACCCTC TGGTGAAGGA TGGGATCCCA GAGTTCAGCC ACGAGACCGC TGACTGCCAG 
TACCTGTTCT CCTGGTACAC TTCAGCTGTG TGTCCTCTGG GTGTGGACTT TGAGGATGAG 
AGCGCAGGGC CAGAGTATAA AGGACTCTCA GAGCGGAGTC AGGCTGTTGG GGCAGTCCTC 
AGTCTTCTCC TGGTGGCGCT GACTGGCTGC TTGCTGGCCT TACTGCTGCA TAAGAAGGAG 
AGAAGGGAAA CTGTGATAAA CAAGCTGACC AGCTGCTGCA GAAGAAGCTC GGGCGTGTCC 
TACAAGTACT CAAAGGTCAG CAAGGAGGAG GAGACAGATG AGAATGAGAC AGAATGGCTG 
ATGGAAGAGA TCCAGGTGCC AGCCCCAAGA CTAGGCAAGG ACGGGCAAGA AAATGGCCAT 
ATCACCACCA AGGCGGTGAA AGCAGAAGCT CTCTCGTCCC TGCATGGGGA CGACCAGGAC 
AGTGAGGATG AGGTCCTGAC CGTTCCAGAG GTGAAAGTTC ACTCAGGCCG AGGAGCGGAG 
GTGGAAAGCT CACAGCCCCT GAGAAACCCA CAGCGCAAGG TCCTGAAGGA AAGGGAGGGT 
GAGAGGCTGG GGCTGGTCCG AGGTGAGAAG GCCAGAAAAG GGAAGTTCAG ACCCGGACAG 
CGCAAGCCAA CAGCCCCTGC CAAGCTGGTG TCCTTCCATG ATGACAGCGA CGAAGACCTC 
TTACACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.
Cell death and differentiation24(11)1872-1885(2017 Nov)
Segura-Bayona S,Knobel PA,Gonz?lez-Bur?n H,Youssef SA,Pe?a-Blanco A,Coyaud ?,L?pez-Rovira T,Rein K,Palenzuela L,Colombelli J,Forrow S,Raught B,Groth A,de Bruin A,Stracker TH

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.
eLife6(2017 Aug)
Andergassen D,Dotter CP,Wenzel D,Sigl V,Bammer PC,Muckenhuber M,Mayer D,Kulinski TM,Theussl HC,Penninger JM,Bock C,Barlow DP,Pauler FM,Hudson QJ

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Igf2r cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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