Hoxb13 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hoxb13
Entrez Gene ID	15408
Full Name	homeobox B13
General protein information	Preferred Names homeobox B13 Names homeobox protein Hox-B13 homeo box B13
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 D\|11 59.63 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008267.3	NP_032293.1	homeobox protein Hox-B13
NM_008267.4	NP_032293.1	homeobox protein Hox-B13

Pathways from BioSystems

Homologies

Homo sapiens (human)	HOXB13	NP_006352.2
Rattus norvegicus (Norway rat)	Hoxb13	NP_001100511.1
Bos taurus (cattle)	HOXB13	XP_003587468.1
Danio rerio (zebrafish)	hoxb13a	NP_001038377.1
Mus musculus (house mouse)	Hoxb13	NP_032293.1
Gallus gallus (chicken)	HOXB13	XP_001234927.1
Pan troglodytes (chimpanzee)	HOXB13	XP_523822.1
	HOXB13	XP_001089620.1
Canis lupus familiaris (dog)	HOXB13	XP_548180.2

Gene Ontology
Bibliography

Related articles in PubMed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.
Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Wakana S, Ikawa M, Asano M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(6)2252-2266(2017 06)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H
PloS one8(10)e75754(2013)

Wnt signaling though beta-catenin is required for prostate lineage specification.
Simons BW, Hurley PJ, Huang Z, Ross AE, Miller R, Marchionni L, Berman DM, Schaeffer EM
Developmental biology371(2)246-55(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cdx and Wnt mutations and premature Hox13 expression also cause similar neural dysmorphology
Title: Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.

Hoxb13 has a negative effect on skin wound repair
Title: Persistent inflammation and angiogenesis during wound healing in K14-directed Hoxb13 transgenic mice.

Data demonstrate that FOXA1 directly regulates HOXB13 in human prostate epithelial cells, and show that this prostate-specific regulatory mechanism is conserved in mice.
Title: A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland.

Hoxb13 cis-regulatory elements provide a powerful tool to achieve androgen-independent transgene expression in the prostate and distal colon-specific expression in the gastrointestinal tract
Title: Hoxb13 regulatory elements mediate transgene expression during prostate organogenesis and carcinogenesis.

An increase of the Ala repeat above a certain length (22 Ala)in the Hoxd13 sequence, resulting in synpolydactyly, is associated with a shift in the localization of Hox13 from nuclear to cytoplasmic and aggregation.
Title: A molecular pathogenesis for transcription factor associated poly-alanine tract expansions.

The following Hoxb13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hoxb13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01633	NM_008267.4 Latest version!	Mus musculus homeobox B13 (Hoxb13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OMu01633	NM_008267.3	Mus musculus homeobox B13 (Hoxb13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hoxb13 ( NM_008267.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032293.1 Mus musculus homeobox B13 (Hoxb13), mRNA.

Price & Availability↑

CloneID	OMu01633
Clone ID Related Accession (Same CDS sequence)	NM_008267.3 , NM_008267.4
Accession Version	NM_008267.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Mus musculus(house mouse)
Product	homeobox protein Hox-B13
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL645478.15. On Nov 17, 2006 this sequence version replaced NM_008267.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013639.1, AK077273.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCCG GCAATTATGC CACCTTGGAC GGGGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCTGGAGGGG GTCGGAATCT AGTCTCCCAC TCCTCCCCAC TGGCTAGCCA TCCCGCGGCT 
CCAACGCTGA TGCCAACTGT CAACTATGCC CCCCTGGATC TGCCAGGCTC TGCAGAGCCA 
CCAAAGCAGT GCCACCCTTG TCCTGGGGTG CCTCAGGGGG CATCTCCAGC TCCTGTGCCT 
TATGGCTACT TTGGAGGCGG GTACTACTCT TGCCGAGTAT CCAGGAGCTC CCTGAAACCC 
TGTGCCCAGA CGGCCGCCCT GGCTACCTAC CCTTCGGAAA CTCCTGCACC TGGGGAGGAG 
TATCCCAGCC GTCCCACCGA GTTTGCCTTC TATCCGGGCT ACCCGGGACC ATACCAGCCT 
ATGGCCAGTT ACCTGGATGT GTCTGTGGTG CAGACCCTGG GAGCCCCCGG AGAGCCTCGC 
CACGATTCTC TGCTTCCCGT GGACAGTTAC CAGCCCTGGG CCCTGGCCGG TGGCTGGAAC 
AGCCAGATGT GTTGCCAAGG TGAACAGAAC CCACCAGGTC CATTCTGGAA AGCAGCGTTT 
GCAGAGCCCA GTGTCCAGCA CCCTCCTCCC GACGGCTGTG CCTTCCGCCG AGGCCGCAAA 
AAACGCATTC CCTATAGCAA GGGGCAGTTG CGGGAGTTGG AGCGGGAGTA TGCAGCCAAC 
AAGTTTATCA CTAAGGACAA GAGGCGCAAG ATCTCGGCAG CCACCAGCCT CTCTGAACGC 
CAGATTACCA TCTGGTTTCA GAACCGCCGG GTCAAGGAGA AGAAGGTTCT TGCCAAGGTC 
AAGACCAGCA CTACCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032293.1
CDS	83..943
Translation	MEPGNYATLDGAKDIEGLLGAGGGRNLVSHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTAALATYPSETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP

Target ORF information:

RefSeq Version	NM_008267.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus homeobox B13 (Hoxb13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008267.3

ORF Insert Sequence:

ATGGAGCCCG GCAATTATGC CACCTTGGAC GGGGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCTGGAGGGG GTCGGAATCT AGTCTCCCAC TCCTCCCCAC TGGCTAGCCA TCCCGCGGCT 
CCAACGCTGA TGCCAACTGT CAACTATGCC CCCCTGGATC TGCCAGGCTC TGCAGAGCCA 
CCAAAGCAGT GCCACCCTTG TCCTGGGGTG CCTCAGGGGG CATCTCCAGC TCCTGTGCCT 
TATGGCTACT TTGGAGGCGG GTACTACTCT TGCCGAGTAT CCAGGAGCTC CCTGAAACCC 
TGTGCCCAGA CGGCCGCCCT GGCTACCTAC CCTTCGGAAA CTCCTGCACC TGGGGAGGAG 
TATCCCAGCC GTCCCACCGA GTTTGCCTTC TATCCGGGCT ACCCGGGACC ATACCAGCCT 
ATGGCCAGTT ACCTGGATGT GTCTGTGGTG CAGACCCTGG GAGCCCCCGG AGAGCCTCGC 
CACGATTCTC TGCTTCCCGT GGACAGTTAC CAGCCCTGGG CCCTGGCCGG TGGCTGGAAC 
AGCCAGATGT GTTGCCAAGG TGAACAGAAC CCACCAGGTC CATTCTGGAA AGCAGCGTTT 
GCAGAGCCCA GTGTCCAGCA CCCTCCTCCC GACGGCTGTG CCTTCCGCCG AGGCCGCAAA 
AAACGCATTC CCTATAGCAA GGGGCAGTTG CGGGAGTTGG AGCGGGAGTA TGCAGCCAAC 
AAGTTTATCA CTAAGGACAA GAGGCGCAAG ATCTCGGCAG CCACCAGCCT CTCTGAACGC 
CAGATTACCA TCTGGTTTCA GAACCGCCGG GTCAAGGAGA AGAAGGTTCT TGCCAAGGTC 
AAGACCAGCA CTACCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hoxb13 ( NM_008267.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032293.1 Mus musculus homeobox B13 (Hoxb13), mRNA.

Price & Availability↑

CloneID	OMu01633
Clone ID Related Accession (Same CDS sequence)	NM_008267.3 , NM_008267.4
Accession Version	NM_008267.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	homeobox protein Hox-B13
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645478.15. On Feb 16, 2018 this sequence version replaced NM_008267.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ960077.1, AK077273.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCG GCAATTATGC CACCTTGGAC GGGGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCTGGAGGGG GTCGGAATCT AGTCTCCCAC TCCTCCCCAC TGGCTAGCCA TCCCGCGGCT 
CCAACGCTGA TGCCAACTGT CAACTATGCC CCCCTGGATC TGCCAGGCTC TGCAGAGCCA 
CCAAAGCAGT GCCACCCTTG TCCTGGGGTG CCTCAGGGGG CATCTCCAGC TCCTGTGCCT 
TATGGCTACT TTGGAGGCGG GTACTACTCT TGCCGAGTAT CCAGGAGCTC CCTGAAACCC 
TGTGCCCAGA CGGCCGCCCT GGCTACCTAC CCTTCGGAAA CTCCTGCACC TGGGGAGGAG 
TATCCCAGCC GTCCCACCGA GTTTGCCTTC TATCCGGGCT ACCCGGGACC ATACCAGCCT 
ATGGCCAGTT ACCTGGATGT GTCTGTGGTG CAGACCCTGG GAGCCCCCGG AGAGCCTCGC 
CACGATTCTC TGCTTCCCGT GGACAGTTAC CAGCCCTGGG CCCTGGCCGG TGGCTGGAAC 
AGCCAGATGT GTTGCCAAGG TGAACAGAAC CCACCAGGTC CATTCTGGAA AGCAGCGTTT 
GCAGAGCCCA GTGTCCAGCA CCCTCCTCCC GACGGCTGTG CCTTCCGCCG AGGCCGCAAA 
AAACGCATTC CCTATAGCAA GGGGCAGTTG CGGGAGTTGG AGCGGGAGTA TGCAGCCAAC 
AAGTTTATCA CTAAGGACAA GAGGCGCAAG ATCTCGGCAG CCACCAGCCT CTCTGAACGC 
CAGATTACCA TCTGGTTTCA GAACCGCCGG GTCAAGGAGA AGAAGGTTCT TGCCAAGGTC 
AAGACCAGCA CTACCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032293.1
CDS	128..988
Translation	MEPGNYATLDGAKDIEGLLGAGGGRNLVSHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTAALATYPSETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP

Target ORF information:

RefSeq Version	NM_008267.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus homeobox B13 (Hoxb13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008267.4

ORF Insert Sequence:

ATGGAGCCCG GCAATTATGC CACCTTGGAC GGGGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCTGGAGGGG GTCGGAATCT AGTCTCCCAC TCCTCCCCAC TGGCTAGCCA TCCCGCGGCT 
CCAACGCTGA TGCCAACTGT CAACTATGCC CCCCTGGATC TGCCAGGCTC TGCAGAGCCA 
CCAAAGCAGT GCCACCCTTG TCCTGGGGTG CCTCAGGGGG CATCTCCAGC TCCTGTGCCT 
TATGGCTACT TTGGAGGCGG GTACTACTCT TGCCGAGTAT CCAGGAGCTC CCTGAAACCC 
TGTGCCCAGA CGGCCGCCCT GGCTACCTAC CCTTCGGAAA CTCCTGCACC TGGGGAGGAG 
TATCCCAGCC GTCCCACCGA GTTTGCCTTC TATCCGGGCT ACCCGGGACC ATACCAGCCT 
ATGGCCAGTT ACCTGGATGT GTCTGTGGTG CAGACCCTGG GAGCCCCCGG AGAGCCTCGC 
CACGATTCTC TGCTTCCCGT GGACAGTTAC CAGCCCTGGG CCCTGGCCGG TGGCTGGAAC 
AGCCAGATGT GTTGCCAAGG TGAACAGAAC CCACCAGGTC CATTCTGGAA AGCAGCGTTT 
GCAGAGCCCA GTGTCCAGCA CCCTCCTCCC GACGGCTGTG CCTTCCGCCG AGGCCGCAAA 
AAACGCATTC CCTATAGCAA GGGGCAGTTG CGGGAGTTGG AGCGGGAGTA TGCAGCCAAC 
AAGTTTATCA CTAAGGACAA GAGGCGCAAG ATCTCGGCAG CCACCAGCCT CTCTGAACGC 
CAGATTACCA TCTGGTTTCA GAACCGCCGG GTCAAGGAGA AGAAGGTTCT TGCCAAGGTC 
AAGACCAGCA CTACCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(6)2252-2266(2017 06)
Naruse C,Shibata S,Tamura M,Kawaguchi T,Abe K,Sugihara K,Kato T,Nishiuchi T,Wakana S,Ikawa M,Asano M

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
PloS one8(10)e75754(2013)
Shimizu H,Kubo A,Uchibe K,Hashimoto M,Yokoyama S,Takada S,Mitsuoka K,Asahara H

Wnt signaling though beta-catenin is required for prostate lineage specification.
Developmental biology371(2)246-55(2012 Nov)
Simons BW,Hurley PJ,Huang Z,Ross AE,Miller R,Marchionni L,Berman DM,Schaeffer EM

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Hoxb13 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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