gRNAs
The following Hipk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hipk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu21093 | |
| Clone ID Related Accession (Same CDS sequence) | NM_010432.2 , NM_001301304.1 | |
| Accession Version | NM_010432.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3633bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-09 | |
| Organism | Mus musculus(house mouse) | |
| Product | homeodomain-interacting protein kinase 1 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK134408.1, AF170304.1, AC132567.3 and AW125573.1. On Oct 30, 2007 this sequence version replaced NM_010432.1. Transcript Variant: This variant (1) represents the longest transcript ans encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF170304.1, AF077658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_034562.2 |
| CDS | 284..3916 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_010432.2 |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu21093 | |
| Clone ID Related Accession (Same CDS sequence) | NM_010432.2 , NM_001301304.1 | |
| Accession Version | NM_001301304.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3633bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-09 | |
| Organism | Mus musculus(house mouse) | |
| Product | homeodomain-interacting protein kinase 1 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132567.3. On or before Aug 1, 2014 this sequence version replaced XM_006535889.1, XM_006501033.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF071070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001288233.1 |
| CDS | 174..3806 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001301304.1 |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu67951 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001301306.1 | |
| Accession Version | NM_001301306.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3498bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-09 | |
| Organism | Mus musculus(house mouse) | |
| Product | homeodomain-interacting protein kinase 1 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132567.3. Transcript Variant: This variant (3) lacks an in-frame exon in central coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF170303.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001288235.1 |
| CDS | 284..3781 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001301306.1 |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu67952 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011240024.1 | |
| Accession Version | XM_011240024.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3531bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | homeodomain-interacting protein kinase 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011238326.1 |
| CDS | 3..3533 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011240024.1 |
1 | ATGGCCTCAC AGCTGCAGGT GTTTTCGCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-?-TAK1-dependent mechanism. |
Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1. |
Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1. |
Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response. |
