Hebp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hebp1
Entrez Gene ID	15199
Full Name	heme binding protein 1
Synonyms	Hebp,p22HBP
General protein information	Preferred Names heme binding protein 1 Names heme-binding protein 1 p22 HBP
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 G1

mRNA and Protein(s)

mRNA	Protein	Name
XM_011241224.2	XP_011239526.1	heme-binding protein 1 isoform X1
NM_013546.3	NP_038574.3	heme-binding protein 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	HEBP1	NP_001025925.1
Homo sapiens (human)	HEBP1	NP_057071.2
	HEBP1	XP_001086941.1
Canis lupus familiaris (dog)	HEBP1	XP_534884.1
Pan troglodytes (chimpanzee)	HEBP1	XP_528742.2
Mus musculus (house mouse)	Hebp1	NP_038574.2
Bos taurus (cattle)	HEBP1	NP_001069453.1
Rattus norvegicus (Norway rat)	Hebp1	NP_001102121.1
Xenopus tropicalis (tropical clawed frog)	hebp1	NP_001004901.1

Gene Ontology
Bibliography

Related articles in PubMed

Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins.
Micaelo NM, Macedo AL, Goodfellow BJ, F?lix V
Journal of molecular graphics & modelling29(3)396-405(2010 Nov)

F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor.
Gao JL, Guillabert A, Hu J, Le Y, Urizar E, Seligman E, Fang KJ, Yuan X, Imbault V, Communi D, Wang JM, Parmentier M, Murphy PM, Migeotte I
Journal of immunology (Baltimore, Md. : 1950)178(3)1450-6(2007 Feb)

The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.
Dias JS, Macedo AL, Ferreira GC, Peterson FC, Volkman BF, Goodfellow BJ
The Journal of biological chemistry281(42)31553-61(2006 Oct)

SOUL in mouse eyes is a new hexameric heme-binding protein with characteristic optical absorption, resonance Raman spectral, and heme-binding properties.
Sato E, Sagami I, Uchida T, Sato A, Kitagawa T, Igarashi J, Shimizu T
Biochemistry43(44)14189-98(2004 Nov)

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results present a systematic molecular modeling study of the binding properties of murine and human p22HBP protein (heme-binding protein) with four tetrapyrrole ring systems belonging to the heme biosynthetic pathway.
Title: Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins.

mouse neutrophils, which like macrophages and dendritic cells express Fpr2, responded to human and mouse F2L in both calcium flux and chemotaxis assays
Title: F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor.

analysis of murine P22HBP structure
Title: The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.

The heme-binding properties and coordination structure of mouse liver p22HBP are distinct from those of SOUL protein, despite high sequence homology.
Title: SOUL in mouse eyes is a new hexameric heme-binding protein with characteristic optical absorption, resonance Raman spectral, and heme-binding properties.

Characterization as a tetrapyrrole-binding protein
Title: Characterization of a human and mouse tetrapyrrole-binding protein.

The following Hebp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hebp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu67933	XM_011241224.2 Latest version!	Mus musculus heme binding protein 1 (Hebp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu83491	NM_013546.3 Latest version!	Mus musculus heme binding protein 1 (Hebp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hebp1 ( XM_011241224.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239526.1 Mus musculus heme binding protein 1 (Hebp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu67933
Clone ID Related Accession (Same CDS sequence)	XM_011241224.2
Accession Version	XM_011241224.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	heme-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241224.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAGGA CTCATCTGAT GGAGTACAGG GGCAGCAGAA ATATCTTCCA GGCAGAGGAA 
GCAACAGCAA TGAGTGGGAG CGTCGTGGGC ATCAAAGGAA ACAACAGGAA CCTGACATGG 
CTCCCACCTG TAATCCCGGC TCCCATGAGG CTGAGGCAGG AGGATCACTG TGAGTTTGAG 
GAAGATGTCT CCTATGAGGA AAGAGCCTGT GAAGGGGGCA AGTTTGCTAC TGTGGAAGTG 
ACAGACAAGC CAGTGGATGA GGCTCTCCGG GAAGCGATGC CCAAGATCAT GAAGTATGTG 
GGTGGCACCA ATGACAAAGG AGTCGGCATG GGTATGACAG TCCCTGTCTC TTTTGCCGTG 
TTTCCCAATG AAGATGGCTC CCTACAGAAG AAACTGAAAG TCTGGTTCCG GATTCCGAAC 
CAATTTCAAG GCAGCCCACC GGCCCCCAGT GATGAGAGTG TGAAGATCGA GGAACGGGAG 
GGCATCACTG TCTATTCCAC GCAATTTGGA GGCTATGCCA AGGAAGCAGA CTATGTTGCT 
CATGCCACCC AGCTACGGAC CACACTGGAG GGCACACCAG CGACCTACCA GGGTGATGTC 
TATTACTGTG CCGGATATGA CCCTCCCATG AAGCCCTATG GACGCCGTAA CGAGGTCTGG 
CTTGTGAAGG CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239526.1
CDS	186..860
Translation	MSRTHLMEYRGSRNIFQAEEATAMSGSVVGIKGNNRNLTWLPPVIPAPMRLRQEDHCEFEEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPVSFAVFPNEDGSLQKKLKVWFRIPNQFQGSPPAPSDESVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVKA

Target ORF information:

RefSeq Version	XM_011241224.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus heme binding protein 1 (Hebp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241224.2

ORF Insert Sequence:

ATGAGTAGGA CTCATCTGAT GGAGTACAGG GGCAGCAGAA ATATCTTCCA GGCAGAGGAA 
GCAACAGCAA TGAGTGGGAG CGTCGTGGGC ATCAAAGGAA ACAACAGGAA CCTGACATGG 
CTCCCACCTG TAATCCCGGC TCCCATGAGG CTGAGGCAGG AGGATCACTG TGAGTTTGAG 
GAAGATGTCT CCTATGAGGA AAGAGCCTGT GAAGGGGGCA AGTTTGCTAC TGTGGAAGTG 
ACAGACAAGC CAGTGGATGA GGCTCTCCGG GAAGCGATGC CCAAGATCAT GAAGTATGTG 
GGTGGCACCA ATGACAAAGG AGTCGGCATG GGTATGACAG TCCCTGTCTC TTTTGCCGTG 
TTTCCCAATG AAGATGGCTC CCTACAGAAG AAACTGAAAG TCTGGTTCCG GATTCCGAAC 
CAATTTCAAG GCAGCCCACC GGCCCCCAGT GATGAGAGTG TGAAGATCGA GGAACGGGAG 
GGCATCACTG TCTATTCCAC GCAATTTGGA GGCTATGCCA AGGAAGCAGA CTATGTTGCT 
CATGCCACCC AGCTACGGAC CACACTGGAG GGCACACCAG CGACCTACCA GGGTGATGTC 
TATTACTGTG CCGGATATGA CCCTCCCATG AAGCCCTATG GACGCCGTAA CGAGGTCTGG 
CTTGTGAAGG CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hebp1 ( NM_013546.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038574.3 Mus musculus heme binding protein 1 (Hebp1), mRNA.

Price & Availability↑

CloneID	OMu83491
Clone ID Related Accession (Same CDS sequence)	NM_013546.3
Accession Version	NM_013546.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 573bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	heme-binding protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY242687.1, AC131718.5, AK008919.1 and AI527209.1. On Nov 17, 2015 this sequence version replaced NM_013546.2. ##Evidence-Data-START## Transcript exon combination :: AF117613.1, BI557612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGGGCA TGATCAGGAA CTCACTGTTC GGGAGCGTGG AAACGTGGCC TTGGCAGGTT 
CTAAGCACCG GGGGCAAGGA AGATGTCTCC TATGAGGAAA GAGCCTGTGA AGGGGGCAAG 
TTTGCTACTG TGGAAGTGAC AGACAAGCCA GTGGATGAGG CTCTCCGGGA AGCGATGCCC 
AAGATCATGA AGTATGTGGG TGGCACCAAT GACAAAGGAG TCGGCATGGG TATGACAGTC 
CCTGTCTCTT TTGCCGTGTT TCCCAATGAA GATGGCTCCC TACAGAAGAA ACTGAAAGTC 
TGGTTCCGGA TTCCGAACCA ATTTCAAGGC AGCCCACCGG CCCCCAGTGA TGAGAGTGTG 
AAGATCGAGG AACGGGAGGG CATCACTGTC TATTCCACGC AATTTGGAGG CTATGCCAAG 
GAAGCAGACT ATGTTGCTCA TGCCACCCAG CTACGGACCA CACTGGAGGG CACACCAGCG 
ACCTACCAGG GTGATGTCTA TTACTGTGCC GGATATGACC CTCCCATGAA GCCCTATGGA 
CGCCGTAACG AGGTCTGGCT TGTGAAGGCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038574.3
CDS	119..691
Translation	MLGMIRNSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPVSFAVFPNEDGSLQKKLKVWFRIPNQFQGSPPAPSDESVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVKA

Target ORF information:

RefSeq Version	NM_013546.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus heme binding protein 1 (Hebp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013546.3

ORF Insert Sequence:

ATGTTGGGCA TGATCAGGAA CTCACTGTTC GGGAGCGTGG AAACGTGGCC TTGGCAGGTT 
CTAAGCACCG GGGGCAAGGA AGATGTCTCC TATGAGGAAA GAGCCTGTGA AGGGGGCAAG 
TTTGCTACTG TGGAAGTGAC AGACAAGCCA GTGGATGAGG CTCTCCGGGA AGCGATGCCC 
AAGATCATGA AGTATGTGGG TGGCACCAAT GACAAAGGAG TCGGCATGGG TATGACAGTC 
CCTGTCTCTT TTGCCGTGTT TCCCAATGAA GATGGCTCCC TACAGAAGAA ACTGAAAGTC 
TGGTTCCGGA TTCCGAACCA ATTTCAAGGC AGCCCACCGG CCCCCAGTGA TGAGAGTGTG 
AAGATCGAGG AACGGGAGGG CATCACTGTC TATTCCACGC AATTTGGAGG CTATGCCAAG 
GAAGCAGACT ATGTTGCTCA TGCCACCCAG CTACGGACCA CACTGGAGGG CACACCAGCG 
ACCTACCAGG GTGATGTCTA TTACTGTGCC GGATATGACC CTCCCATGAA GCCCTATGGA 
CGCCGTAACG AGGTCTGGCT TGTGAAGGCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins.
Journal of molecular graphics & modelling29(3)396-405(2010 Nov)
Micaelo NM,Macedo AL,Goodfellow BJ,F?lix V

F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor.
Journal of immunology (Baltimore, Md. : 1950)178(3)1450-6(2007 Feb)
Gao JL,Guillabert A,Hu J,Le Y,Urizar E,Seligman E,Fang KJ,Yuan X,Imbault V,Communi D,Wang JM,Parmentier M,Murphy PM,Migeotte I

The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.
The Journal of biological chemistry281(42)31553-61(2006 Oct)
Dias JS,Macedo AL,Ferreira GC,Peterson FC,Volkman BF,Goodfellow BJ

SOUL in mouse eyes is a new hexameric heme-binding protein with characteristic optical absorption, resonance Raman spectral, and heme-binding properties.
Biochemistry43(44)14189-98(2004 Nov)
Sato E,Sagami I,Uchida T,Sato A,Kitagawa T,Igarashi J,Shimizu T

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Cell115(5)629-40(2003 Nov)
Mootha VK,Bunkenborg J,Olsen JV,Hjerrild M,Wisniewski JR,Stahl E,Bolouri MS,Ray HN,Sihag S,Kamal M,Patterson N,Lander ES,Mann M

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Hebp1 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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