H2-Ob cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	H2-Ob
Entrez Gene ID	15002
Full Name	histocompatibility 2, O region beta locus
Synonyms	A-beta-2,A-beta2,H-2Ab,H-2I,H-2Ob,H2-Ab,H2-Ab2,H2-IAb2,Ob
General protein information	Preferred Names histocompatibility 2, O region beta locus Names histocompatibility 2, O region beta locus H2-IA-beta-2 antigen MHC class II antigen O region beta locus isoform-003
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 17.98 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_017317261.1	XP_017172750.1	histocompatibility 2, O region beta locus isoform X2
XM_006523686.2	XP_006523749.1	histocompatibility 2, O region beta locus isoform X1
NM_010389.3	NP_034519.2	histocompatibility 2, O region beta locus precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	HLA-DOB	NP_002111.1
Rattus norvegicus (Norway rat)	RT1-DOb	NP_001008846.1
Pan troglodytes (chimpanzee)	PATR-DOB	NP_001123943.1
	MAMU-DOB	XP_001115393.1
Canis lupus familiaris (dog)	DLA-DOB	NP_001041592.1
Bos taurus (cattle)	BOLA-DOB	NP_001013618.1
Mus musculus (house mouse)	H2-Ob	NP_034519.2

Gene Ontology
Bibliography

Related articles in PubMed

Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob.
Denzin LK, Khan AA, Virdis F, Wilks J, Kane M, Beilinson HA, Dikiy S, Case LK, Roopenian D, Witkowski M, Chervonsky AV, Golovkina TV
Immunity47(2)310-322.e7(2017 Aug)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.
Logunova N, Korotetskaya M, Polshakov V, Apt A
PLoS genetics11(11)e1005672(2015 Nov)

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)

Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry.
Kane M, Case LK, Wang C, Yurkovetskiy L, Dikiy S, Golovkina TV
Immunity35(1)135-45(2011 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results report positional cloning of the gene responsible for production of retrovirus-neutralizing antibodies in mice of the I/LnJ strain; it encodes the beta subunit of the non-classical major histocompatibility complex class II (MHC-II)-like molecule H2-O, a negative regulator of antigen presentation
Title: Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob.

H2-O predominantly inhibits antigen presentation in early endosomal compartments. Thus, H2-O appears to skew peptide loading to late endosomal/lysosomal compartments. This may favor presentation of antigens taken up by the B cell receptor.
Title: Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes.

The following H2-Ob gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H2-Ob cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06087	NM_010389.3 Latest version!	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu53159	XM_006523686.2 Latest version!	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu79469	XM_017317261.1 Latest version!	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H2-Ob ( NM_010389.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034519.2 Mus musculus histocompatibility 2, O region beta locus (H2-Ob), mRNA.

Price & Availability↑

CloneID	OMu06087
Clone ID Related Accession (Same CDS sequence)	NM_010389.3
Accession Version	NM_010389.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	histocompatibility 2, O region beta locus precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY205160.1, AK155650.1, AK053233.1 and AF027865.1. On Jan 28, 2006 this sequence version replaced NM_010389.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK155650.1, SRR1660819.137653.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCGCTG GGAGGGCCCC CTGGGTGGTG GCTCTGTTGG TGAACCTCAT GAGGCTGGAT 
TCCTTCATGA TTGAAGGCAG AGACTCCCCA GAGAATTTTG TGATTCAGGC AAAGGCGGAC 
TGTTACTTCA CCAATGGTAC AGAAAAGGTT CACTTGCTGG TCAGGTTCAT CTTCAACCTG 
GAGGAGTATT TACACTTCGA CAGTGACCTG GGGATGTTTG TGGCTCTGAC GGAGCTGGGG 
GAACCTGATG CTGACCAGTG GAACAAACGC CTGGATCTCC TGGAGACGAG CAGAGCTGCT 
GTGAACATGG TCTGCAGGCA GAAGTACAAG CTGGGGGCCC CCTTCACTGT GGAGAGAAAT 
GTGCCTCCAG AGGTGACAGT GTATCCAGAG AGGACCCCGT TGCTGCAGCA GCACAACCTG 
CTGCTCTGCT CTGTGACAGG CTTCTACCCC GGGGACATAA GTGTCAAGTG GTTCCGGAAT 
GGACAGGAGG AGAGGTCTGG GGTCATGTCC ACTGGCCTTG TTAGGAATGG AGACTGGACC 
TTCCAGACAA CAGTAATGCT GGAAATGATC CCAGAGCTTG GTGACATCTA CAGCTGCCTC 
GTGGAGCACC CCGGCCTCCT GAGACCTGTT TCTGTGGCAT GGATGGCTCA GTCTGAATAT 
TCCTGGAAAA AGATACTGAG TGGAGCTGCA GTGTTCCTGC TTGGGCTGAT TGTCTTCCTG 
GTGGGGGTTG TTATCCATCT CAAGGCTCAG AAAGCATCTG TGGAGACTCA GCCTGGCAAT 
GAGGCCTCAA GAGAGAGTCT CCATTCTCAA CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034519.2
CDS	68..883
Translation	MGAGRAPWVVALLVNLMRLDSFMIEGRDSPENFVIQAKADCYFTNGTEKVHLLVRFIFNLEEYLHFDSDLGMFVALTELGEPDADQWNKRLDLLETSRAAVNMVCRQKYKLGAPFTVERNVPPEVTVYPERTPLLQQHNLLLCSVTGFYPGDISVKWFRNGQEERSGVMSTGLVRNGDWTFQTTVMLEMIPELGDIYSCLVEHPGLLRPVSVAWMAQSEYSWKKILSGAAVFLLGLIVFLVGVVIHLKAQKASVETQPGNEASRESLHSQP

Target ORF information:

RefSeq Version	NM_010389.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010389.3

ORF Insert Sequence:

ATGGGCGCTG GGAGGGCCCC CTGGGTGGTG GCTCTGTTGG TGAACCTCAT GAGGCTGGAT 
TCCTTCATGA TTGAAGGCAG AGACTCCCCA GAGAATTTTG TGATTCAGGC AAAGGCGGAC 
TGTTACTTCA CCAATGGTAC AGAAAAGGTT CACTTGCTGG TCAGGTTCAT CTTCAACCTG 
GAGGAGTATT TACACTTCGA CAGTGACCTG GGGATGTTTG TGGCTCTGAC GGAGCTGGGG 
GAACCTGATG CTGACCAGTG GAACAAACGC CTGGATCTCC TGGAGACGAG CAGAGCTGCT 
GTGAACATGG TCTGCAGGCA GAAGTACAAG CTGGGGGCCC CCTTCACTGT GGAGAGAAAT 
GTGCCTCCAG AGGTGACAGT GTATCCAGAG AGGACCCCGT TGCTGCAGCA GCACAACCTG 
CTGCTCTGCT CTGTGACAGG CTTCTACCCC GGGGACATAA GTGTCAAGTG GTTCCGGAAT 
GGACAGGAGG AGAGGTCTGG GGTCATGTCC ACTGGCCTTG TTAGGAATGG AGACTGGACC 
TTCCAGACAA CAGTAATGCT GGAAATGATC CCAGAGCTTG GTGACATCTA CAGCTGCCTC 
GTGGAGCACC CCGGCCTCCT GAGACCTGTT TCTGTGGCAT GGATGGCTCA GTCTGAATAT 
TCCTGGAAAA AGATACTGAG TGGAGCTGCA GTGTTCCTGC TTGGGCTGAT TGTCTTCCTG 
GTGGGGGTTG TTATCCATCT CAAGGCTCAG AAAGCATCTG TGGAGACTCA GCCTGGCAAT 
GAGGCCTCAA GAGAGAGTCT CCATTCTCAA CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

H2-Ob ( XM_006523686.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006523749.1 Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53159
Clone ID Related Accession (Same CDS sequence)	XM_006523686.2
Accession Version	XM_006523686.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	histocompatibility 2, O region beta locus isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006523686.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTGTGG CTCTGACGGA GCTGGGGGAA CCTGATGCTG ACCAGTGGAA CAAACGCCTG 
GATCTCCTGG AGACGAGCAG AGCTGCTGTG AACATGGTCT GCAGGCAGAA GTACAAGCTG 
GGGGCCCCCT TCACTGTGGA GAGAAATGTG CCTCCAGAGG TGACAGTGTA TCCAGAGAGG 
ACCCCGTTGC TGCAGCAGCA CAACCTGCTG CTCTGCTCTG TGACAGGCTT CTACCCCGGG 
GACATAAGTG TCAAGTGGTT CCGGAATGGA CAGGAGGAGA GGTCTGGGGT CATGTCCACT 
GGCCTTGTTA GGAATGGAGA CTGGACCTTC CAGACAACAG TAATGCTGGA AATGATCCCA 
GAGCTTGGTG ACATCTACAG CTGCCTCGTG GAGCACCCCG GCCTCCTGAG ACCTGTTTCT 
GTGGCATGGA TGGCTCAGTC TGAATATTCC TGGAAAAAGA TACTGAGTGG AGCTGCAGTG 
TTCCTGCTTG GGCTGATTGT CTTCCTGGTG GGGGTTGTTA TCCATCTCAA GGCTCAGAAA 
GCATCTGTGG AGACTCAGCC TGGCAATGAG GCCTCAAGAG AGAGTCTCCA TTCTCAACCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006523749.1
CDS	326..928
Translation	MFVALTELGEPDADQWNKRLDLLETSRAAVNMVCRQKYKLGAPFTVERNVPPEVTVYPERTPLLQQHNLLLCSVTGFYPGDISVKWFRNGQEERSGVMSTGLVRNGDWTFQTTVMLEMIPELGDIYSCLVEHPGLLRPVSVAWMAQSEYSWKKILSGAAVFLLGLIVFLVGVVIHLKAQKASVETQPGNEASRESLHSQP

Target ORF information:

RefSeq Version	XM_006523686.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523686.2

ORF Insert Sequence:

ATGTTTGTGG CTCTGACGGA GCTGGGGGAA CCTGATGCTG ACCAGTGGAA CAAACGCCTG 
GATCTCCTGG AGACGAGCAG AGCTGCTGTG AACATGGTCT GCAGGCAGAA GTACAAGCTG 
GGGGCCCCCT TCACTGTGGA GAGAAATGTG CCTCCAGAGG TGACAGTGTA TCCAGAGAGG 
ACCCCGTTGC TGCAGCAGCA CAACCTGCTG CTCTGCTCTG TGACAGGCTT CTACCCCGGG 
GACATAAGTG TCAAGTGGTT CCGGAATGGA CAGGAGGAGA GGTCTGGGGT CATGTCCACT 
GGCCTTGTTA GGAATGGAGA CTGGACCTTC CAGACAACAG TAATGCTGGA AATGATCCCA 
GAGCTTGGTG ACATCTACAG CTGCCTCGTG GAGCACCCCG GCCTCCTGAG ACCTGTTTCT 
GTGGCATGGA TGGCTCAGTC TGAATATTCC TGGAAAAAGA TACTGAGTGG AGCTGCAGTG 
TTCCTGCTTG GGCTGATTGT CTTCCTGGTG GGGGTTGTTA TCCATCTCAA GGCTCAGAAA 
GCATCTGTGG AGACTCAGCC TGGCAATGAG GCCTCAAGAG AGAGTCTCCA TTCTCAACCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

H2-Ob ( XM_017317261.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017172750.1 Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu79469
Clone ID Related Accession (Same CDS sequence)	XM_017317261.1
Accession Version	XM_017317261.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	histocompatibility 2, O region beta locus isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGCTG GGAGGGCCCC CTGGGTGGTG GCTCTGTTGG TGAACCTCAT GAGGCTGGAT 
TCCTTCATGA TTGAAGGCAG AGACTCCCCA GAGAATTTTG TGATTCAGGC AAAGGCGGAC 
TGTTACTTCA CCAATGGTAC AGAAAAGGTT CACTTGCTGG TCAGGTTCAT CTTCAACCTG 
GAGGAGTATT TACACTTCGA CAGTGACCTG GGGATGTTTG TGGCTCTGAC GGAGCTGGGG 
GAACCTGATG CTGACCAGTG GAACAAACGC CTGGATCTCC TGGAGACGAG CAGAGCTGCT 
GTGAACATGG TCTGCAGGCA GAAGTACAAG CTGGGGGCCC CCTTCACTGT GGAGAGAAAT 
GTGCCTCCAG AGGTGACAGT GTATCCAGAG AGGACCCCGT TGCTGCAGCA GCACAACCTG 
CTGCTCTGCT CTGTGACAGG CTTCTACCCC GGGGACATAA GTGTCAAGTG GTTCCGGAAT 
GGACAGGAGG AGAGGTCTGG GGTCATGTCC ACTGGCCTTG TTAGGAATGG AGACTGGACC 
TTCCAGACAA CAGTAATGCT GGAAATGATC CCAGAGCTTG GTGACATCTA CAGCTGCCTC 
GTGGAGCACC CCGGCCTCCT GAGACCTGTT TCTGTGGCAT GGATGGCTCA GTCTGAATAT 
TCCTGGAAAA AGATACTGAG TGGAGCTGCA GTGTTCCTGC TTGGGCTGAT TGTCTTCCTG 
GTGGGGGTTG TTATCCATCT CAAGGCTCAG AAAGCATCTG TGGAGACTCA GCCTGGCAAT 
GAGAGTAGGT CCCGGATGAT GGAGCGGCTA ACCAAGTTCA AGGCTGGACC GGGACATGTC 
ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017172750.1
CDS	78..923
Translation	MGAGRAPWVVALLVNLMRLDSFMIEGRDSPENFVIQAKADCYFTNGTEKVHLLVRFIFNLEEYLHFDSDLGMFVALTELGEPDADQWNKRLDLLETSRAAVNMVCRQKYKLGAPFTVERNVPPEVTVYPERTPLLQQHNLLLCSVTGFYPGDISVKWFRNGQEERSGVMSTGLVRNGDWTFQTTVMLEMIPELGDIYSCLVEHPGLLRPVSVAWMAQSEYSWKKILSGAAVFLLGLIVFLVGVVIHLKAQKASVETQPGNESRSRMMERLTKFKAGPGHVT

Target ORF information:

RefSeq Version	XM_017317261.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, O region beta locus (H2-Ob), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017317261.1

ORF Insert Sequence:

ATGGGCGCTG GGAGGGCCCC CTGGGTGGTG GCTCTGTTGG TGAACCTCAT GAGGCTGGAT 
TCCTTCATGA TTGAAGGCAG AGACTCCCCA GAGAATTTTG TGATTCAGGC AAAGGCGGAC 
TGTTACTTCA CCAATGGTAC AGAAAAGGTT CACTTGCTGG TCAGGTTCAT CTTCAACCTG 
GAGGAGTATT TACACTTCGA CAGTGACCTG GGGATGTTTG TGGCTCTGAC GGAGCTGGGG 
GAACCTGATG CTGACCAGTG GAACAAACGC CTGGATCTCC TGGAGACGAG CAGAGCTGCT 
GTGAACATGG TCTGCAGGCA GAAGTACAAG CTGGGGGCCC CCTTCACTGT GGAGAGAAAT 
GTGCCTCCAG AGGTGACAGT GTATCCAGAG AGGACCCCGT TGCTGCAGCA GCACAACCTG 
CTGCTCTGCT CTGTGACAGG CTTCTACCCC GGGGACATAA GTGTCAAGTG GTTCCGGAAT 
GGACAGGAGG AGAGGTCTGG GGTCATGTCC ACTGGCCTTG TTAGGAATGG AGACTGGACC 
TTCCAGACAA CAGTAATGCT GGAAATGATC CCAGAGCTTG GTGACATCTA CAGCTGCCTC 
GTGGAGCACC CCGGCCTCCT GAGACCTGTT TCTGTGGCAT GGATGGCTCA GTCTGAATAT 
TCCTGGAAAA AGATACTGAG TGGAGCTGCA GTGTTCCTGC TTGGGCTGAT TGTCTTCCTG 
GTGGGGGTTG TTATCCATCT CAAGGCTCAG AAAGCATCTG TGGAGACTCA GCCTGGCAAT 
GAGAGTAGGT CCCGGATGAT GGAGCGGCTA ACCAAGTTCA AGGCTGGACC GGGACATGTC 
ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob.
Immunity47(2)310-322.e7(2017 Aug)
Denzin LK,Khan AA,Virdis F,Wilks J,Kane M,Beilinson HA,Dikiy S,Case LK,Roopenian D,Witkowski M,Chervonsky AV,Golovkina TV

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.
PLoS genetics11(11)e1005672(2015 Nov)
Logunova N,Korotetskaya M,Polshakov V,Apt A

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Immunity43(4)690-702(2015 Oct)
Ray JP,Staron MM,Shyer JA,Ho PC,Marshall HD,Gray SM,Laidlaw BJ,Araki K,Ahmed R,Kaech SM,Craft J

Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry.
Immunity35(1)135-45(2011 Jul)
Kane M,Case LK,Wang C,Yurkovetskiy L,Dikiy S,Golovkina TV

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H2-Ob cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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