Pfdn6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pfdn6
Entrez Gene ID	14976
Full Name	prefoldin subunit 6
Synonyms	H-2Ke2,H2-Ke2,Ke-2
General protein information	Preferred Names prefoldin subunit 6 Names prefoldin subunit 6 H2-K region expressed gene 2 protein Ke2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 17.98 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001185182.1	NP_001172111.1	prefoldin subunit 6
NM_010385.2	NP_034515.1	prefoldin subunit 6

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG7770	NP_001262079.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012235	XP_320305.3
Homo sapiens (human)	PFDN6	NP_001252524.1
Bos taurus (cattle)	PFDN6	NP_001068889.1
Mus musculus (house mouse)	H2-Ke2	NP_034515.1
Oryza sativa (rice)	Os02g0246300	NP_001046425.2
Pan troglodytes (chimpanzee)	PFDN6	XP_527361.1
	PFDN6	XP_001116232.1
Canis lupus familiaris (dog)	PFDN6	NP_001041554.1
Danio rerio (zebrafish)	pfdn6	NP_956807.1
Arabidopsis thaliana (thale cress)	PFD6	NP_174292.2
Xenopus tropicalis (tropical clawed frog)	pfdn6	NP_001015908.1
Rattus norvegicus (Norway rat)	Pfdn6	NP_997671.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.
Logunova N, Korotetskaya M, Polshakov V, Apt A
PLoS genetics11(11)e1005672(2015 Nov)

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Dai N, Zhao L, Wrighting D, Kr?mer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
Cell metabolism21(4)609-21(2015 Apr)

Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD
Genome biology9(6)R99(2008)

Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.
Abe K, Yuzuriha M, Sugimoto M, Ko MS, Brathwaite M, Waeltz P, Nagaraja R
Mammalian genome : official journal of the International Mammalian Genome Society15(4)265-76(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pfdn6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pfdn6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23378	NM_001185182.1 Latest version!	Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu23378	NM_010385.2 Latest version!	Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pfdn6 ( NM_001185182.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001172111.1 Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23378
Clone ID Related Accession (Same CDS sequence)	NM_001185182.1 , NM_010385.2
Accession Version	NM_001185182.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	prefoldin subunit 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR974462.5, AA023721.1 and AV446044.1. Transcript Variant: This variant (2) lacks an internal segment in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AA023721.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGAAC TGATCCAAAA GAAGCTGCAG GGAGAGGTAG AGAAATATCA ACAGCTGCAG 
AAGGACTTGA GTAAATCTAT GTCAGGGAGG CAGAAGCTCG AAGCACAGCT AACGGAAAAC 
AATATCGTGA AGGAGGAGCT GGCCCTGCTG GATGGATCCA ACGTGGTCTT TAAGCTTCTG 
GGACCCGTGC TTGTCAAACA GGAGCTGGGG GAGGCTCGGG CCACAGTAGG GAAGAGGCTA 
GACTACATCA CAGCAGAAAT CAAGCGCTAC GAATCACAGC TTCGGGACCT CGAGCGGCAG 
TCAGAGCAAC AGAGGGAAAC CCTTGCTCAA CTGCAGCAGG AGTTTCAGCG GGCCCAAGCT 
GCAAAGGCTC CTGGGAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172111.1
CDS	53..436
Translation	MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAPGKA

Target ORF information:

RefSeq Version	NM_001185182.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185182.1

ORF Insert Sequence:

ATGGCTGAAC TGATCCAAAA GAAGCTGCAG GGAGAGGTAG AGAAATATCA ACAGCTGCAG 
AAGGACTTGA GTAAATCTAT GTCAGGGAGG CAGAAGCTCG AAGCACAGCT AACGGAAAAC 
AATATCGTGA AGGAGGAGCT GGCCCTGCTG GATGGATCCA ACGTGGTCTT TAAGCTTCTG 
GGACCCGTGC TTGTCAAACA GGAGCTGGGG GAGGCTCGGG CCACAGTAGG GAAGAGGCTA 
GACTACATCA CAGCAGAAAT CAAGCGCTAC GAATCACAGC TTCGGGACCT CGAGCGGCAG 
TCAGAGCAAC AGAGGGAAAC CCTTGCTCAA CTGCAGCAGG AGTTTCAGCG GGCCCAAGCT 
GCAAAGGCTC CTGGGAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pfdn6 ( NM_010385.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034515.1 Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23378
Clone ID Related Accession (Same CDS sequence)	NM_001185182.1 , NM_010385.2
Accession Version	NM_010385.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	prefoldin subunit 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY238879.1, AK010679.1 and AV446044.1. On Apr 20, 2007 this sequence version replaced NM_010385.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.138296.1, SRR1660815.343787.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAC TGATCCAAAA GAAGCTGCAG GGAGAGGTAG AGAAATATCA ACAGCTGCAG 
AAGGACTTGA GTAAATCTAT GTCAGGGAGG CAGAAGCTCG AAGCACAGCT AACGGAAAAC 
AATATCGTGA AGGAGGAGCT GGCCCTGCTG GATGGATCCA ACGTGGTCTT TAAGCTTCTG 
GGACCCGTGC TTGTCAAACA GGAGCTGGGG GAGGCTCGGG CCACAGTAGG GAAGAGGCTA 
GACTACATCA CAGCAGAAAT CAAGCGCTAC GAATCACAGC TTCGGGACCT CGAGCGGCAG 
TCAGAGCAAC AGAGGGAAAC CCTTGCTCAA CTGCAGCAGG AGTTTCAGCG GGCCCAAGCT 
GCAAAGGCTC CTGGGAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034515.1
CDS	257..640
Translation	MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAPGKA

Target ORF information:

RefSeq Version	NM_010385.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus prefoldin subunit 6 (Pfdn6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010385.2

ORF Insert Sequence:

ATGGCTGAAC TGATCCAAAA GAAGCTGCAG GGAGAGGTAG AGAAATATCA ACAGCTGCAG 
AAGGACTTGA GTAAATCTAT GTCAGGGAGG CAGAAGCTCG AAGCACAGCT AACGGAAAAC 
AATATCGTGA AGGAGGAGCT GGCCCTGCTG GATGGATCCA ACGTGGTCTT TAAGCTTCTG 
GGACCCGTGC TTGTCAAACA GGAGCTGGGG GAGGCTCGGG CCACAGTAGG GAAGAGGCTA 
GACTACATCA CAGCAGAAAT CAAGCGCTAC GAATCACAGC TTCGGGACCT CGAGCGGCAG 
TCAGAGCAAC AGAGGGAAAC CCTTGCTCAA CTGCAGCAGG AGTTTCAGCG GGCCCAAGCT 
GCAAAGGCTC CTGGGAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.
PLoS genetics11(11)e1005672(2015 Nov)
Logunova N,Korotetskaya M,Polshakov V,Apt A

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Cell metabolism21(4)609-21(2015 Apr)
Dai N,Zhao L,Wrighting D,Kr?mer D,Majithia A,Wang Y,Cracan V,Borges-Rivera D,Mootha VK,Nahrendorf M,Thorburn DR,Minichiello L,Altshuler D,Avruch J

Identification of transcripts with enriched expression in the developing and adult pancreas.
Genome biology9(6)R99(2008)
Hoffman BG,Zavaglia B,Witzsche J,Ruiz de Algara T,Beach M,Hoodless PA,Jones SJ,Marra MA,Helgason CD

Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.
Mammalian genome : official journal of the International Mammalian Genome Society15(4)265-76(2004 Apr)
Abe K,Yuzuriha M,Sugimoto M,Ko MS,Brathwaite M,Waeltz P,Nagaraja R

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Pfdn6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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