Gsta1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gsta1
Entrez Gene ID	14857
Full Name	glutathione S-transferase, alpha 1 (Ya)
Synonyms	Gst2-1
General protein information	Preferred Names glutathione S-transferase, alpha 1 (Ya) Names glutathione S-transferase A1 GST class-alpha member 1 glutathione S-transferase Ya glutathione S-transferase Ya1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 E1\|9 43.65 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008181.3	NP_032207.3	glutathione S-transferase A1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gm10639	NP_001116132.1
Homo sapiens (human)	GSTA5	NP_714543.1
Mus musculus (house mouse)	Gm3776	NP_001230021.1
Pan troglodytes (chimpanzee)	GSTA5	XP_001153791.1
	LOC709417	XP_001108174.1
Mus musculus (house mouse)	Gsta2	NP_032208.2
Mus musculus (house mouse)	Gsta1	NP_032207.3
Rattus norvegicus (Norway rat)	Gsta5	NP_001010921.1

Gene Ontology
Bibliography

Related articles in PubMed

Glutathione S-transferase A1 - a sensitive marker of alcoholic injury on primary hepatocytes.
Chang YC, Liu FP, Ma X, Li MM, Li R, Li CW, Shi CX, He JS, Li Z, Lin YX, Zhao CW, Han Q, Zhao YL, Wang DN, Liu JL
Human & experimental toxicology36(4)386-394(2017 Apr)

Glutathione S-transferase A1 (GSTA1) release, an early indicator of acute hepatic injury in mice.
Liu F, Lin Y, Li Z, Ma X, Han Q, Liu Y, Zhou Q, Liu J, Li R, Li J, Gao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association71225-30(2014 Sep)

Expression pattern of GSTP1 and GSTA1 in the pathogenesis of asthma.
Sohn SW, Jung JW, Lee SY, Kang HR, Park HW, Min KU, Cho SH
Experimental lung research39(4-5)173-81(2013 May-Jun)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver.
McLellan LI, Kerr LA, Cronshaw AD, Hayes JD
The Biochemical journal276 ( Pt 2)461-9(1991 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury.
Title: Glutathione S-transferase A1 - a sensitive marker of alcoholic injury on primary hepatocytes.

results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT
Title: Glutathione S-transferase A1 (GSTA1) release, an early indicator of acute hepatic injury in mice.

Report increased GSTA1 in airways of asthmatic mice.
Title: Expression pattern of GSTP1 and GSTA1 in the pathogenesis of asthma.

Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs.
Title: Methyl methacrylate activates the Gsta1 promoter.

Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis.
Title: Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.

The following Gsta1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gsta1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01486	NM_008181.3 Latest version!	Mus musculus glutathione S-transferase, alpha 1 (Ya) (Gsta1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gsta1 ( NM_008181.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032207.3 Mus musculus glutathione S-transferase, alpha 1 (Ya) (Gsta1), mRNA.

Price & Availability↑

CloneID	OMu01486
Clone ID Related Accession (Same CDS sequence)	NM_008181.3
Accession Version	NM_008181.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	glutathione S-transferase A1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY080629.1, BC132572.1 and CJ228212.1. On Aug 1, 2007 this sequence version replaced NM_008181.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ947704.1, BC132572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGA AGCCCGTGCT TCACTACTTC AATGCCCGGG GCAGAATGGA GTGCATCAGG 
TGGCTCCTGG CTGCAGCAGG GGTGGAGTTT GAAGAGAAGT TTATACAGAG TCCGGAAGAT 
TTGGAAAAGC TAAAAAAAGA TGGGAATTTG ATGTTTGACC AAGTGCCCAT GGTGGAGATT 
GATGGGATGA AGCTGGCGCA GACCAGAGCC ATTCTCAACT ACATCGCCAC CAAATATGAC 
CTCTATGGGA AGGACATGAA GGAGAGAGCC CTGATTGACA TGTATTCAGA AGGTATTTTA 
GATCTGACTG AAATGATTGG GCAATTGGTA TTATGTCCCC CAGACCAAAG AGAAGCCAAG 
ACTGCCTTGG CAAAAGATAG GACCAAAAAC CGTTACTTGC CTGCCTTTGA AAAGGTGTTG 
AAGAGCCATG GACAAGACTA CCTTGTGGGC AACAGGCTGA CCAGGGTGGA CATCCACCTA 
CTGGAAGTTC TCCTCTATGT TGAAGAGTTT GATGCCAGCC TTCTGACCCC TTTCCCTCTG 
CTGAAGGCCT TCAAGAGCAG AATCAGCAGC CTCCCCAATG TGAAGAAGTT CCTACAGCCT 
GGCAGCCAGA GAAAGCCTCC CATGGATGCA AAACAAATTC AAGAAGCAAG GAAGGCTTTC 
AAGATTCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032207.3
CDS	85..756
Translation	MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKIQ

Target ORF information:

RefSeq Version	NM_008181.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus glutathione S-transferase, alpha 1 (Ya) (Gsta1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008181.3

ORF Insert Sequence:

ATGGCCGGGA AGCCCGTGCT TCACTACTTC AATGCCCGGG GCAGAATGGA GTGCATCAGG 
TGGCTCCTGG CTGCAGCAGG GGTGGAGTTT GAAGAGAAGT TTATACAGAG TCCGGAAGAT 
TTGGAAAAGC TAAAAAAAGA TGGGAATTTG ATGTTTGACC AAGTGCCCAT GGTGGAGATT 
GATGGGATGA AGCTGGCGCA GACCAGAGCC ATTCTCAACT ACATCGCCAC CAAATATGAC 
CTCTATGGGA AGGACATGAA GGAGAGAGCC CTGATTGACA TGTATTCAGA AGGTATTTTA 
GATCTGACTG AAATGATTGG GCAATTGGTA TTATGTCCCC CAGACCAAAG AGAAGCCAAG 
ACTGCCTTGG CAAAAGATAG GACCAAAAAC CGTTACTTGC CTGCCTTTGA AAAGGTGTTG 
AAGAGCCATG GACAAGACTA CCTTGTGGGC AACAGGCTGA CCAGGGTGGA CATCCACCTA 
CTGGAAGTTC TCCTCTATGT TGAAGAGTTT GATGCCAGCC TTCTGACCCC TTTCCCTCTG 
CTGAAGGCCT TCAAGAGCAG AATCAGCAGC CTCCCCAATG TGAAGAAGTT CCTACAGCCT 
GGCAGCCAGA GAAAGCCTCC CATGGATGCA AAACAAATTC AAGAAGCAAG GAAGGCTTTC 
AAGATTCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glutathione S-transferase A1 - a sensitive marker of alcoholic injury on primary hepatocytes.
Human & experimental toxicology36(4)386-394(2017 Apr)
Chang YC,Liu FP,Ma X,Li MM,Li R,Li CW,Shi CX,He JS,Li Z,Lin YX,Zhao CW,Han Q,Zhao YL,Wang DN,Liu JL

Glutathione S-transferase A1 (GSTA1) release, an early indicator of acute hepatic injury in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association71225-30(2014 Sep)
Liu F,Lin Y,Li Z,Ma X,Han Q,Liu Y,Zhou Q,Liu J,Li R,Li J,Gao L

Expression pattern of GSTP1 and GSTA1 in the pathogenesis of asthma.
Experimental lung research39(4-5)173-81(2013 May-Jun)
Sohn SW,Jung JW,Lee SY,Kang HR,Park HW,Min KU,Cho SH

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver.
The Biochemical journal276 ( Pt 2)461-9(1991 Jun)
McLellan LI,Kerr LA,Cronshaw AD,Hayes JD

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Gsta1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報