Gpr3 cDNA ORF clone, Mus musculus(house mouse)

The switch from cAMP-independent to cAMP-dependent arrest of meiotic prophase is associated with coordinated GPR3 and CDK1 expression in mouse oocytes.
Firmani LD, Uliasz TF, Mehlmann LM
Developmental biology(2017 Dec)

The Subcellular Dynamics of the Gs-Linked Receptor GPR3 Contribute to the Local Activation of PKA in Cerebellar Granular Neurons.
Miyagi T, Tanaka S, Hide I, Shirafuji T, Sakai N
PloS one11(1)e0147466(2016)

Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue.
Godlewski G, Jourdan T, Szanda G, Tam J, Cinar R, Harvey-White J, Liu J, Mukhopadhyay B, Pacher P, Ming Mo F, Osei-Hyiaman D, Kunos G
Scientific reports514953(2015 Oct)

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.
Huang Y, Skwarek-Maruszewska A, Horr? K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A
Science translational medicine7(309)309ra164(2015 Oct)

GPR3 appears to have a key role in the thermogenic response of interscapular brown adipose tissue and may represent a new therapeutic target in age-related obesity.
Title: Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue.

This study found that the expression of GPR3 in CGNs exerted prosurvival effects against apoptosis-inducing stimuli, such as potassium deprivation, hypoxia, and ROS.
Title: Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli.

Altered signalling pathways of GPR3 could contribute to the neurobiological substrate involved in developing addiction to cocaine
Title: The orphan receptor GPR3 modulates the early phases of cocaine reinforcement.

Involvement of the orphan GPR3 receptor is demonstrated for the first time in expression and development of neuropathic pain and in analgesia induced by morphine.
Title: GPR3 orphan receptor is involved in neuropathic pain after peripheral nerve injury and regulates morphine-induced antinociception.

GPR3 is a novel antiproliferative mediator of CGPs in the postnatal development of murine cerebellu
Title: The Gs-linked receptor GPR3 inhibits the proliferation of cerebellar granule cells during postnatal development.