Gdi2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gdi2
Entrez Gene ID	14569
Full Name	guanosine diphosphate (GDP) dissociation inhibitor 2
Synonyms	GDI-B,GDIB,Gdi3
General protein information	Preferred Names guanosine diphosphate (GDP) dissociation inhibitor 2 Names rab GDP dissociation inhibitor beta GDI beta GDI-2 GDI-3 RAB GDP dissociation inhibitor beta-2 guanosine diphosphate (GDP) dissociation inhibitor 3 guanosine diphosphate dissociation inhibitor 2 rab GDI beta
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_008112.4	NP_032138.3	rab GDP dissociation inhibitor beta

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GDI2	XP_507638.3
Rattus norvegicus (Norway rat)	Gdi2	NP_058972.2
Oryza sativa (rice)	Os03g0277000	NP_001049717.1
Canis lupus familiaris (dog)	GDI2	NP_001003184.1
Bos taurus (cattle)	GDI2	NP_001028934.1
Arabidopsis thaliana (thale cress)	AT5G09550	NP_196517.3
Xenopus tropicalis (tropical clawed frog)	gdi2	NP_001005676.1
Mus musculus (house mouse)	Gdi2	NP_032138.3
Danio rerio (zebrafish)	gdi2	NP_955949.1
Homo sapiens (human)	GDI2	NP_001485.2
	GDI2	XP_001105854.1
Gallus gallus (chicken)	GDI2	NP_990335.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

RabGDI? is a negative regulator of interferon-?-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.
Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M
Proceedings of the National Academy of Sciences of the United States of America112(33)E4581-90(2015 Aug)

GSK3?-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, Zhang C
PLoS biology13(4)e1002129(2015 Apr)

GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.
Chen Y, Deng Y, Zhang J, Yang L, Xie X, Xu T
The Biochemical journal422(2)229-35(2009 Aug)

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

role in regulatory mechanism of neurotransmitter release
Title: [Regulatory mechanism of neurotransmitter release by low-molecular-weight G protein, Rab3A and the regulatory proteins].

The following Gdi2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gdi2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20708	NM_008112.4 Latest version!	Mus musculus guanosine diphosphate (GDP) dissociation inhibitor 2 (Gdi2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gdi2 ( NM_008112.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032138.3 Mus musculus guanosine diphosphate (GDP) dissociation inhibitor 2 (Gdi2), mRNA.

Price & Availability↑

CloneID	OMu20708
Clone ID Related Accession (Same CDS sequence)	NM_008112.4
Accession Version	NM_008112.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Mus musculus(house mouse)
Product	rab GDP dissociation inhibitor beta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY072982.1, AK143681.1, AK083063.1 and AK163431.1. On Oct 13, 2006 this sequence version replaced NM_008112.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK078144.1, AK143633.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAATGAGG AATACGACGT GATCGTGCTG GGCACCGGCC TGACGGAATG TATCCTGTCG 
GGGATAATGT CAGTGAATGG GAAGAAGGTT CTTCATATGG ATCAGAACCC ATACTATGGA 
GGAGAAAGTG CGTCTATAAC ACCGCTGGAA GATTTATACA AAAGGTTTAA ATTACCAGGA 
CAACCGCCAG CATCAATGGG AAGAGGAAGA GACTGGAATG TTGACTTAAT TCCCAAGTTC 
CTTATGGCCA ATGGTCAGTT GGTGAAGATG CTGCTTTTCA CAGAGGTCAC TCGTTACATG 
GACTTCAAAG TGATTGAGGG AAGCTTTGTC TACAAGGGAG GGAAAATCTA CAAGGTTCCT 
TCCACTGAAG CAGAAGCCCT GGCATCTAGC TTAATGGGAC TGTTTGAGAA ACGCCGTTTC 
AGGAAGTTCC TGGTTTATGT TGCCAACTTT GATGAAAAAG ATCCTAGAAC TTTCGAGGGT 
GTTGATCCTA AGAAGACCTC CATGAGAGAT GTGTATAAGA AGTTTGATTT GGGCCAAGAT 
GTTATAGACT TTACTGGCCA TTCTCTTGCA CTGTACAGAA CAGATGACTA CTTAGATCAG 
CCGTGTTGTG AAACCATTAA TAGAATTAAA CTTTACAGCG AGTCTTTGGC AAGATACGGT 
AAAAGCCCGT ACCTGTATCC GCTTTATGGT CTTGGAGAAT TGCCGCAAGG ATTTGCAAGG 
TTAAGTGCCA TATATGGAGG TACCTACATG TTGAATAAAC CAATTGAAGA AATCATTGTG 
CAAAATGGAA AAGTGGTTGG TGTAAAATCC GAAGGAGAGA TTGCTCGCTG TAAACAGCTC 
ATCTGTGATC CCAGCTATGT AAAAGATCGG GTTGAAAAAG TGGGCCAGGT AATCAGAGTG 
ATCTGTATCC TTAGCCACCC TATCAAGAAC ACCAACGATG CCAACTCCTG CCAGATCATC 
ATTCCACAGA ACCAAGTCAA CCGCAAGTCA GATATCTATG TTTGCATGAT CTCCTTTGCA 
CATAATGTGG CAGCACAGGG CAAGTATATT GCCATTGTAA GTACAACCGT GGAGACCAAG 
GAACCAGAGA AAGAAATCAG ACCGGCTTTG GAGCTCTTGG AACCAATTGA ACAGAAATTT 
GTCAGCATCA GTGACCTCTT TGTACCTAAA GATTTGGGAA CAGATAGTCA GATCTTCATT 
TCCCGTGCCT ATGATGCTAC CACGCACTTT GAGACAACCT GTGATGACAT TAAAGATATC 
TACAAGAGGA TGACAGGATC TGAGTTTGAC TTTGAGGAAA TGAAGCGCAA GAAGAATGAC 
ATTTATGGAG AAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032138.3
CDS	225..1562
Translation	MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED

Target ORF information:

RefSeq Version	NM_008112.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanosine diphosphate (GDP) dissociation inhibitor 2 (Gdi2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008112.4

ORF Insert Sequence:

ATGAATGAGG AATACGACGT GATCGTGCTG GGCACCGGCC TGACGGAATG TATCCTGTCG 
GGGATAATGT CAGTGAATGG GAAGAAGGTT CTTCATATGG ATCAGAACCC ATACTATGGA 
GGAGAAAGTG CGTCTATAAC ACCGCTGGAA GATTTATACA AAAGGTTTAA ATTACCAGGA 
CAACCGCCAG CATCAATGGG AAGAGGAAGA GACTGGAATG TTGACTTAAT TCCCAAGTTC 
CTTATGGCCA ATGGTCAGTT GGTGAAGATG CTGCTTTTCA CAGAGGTCAC TCGTTACATG 
GACTTCAAAG TGATTGAGGG AAGCTTTGTC TACAAGGGAG GGAAAATCTA CAAGGTTCCT 
TCCACTGAAG CAGAAGCCCT GGCATCTAGC TTAATGGGAC TGTTTGAGAA ACGCCGTTTC 
AGGAAGTTCC TGGTTTATGT TGCCAACTTT GATGAAAAAG ATCCTAGAAC TTTCGAGGGT 
GTTGATCCTA AGAAGACCTC CATGAGAGAT GTGTATAAGA AGTTTGATTT GGGCCAAGAT 
GTTATAGACT TTACTGGCCA TTCTCTTGCA CTGTACAGAA CAGATGACTA CTTAGATCAG 
CCGTGTTGTG AAACCATTAA TAGAATTAAA CTTTACAGCG AGTCTTTGGC AAGATACGGT 
AAAAGCCCGT ACCTGTATCC GCTTTATGGT CTTGGAGAAT TGCCGCAAGG ATTTGCAAGG 
TTAAGTGCCA TATATGGAGG TACCTACATG TTGAATAAAC CAATTGAAGA AATCATTGTG 
CAAAATGGAA AAGTGGTTGG TGTAAAATCC GAAGGAGAGA TTGCTCGCTG TAAACAGCTC 
ATCTGTGATC CCAGCTATGT AAAAGATCGG GTTGAAAAAG TGGGCCAGGT AATCAGAGTG 
ATCTGTATCC TTAGCCACCC TATCAAGAAC ACCAACGATG CCAACTCCTG CCAGATCATC 
ATTCCACAGA ACCAAGTCAA CCGCAAGTCA GATATCTATG TTTGCATGAT CTCCTTTGCA 
CATAATGTGG CAGCACAGGG CAAGTATATT GCCATTGTAA GTACAACCGT GGAGACCAAG 
GAACCAGAGA AAGAAATCAG ACCGGCTTTG GAGCTCTTGG AACCAATTGA ACAGAAATTT 
GTCAGCATCA GTGACCTCTT TGTACCTAAA GATTTGGGAA CAGATAGTCA GATCTTCATT 
TCCCGTGCCT ATGATGCTAC CACGCACTTT GAGACAACCT GTGATGACAT TAAAGATATC 
TACAAGAGGA TGACAGGATC TGAGTTTGAC TTTGAGGAAA TGAAGCGCAA GAAGAATGAC 
ATTTATGGAG AAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

RabGDI? is a negative regulator of interferon-?-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.
Proceedings of the National Academy of Sciences of the United States of America112(33)E4581-90(2015 Aug)
Ohshima J,Sasai M,Liu J,Yamashita K,Ma JS,Lee Y,Bando H,Howard JC,Ebisu S,Hayashi M,Takeda K,Standley DM,Frickel EM,Yamamoto M

GSK3?-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
PLoS biology13(4)e1002129(2015 Apr)
Zhang B,Zhang T,Wang G,Wang G,Chi W,Jiang Q,Zhang C

GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.
The Biochemical journal422(2)229-35(2009 Aug)
Chen Y,Deng Y,Zhang J,Yang L,Xie X,Xu T

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

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Gdi2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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