G6pc2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	G6pc2
Entrez Gene ID	14378
Full Name	glucose-6-phosphatase, catalytic, 2
Synonyms	G6pc-rs,IGRP
General protein information	Preferred Names glucose-6-phosphatase, catalytic, 2 Names glucose-6-phosphatase 2 G-6-Pase 2 glucose-6-phosphatase, catalytic, related sequence islet-specific glucose-6-phosphatase catalytic subunit-related protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C2\|2 39.66 cM
Summary	This gene encodes an enzyme that belongs to the glucose-6-phosphatase catalytic subunit family. Members of this family catalyze the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, to release glucose into the bloodstream. The family member encoded by this gene is found specifically in pancreatic islets but has not been shown to have phosphotransferase or phosphatase activity exhibited by a similar liver enzyme. The non-obese diabetic (NOD) mouse is a model for human type 1 diabetes, an autoimmune disease in which T lymphocytes attack and destroy insulin-producing pancreatic beta cells. In NOD mice, the protein encoded by this gene is a major target of cell-mediated autoimmunity. Variations in the human and mouse genes are associated with lower fasting plasma glucose levels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001289857.1	NP_001276786.1	glucose-6-phosphatase 2 isoform 3
NM_021331.4	NP_067306.1	glucose-6-phosphatase 2 isoform 1
NM_001289856.1	NP_001276785.1	glucose-6-phosphatase 2 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	G6PC2	NP_066999.1
Pan troglodytes (chimpanzee)	G6PC2	XP_001155854.1
Gallus gallus (chicken)	G6PC2	XP_003641696.1
Canis lupus familiaris (dog)	G6PC2	XP_545511.3
Bos taurus (cattle)	G6PC2	NP_001178975.1
Rattus norvegicus (Norway rat)	LOC681817	XP_003749532.1
Mus musculus (house mouse)	G6pc2	NP_067306.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of
Boortz KA, Syring KE, Pound LD, Mo H, Bastarache L, Oeser JK, McGuinness OP, Denny JC, O'Brien RM
Journal of molecular endocrinology58(3)127-139(2017 Apr)

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.
Boortz KA, Syring KE, Lee RA, Dai C, Oeser JK, McGuinness OP, Wang JC, O'Brien RM
Endocrinology157(11)4133-4145(2016 Nov)

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.
Boortz KA, Syring KE, Dai C, Pound LD, Oeser JK, Jacobson DA, Wang JC, McGuinness OP, Powers AC, O'Brien RM
Endocrinology157(8)3002-8(2016 Aug)

?-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.
Abdellatif AM, Oishi H, Itagaki T, Jung Y, Shawki HH, Okita Y, Hasegawa Y, Suzuki H, El-Morsy SE, El-Sayed MA, Shoaib MB, Sugiyama F, Takahashi S
PloS one11(2)e0150010(2016)

The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.
Frigeri C, Martin CC, Svitek CA, Oeser JK, Hutton JC, Gannon M, O'Brien RM
Diabetes53(7)1754-64(2004 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These observations suggest that the action of G6PC2 on FBG is largely independent of the influences of environment, modifier genes or epigenetic events, whereas the action of G6PC2 on body weight and cholesterol are influenced by unknown variables.
Title: Effects of

The observations demonstrate that G6pc2 modulates the complex effects of Dex on both FBG and glucose tolerance.
Title: G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.

G6PC2 may have evolved to modulate FBG in response to stress.
Title: G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

Our data clearly indicate that IGRP206-214-specific in vivo CTLs in NOD mice predict diabetes.
Title: Functional cytotoxic T lymphocytes against IGRP206-214 predict diabetes in the non-obese diabetic mouse.

Data indicate glucose-6-phosphatase catalytic subunit-related protein (IGRP) as diabetogenic antigen in RIP-CD80GP transgenic mice.
Title: IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse.

The following G6pc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the G6pc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14240	NM_021331.4 Latest version!	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu23257	NM_001289857.1 Latest version!	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu23288	NM_001289856.1 Latest version!	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

G6pc2 ( NM_021331.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067306.1 Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14240
Clone ID Related Accession (Same CDS sequence)	NM_021331.4
Accession Version	NM_021331.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	glucose-6-phosphatase 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK148450.1, AK148465.1 and BP758187.1. On Feb 4, 2014 this sequence version replaced NM_021331.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148465.1, Z47787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATTTCC TTCATAGGAG TGGAGTGCTT ATTATTCATC ATCTGCAGGA GGACTACCGG 
ACTTACTATG GTTTTCTAAA TTTTATGTCC AATGTTGGAG ACCCCCGAAA TATCTTTTCT 
ATTTACTTCC CACTTTGGTT TCAGTTGAAT CAGAATGTTG GAACCAAGAT GATCTGGGTA 
GCGGTCATAG GGGACTGGTT CAATCTCATA TTTAAATGGA TATTGTTTGG CCATCGTCCT 
TACTGGTGGA TACAAGAAAC TGAGATTTAT CCAAATCATT CAAGCCCATG TCTTGAGCAG 
TTTCCTACTA CGTGTGAAAC AGGCCCAGGA AGTCCATCTG GCCACGCAAT GGGCTCATCG 
TGCGTCTGGT ATGTCATGGT AACAGCTGCC CTAAGCTACA CCATCAGCCG GATGGAGGAG 
TCCTCTGTCA CTCTGCACAG ACTGACCTGG TCCTTTCTGT GGAGTGTTTT CTGGTTGATT 
CAAATCAGCG TCTGCATCTC AAGAGTATTC ATAGCCACAC ATTTCCCCCA TCAGGTCATT 
CTTGGAGTGA TTGGTGGGAT GCTAGTAGCC GAGGCCTTTG AACACACTCC AGGAGTCCAC 
ATGGCCAGCT TGAGTGTGTA CCTGAAGACC AACGTCTTCC TCTTCCTGTT TGCCCTCGGC 
TTTTACCTGC TTCTCCGACT GTTCGGTATT GACCTGCTGT GGTCCGTGCC CATCGCCAAA 
AAGTGGTGTG CCAACCCAGA CTGGATCCAC ATTGACAGCA CGCCTTTTGC TGGACTCGTG 
AGAAACCTCG GGGTCCTCTT TGGCTTGGGT TTCGCCATCA ACTCAGAAAT GTTCCTTCGG 
AGCTGCCAGG GAGAAAATGG CACCAAGCCG AGCTTCCGCT TGCTCTGTGC TCTGACCTCA 
CTGACCACAA TGCAACTTTA TCGCTTCATC AAGATCCCGA CTCACGCGGA ACCTTTATTT 
TACCTGTTGT CTTTCTGTAA AAGTGCGTCC ATCCCCCTGA TGGTGGTGGC TCTAATTCCC 
TACTGTGTAC ATATGTTAAT GAGACCCGGT GACAAGAAGA CTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067306.1
CDS	85..1152
Translation	MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK

Target ORF information:

RefSeq Version	NM_021331.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021331.4

ORF Insert Sequence:

ATGGATTTCC TTCATAGGAG TGGAGTGCTT ATTATTCATC ATCTGCAGGA GGACTACCGG 
ACTTACTATG GTTTTCTAAA TTTTATGTCC AATGTTGGAG ACCCCCGAAA TATCTTTTCT 
ATTTACTTCC CACTTTGGTT TCAGTTGAAT CAGAATGTTG GAACCAAGAT GATCTGGGTA 
GCGGTCATAG GGGACTGGTT CAATCTCATA TTTAAATGGA TATTGTTTGG CCATCGTCCT 
TACTGGTGGA TACAAGAAAC TGAGATTTAT CCAAATCATT CAAGCCCATG TCTTGAGCAG 
TTTCCTACTA CGTGTGAAAC AGGCCCAGGA AGTCCATCTG GCCACGCAAT GGGCTCATCG 
TGCGTCTGGT ATGTCATGGT AACAGCTGCC CTAAGCTACA CCATCAGCCG GATGGAGGAG 
TCCTCTGTCA CTCTGCACAG ACTGACCTGG TCCTTTCTGT GGAGTGTTTT CTGGTTGATT 
CAAATCAGCG TCTGCATCTC AAGAGTATTC ATAGCCACAC ATTTCCCCCA TCAGGTCATT 
CTTGGAGTGA TTGGTGGGAT GCTAGTAGCC GAGGCCTTTG AACACACTCC AGGAGTCCAC 
ATGGCCAGCT TGAGTGTGTA CCTGAAGACC AACGTCTTCC TCTTCCTGTT TGCCCTCGGC 
TTTTACCTGC TTCTCCGACT GTTCGGTATT GACCTGCTGT GGTCCGTGCC CATCGCCAAA 
AAGTGGTGTG CCAACCCAGA CTGGATCCAC ATTGACAGCA CGCCTTTTGC TGGACTCGTG 
AGAAACCTCG GGGTCCTCTT TGGCTTGGGT TTCGCCATCA ACTCAGAAAT GTTCCTTCGG 
AGCTGCCAGG GAGAAAATGG CACCAAGCCG AGCTTCCGCT TGCTCTGTGC TCTGACCTCA 
CTGACCACAA TGCAACTTTA TCGCTTCATC AAGATCCCGA CTCACGCGGA ACCTTTATTT 
TACCTGTTGT CTTTCTGTAA AAGTGCGTCC ATCCCCCTGA TGGTGGTGGC TCTAATTCCC 
TACTGTGTAC ATATGTTAAT GAGACCCGGT GACAAGAAGA CTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

G6pc2 ( NM_001289857.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276786.1 Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu23257
Clone ID Related Accession (Same CDS sequence)	NM_001289857.1
Accession Version	NM_001289857.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	glucose-6-phosphatase 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK148450.1 and BP758187.1. On Feb 4, 2014 this sequence version replaced XM_006498754.1. Transcript Variant: This variant (3) differs in the 3' UTR and lacks an alternate exon in the coding region resulting in a frameshift and an early stop codon compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148450.1, BC111905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATTTCC TTCATAGGAG TGGAGTGCTT ATTATTCATC ATCTGCAGGA GGACTACCGG 
ACTTACTATG GTTTTCTAAA TTTTATGTCC AATGTTGGAG ACCCCCGAAA TATCTTTTCT 
ATTTACTTCC CACTTTGGTT TCAGTTGAAT CAGAATGTTG GAACCAAGAT GATCTGGGTA 
GCGGTCATAG GGGACTGGTT CAATCTCATA TTTAAATGGA TATTGTTTGG CCATCGTCCT 
TACTGGTGGA TACAAGAAAC TGAGATTTAT CCAAATCATT CAAGCCCATG TCTTGAGCAG 
TTTCCTACTA CGTGTGAAAC AGGCCCAGGA AGTCCATCTG GCCACGCAAT GGGCTCATCG 
TGCGTCTGGT ATGTCATGGT AACAGCTGCC CTAAGCTACA CCATCAGCCG GATGGAGGAG 
TCCTCTGTCA CTCTGCACAG GGATGCTAGT AGCCGAGGCC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276786.1
CDS	85..549
Translation	MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRDASSRGL

Target ORF information:

RefSeq Version	NM_001289857.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289857.1

ORF Insert Sequence:

ATGGATTTCC TTCATAGGAG TGGAGTGCTT ATTATTCATC ATCTGCAGGA GGACTACCGG 
ACTTACTATG GTTTTCTAAA TTTTATGTCC AATGTTGGAG ACCCCCGAAA TATCTTTTCT 
ATTTACTTCC CACTTTGGTT TCAGTTGAAT CAGAATGTTG GAACCAAGAT GATCTGGGTA 
GCGGTCATAG GGGACTGGTT CAATCTCATA TTTAAATGGA TATTGTTTGG CCATCGTCCT 
TACTGGTGGA TACAAGAAAC TGAGATTTAT CCAAATCATT CAAGCCCATG TCTTGAGCAG 
TTTCCTACTA CGTGTGAAAC AGGCCCAGGA AGTCCATCTG GCCACGCAAT GGGCTCATCG 
TGCGTCTGGT ATGTCATGGT AACAGCTGCC CTAAGCTACA CCATCAGCCG GATGGAGGAG 
TCCTCTGTCA CTCTGCACAG GGATGCTAGT AGCCGAGGCC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

G6pc2 ( NM_001289856.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276785.1 Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23288
Clone ID Related Accession (Same CDS sequence)	NM_001289856.1
Accession Version	NM_001289856.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	glucose-6-phosphatase 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ557220.1, AK148465.1 and BP758187.1. On Feb 4, 2014 this sequence version replaced XM_006498753.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon, lacks a portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ557220.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCTCAT CGTGCGTCTG GTATGTCATG GTAACAGCTG CCCTAAGCTA CACCATCAGC 
CGGATGGAGG AGTCCTCTGT CACTCTGCAC AGACTGACCT GGTCCTTTCT GTGGAGTGTT 
TTCTGGTTGA TTCAAATCAG CGTCTGCATC TCAAGAGTAT TCATAGCCAC ACATTTCCCC 
CATCAGGTCA TTCTTGGAGT GATTGGTGGG ATGCTAGTAG CCGAGGCCTT TGAACACACT 
CCAGGAGTCC ACATGGCCAG CTTGAGTGTG TACCTGAAGA CCAACGTCTT CCTCTTCCTG 
TTTGCCCTCG GCTTTTACCT GCTTCTCCGA CTGTTCGGTA TTGACCTGCT GTGGTCCGTG 
CCCATCGCCA AAAAGTGGTG TGCCAACCCA GACTGGATCC ACATTGACAG CACGCCTTTT 
GCTGGACTCG TGAGAAACCT CGGGGTCCTC TTTGGCTTGG GTTTCGCCAT CAACTCAGAA 
ATGTTCCTTC GGAGCTGCCA GGGAGAAAAT GGCACCAAGC CGAGCTTCCG CTTGCTCTGT 
GCTCTGACCT CACTGACCAC AATGCAACTT TATCGCTTCA TCAAGATCCC GACTCACGCG 
GAACCTTTAT TTTACCTGTT GTCTTTCTGT AAAAGTGCGT CCATCCCCCT GATGGTGGTG 
GCTCTAATTC CCTACTGTGT ACATATGTTA ATGAGACCCG GTGACAAGAA GACTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276785.1
CDS	213..932
Translation	MGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK

Target ORF information:

RefSeq Version	NM_001289856.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289856.1

ORF Insert Sequence:

ATGGGCTCAT CGTGCGTCTG GTATGTCATG GTAACAGCTG CCCTAAGCTA CACCATCAGC 
CGGATGGAGG AGTCCTCTGT CACTCTGCAC AGACTGACCT GGTCCTTTCT GTGGAGTGTT 
TTCTGGTTGA TTCAAATCAG CGTCTGCATC TCAAGAGTAT TCATAGCCAC ACATTTCCCC 
CATCAGGTCA TTCTTGGAGT GATTGGTGGG ATGCTAGTAG CCGAGGCCTT TGAACACACT 
CCAGGAGTCC ACATGGCCAG CTTGAGTGTG TACCTGAAGA CCAACGTCTT CCTCTTCCTG 
TTTGCCCTCG GCTTTTACCT GCTTCTCCGA CTGTTCGGTA TTGACCTGCT GTGGTCCGTG 
CCCATCGCCA AAAAGTGGTG TGCCAACCCA GACTGGATCC ACATTGACAG CACGCCTTTT 
GCTGGACTCG TGAGAAACCT CGGGGTCCTC TTTGGCTTGG GTTTCGCCAT CAACTCAGAA 
ATGTTCCTTC GGAGCTGCCA GGGAGAAAAT GGCACCAAGC CGAGCTTCCG CTTGCTCTGT 
GCTCTGACCT CACTGACCAC AATGCAACTT TATCGCTTCA TCAAGATCCC GACTCACGCG 
GAACCTTTAT TTTACCTGTT GTCTTTCTGT AAAAGTGCGT CCATCCCCCT GATGGTGGTG 
GCTCTAATTC CCTACTGTGT ACATATGTTA ATGAGACCCG GTGACAAGAA GACTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of
Journal of molecular endocrinology58(3)127-139(2017 Apr)
Boortz KA,Syring KE,Pound LD,Mo H,Bastarache L,Oeser JK,McGuinness OP,Denny JC,O'Brien RM

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.
Endocrinology157(11)4133-4145(2016 Nov)
Boortz KA,Syring KE,Lee RA,Dai C,Oeser JK,McGuinness OP,Wang JC,O'Brien RM

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.
Endocrinology157(8)3002-8(2016 Aug)
Boortz KA,Syring KE,Dai C,Pound LD,Oeser JK,Jacobson DA,Wang JC,McGuinness OP,Powers AC,O'Brien RM

?-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.
PloS one11(2)e0150010(2016)
Abdellatif AM,Oishi H,Itagaki T,Jung Y,Shawki HH,Okita Y,Hasegawa Y,Suzuki H,El-Morsy SE,El-Sayed MA,Shoaib MB,Sugiyama F,Takahashi S

The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.
Diabetes53(7)1754-64(2004 Jul)
Frigeri C,Martin CC,Svitek CA,Oeser JK,Hutton JC,Gannon M,O'Brien RM

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G6pc2 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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