Fshr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fshr
Entrez Gene ID	14309
Full Name	follicle stimulating hormone receptor
General protein information	Preferred Names follicle stimulating hormone receptor Names follicle-stimulating hormone receptor follitropin receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_013523.3	NP_038551.3	follicle-stimulating hormone receptor precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FSHR	XP_538488.2
Bos taurus (cattle)	FSHR	NP_776486.1
Rattus norvegicus (Norway rat)	Fshr	NP_954707.1
Homo sapiens (human)	FSHR	NP_000136.2
Pan troglodytes (chimpanzee)	FSHR	XP_525753.2
	FSHR	XP_001114171.1
Danio rerio (zebrafish)	fshr	NP_001001812.1
Mus musculus (house mouse)	Fshr	NP_038551.3
Xenopus tropicalis (tropical clawed frog)	fshr	XP_002935422.1
Gallus gallus (chicken)	FSHR	NP_990410.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes.
Kong D, Guan Q, Li G, Xin W, Qi X, Guo Y, Zhao J, Xu J, Sun S, Gao L
Biochemical and biophysical research communications495(1)587-593(2018 01)

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity.
Soffientini U, Rebourcet D, Abel MH, Lee S, Hamilton G, Fowler PA, Smith LB, O'Shaughnessy PJ
BMC genomics18(1)972(2017 Dec)

Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.
Berthon A, Faucz FR, Espiard S, Drougat L, Bertherat J, Stratakis CA
Human molecular genetics26(18)3495-3507(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mouse chondrocytes and human articular cartilage express functional FSHR. Moreover, FSH can act on chondrocytes and cause genetic changes.
Title: Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes.

Study demonstrates expression of follicle-stimulating hormone receptor (FSHR) and a direct action of follicle-stimulating hormone on testicular stem/germ cells possibly mediated via alternatively spliced growth factor type 1 receptor FSHR3 in mice.
Title: Testicular Stem Cells Express Follicle-Stimulating Hormone Receptors and Are Directly Modulated by FSH.

Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR
Title: Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice.

Brca1(GC-/-) models reveal that specific intra-follicular Brca1 loss alone, or combined with cancer-promoting genetic (Trp53 loss) and endocrine (high serum follicle-stimulating hormone) changes, was not sufficient to cause ovarian tumors.
Title: Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors.

Data (including date from knockout mice) suggest that Fshr is expressed early in pregnany in placenta and other extragonadal tissues of fetoplacental unit; expression is particularly strong at term.
Title: FSH receptor (FSHR) expression in human extragonadal reproductive tissues and the developing placenta, and the impact of its deletion on pregnancy in mice.

The following Fshr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fshr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09539	NM_013523.3 Latest version!	Mus musculus follicle stimulating hormone receptor (Fshr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fshr ( NM_013523.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038551.3 Mus musculus follicle stimulating hormone receptor (Fshr), mRNA.

Price & Availability↑

CloneID	OMu09539
Clone ID Related Accession (Same CDS sequence)	NM_013523.3
Accession Version	NM_013523.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	follicle-stimulating hormone receptor precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC165082.2, BC137990.1 and CT009630.16. On Jul 1, 2009 this sequence version replaced NM_013523.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK016635.1, BC137990.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849384 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTTGC TCCTGGTCTC CTTGCTGGCA TTCTTGGGCT CGGGATCTGG ATGTCATCAC 
TGGCTGTGTC ATTGCTCTAA CAGGGTCTTC CTCTGCCAAG ATAGCAAGGT GACCGAGATT 
CCGCCCGACC TCCCCCGGAA CGCCATTGAA CTGAGATTTG TGCTCACCAA GCTTCGAGTC 
ATTCCAAAAG GATCATTTTC TGGATTTGGG GACCTGGAGA AAATAGAGAT CTCTCAGAAT 
GATGTCTTGG AGGTAATAGA GGCAGATGTG TTCTCCAACC TACCCAACTT GCATGAAATT 
AGGATTGAAA AGGCTAACAA TCTGCTGTAC ATCAACCCTG AGGCCTTCCA GAATCTTCCC 
AGTCTCCGAT ATCTGTTAAT ATCCAACACA GGCATTAAAC ACTTGCCAGC CTTTCACAAG 
ATCCAGTCTC TCCAAAAGGT TTTATTAGAC ATTCAAGATA ACATAAACAT CCACATCATT 
GCCAGGAACT CCTTCATGGG ACTGAGCTTT GAAAGTGTAA TTCTATGGCT GAATAAGAAT 
GGGATTCAAG AAATACACAA CTGTGCATTC AACGGAACCC AGCTAGATGA ACTGAATCTA 
AGCGATAACA ATAATTTGGA AGAATTGCCT GATGATGTTT TCCAGGGAGC CTCTGGGCCA 
GTCGTTTTAG ACATCTCAAG GACAAAGGTC TATTCCCTGC CCAACCATGG CTTAGAAAAT 
CTGAAGAAGT TGAGGGCCAG GTCAACATAC CGCTTGAAAA AGCTCCCTAG TCTAGACAAG 
TTTGTCATGC TCATTGAGGC CAGCCTTACC TACCCCAGTC ACTGCTGTGC CTTTGCAAAC 
TGGAGGCGGC AAACCTCTGA ACTTCATCCA ATTTGCAACA AGTCTATTTC AAGGCAAGAT 
ATTGATGATA TGACTCAGCC TGGGGATCAG AGAGTCTCTC TCGTAGATGA TGAACCCAGT 
TATGGAAAAG GATCTGACAT GTTGTATAGT GAATTTGACT ATGACTTATG CAATGAATTT 
GTTGATGTGA CCTGCTCGCC AAAGCCAGAT GCATTTAATC CATGTGAAGA CATCATGGGG 
TACAACATCC TCAGAGTCTT GATATGGTTT ATCAGCATCC TGGCCATCAC TGGGAACACC 
ACAGTGCTGG TGGTCCTGAC CACAAGCCAA TACAAACTCA CTGTGCCCCG GTTCCTTATG 
TGTAACCTCG CCTTTGCTGA TCTTTGCATT GGGATCTACT TGCTACTTAT AGCCTCAGTT 
GATATCCATA CTAAGAGCCA GTACCACAAT TACGCCATTG ACTGGCAAAC AGGAGCAGGC 
TGCGATGCCG CTGGCTTTTT CACTGTCTTT GCCAGTGAAC TGTCAGTCTA CACATTGGCA 
GCCATAACCC TAGAAAGATG GCATACCATC ACACATGCCA TGCAACTGGA ATGCAAGGTA 
CAGCTCTGCC ATGCTGCCAG CATCATGGTG CTGGGCTGGG CCTTTGCCTT TGCGGCTGCT 
CTCTTCCCCA TCTTTGGCAT CAGTAGCTAC ATGAAAGTGA GCATCTGCCT GCCCATGGAT 
ATCGACAGCC CTTTGTCGCA GCTGTATGTT ATGGCCCTCC TCGTACTCAA CGCCCTGGCC 
TTTGTGGTCA TCTGTGGTTG CTACACCCAC ATCTACCTCA CAGTGAGGAA TCCTAACATT 
GTGTCCTCGT CAAGAGACAC CAAGATTGCC AAGCGCATGG CCACACTCAT CTTCACGGAC 
TTTCTCTGCA TGGCCCCAAT TTTATTCTTT GCCATTTCCG CCTCCCTCAA GGTGCCCCTC 
ATCACTGTGT CCAAGGCCAA GATCCTCCTA GTTCTGTTCT ACCCCATCAA TTCTTGTGCC 
AATCCTTTCC TCTATGCCAT TTTCACCAAG AACTTCCGCA GGGACTTCTT CGTCCTGATG 
AGCAAGTTTG GCTGTTATGA GGTGCAAGCC CAGATTTACA AGACAGAAAC CTCATCTATT 
ACCCACAACT TCCACTCCAG AAAGAATCCC TGTTCCTCGG CTCCCAGAGT CACCAATAGT 
TACGTGCTTG TCCCTCTAAA TCATTCAGTC CAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038551.3
CDS	64..2142
Translation	MALLLVSLLAFLGSGSGCHHWLCHCSNRVFLCQDSKVTEIPPDLPRNAIELRFVLTKLRVIPKGSFSGFGDLEKIEISQNDVLEVIEADVFSNLPNLHEIRIEKANNLLYINPEAFQNLPSLRYLLISNTGIKHLPAFHKIQSLQKVLLDIQDNINIHIIARNSFMGLSFESVILWLNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPDDVFQGASGPVVLDISRTKVYSLPNHGLENLKKLRARSTYRLKKLPSLDKFVMLIEASLTYPSHCCAFANWRRQTSELHPICNKSISRQDIDDMTQPGDQRVSLVDDEPSYGKGSDMLYSEFDYDLCNEFVDVTCSPKPDAFNPCEDIMGYNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLAAITLERWHTITHAMQLECKVQLCHAASIMVLGWAFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMALLVLNALAFVVICGCYTHIYLTVRNPNIVSSSRDTKIAKRMATLIFTDFLCMAPILFFAISASLKVPLITVSKAKILLVLFYPINSCANPFLYAIFTKNFRRDFFVLMSKFGCYEVQAQIYKTETSSITHNFHSRKNPCSSAPRVTNSYVLVPLNHSVQN

Target ORF information:

RefSeq Version	NM_013523.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus follicle stimulating hormone receptor (Fshr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013523.3

ORF Insert Sequence:

ATGGCCTTGC TCCTGGTCTC CTTGCTGGCA TTCTTGGGCT CGGGATCTGG ATGTCATCAC 
TGGCTGTGTC ATTGCTCTAA CAGGGTCTTC CTCTGCCAAG ATAGCAAGGT GACCGAGATT 
CCGCCCGACC TCCCCCGGAA CGCCATTGAA CTGAGATTTG TGCTCACCAA GCTTCGAGTC 
ATTCCAAAAG GATCATTTTC TGGATTTGGG GACCTGGAGA AAATAGAGAT CTCTCAGAAT 
GATGTCTTGG AGGTAATAGA GGCAGATGTG TTCTCCAACC TACCCAACTT GCATGAAATT 
AGGATTGAAA AGGCTAACAA TCTGCTGTAC ATCAACCCTG AGGCCTTCCA GAATCTTCCC 
AGTCTCCGAT ATCTGTTAAT ATCCAACACA GGCATTAAAC ACTTGCCAGC CTTTCACAAG 
ATCCAGTCTC TCCAAAAGGT TTTATTAGAC ATTCAAGATA ACATAAACAT CCACATCATT 
GCCAGGAACT CCTTCATGGG ACTGAGCTTT GAAAGTGTAA TTCTATGGCT GAATAAGAAT 
GGGATTCAAG AAATACACAA CTGTGCATTC AACGGAACCC AGCTAGATGA ACTGAATCTA 
AGCGATAACA ATAATTTGGA AGAATTGCCT GATGATGTTT TCCAGGGAGC CTCTGGGCCA 
GTCGTTTTAG ACATCTCAAG GACAAAGGTC TATTCCCTGC CCAACCATGG CTTAGAAAAT 
CTGAAGAAGT TGAGGGCCAG GTCAACATAC CGCTTGAAAA AGCTCCCTAG TCTAGACAAG 
TTTGTCATGC TCATTGAGGC CAGCCTTACC TACCCCAGTC ACTGCTGTGC CTTTGCAAAC 
TGGAGGCGGC AAACCTCTGA ACTTCATCCA ATTTGCAACA AGTCTATTTC AAGGCAAGAT 
ATTGATGATA TGACTCAGCC TGGGGATCAG AGAGTCTCTC TCGTAGATGA TGAACCCAGT 
TATGGAAAAG GATCTGACAT GTTGTATAGT GAATTTGACT ATGACTTATG CAATGAATTT 
GTTGATGTGA CCTGCTCGCC AAAGCCAGAT GCATTTAATC CATGTGAAGA CATCATGGGG 
TACAACATCC TCAGAGTCTT GATATGGTTT ATCAGCATCC TGGCCATCAC TGGGAACACC 
ACAGTGCTGG TGGTCCTGAC CACAAGCCAA TACAAACTCA CTGTGCCCCG GTTCCTTATG 
TGTAACCTCG CCTTTGCTGA TCTTTGCATT GGGATCTACT TGCTACTTAT AGCCTCAGTT 
GATATCCATA CTAAGAGCCA GTACCACAAT TACGCCATTG ACTGGCAAAC AGGAGCAGGC 
TGCGATGCCG CTGGCTTTTT CACTGTCTTT GCCAGTGAAC TGTCAGTCTA CACATTGGCA 
GCCATAACCC TAGAAAGATG GCATACCATC ACACATGCCA TGCAACTGGA ATGCAAGGTA 
CAGCTCTGCC ATGCTGCCAG CATCATGGTG CTGGGCTGGG CCTTTGCCTT TGCGGCTGCT 
CTCTTCCCCA TCTTTGGCAT CAGTAGCTAC ATGAAAGTGA GCATCTGCCT GCCCATGGAT 
ATCGACAGCC CTTTGTCGCA GCTGTATGTT ATGGCCCTCC TCGTACTCAA CGCCCTGGCC 
TTTGTGGTCA TCTGTGGTTG CTACACCCAC ATCTACCTCA CAGTGAGGAA TCCTAACATT 
GTGTCCTCGT CAAGAGACAC CAAGATTGCC AAGCGCATGG CCACACTCAT CTTCACGGAC 
TTTCTCTGCA TGGCCCCAAT TTTATTCTTT GCCATTTCCG CCTCCCTCAA GGTGCCCCTC 
ATCACTGTGT CCAAGGCCAA GATCCTCCTA GTTCTGTTCT ACCCCATCAA TTCTTGTGCC 
AATCCTTTCC TCTATGCCAT TTTCACCAAG AACTTCCGCA GGGACTTCTT CGTCCTGATG 
AGCAAGTTTG GCTGTTATGA GGTGCAAGCC CAGATTTACA AGACAGAAAC CTCATCTATT 
ACCCACAACT TCCACTCCAG AAAGAATCCC TGTTCCTCGG CTCCCAGAGT CACCAATAGT 
TACGTGCTTG TCCCTCTAAA TCATTCAGTC CAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes.
Biochemical and biophysical research communications495(1)587-593(2018 01)
Kong D,Guan Q,Li G,Xin W,Qi X,Guo Y,Zhao J,Xu J,Sun S,Gao L

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity.
BMC genomics18(1)972(2017 Dec)
Soffientini U,Rebourcet D,Abel MH,Lee S,Hamilton G,Fowler PA,Smith LB,O'Shaughnessy PJ

Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.
Human molecular genetics26(18)3495-3507(2017 Sep)
Berthon A,Faucz FR,Espiard S,Drougat L,Bertherat J,Stratakis CA

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Fshr cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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