Fkbp1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fkbp1b
Entrez Gene ID	14226
Full Name	FK506 binding protein 1b
Synonyms	12.6kDa,AW494148,FKBP12.6,calstabin2
General protein information	Preferred Names FK506 binding protein 1b Names peptidyl-prolyl cis-trans isomerase FKBP1B 12.6 kDa FK506-binding protein 12.6 kDa FKBP FK506-binding protein 12.6 FK506-binding protein 1B FKBP-12.6 FKBP-1B PPIase FKBP1B immunophilin FKBP12.6 rotamase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006514974.3	XP_006515037.2	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1
XM_017314959.1	XP_017170448.1	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2
XM_017314959.2	XP_017170448.1	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2
NM_016863.3	NP_058559.3	peptidyl-prolyl cis-trans isomerase FKBP1B
XM_006514974.4	XP_006515037.3	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1

Pathways from BioSystems

Homologies

	FKBP1B	XP_001098297.1
Bos taurus (cattle)	FKBP1B	NP_001091627.1
Xenopus tropicalis (tropical clawed frog)	fkbp1b	NP_001096492.1
Gallus gallus (chicken)	FKBP1B	NP_989898.1
Homo sapiens (human)	FKBP1B	NP_004107.1
Rattus norvegicus (Norway rat)	Fkbp1b	NP_073166.1
Danio rerio (zebrafish)	fkbp1b	NP_957106.1
Pan troglodytes (chimpanzee)	FKBP1B	XP_001144201.2
Canis lupus familiaris (dog)	FKBP1B	XP_853461.1
Mus musculus (house mouse)	Fkbp1b	NP_058559.3

Gene Ontology
Bibliography

Related articles in PubMed

Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.
Zhao YT, Guo YB, Gu L, Fan XX, Yang HQ, Chen Z, Zhou P, Yuan Q, Ji GJ, Wang SQ
Cardiovascular research113(3)332-342(2017 Mar)

Calstabin 2: An important regulator for learning and memory in mice.
Yuan Q, Deng KY, Sun L, Chi S, Yang Z, Wang J, Xin HB, Wang X, Ji G
Scientific reports621087(2016 Feb)

Functional role of Calstabin2 in age-related cardiac alterations.
Yuan Q, Chen Z, Santulli G, Gu L, Yang ZG, Yuan ZQ, Zhao YT, Xin HB, Deng KY, Wang SQ, Ji G
Scientific reports47425(2014 Dec)

Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.
Wang W, Landstrom AP, Wang Q, Munro ML, Beavers D, Ackerman MJ, Soeller C, Wehrens XH
American journal of physiology. Heart and circulatory physiology307(9)H1317-26(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The heart contraction is controlled by the Ca2+-induced Ca2+ release between L-type Ca2+ channels and ryanodine receptors. RyRs became more sensitive to Ca2+ triggers without FKBP12.6, leading to ventricular arrthymias.
Title: Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.

Calstabin2 as a key modulator of cardiac aging.
Title: Functional role of Calstabin2 in age-related cardiac alterations.

Sirolimus-FKBP12.6 impairs endothelial barrier function by activation of protein kinase C-alpha and downstream disruption of the p120-VE cadherin interaction in vascular endothelium.
Title: Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-? activation and disruption of the p120-vascular endothelial cadherin interaction.

genetic approaches confirm the role of FKBP12.6 in regulating cardiac ryanodine receptors
Title: The role of FK506-binding proteins 12 and 12.6 in regulating cardiac function.

the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 and FKBP12.6, and intracellular calcium dynamics was investigated.
Title: Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics.

The following Fkbp1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fkbp1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10677	NM_016863.3 Latest version!	Mus musculus FK506 binding protein 1b (Fkbp1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu47233	XM_006514974.4 Latest version!	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu78144	XM_006514974.3 Latest version!	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu78145	XM_017314959.2 Latest version!	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu78145	XM_017314959.1	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fkbp1b ( XM_017314959.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170448.1 Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu78145
Clone ID Related Accession (Same CDS sequence)	XM_017314959.1 , XM_017314959.2
Accession Version	XM_017314959.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 240bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCAAA ATGGCAAGAA ATTTGATTCA TCCAGAGACA GAAACAAACC TTTCAAGTTC 
AGAATTGGCA AACAGGAAGT CATCAAAGGC TTTGAAGAAG GCACTGCCCA GATGAGCTTG 
GGGCAGAGGG CGAAGCTGAC CTGCACCCCT GATGTGGCCT ATGGAGCTAC CGGCCACCCC 
GGTGTCATCC CTCCCAATGC CACCCTCATC TTTGACGTGG AGCTGCTCAG CTTAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170448.1
CDS	89..328
Translation	MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE

Target ORF information:

RefSeq Version	XM_017314959.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314959.1

ORF Insert Sequence:

ATGCTTCAAA ATGGCAAGAA ATTTGATTCA TCCAGAGACA GAAACAAACC TTTCAAGTTC 
AGAATTGGCA AACAGGAAGT CATCAAAGGC TTTGAAGAAG GCACTGCCCA GATGAGCTTG 
GGGCAGAGGG CGAAGCTGAC CTGCACCCCT GATGTGGCCT ATGGAGCTAC CGGCCACCCC 
GGTGTCATCC CTCCCAATGC CACCCTCATC TTTGACGTGG AGCTGCTCAG CTTAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp1b ( NM_016863.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058559.3 Mus musculus FK506 binding protein 1b (Fkbp1b), mRNA.

Price & Availability↑

CloneID	OMu10677
Clone ID Related Accession (Same CDS sequence)	NM_016863.3
Accession Version	NM_016863.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP1B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE861051.1, AF060872.1 and BC049596.1. On Jan 19, 2007 this sequence version replaced NM_016863.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC049596.1, BC061121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGGCGTGG AGATCGAGAC CATCTCCCCA GGAGACGGAA GGACATTCCC TAAGAAGGGT 
CAGATATGTG TGGTGCACTA CACAGGAATG CTTCAAAATG GCAAGAAATT TGATTCATCC 
AGAGACAGAA ACAAACCTTT CAAGTTCAGA ATTGGCAAAC AGGAAGTCAT CAAAGGCTTT 
GAAGAAGGCA CTGCCCAGAT GAGCTTGGGG CAGAGGGCGA AGCTGACCTG CACCCCTGAT 
GTGGCCTATG GAGCTACCGG CCACCCCGGT GTCATCCCTC CCAATGCCAC CCTCATCTTT 
GACGTGGAGC TGCTCAGCTT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058559.3
CDS	161..487
Translation	MGVEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE

Target ORF information:

RefSeq Version	NM_016863.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 1b (Fkbp1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016863.3

ORF Insert Sequence:

ATGGGCGTGG AGATCGAGAC CATCTCCCCA GGAGACGGAA GGACATTCCC TAAGAAGGGT 
CAGATATGTG TGGTGCACTA CACAGGAATG CTTCAAAATG GCAAGAAATT TGATTCATCC 
AGAGACAGAA ACAAACCTTT CAAGTTCAGA ATTGGCAAAC AGGAAGTCAT CAAAGGCTTT 
GAAGAAGGCA CTGCCCAGAT GAGCTTGGGG CAGAGGGCGA AGCTGACCTG CACCCCTGAT 
GTGGCCTATG GAGCTACCGG CCACCCCGGT GTCATCCCTC CCAATGCCAC CCTCATCTTT 
GACGTGGAGC TGCTCAGCTT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp1b ( XM_006514974.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515037.3 Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47233
Clone ID Related Accession (Same CDS sequence)	XM_006514974.4
Accession Version	XM_006514974.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006514974.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTTA GTCTGGCCAG GATCCGGAGC AGCCACGTCA GGGTCGCTTC CCTCGGGCTC 
CGCCCCGGCC GACCCCACCT TGTCGCACAG CTCCACCCCG CCGCCCCCTT CCCGGCGGCC 
CCTCCCCGCG CAGGTCCTGA CTCCAGCCGC ACCTCCTCCG GCTCTGCAGT GGCGGCAAGA 
AGGCGAGCGG GAGTGCCTGC GGGGTCCGCG CCAGAGCGGA GCCGGGGTCG GGGCAGCCGC 
GAGGACCCCC TTGGAGGCGG GGCCTGTGGG ACCGTGATGG GCGTGGAGAT CGAGACCATC 
TCCCCAGGAG ACGGAAGGAC ATTCCCTAAG AAGGGTCAGA TATGTGTGGT GCACTACACA 
GGAATGCTTC AAAATGGCAA GAAATTTGAT TCATCCAGAG ACAGAAACAA ACCTTTCAAG 
TTCAGAATTG GCAAACAGGA AGTCATCAAA GGCTTTGAAG AAGGCACTGC CCAGCTGGGT 
CCTCTTTCTC CTCTCCCCAT CTGCCCCCAT CCCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515037.3
CDS	26..544
Translation	MVVSLARIRSSHVRVASLGLRPGRPHLVAQLHPAAPFPAAPPRAGPDSSRTSSGSAVAARRRAGVPAGSAPERSRGRGSREDPLGGGACGTVMGVEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQLGPLSPLPICPHPC

Target ORF information:

RefSeq Version	XM_006514974.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514974.4

ORF Insert Sequence:

ATGGTGGTTA GTCTGGCCAG GATCCGGAGC AGCCACGTCA GGGTCGCTTC CCTCGGGCTC 
CGCCCCGGCC GACCCCACCT TGTCGCACAG CTCCACCCCG CCGCCCCCTT CCCGGCGGCC 
CCTCCCCGCG CAGGTCCTGA CTCCAGCCGC ACCTCCTCCG GCTCTGCAGT GGCGGCAAGA 
AGGCGAGCGG GAGTGCCTGC GGGGTCCGCG CCAGAGCGGA GCCGGGGTCG GGGCAGCCGC 
GAGGACCCCC TTGGAGGCGG GGCCTGTGGG ACCGTGATGG GCGTGGAGAT CGAGACCATC 
TCCCCAGGAG ACGGAAGGAC ATTCCCTAAG AAGGGTCAGA TATGTGTGGT GCACTACACA 
GGAATGCTTC AAAATGGCAA GAAATTTGAT TCATCCAGAG ACAGAAACAA ACCTTTCAAG 
TTCAGAATTG GCAAACAGGA AGTCATCAAA GGCTTTGAAG AAGGCACTGC CCAGCTGGGT 
CCTCTTTCTC CTCTCCCCAT CTGCCCCCAT CCCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp1b ( XM_006514974.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515037.2 Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu78144
Clone ID Related Accession (Same CDS sequence)	XM_006514974.3
Accession Version	XM_006514974.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 243bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006514974.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGTGG AGATCGAGAC CATCTCCCCA GGAGACGGAA GGACATTCCC TAAGAAGGGT 
CAGATATGTG TGGTGCACTA CACAGGAATG CTTCAAAATG GCAAGAAATT TGATTCATCC 
AGAGACAGAA ACAAACCTTT CAAGTTCAGA ATTGGCAAAC AGGAAGTCAT CAAAGGCTTT 
GAAGAAGGCA CTGCCCAGCT GGGTCCTCTT TCTCCTCTCC CCATCTGCCC CCATCCCTGC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515037.2
CDS	171..413
Translation	MGVEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQLGPLSPLPICPHPC

Target ORF information:

RefSeq Version	XM_006514974.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514974.3

ORF Insert Sequence:

ATGGGCGTGG AGATCGAGAC CATCTCCCCA GGAGACGGAA GGACATTCCC TAAGAAGGGT 
CAGATATGTG TGGTGCACTA CACAGGAATG CTTCAAAATG GCAAGAAATT TGATTCATCC 
AGAGACAGAA ACAAACCTTT CAAGTTCAGA ATTGGCAAAC AGGAAGTCAT CAAAGGCTTT 
GAAGAAGGCA CTGCCCAGCT GGGTCCTCTT TCTCCTCTCC CCATCTGCCC CCATCCCTGC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp1b ( XM_017314959.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170448.1 Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu78145
Clone ID Related Accession (Same CDS sequence)	XM_017314959.1 , XM_017314959.2
Accession Version	XM_017314959.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 240bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017314959.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCAAA ATGGCAAGAA ATTTGATTCA TCCAGAGACA GAAACAAACC TTTCAAGTTC 
AGAATTGGCA AACAGGAAGT CATCAAAGGC TTTGAAGAAG GCACTGCCCA GATGAGCTTG 
GGGCAGAGGG CGAAGCTGAC CTGCACCCCT GATGTGGCCT ATGGAGCTAC CGGCCACCCC 
GGTGTCATCC CTCCCAATGC CACCCTCATC TTTGACGTGG AGCTGCTCAG CTTAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170448.1
CDS	139..378
Translation	MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE

Target ORF information:

RefSeq Version	XM_017314959.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 1b (Fkbp1b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314959.2

ORF Insert Sequence:

ATGCTTCAAA ATGGCAAGAA ATTTGATTCA TCCAGAGACA GAAACAAACC TTTCAAGTTC 
AGAATTGGCA AACAGGAAGT CATCAAAGGC TTTGAAGAAG GCACTGCCCA GATGAGCTTG 
GGGCAGAGGG CGAAGCTGAC CTGCACCCCT GATGTGGCCT ATGGAGCTAC CGGCCACCCC 
GGTGTCATCC CTCCCAATGC CACCCTCATC TTTGACGTGG AGCTGCTCAG CTTAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.
Cardiovascular research113(3)332-342(2017 Mar)
Zhao YT,Guo YB,Gu L,Fan XX,Yang HQ,Chen Z,Zhou P,Yuan Q,Ji GJ,Wang SQ

Calstabin 2: An important regulator for learning and memory in mice.
Scientific reports621087(2016 Feb)
Yuan Q,Deng KY,Sun L,Chi S,Yang Z,Wang J,Xin HB,Wang X,Ji G

Functional role of Calstabin2 in age-related cardiac alterations.
Scientific reports47425(2014 Dec)
Yuan Q,Chen Z,Santulli G,Gu L,Yang ZG,Yuan ZQ,Zhao YT,Xin HB,Deng KY,Wang SQ,Ji G

Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.
American journal of physiology. Heart and circulatory physiology307(9)H1317-26(2014 Nov)
Wang W,Landstrom AP,Wang Q,Munro ML,Beavers D,Ackerman MJ,Soeller C,Wehrens XH

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Fkbp1b cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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