Fgf5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fgf5
Entrez Gene ID	14176
Full Name	fibroblast growth factor 5
Synonyms	Fgf-5,HBGF-5,angora,go
General protein information	Preferred Names fibroblast growth factor 5 Names fibroblast growth factor 5 heparin-binding growth factor 5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 E3\|5 47.77 cM
Summary	This gene encodes a secreted protein that is a member of a family of heparin-binding growth factors. The encoded protein regulates cell proliferation, particularly the growth of hair follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001277268.1	NP_001264197.1	fibroblast growth factor 5 isoform 2 precursor
NM_010203.5	NP_034333.1	fibroblast growth factor 5 isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	FGF5	NP_004455.2
Pan troglodytes (chimpanzee)	FGF5	XP_526572.2
Danio rerio (zebrafish)	fgf5	NP_001009561.1
Bos taurus (cattle)	FGF5	NP_001071479.2
Mus musculus (house mouse)	Fgf5	NP_034333.1
	FGF5	XP_001089996.1
Xenopus tropicalis (tropical clawed frog)	fgf5	XP_002934055.1
Rattus norvegicus (Norway rat)	Fgf5	NP_071547.1
Canis lupus familiaris (dog)	FGF5	NP_001041594.1
Gallus gallus (chicken)	FGF5	XP_001233791.2

Gene Ontology
Bibliography

Related articles in PubMed

Functional evolutionary history of the mouse Fgf gene family.
Itoh N, Ornitz DM
Developmental dynamics : an official publication of the American Association of Anatomists237(1)18-27(2008 Jan)

An alternatively spliced fibroblast growth factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity.
Ozawa K, Suzuki S, Asada M, Tomooka Y, Li AJ, Yoneda A, Komi A, Imamura T
The Journal of biological chemistry273(44)29262-71(1998 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It participates in the progression of hepatic fibrosis.
Title: Fibroblast growth factor-5 participates in the progression of hepatic fibrosis.

Interaction of mutant genes Fgf5(go-Y), we, and wal changes the duration of hair growth cycles in mice
Title: [Interaction of mutant genes Fgf5(go-Y), we, and wal changes the duration of hair growth cycles in mice].

A deletion of a 9.3-kb region in the Fgf5 gene showed insertion of a 498-bp early transposon element long terminal repeat. Results show that long hair mutation of moja/moja mice is caused by Fgf5 disruption mediated by retrotransposon insertion.
Title: Retrotransposon-mediated Fgf5(go-Utr) mutant mice with long pelage hair.

Fluctuations of BMP2 signaling pathway during hair cycles in skin with mutant genes we, wal and Fgf5(go).
Title: Fluctuations of BMP signaling pathway during hair cycles in skin of mice with mutant genes we, wal and Fgf5(go).

the Fgf5(go) gene is a powerful modifier of mutant genes determining the process of alopecia.
Title: [The angora gene weakens the effect of interaction of the mutant genes wellhaarig and waved alopecia in mice].

The following Fgf5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgf5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19899	NM_001277268.1 Latest version!	Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu19746	NM_010203.5 Latest version!	Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fgf5 ( NM_001277268.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001264197.1 Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu19899
Clone ID Related Accession (Same CDS sequence)	NM_001277268.1
Accession Version	NM_001277268.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 5 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK028894.1, BC071227.1 and AC125073.4. Transcript Variant: This variant (2, also known as FGF-5S) lacks an alternate exon in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB016516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCCTGT CCTTGCTCTT CCTCATCTTC TGCAGCCACC TGATCCACAG CGCTTGGGCT 
CACGGGGAGA AGCGTCTCAC TCCCGAAGGG CAACCCGCGC CTCCTAGGAA CCCGGGAGAC 
TCCAGCGGCA GCCGGGGCAG AAGTAGCGCG ACGTTTTCTT CGTCTTCTGC CTCCTCACCA 
GTCGCAGCTT CTCCGGGCAG CCAAGGAAGC GGCTCGGAAC ATAGCAGTTT CCAGTGGAGC 
CCTTCGGGGC GCCGGACCGG CAGCCTGTAC TGCAGAGTGG GCATCGGTTT CCATCTGCAG 
ATCTACCCGG ATGGCAAAGT CAATGGCTCC CACGAAGCCA GTGTGTTAAG CCAAATTTAC 
GGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264197.1
CDS	229..594
Translation	MSLSLLFLIFCSHLIHSAWAHGEKRLTPEGQPAPPRNPGDSSGSRGRSSATFSSSSASSPVAASPGSQGSGSEHSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEASVLSQIYG

Target ORF information:

RefSeq Version	NM_001277268.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277268.1

ORF Insert Sequence:

ATGAGCCTGT CCTTGCTCTT CCTCATCTTC TGCAGCCACC TGATCCACAG CGCTTGGGCT 
CACGGGGAGA AGCGTCTCAC TCCCGAAGGG CAACCCGCGC CTCCTAGGAA CCCGGGAGAC 
TCCAGCGGCA GCCGGGGCAG AAGTAGCGCG ACGTTTTCTT CGTCTTCTGC CTCCTCACCA 
GTCGCAGCTT CTCCGGGCAG CCAAGGAAGC GGCTCGGAAC ATAGCAGTTT CCAGTGGAGC 
CCTTCGGGGC GCCGGACCGG CAGCCTGTAC TGCAGAGTGG GCATCGGTTT CCATCTGCAG 
ATCTACCCGG ATGGCAAAGT CAATGGCTCC CACGAAGCCA GTGTGTTAAG CCAAATTTAC 
GGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf5 ( NM_010203.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034333.1 Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19746
Clone ID Related Accession (Same CDS sequence)	NM_010203.5
Accession Version	NM_010203.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 5 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK028894.1, BC071227.1 and AC125073.4. On Mar 27, 2013 this sequence version replaced NM_010203.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071227.1, AK028894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCCTGT CCTTGCTCTT CCTCATCTTC TGCAGCCACC TGATCCACAG CGCTTGGGCT 
CACGGGGAGA AGCGTCTCAC TCCCGAAGGG CAACCCGCGC CTCCTAGGAA CCCGGGAGAC 
TCCAGCGGCA GCCGGGGCAG AAGTAGCGCG ACGTTTTCTT CGTCTTCTGC CTCCTCACCA 
GTCGCAGCTT CTCCGGGCAG CCAAGGAAGC GGCTCGGAAC ATAGCAGTTT CCAGTGGAGC 
CCTTCGGGGC GCCGGACCGG CAGCCTGTAC TGCAGAGTGG GCATCGGTTT CCATCTGCAG 
ATCTACCCGG ATGGCAAAGT CAATGGCTCC CACGAAGCCA GTGTGTTAAG TATTTTGGAA 
ATATTTGCTG TGTCTCAGGG GATTGTAGGA ATACGAGGAG TTTTCAGCAA CAAATTTTTA 
GCGATGTCAA AAAAAGGAAA ACTCCATGCA AGTGCCAAAT TTACGGATGA CTGTAAGTTC 
AGGGAGAGAT TCCAAGAAAA CAGCTATAAT ACCTATGCGT CCGCGATCCA CAGAACTGAA 
AAGACAGGCC GAGAGTGGTA CGTGGCCCTG AACAAGAGAG GGAAAGCCAA GAGAGGCTGC 
AGCCCACGGG TCAAACCCCA ACACGTCTCC ACCCACTTCC TACCCAGGTT CAAGCAGTCC 
GAGCAACCGG AACTTTCCTT CACCGTCACT GTTCCAGAAA AGAAAAAGCC ACCGGTGAAA 
CCAAAGGTGC CCCTGTCGCA GCCTCGCAGA AGTCCCAGCC CAGTGAAGTA CAGACTGAAG 
TTTCGCTTTG GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034333.1
CDS	229..1023
Translation	MSLSLLFLIFCSHLIHSAWAHGEKRLTPEGQPAPPRNPGDSSGSRGRSSATFSSSSASSPVAASPGSQGSGSEHSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEASVLSILEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHVSTHFLPRFKQSEQPELSFTVTVPEKKKPPVKPKVPLSQPRRSPSPVKYRLKFRFG

Target ORF information:

RefSeq Version	NM_010203.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 5 (Fgf5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010203.5

ORF Insert Sequence:

ATGAGCCTGT CCTTGCTCTT CCTCATCTTC TGCAGCCACC TGATCCACAG CGCTTGGGCT 
CACGGGGAGA AGCGTCTCAC TCCCGAAGGG CAACCCGCGC CTCCTAGGAA CCCGGGAGAC 
TCCAGCGGCA GCCGGGGCAG AAGTAGCGCG ACGTTTTCTT CGTCTTCTGC CTCCTCACCA 
GTCGCAGCTT CTCCGGGCAG CCAAGGAAGC GGCTCGGAAC ATAGCAGTTT CCAGTGGAGC 
CCTTCGGGGC GCCGGACCGG CAGCCTGTAC TGCAGAGTGG GCATCGGTTT CCATCTGCAG 
ATCTACCCGG ATGGCAAAGT CAATGGCTCC CACGAAGCCA GTGTGTTAAG TATTTTGGAA 
ATATTTGCTG TGTCTCAGGG GATTGTAGGA ATACGAGGAG TTTTCAGCAA CAAATTTTTA 
GCGATGTCAA AAAAAGGAAA ACTCCATGCA AGTGCCAAAT TTACGGATGA CTGTAAGTTC 
AGGGAGAGAT TCCAAGAAAA CAGCTATAAT ACCTATGCGT CCGCGATCCA CAGAACTGAA 
AAGACAGGCC GAGAGTGGTA CGTGGCCCTG AACAAGAGAG GGAAAGCCAA GAGAGGCTGC 
AGCCCACGGG TCAAACCCCA ACACGTCTCC ACCCACTTCC TACCCAGGTT CAAGCAGTCC 
GAGCAACCGG AACTTTCCTT CACCGTCACT GTTCCAGAAA AGAAAAAGCC ACCGGTGAAA 
CCAAAGGTGC CCCTGTCGCA GCCTCGCAGA AGTCCCAGCC CAGTGAAGTA CAGACTGAAG 
TTTCGCTTTG GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional evolutionary history of the mouse Fgf gene family.
Developmental dynamics : an official publication of the American Association of Anatomists237(1)18-27(2008 Jan)
Itoh N,Ornitz DM

An alternatively spliced fibroblast growth factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity.
The Journal of biological chemistry273(44)29262-71(1998 Oct)
Ozawa K,Suzuki S,Asada M,Tomooka Y,Li AJ,Yoneda A,Komi A,Imamura T

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Fgf5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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