Fgd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fgd1
Entrez Gene ID	14163
Full Name	FYVE, RhoGEF and PH domain containing 1
Synonyms	ZFYVE3
General protein information	Preferred Names FYVE, RhoGEF and PH domain containing 1 Names FYVE, RhoGEF and PH domain-containing protein 1 faciogenital dysplasia 1 protein homolog rho/Rac GEF rho/Rac guanine nucleotide exchange factor FGD1 zinc finger FYVE domain-containing protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F3\|X 68.46 cM
Summary	This gene encodes a member of family of Rho-specific guanine nucleotide exchange factors. Rho-specific guanine nucleotide exchange factors catalyze the exchange of GDP for GTP and activate small GTPases, which function as molecular switches in signaling. This protein specifically binds cell division cycle 42, a Rho (Ras homology) GTPase. Investigations in mouse suggest that this protein is important for skeletal mineralization and for regulating the actin cytoskeleton. In humans, mutations in this gene are associated with faciogenital dysplasia, also known as Aarskog-Scott syndrome. [provided by RefSeq, Mar 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006528699.3	XP_006528762.1	FYVE, RhoGEF and PH domain-containing protein 1 isoform X1
NM_008001.4	NP_032027.2	FYVE, RhoGEF and PH domain-containing protein 1
XM_006528699.4	XP_006528762.1	FYVE, RhoGEF and PH domain-containing protein 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Fgd1	NP_001032635.1
	FGD1	XP_002806297.1
Bos taurus (cattle)	FGD1	NP_001096014.1
Mus musculus (house mouse)	Fgd1	NP_032027.2
Homo sapiens (human)	FGD1	NP_004454.2
Pan troglodytes (chimpanzee)	FGD1	XP_003317524.1
Canis lupus familiaris (dog)	FGD1	XP_549021.2
Xenopus tropicalis (tropical clawed frog)	fgd1	XP_004914246.1
Danio rerio (zebrafish)	fgd1	XP_688794.3

Gene Ontology
Bibliography

Related articles in PubMed

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.
Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH
The Journal of clinical investigation121(11)4383-92(2011 Nov)

Faciogenital dysplasia protein (FGD1) regulates export of cargo proteins from the golgi complex via Cdc42 activation.
Egorov MV, Capestrano M, Vorontsova OA, Di Pentima A, Egorova AV, Mariggi? S, Ayala MI, Tet? S, Gorski JL, Luini A, Buccione R, Polishchuk RS
Molecular biology of the cell20(9)2413-27(2009 May)

Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.
Hayakawa M, Matsushima M, Hagiwara H, Oshima T, Fujino T, Ando K, Kikugawa K, Tanaka H, Miyazawa K, Kitagawa M
Genes to cells : devoted to molecular & cellular mechanisms13(4)329-42(2008 Apr)

Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.
Kostenko EV, Olabisi OO, Sahay S, Rodriguez PL, Whitehead IP
Molecular and cellular biology26(23)8964-75(2006 Dec)

Effect of Fgd1 on cortactin in Arp2/3 complex-mediated actin assembly.
Kim K, Hou P, Gorski JL, Cooper JA
Biochemistry43(9)2422-7(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

activation of MLK3 specifically by FGD1/CDC42 is important for skeletal mineralization
Title: MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.

FGD1 is preferentially associated with the trans-Golgi network (TGN), suggesting its involvement in export of proteins from the Golgi.
Title: Faciogenital dysplasia protein (FGD1) regulates export of cargo proteins from the golgi complex via Cdc42 activation.

this study provides novel in vitro and in vivo evidence that Fgd1 specifically and directly interacts with cortactin and mAbp1, and that these interactions play an important role in regulating the actin cytoskeleton and, subsequently, cell shape.
Title: Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.

The following Fgd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13801	NM_008001.4 Latest version!	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$566.30 $809.00
OMu56586	XM_006528699.4 Latest version!	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu56586	XM_006528699.3	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fgd1 ( NM_008001.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032027.2 Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), mRNA.

Price & Availability↑

CloneID	OMu13801
Clone ID Related Accession (Same CDS sequence)	NM_008001.4
Accession Version	NM_008001.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	FYVE, RhoGEF and PH domain-containing protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA328503.1, CN702035.1, CN531569.1, AK148151.1, AV367660.2 and AI195396.1. On May 22, 2013 this sequence version replaced NM_008001.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148151.1, BC011462.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCATGGCC ACCGAGTCCC GGGGGGCCCT GGGCCTTCGG ATCCCGAACG CTCAGCGGCA 
AATACCCCCG GTGCCGCTCC GCTGGCCTGT GCCGACTCGG ACCCTGGAGC CTTGGAACCC 
GGGCTGCCGG TGAGCAGGGG CTCAGGCACG GCTCTTGGAG GCCCTTTGGA TCCTCAGTTT 
GTTGGACCCT CGGATGCCAG CCTGGGAGCG CCTCCAAGCT CCCGGGTCTT ACCCTGCGGC 
CCTAGTCCTC AGCACCACCG GGCCCTGCGC TTCTCCTACC ACCTGGAGGG CTCGCAGCCT 
CGGCCTGGAC TGCACCAGGG AAACCGGATC CTGGTTAAAA GTTTGTCCCT TGACCCTGGC 
CAGAGCCTTG AGCCTCATCC AGAAGGTCCC CAACGGCTTC GCTCAGATCC AGGCCCTCCC 
ACTGAAATCC CTGGCCCACG TCCTTCACCA CTGAAGCGGG CACCGGGCCC AAAGCCACAG 
GTTCCCCCAA AGCCCAGCTA CCTGCAGATG CCCCGGGTGC TTCCTCCTCC TGAGCCCATT 
CCTCCACCAC CATCACGCCC TCTGCCTGCA GACCCTAGAG TGGCCAAGGG ACTCGTCCCC 
AGAGCTGAGG CCAGCACTAG TTCTGCAGCA GTATCATCAT TGATTGAGAA GTTTGAAAGA 
GAGCCTGTGA TTGTTGCCTC GGATAGGCCA GCCCCTGGCC CCTGCCCAGT TCCCCCAGAG 
CCAGCCATGT TGCCACAGCC ACCCCCGCAG CCAACAGGGT CCCAGCTCCC TGAGGGTGAA 
GCTTCTCGCT GCCTGTTCCT GCTGGCTCCT GGGCCCCGGG ATGGTGAGAA GGTGCCTAAC 
CGGGACAGCG GCATTGACAG CATCAGCTCG CCATCCAACA GTGAAGAGAC CTGCTTCGTC 
AGTGATGATG GGCCCCCCAT CCACAGCCTC TGTCCTGGGC CCCCCGCCCT GGCTAGTATG 
CCAGTAGCTT TGGCCGACCC CCACCGGCCT GGCTCCCAGG AGGTTGACAG TGACCTGGAA 
GAGGAAGAGG AAGAAGAAGA GGAGGAAAAG GAAAGAGAAA TTCCAGTGCC CCCGATGGAG 
AGACAGGAGT CTGTGGAGCT GACTGTGCAG CAGAAGGTGT TCCATATTGC CAATGAGCTC 
CTGCAAACTG AGAAGGCCTA TGTTTCCAGG CTCCATCTCC TGGATCAGGT ATTCTGTGCC 
CGGCTGCTGG AAGAAGCTCG GAACCGCAGT TCCTTCCCCG CAGATGTTGT CCACGGCATC 
TTCTCTAACA TCTGCTCCAT CTATTGCTTC CACCAGCAGT TCCTGCTGCC TGAGCTAGAG 
AAGCGCATGG AGGAATGGGA CCGCTACCCA CGCATTGGTG ACATTCTTCA GAAGTTGGCA 
CCCTTCCTCA AGATGTATGG CGAGTATGTG AAAAACTTCG ACCGGGCGGT AGAGCTGGTC 
AACACATGGA CAGAGCGGTC TACCCAGTTT AAAGTCATCA TCCATGAAGT ACAGAAGGAG 
GAAGCCTGTG GCAACCTGAC CTTGCAGCAC CACATGCTGG AGCCCGTGCA GCGTATCCCC 
CGCTATGAAC TTCTTCTCAA GGACTATCTG TTAAAGCTGC CTCATGGCTC CCCGGACAGC 
AAGGATGCCC AGAAGTCTTT GGAGCTGATA GCCACAGCAG CAGAACACTC TAATGCTGCC 
ATCCGGAAAA TGGAACGAAT GCACAAGCTG CTGAAGGTGT ATGAGCTGCT AGGGGGTGAG 
GAGGACATTG TCAGTCCCAC CAAAGAGCTC ATAAAGGAAG GCCATATCCT TAAGCTGTCA 
GCAAAGAATG GGACCACTCA AGATCGATAC CTCATATTAT TCAACGACCG CCTCCTTTAC 
TGCGTGCCCA GGCTGCGGCT CCTTGGTCAG AAGTTTAGCG TGCGGGCACG CATTGATGTA 
GATGGCATGG AGCTAAAGGA GAGCTCCAAC CTCAACATGC CTCGGACCTT CCTGGTGTCA 
GGAAAGCAGC GCTCTCTCGA ACTGCAGGCC AGGACTGAGG AGGAGAAGAA AGACTGGGTC 
CAGGCCATCA ATTCCACCCT CCTGAAGCAT GAACAGACCC TGGAGACTTT CAAACTGTTG 
AACTCAACAA ACAGGGATGA TGAAGATACT CCCCCTAACT CTCCAAACGT GGATCTTGGG 
AAGAGGGCAC CTACGCCTAT CCGGGAAAAG GAAGTCACCA TGTGCATGCG CTGCCAGGAG 
CCCTTCAATT CCATCACCAA ACGCAGGCAC CACTGCAAGG CCTGTGGGCA TGTGGTTTGT 
GGGAAATGCT CTGAGTTCCG AGCCCGACTC ATCTATGACA ACAATCGTTC CAACCGTGTG 
TGCACTGATT GCTATGTGGC CTTGCATGGA GCACCTGGGA GCAGTCCAGC CTGTAGCCAG 
CATACACCCC AGCGCAGGAG GTCCATCCTA GAGAAACAGG CCTCGGTCGC TGCTGAGAAC 
AGCGTCATCT GCAGCTTCCT GCACTACATG GAGAAGGGTG GGAAAGGATG GCACAAGGCA 
TGGTTTGTGG TTCCTGAGAA TGAACCCTTG GTGCTGTACA TCTATGGAGC CCCTCAGGAT 
GTGAAAGCCC AGCGCAGCCT GCCCCTCATT GGCTTTGAGG TGGGGCCTCC TGAGGCAGGA 
GAGCGGCCAG ACAGGAGGCA TGTCTTCAAG ATCACACAAA GCCACCTAAG CTGGTACTTC 
AGCCCAGAGA CAGAAGAACT CCAGCGGCGC TGGATGGCTG TTCTCGGCAG GGCGGGCCGT 
GGGGACACAT TCTGCCCAGG GCCCACACTG TCTGAGGACA AGGAGATGGA GGAGACACCA 
GTGGCAGCCT CAGGAGCCAC TGCTGAACCT CCTGAAGCCT CCCAGACCCG AGACAAGACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032027.2
CDS	506..3388
Translation	MHGHRVPGGPGPSDPERSAANTPGAAPLACADSDPGALEPGLPVSRGSGTALGGPLDPQFVGPSDASLGAPPSSRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQRLRSDPGPPTEIPGPRPSPLKRAPGPKPQVPPKPSYLQMPRVLPPPEPIPPPPSRPLPADPRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPEPAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDLEEEEEEEEEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAASGATAEPPEASQTRDKT

Target ORF information:

RefSeq Version	NM_008001.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008001.4

ORF Insert Sequence:

ATGCATGGCC ACCGAGTCCC GGGGGGCCCT GGGCCTTCGG ATCCCGAACG CTCAGCGGCA 
AATACCCCCG GTGCCGCTCC GCTGGCCTGT GCCGACTCGG ACCCTGGAGC CTTGGAACCC 
GGGCTGCCGG TGAGCAGGGG CTCAGGCACG GCTCTTGGAG GCCCTTTGGA TCCTCAGTTT 
GTTGGACCCT CGGATGCCAG CCTGGGAGCG CCTCCAAGCT CCCGGGTCTT ACCCTGCGGC 
CCTAGTCCTC AGCACCACCG GGCCCTGCGC TTCTCCTACC ACCTGGAGGG CTCGCAGCCT 
CGGCCTGGAC TGCACCAGGG AAACCGGATC CTGGTTAAAA GTTTGTCCCT TGACCCTGGC 
CAGAGCCTTG AGCCTCATCC AGAAGGTCCC CAACGGCTTC GCTCAGATCC AGGCCCTCCC 
ACTGAAATCC CTGGCCCACG TCCTTCACCA CTGAAGCGGG CACCGGGCCC AAAGCCACAG 
GTTCCCCCAA AGCCCAGCTA CCTGCAGATG CCCCGGGTGC TTCCTCCTCC TGAGCCCATT 
CCTCCACCAC CATCACGCCC TCTGCCTGCA GACCCTAGAG TGGCCAAGGG ACTCGTCCCC 
AGAGCTGAGG CCAGCACTAG TTCTGCAGCA GTATCATCAT TGATTGAGAA GTTTGAAAGA 
GAGCCTGTGA TTGTTGCCTC GGATAGGCCA GCCCCTGGCC CCTGCCCAGT TCCCCCAGAG 
CCAGCCATGT TGCCACAGCC ACCCCCGCAG CCAACAGGGT CCCAGCTCCC TGAGGGTGAA 
GCTTCTCGCT GCCTGTTCCT GCTGGCTCCT GGGCCCCGGG ATGGTGAGAA GGTGCCTAAC 
CGGGACAGCG GCATTGACAG CATCAGCTCG CCATCCAACA GTGAAGAGAC CTGCTTCGTC 
AGTGATGATG GGCCCCCCAT CCACAGCCTC TGTCCTGGGC CCCCCGCCCT GGCTAGTATG 
CCAGTAGCTT TGGCCGACCC CCACCGGCCT GGCTCCCAGG AGGTTGACAG TGACCTGGAA 
GAGGAAGAGG AAGAAGAAGA GGAGGAAAAG GAAAGAGAAA TTCCAGTGCC CCCGATGGAG 
AGACAGGAGT CTGTGGAGCT GACTGTGCAG CAGAAGGTGT TCCATATTGC CAATGAGCTC 
CTGCAAACTG AGAAGGCCTA TGTTTCCAGG CTCCATCTCC TGGATCAGGT ATTCTGTGCC 
CGGCTGCTGG AAGAAGCTCG GAACCGCAGT TCCTTCCCCG CAGATGTTGT CCACGGCATC 
TTCTCTAACA TCTGCTCCAT CTATTGCTTC CACCAGCAGT TCCTGCTGCC TGAGCTAGAG 
AAGCGCATGG AGGAATGGGA CCGCTACCCA CGCATTGGTG ACATTCTTCA GAAGTTGGCA 
CCCTTCCTCA AGATGTATGG CGAGTATGTG AAAAACTTCG ACCGGGCGGT AGAGCTGGTC 
AACACATGGA CAGAGCGGTC TACCCAGTTT AAAGTCATCA TCCATGAAGT ACAGAAGGAG 
GAAGCCTGTG GCAACCTGAC CTTGCAGCAC CACATGCTGG AGCCCGTGCA GCGTATCCCC 
CGCTATGAAC TTCTTCTCAA GGACTATCTG TTAAAGCTGC CTCATGGCTC CCCGGACAGC 
AAGGATGCCC AGAAGTCTTT GGAGCTGATA GCCACAGCAG CAGAACACTC TAATGCTGCC 
ATCCGGAAAA TGGAACGAAT GCACAAGCTG CTGAAGGTGT ATGAGCTGCT AGGGGGTGAG 
GAGGACATTG TCAGTCCCAC CAAAGAGCTC ATAAAGGAAG GCCATATCCT TAAGCTGTCA 
GCAAAGAATG GGACCACTCA AGATCGATAC CTCATATTAT TCAACGACCG CCTCCTTTAC 
TGCGTGCCCA GGCTGCGGCT CCTTGGTCAG AAGTTTAGCG TGCGGGCACG CATTGATGTA 
GATGGCATGG AGCTAAAGGA GAGCTCCAAC CTCAACATGC CTCGGACCTT CCTGGTGTCA 
GGAAAGCAGC GCTCTCTCGA ACTGCAGGCC AGGACTGAGG AGGAGAAGAA AGACTGGGTC 
CAGGCCATCA ATTCCACCCT CCTGAAGCAT GAACAGACCC TGGAGACTTT CAAACTGTTG 
AACTCAACAA ACAGGGATGA TGAAGATACT CCCCCTAACT CTCCAAACGT GGATCTTGGG 
AAGAGGGCAC CTACGCCTAT CCGGGAAAAG GAAGTCACCA TGTGCATGCG CTGCCAGGAG 
CCCTTCAATT CCATCACCAA ACGCAGGCAC CACTGCAAGG CCTGTGGGCA TGTGGTTTGT 
GGGAAATGCT CTGAGTTCCG AGCCCGACTC ATCTATGACA ACAATCGTTC CAACCGTGTG 
TGCACTGATT GCTATGTGGC CTTGCATGGA GCACCTGGGA GCAGTCCAGC CTGTAGCCAG 
CATACACCCC AGCGCAGGAG GTCCATCCTA GAGAAACAGG CCTCGGTCGC TGCTGAGAAC 
AGCGTCATCT GCAGCTTCCT GCACTACATG GAGAAGGGTG GGAAAGGATG GCACAAGGCA 
TGGTTTGTGG TTCCTGAGAA TGAACCCTTG GTGCTGTACA TCTATGGAGC CCCTCAGGAT 
GTGAAAGCCC AGCGCAGCCT GCCCCTCATT GGCTTTGAGG TGGGGCCTCC TGAGGCAGGA 
GAGCGGCCAG ACAGGAGGCA TGTCTTCAAG ATCACACAAA GCCACCTAAG CTGGTACTTC 
AGCCCAGAGA CAGAAGAACT CCAGCGGCGC TGGATGGCTG TTCTCGGCAG GGCGGGCCGT 
GGGGACACAT TCTGCCCAGG GCCCACACTG TCTGAGGACA AGGAGATGGA GGAGACACCA 
GTGGCAGCCT CAGGAGCCAC TGCTGAACCT CCTGAAGCCT CCCAGACCCG AGACAAGACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgd1 ( XM_006528699.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006528762.1 Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu56586
Clone ID Related Accession (Same CDS sequence)	XM_006528699.3 , XM_006528699.4
Accession Version	XM_006528699.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	FYVE, RhoGEF and PH domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006528699.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGGG TGCTTCCTCC TCCTGAGCCC ATTCCTCCAC CACCATCACG CCCTCTGCCT 
GCAGACCCTA GAGTGGCCAA GGGACTCGTC CCCAGAGCTG AGGCCAGCAC TAGTTCTGCA 
GCAGTATCAT CATTGATTGA GAAGTTTGAA AGAGAGCCTG TGATTGTTGC CTCGGATAGG 
CCAGCCCCTG GCCCCTGCCC AGTTCCCCCA GAGCCAGCCA TGTTGCCACA GCCACCCCCG 
CAGCCAACAG GGTCCCAGCT CCCTGAGGGT GAAGCTTCTC GCTGCCTGTT CCTGCTGGCT 
CCTGGGCCCC GGGATGGTGA GAAGGTGCCT AACCGGGACA GCGGCATTGA CAGCATCAGC 
TCGCCATCCA ACAGTGAAGA GACCTGCTTC GTCAGTGATG ATGGGCCCCC CATCCACAGC 
CTCTGTCCTG GGCCCCCCGC CCTGGCTAGT ATGCCAGTAG CTTTGGCCGA CCCCCACCGG 
CCTGGCTCCC AGGAGGTTGA CAGTGACCTG GAAGAGGAAG AGGAAGAAGA AGAGGAGGAA 
AAGGAAAGAG AAATTCCAGT GCCCCCGATG GAGAGACAGG AGTCTGTGGA GCTGACTGTG 
CAGCAGAAGG TGTTCCATAT TGCCAATGAG CTCCTGCAAA CTGAGAAGGC CTATGTTTCC 
AGGCTCCATC TCCTGGATCA GGTATTCTGT GCCCGGCTGC TGGAAGAAGC TCGGAACCGC 
AGTTCCTTCC CCGCAGATGT TGTCCACGGC ATCTTCTCTA ACATCTGCTC CATCTATTGC 
TTCCACCAGC AGTTCCTGCT GCCTGAGCTA GAGAAGCGCA TGGAGGAATG GGACCGCTAC 
CCACGCATTG GTGACATTCT TCAGAAGTTG GCACCCTTCC TCAAGATGTA TGGCGAGTAT 
GTGAAAAACT TCGACCGGGC GGTAGAGCTG GTCAACACAT GGACAGAGCG GTCTACCCAG 
TTTAAAGTCA TCATCCATGA AGTACAGAAG GAGGAAGCCT GTGGCAACCT GACCTTGCAG 
CACCACATGC TGGAGCCCGT GCAGCGTATC CCCCGCTATG AACTTCTTCT CAAGGACTAT 
CTGTTAAAGC TGCCTCATGG CTCCCCGGAC AGCAAGGATG CCCAGAAGTC TTTGGAGCTG 
ATAGCCACAG CAGCAGAACA CTCTAATGCT GCCATCCGGA AAATGGAACG AATGCACAAG 
CTGCTGAAGG TGTATGAGCT GCTAGGGGGT GAGGAGGACA TTGTCAGTCC CACCAAAGAG 
CTCATAAAGG AAGGCCATAT CCTTAAGCTG TCAGCAAAGA ATGGGACCAC TCAAGATCGA 
TACCTCATAT TATTCAACGA CCGCCTCCTT TACTGCGTGC CCAGGCTGCG GCTCCTTGGT 
CAGAAGTTTA GCGTGCGGGC ACGCATTGAT GTAGATGGCA TGGAGCTAAA GGAGAGCTCC 
AACCTCAACA TGCCTCGGAC CTTCCTGGTG TCAGGAAAGC AGCGCTCTCT CGAACTGCAG 
GCCAGGACTG AGGAGGAGAA GAAAGACTGG GTCCAGGCCA TCAATTCCAC CCTCCTGAAG 
CATGAACAGA CCCTGGAGAC TTTCAAACTG TTGAACTCAA CAAACAGGGA TGATGAAGAT 
ACTCCCCCTA ACTCTCCAAA CGTGGATCTT GGGAAGAGGG CACCTACGCC TATCCGGGAA 
AAGGAAGTCA CCATGTGCAT GCGCTGCCAG GAGCCCTTCA ATTCCATCAC CAAACGCAGG 
CACCACTGCA AGGCCTGTGG GCATGTGGTT TGTGGGAAAT GCTCTGAGTT CCGAGCCCGA 
CTCATCTATG ACAACAATCG TTCCAACCGT GTGTGCACTG ATTGCTATGT GGCCTTGCAT 
GGAGCACCTG GGAGCAGTCC AGCCTGTAGC CAGCATACAC CCCAGCGCAG GAGGTCCATC 
CTAGAGAAAC AGGCCTCGGT CGCTGCTGAG AACAGCGTCA TCTGCAGCTT CCTGCACTAC 
ATGGAGAAGG GTGGGAAAGG ATGGCACAAG GCATGGTTTG TGGTTCCTGA GAATGAACCC 
TTGGTGCTGT ACATCTATGG AGCCCCTCAG GATGTGAAAG CCCAGCGCAG CCTGCCCCTC 
ATTGGCTTTG AGGTGGGGCC TCCTGAGGCA GGAGAGCGGC CAGACAGGAG GCATGTCTTC 
AAGATCACAC AAAGCCACCT AAGCTGGTAC TTCAGCCCAG AGACAGAAGA ACTCCAGCGG 
CGCTGGATGG CTGTTCTCGG CAGGGCGGGC CGTGGGGACA CATTCTGCCC AGGGCCCACA 
CTGTCTGAGG ACAAGGAGAT GGAGGAGACA CCAGTGGCAG CCTCAGGAGC CACTGCTGAA 
CCTCCTGAAG CCTCCCAGAC CCGAGACAAG ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006528762.1
CDS	284..2659
Translation	MPRVLPPPEPIPPPPSRPLPADPRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPEPAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDLEEEEEEEEEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAASGATAEPPEASQTRDKT

Target ORF information:

RefSeq Version	XM_006528699.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006528699.3

ORF Insert Sequence:

ATGCCCCGGG TGCTTCCTCC TCCTGAGCCC ATTCCTCCAC CACCATCACG CCCTCTGCCT 
GCAGACCCTA GAGTGGCCAA GGGACTCGTC CCCAGAGCTG AGGCCAGCAC TAGTTCTGCA 
GCAGTATCAT CATTGATTGA GAAGTTTGAA AGAGAGCCTG TGATTGTTGC CTCGGATAGG 
CCAGCCCCTG GCCCCTGCCC AGTTCCCCCA GAGCCAGCCA TGTTGCCACA GCCACCCCCG 
CAGCCAACAG GGTCCCAGCT CCCTGAGGGT GAAGCTTCTC GCTGCCTGTT CCTGCTGGCT 
CCTGGGCCCC GGGATGGTGA GAAGGTGCCT AACCGGGACA GCGGCATTGA CAGCATCAGC 
TCGCCATCCA ACAGTGAAGA GACCTGCTTC GTCAGTGATG ATGGGCCCCC CATCCACAGC 
CTCTGTCCTG GGCCCCCCGC CCTGGCTAGT ATGCCAGTAG CTTTGGCCGA CCCCCACCGG 
CCTGGCTCCC AGGAGGTTGA CAGTGACCTG GAAGAGGAAG AGGAAGAAGA AGAGGAGGAA 
AAGGAAAGAG AAATTCCAGT GCCCCCGATG GAGAGACAGG AGTCTGTGGA GCTGACTGTG 
CAGCAGAAGG TGTTCCATAT TGCCAATGAG CTCCTGCAAA CTGAGAAGGC CTATGTTTCC 
AGGCTCCATC TCCTGGATCA GGTATTCTGT GCCCGGCTGC TGGAAGAAGC TCGGAACCGC 
AGTTCCTTCC CCGCAGATGT TGTCCACGGC ATCTTCTCTA ACATCTGCTC CATCTATTGC 
TTCCACCAGC AGTTCCTGCT GCCTGAGCTA GAGAAGCGCA TGGAGGAATG GGACCGCTAC 
CCACGCATTG GTGACATTCT TCAGAAGTTG GCACCCTTCC TCAAGATGTA TGGCGAGTAT 
GTGAAAAACT TCGACCGGGC GGTAGAGCTG GTCAACACAT GGACAGAGCG GTCTACCCAG 
TTTAAAGTCA TCATCCATGA AGTACAGAAG GAGGAAGCCT GTGGCAACCT GACCTTGCAG 
CACCACATGC TGGAGCCCGT GCAGCGTATC CCCCGCTATG AACTTCTTCT CAAGGACTAT 
CTGTTAAAGC TGCCTCATGG CTCCCCGGAC AGCAAGGATG CCCAGAAGTC TTTGGAGCTG 
ATAGCCACAG CAGCAGAACA CTCTAATGCT GCCATCCGGA AAATGGAACG AATGCACAAG 
CTGCTGAAGG TGTATGAGCT GCTAGGGGGT GAGGAGGACA TTGTCAGTCC CACCAAAGAG 
CTCATAAAGG AAGGCCATAT CCTTAAGCTG TCAGCAAAGA ATGGGACCAC TCAAGATCGA 
TACCTCATAT TATTCAACGA CCGCCTCCTT TACTGCGTGC CCAGGCTGCG GCTCCTTGGT 
CAGAAGTTTA GCGTGCGGGC ACGCATTGAT GTAGATGGCA TGGAGCTAAA GGAGAGCTCC 
AACCTCAACA TGCCTCGGAC CTTCCTGGTG TCAGGAAAGC AGCGCTCTCT CGAACTGCAG 
GCCAGGACTG AGGAGGAGAA GAAAGACTGG GTCCAGGCCA TCAATTCCAC CCTCCTGAAG 
CATGAACAGA CCCTGGAGAC TTTCAAACTG TTGAACTCAA CAAACAGGGA TGATGAAGAT 
ACTCCCCCTA ACTCTCCAAA CGTGGATCTT GGGAAGAGGG CACCTACGCC TATCCGGGAA 
AAGGAAGTCA CCATGTGCAT GCGCTGCCAG GAGCCCTTCA ATTCCATCAC CAAACGCAGG 
CACCACTGCA AGGCCTGTGG GCATGTGGTT TGTGGGAAAT GCTCTGAGTT CCGAGCCCGA 
CTCATCTATG ACAACAATCG TTCCAACCGT GTGTGCACTG ATTGCTATGT GGCCTTGCAT 
GGAGCACCTG GGAGCAGTCC AGCCTGTAGC CAGCATACAC CCCAGCGCAG GAGGTCCATC 
CTAGAGAAAC AGGCCTCGGT CGCTGCTGAG AACAGCGTCA TCTGCAGCTT CCTGCACTAC 
ATGGAGAAGG GTGGGAAAGG ATGGCACAAG GCATGGTTTG TGGTTCCTGA GAATGAACCC 
TTGGTGCTGT ACATCTATGG AGCCCCTCAG GATGTGAAAG CCCAGCGCAG CCTGCCCCTC 
ATTGGCTTTG AGGTGGGGCC TCCTGAGGCA GGAGAGCGGC CAGACAGGAG GCATGTCTTC 
AAGATCACAC AAAGCCACCT AAGCTGGTAC TTCAGCCCAG AGACAGAAGA ACTCCAGCGG 
CGCTGGATGG CTGTTCTCGG CAGGGCGGGC CGTGGGGACA CATTCTGCCC AGGGCCCACA 
CTGTCTGAGG ACAAGGAGAT GGAGGAGACA CCAGTGGCAG CCTCAGGAGC CACTGCTGAA 
CCTCCTGAAG CCTCCCAGAC CCGAGACAAG ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgd1 ( XM_006528699.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006528762.1 Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.

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CloneID	OMu56586
Clone ID Related Accession (Same CDS sequence)	XM_006528699.3 , XM_006528699.4
Accession Version	XM_006528699.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	FYVE, RhoGEF and PH domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006528699.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGGG TGCTTCCTCC TCCTGAGCCC ATTCCTCCAC CACCATCACG CCCTCTGCCT 
GCAGACCCTA GAGTGGCCAA GGGACTCGTC CCCAGAGCTG AGGCCAGCAC TAGTTCTGCA 
GCAGTATCAT CATTGATTGA GAAGTTTGAA AGAGAGCCTG TGATTGTTGC CTCGGATAGG 
CCAGCCCCTG GCCCCTGCCC AGTTCCCCCA GAGCCAGCCA TGTTGCCACA GCCACCCCCG 
CAGCCAACAG GGTCCCAGCT CCCTGAGGGT GAAGCTTCTC GCTGCCTGTT CCTGCTGGCT 
CCTGGGCCCC GGGATGGTGA GAAGGTGCCT AACCGGGACA GCGGCATTGA CAGCATCAGC 
TCGCCATCCA ACAGTGAAGA GACCTGCTTC GTCAGTGATG ATGGGCCCCC CATCCACAGC 
CTCTGTCCTG GGCCCCCCGC CCTGGCTAGT ATGCCAGTAG CTTTGGCCGA CCCCCACCGG 
CCTGGCTCCC AGGAGGTTGA CAGTGACCTG GAAGAGGAAG AGGAAGAAGA AGAGGAGGAA 
AAGGAAAGAG AAATTCCAGT GCCCCCGATG GAGAGACAGG AGTCTGTGGA GCTGACTGTG 
CAGCAGAAGG TGTTCCATAT TGCCAATGAG CTCCTGCAAA CTGAGAAGGC CTATGTTTCC 
AGGCTCCATC TCCTGGATCA GGTATTCTGT GCCCGGCTGC TGGAAGAAGC TCGGAACCGC 
AGTTCCTTCC CCGCAGATGT TGTCCACGGC ATCTTCTCTA ACATCTGCTC CATCTATTGC 
TTCCACCAGC AGTTCCTGCT GCCTGAGCTA GAGAAGCGCA TGGAGGAATG GGACCGCTAC 
CCACGCATTG GTGACATTCT TCAGAAGTTG GCACCCTTCC TCAAGATGTA TGGCGAGTAT 
GTGAAAAACT TCGACCGGGC GGTAGAGCTG GTCAACACAT GGACAGAGCG GTCTACCCAG 
TTTAAAGTCA TCATCCATGA AGTACAGAAG GAGGAAGCCT GTGGCAACCT GACCTTGCAG 
CACCACATGC TGGAGCCCGT GCAGCGTATC CCCCGCTATG AACTTCTTCT CAAGGACTAT 
CTGTTAAAGC TGCCTCATGG CTCCCCGGAC AGCAAGGATG CCCAGAAGTC TTTGGAGCTG 
ATAGCCACAG CAGCAGAACA CTCTAATGCT GCCATCCGGA AAATGGAACG AATGCACAAG 
CTGCTGAAGG TGTATGAGCT GCTAGGGGGT GAGGAGGACA TTGTCAGTCC CACCAAAGAG 
CTCATAAAGG AAGGCCATAT CCTTAAGCTG TCAGCAAAGA ATGGGACCAC TCAAGATCGA 
TACCTCATAT TATTCAACGA CCGCCTCCTT TACTGCGTGC CCAGGCTGCG GCTCCTTGGT 
CAGAAGTTTA GCGTGCGGGC ACGCATTGAT GTAGATGGCA TGGAGCTAAA GGAGAGCTCC 
AACCTCAACA TGCCTCGGAC CTTCCTGGTG TCAGGAAAGC AGCGCTCTCT CGAACTGCAG 
GCCAGGACTG AGGAGGAGAA GAAAGACTGG GTCCAGGCCA TCAATTCCAC CCTCCTGAAG 
CATGAACAGA CCCTGGAGAC TTTCAAACTG TTGAACTCAA CAAACAGGGA TGATGAAGAT 
ACTCCCCCTA ACTCTCCAAA CGTGGATCTT GGGAAGAGGG CACCTACGCC TATCCGGGAA 
AAGGAAGTCA CCATGTGCAT GCGCTGCCAG GAGCCCTTCA ATTCCATCAC CAAACGCAGG 
CACCACTGCA AGGCCTGTGG GCATGTGGTT TGTGGGAAAT GCTCTGAGTT CCGAGCCCGA 
CTCATCTATG ACAACAATCG TTCCAACCGT GTGTGCACTG ATTGCTATGT GGCCTTGCAT 
GGAGCACCTG GGAGCAGTCC AGCCTGTAGC CAGCATACAC CCCAGCGCAG GAGGTCCATC 
CTAGAGAAAC AGGCCTCGGT CGCTGCTGAG AACAGCGTCA TCTGCAGCTT CCTGCACTAC 
ATGGAGAAGG GTGGGAAAGG ATGGCACAAG GCATGGTTTG TGGTTCCTGA GAATGAACCC 
TTGGTGCTGT ACATCTATGG AGCCCCTCAG GATGTGAAAG CCCAGCGCAG CCTGCCCCTC 
ATTGGCTTTG AGGTGGGGCC TCCTGAGGCA GGAGAGCGGC CAGACAGGAG GCATGTCTTC 
AAGATCACAC AAAGCCACCT AAGCTGGTAC TTCAGCCCAG AGACAGAAGA ACTCCAGCGG 
CGCTGGATGG CTGTTCTCGG CAGGGCGGGC CGTGGGGACA CATTCTGCCC AGGGCCCACA 
CTGTCTGAGG ACAAGGAGAT GGAGGAGACA CCAGTGGCAG CCTCAGGAGC CACTGCTGAA 
CCTCCTGAAG CCTCCCAGAC CCGAGACAAG ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006528762.1
CDS	261..2636
Translation	MPRVLPPPEPIPPPPSRPLPADPRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPEPAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDLEEEEEEEEEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAASGATAEPPEASQTRDKT

Target ORF information:

RefSeq Version	XM_006528699.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FYVE, RhoGEF and PH domain containing 1 (Fgd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006528699.4

ORF Insert Sequence:

ATGCCCCGGG TGCTTCCTCC TCCTGAGCCC ATTCCTCCAC CACCATCACG CCCTCTGCCT 
GCAGACCCTA GAGTGGCCAA GGGACTCGTC CCCAGAGCTG AGGCCAGCAC TAGTTCTGCA 
GCAGTATCAT CATTGATTGA GAAGTTTGAA AGAGAGCCTG TGATTGTTGC CTCGGATAGG 
CCAGCCCCTG GCCCCTGCCC AGTTCCCCCA GAGCCAGCCA TGTTGCCACA GCCACCCCCG 
CAGCCAACAG GGTCCCAGCT CCCTGAGGGT GAAGCTTCTC GCTGCCTGTT CCTGCTGGCT 
CCTGGGCCCC GGGATGGTGA GAAGGTGCCT AACCGGGACA GCGGCATTGA CAGCATCAGC 
TCGCCATCCA ACAGTGAAGA GACCTGCTTC GTCAGTGATG ATGGGCCCCC CATCCACAGC 
CTCTGTCCTG GGCCCCCCGC CCTGGCTAGT ATGCCAGTAG CTTTGGCCGA CCCCCACCGG 
CCTGGCTCCC AGGAGGTTGA CAGTGACCTG GAAGAGGAAG AGGAAGAAGA AGAGGAGGAA 
AAGGAAAGAG AAATTCCAGT GCCCCCGATG GAGAGACAGG AGTCTGTGGA GCTGACTGTG 
CAGCAGAAGG TGTTCCATAT TGCCAATGAG CTCCTGCAAA CTGAGAAGGC CTATGTTTCC 
AGGCTCCATC TCCTGGATCA GGTATTCTGT GCCCGGCTGC TGGAAGAAGC TCGGAACCGC 
AGTTCCTTCC CCGCAGATGT TGTCCACGGC ATCTTCTCTA ACATCTGCTC CATCTATTGC 
TTCCACCAGC AGTTCCTGCT GCCTGAGCTA GAGAAGCGCA TGGAGGAATG GGACCGCTAC 
CCACGCATTG GTGACATTCT TCAGAAGTTG GCACCCTTCC TCAAGATGTA TGGCGAGTAT 
GTGAAAAACT TCGACCGGGC GGTAGAGCTG GTCAACACAT GGACAGAGCG GTCTACCCAG 
TTTAAAGTCA TCATCCATGA AGTACAGAAG GAGGAAGCCT GTGGCAACCT GACCTTGCAG 
CACCACATGC TGGAGCCCGT GCAGCGTATC CCCCGCTATG AACTTCTTCT CAAGGACTAT 
CTGTTAAAGC TGCCTCATGG CTCCCCGGAC AGCAAGGATG CCCAGAAGTC TTTGGAGCTG 
ATAGCCACAG CAGCAGAACA CTCTAATGCT GCCATCCGGA AAATGGAACG AATGCACAAG 
CTGCTGAAGG TGTATGAGCT GCTAGGGGGT GAGGAGGACA TTGTCAGTCC CACCAAAGAG 
CTCATAAAGG AAGGCCATAT CCTTAAGCTG TCAGCAAAGA ATGGGACCAC TCAAGATCGA 
TACCTCATAT TATTCAACGA CCGCCTCCTT TACTGCGTGC CCAGGCTGCG GCTCCTTGGT 
CAGAAGTTTA GCGTGCGGGC ACGCATTGAT GTAGATGGCA TGGAGCTAAA GGAGAGCTCC 
AACCTCAACA TGCCTCGGAC CTTCCTGGTG TCAGGAAAGC AGCGCTCTCT CGAACTGCAG 
GCCAGGACTG AGGAGGAGAA GAAAGACTGG GTCCAGGCCA TCAATTCCAC CCTCCTGAAG 
CATGAACAGA CCCTGGAGAC TTTCAAACTG TTGAACTCAA CAAACAGGGA TGATGAAGAT 
ACTCCCCCTA ACTCTCCAAA CGTGGATCTT GGGAAGAGGG CACCTACGCC TATCCGGGAA 
AAGGAAGTCA CCATGTGCAT GCGCTGCCAG GAGCCCTTCA ATTCCATCAC CAAACGCAGG 
CACCACTGCA AGGCCTGTGG GCATGTGGTT TGTGGGAAAT GCTCTGAGTT CCGAGCCCGA 
CTCATCTATG ACAACAATCG TTCCAACCGT GTGTGCACTG ATTGCTATGT GGCCTTGCAT 
GGAGCACCTG GGAGCAGTCC AGCCTGTAGC CAGCATACAC CCCAGCGCAG GAGGTCCATC 
CTAGAGAAAC AGGCCTCGGT CGCTGCTGAG AACAGCGTCA TCTGCAGCTT CCTGCACTAC 
ATGGAGAAGG GTGGGAAAGG ATGGCACAAG GCATGGTTTG TGGTTCCTGA GAATGAACCC 
TTGGTGCTGT ACATCTATGG AGCCCCTCAG GATGTGAAAG CCCAGCGCAG CCTGCCCCTC 
ATTGGCTTTG AGGTGGGGCC TCCTGAGGCA GGAGAGCGGC CAGACAGGAG GCATGTCTTC 
AAGATCACAC AAAGCCACCT AAGCTGGTAC TTCAGCCCAG AGACAGAAGA ACTCCAGCGG 
CGCTGGATGG CTGTTCTCGG CAGGGCGGGC CGTGGGGACA CATTCTGCCC AGGGCCCACA 
CTGTCTGAGG ACAAGGAGAT GGAGGAGACA CCAGTGGCAG CCTCAGGAGC CACTGCTGAA 
CCTCCTGAAG CCTCCCAGAC CCGAGACAAG ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.
The Journal of clinical investigation121(11)4383-92(2011 Nov)
Zou W,Greenblatt MB,Shim JH,Kant S,Zhai B,Lotinun S,Brady N,Hu DZ,Gygi SP,Baron R,Davis RJ,Jones D,Glimcher LH

Faciogenital dysplasia protein (FGD1) regulates export of cargo proteins from the golgi complex via Cdc42 activation.
Molecular biology of the cell20(9)2413-27(2009 May)
Egorov MV,Capestrano M,Vorontsova OA,Di Pentima A,Egorova AV,Mariggi? S,Ayala MI,Tet? S,Gorski JL,Luini A,Buccione R,Polishchuk RS

Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.
Genes to cells : devoted to molecular & cellular mechanisms13(4)329-42(2008 Apr)
Hayakawa M,Matsushima M,Hagiwara H,Oshima T,Fujino T,Ando K,Kikugawa K,Tanaka H,Miyazawa K,Kitagawa M

Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.
Molecular and cellular biology26(23)8964-75(2006 Dec)
Kostenko EV,Olabisi OO,Sahay S,Rodriguez PL,Whitehead IP

Effect of Fgd1 on cortactin in Arp2/3 complex-mediated actin assembly.
Biochemistry43(9)2422-7(2004 Mar)
Kim K,Hou P,Gorski JL,Cooper JA

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Fgd1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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