Fabp3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fabp3
Entrez Gene ID	14077
Full Name	fatty acid binding protein 3, muscle and heart
Synonyms	Fabph-1,Fabph-4,Fabph1,Fabph4,H-FABP,Mdgi
General protein information	Preferred Names fatty acid binding protein 3, muscle and heart Names fatty acid-binding protein, heart fatty acid binding protein heart 1 fatty acid binding protein heart 4 fatty acid-binding protein 3 heart-type fatty acid-binding protein mammary-derived growth inhibitor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D2.2\|4 63.43 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010174.1	NP_034304.1	fatty acid-binding protein, heart
NM_010174.2	NP_034304.1	fatty acid-binding protein, heart

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	fabp3	NP_694493.1
Xenopus tropicalis (tropical clawed frog)	fabp3	NP_001015823.1
Canis lupus familiaris (dog)	FABP3	XP_005617722.1
Mus musculus (house mouse)	Fabp3	NP_034304.1
Gallus gallus (chicken)	FABP3	NP_001026060.1
Bos taurus (cattle)	FABP3	NP_776738.1
Homo sapiens (human)	FABP3	NP_004093.1
Pan troglodytes (chimpanzee)	FABP3	XP_003307987.1
Rattus norvegicus (Norway rat)	Fabp3	NP_077076.1

Gene Ontology
Bibliography

Related articles in PubMed

Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.
Bai Z, Chai XR, Yoon MJ, Kim HJ, Lo KA, Zhang ZC, Xu D, Siang DTC, Walet ACE, Xu SH, Chia SY, Chen P, Yang H, Ghosh S, Sun L
PLoS biology15(8)e2002176(2017 Aug)

Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues.
Singh R, Braga M, Reddy ST, Lee SJ, Parveen M, Grijalva V, Vergnes L, Pervin S
Endocrinology158(5)1217-1230(2017 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results confirmed the altered expression of HFABP, a key fatty acid transport protein, and of enolase and PGK1, the key enzymes in the glycolytic process
Title: Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level.

Increased placental FABP3 promotes fatty acid transport and contributes to excess lipid accumulation in the fetal liver in model of obesity in pregnancy.
Title: Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy.

The frameshift and missense mutations in FABP3, FABP5, and FABP7 genes have been identified in schizophrenia and autism spectrum disorder in humans and in mouse behavioral studies.
Title: Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.

The FABP3 is induced in the mesangial cells and likely a mediator to induce MCP-1 in the diabetic nephropathy.
Title: Fatty acid binding protein 3 as a potential mediator for diabetic nephropathy in eNOS deficient mouse.

Collectively FABP3 regulates n-3 (omega-3) and n-6 (omega-6) polyunsaturated FA transport in trophoblasts and plays a pivotal role in fetal development.
Title: Fatty Acid Binding Protein 3 Is Involved in n-3 and n-6 PUFA transport in mouse trophoblasts.

The following Fabp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fabp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05674	NM_010174.2 Latest version!	Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu05674	NM_010174.1	Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fabp3 ( NM_010174.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034304.1 Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.

Price & Availability↑

CloneID	OMu05674
Clone ID Related Accession (Same CDS sequence)	NM_010174.1 , NM_010174.2
Accession Version	NM_010174.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Mus musculus(house mouse)
Product	fatty acid-binding protein, heart
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U02883.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U02883.1, BC002082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG CCTTTGTCGG TACCTGGAAG CTAGTGGACA GCAAGAATTT TGATGACTAC 
ATGAAGTCAC TCGGTGTGGG CTTTGCCACC AGGCAGGTGG CTAGCATGAC CAAGCCTACT 
ACCATCATCG AGAAGAACGG GGATACTATC ACCATAAAGA CACAAAGTAC CTTCAAGAAC 
ACAGAGATCA ACTTTCAGCT GGGAATAGAG TTCGACGAGG TGACAGCAGA TGACCGGAAG 
GTCAAGTCAC TGGTGACGCT GGACGGAGGC AAACTCATCC ATGTGCAGAA GTGGAACGGG 
CAGGAGACAA CACTAACTAG GGAGCTAGTT GACGGGAAAC TCATCCTGAC TCTCACTCAT 
GGCAGTGTGG TGAGCACTCG GACTTATGAG AAGGAGGCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034304.1
CDS	1..402
Translation	MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTQSTFKNTEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQETTLTRELVDGKLILTLTHGSVVSTRTYEKEA

Target ORF information:

RefSeq Version	NM_010174.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010174.1

ORF Insert Sequence:

ATGGCGGACG CCTTTGTCGG TACCTGGAAG CTAGTGGACA GCAAGAATTT TGATGACTAC 
ATGAAGTCAC TCGGTGTGGG CTTTGCCACC AGGCAGGTGG CTAGCATGAC CAAGCCTACT 
ACCATCATCG AGAAGAACGG GGATACTATC ACCATAAAGA CACAAAGTAC CTTCAAGAAC 
ACAGAGATCA ACTTTCAGCT GGGAATAGAG TTCGACGAGG TGACAGCAGA TGACCGGAAG 
GTCAAGTCAC TGGTGACGCT GGACGGAGGC AAACTCATCC ATGTGCAGAA GTGGAACGGG 
CAGGAGACAA CACTAACTAG GGAGCTAGTT GACGGGAAAC TCATCCTGAC TCTCACTCAT 
GGCAGTGTGG TGAGCACTCG GACTTATGAG AAGGAGGCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fabp3 ( NM_010174.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034304.1 Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.

Price & Availability↑

CloneID	OMu05674
Clone ID Related Accession (Same CDS sequence)	NM_010174.1 , NM_010174.2
Accession Version	NM_010174.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	fatty acid-binding protein, heart
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL772297.10. On Jun 18, 2019 this sequence version replaced NM_010174.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2760120.1, SRR7345562.3095026.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG CCTTTGTCGG TACCTGGAAG CTAGTGGACA GCAAGAATTT TGATGACTAC 
ATGAAGTCAC TCGGTGTGGG CTTTGCCACC AGGCAGGTGG CTAGCATGAC CAAGCCTACT 
ACCATCATCG AGAAGAACGG GGATACTATC ACCATAAAGA CACAAAGTAC CTTCAAGAAC 
ACAGAGATCA ACTTTCAGCT GGGAATAGAG TTCGACGAGG TGACAGCAGA TGACCGGAAG 
GTCAAGTCAC TGGTGACGCT GGACGGAGGC AAACTCATCC ATGTGCAGAA GTGGAACGGG 
CAGGAGACAA CACTAACTAG GGAGCTAGTT GACGGGAAAC TCATCCTGAC TCTCACTCAT 
GGCAGTGTGG TGAGCACTCG GACTTATGAG AAGGAGGCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034304.1
CDS	41..442
Translation	MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTQSTFKNTEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQETTLTRELVDGKLILTLTHGSVVSTRTYEKEA

Target ORF information:

RefSeq Version	NM_010174.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus fatty acid binding protein 3, muscle and heart (Fabp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010174.2

ORF Insert Sequence:

ATGGCGGACG CCTTTGTCGG TACCTGGAAG CTAGTGGACA GCAAGAATTT TGATGACTAC 
ATGAAGTCAC TCGGTGTGGG CTTTGCCACC AGGCAGGTGG CTAGCATGAC CAAGCCTACT 
ACCATCATCG AGAAGAACGG GGATACTATC ACCATAAAGA CACAAAGTAC CTTCAAGAAC 
ACAGAGATCA ACTTTCAGCT GGGAATAGAG TTCGACGAGG TGACAGCAGA TGACCGGAAG 
GTCAAGTCAC TGGTGACGCT GGACGGAGGC AAACTCATCC ATGTGCAGAA GTGGAACGGG 
CAGGAGACAA CACTAACTAG GGAGCTAGTT GACGGGAAAC TCATCCTGAC TCTCACTCAT 
GGCAGTGTGG TGAGCACTCG GACTTATGAG AAGGAGGCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.
PLoS biology15(8)e2002176(2017 Aug)
Bai Z,Chai XR,Yoon MJ,Kim HJ,Lo KA,Zhang ZC,Xu D,Siang DTC,Walet ACE,Xu SH,Chia SY,Chen P,Yang H,Ghosh S,Sun L

Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues.
Endocrinology158(5)1217-1230(2017 May)
Singh R,Braga M,Reddy ST,Lee SJ,Parveen M,Grijalva V,Vergnes L,Pervin S

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Fabp3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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