GPR6 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPR6
Entrez Gene ID	140741
Full Name	G protein-coupled receptor 6
Synonyms	AI852874,Gm233
General protein information	Preferred Names G protein-coupled receptor 6 Names G-protein coupled receptor 6 sphingosine 1-phosphate receptor GPR6
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 10 Map Location: 10 B1\|10 22.08 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_199058.1	NP_951013.1	G-protein coupled receptor 6
NM_199058.2	NP_951013.1	G-protein coupled receptor 6
XM_006512533.2	XP_006512596.1	G-protein coupled receptor 6 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	GPR6	NP_005275.1
Gallus gallus (chicken)	GPR6	XP_004940367.1
Canis lupus familiaris (dog)	GPR6	XP_005627762.1
Xenopus tropicalis (tropical clawed frog)	gpr6	XP_004914614.1
	GPR6	XP_001088851.2
Pan troglodytes (chimpanzee)	GPR6	XP_003311471.1
Bos taurus (cattle)	GPR6	NP_001093777.1
Mus musculus (house mouse)	Gpr6	NP_951013.1
Rattus norvegicus (Norway rat)	Gpr6	NP_113994.1
Danio rerio (zebrafish)	LOC100538060	XP_003200829.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation.
Tischfield DJ, Saraswat DK, Furash A, Fowler SC, Fuccillo MV, Anderson SA
Neurobiology of disease103174-183(2017 Jul)

Increased susceptibility of G-protein coupled receptor 6 deficient mice to MPTP neurotoxicity.
Oeckl P, Ferger B
Neuroscience337218-223(2016 Nov)

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons.
Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z
Cell reports16(5)1431-1444(2016 08)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Gpr6 deficiency causes an interesting behavioural phenotype in the form of enhanced motor activity combined with reduced abnormal involuntary movements.
Title: G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease.

C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity
Title: C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-? neurotoxicity.

Gpr6 is the first striatopallidal neuron-specific genetic regulator of instrumental conditioning in a mammal.
Title: Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6.

identification, characterization and cloning; identified sphingosine-1-phosphate as a high-affinity ligand
Title: Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway.

The following GPR6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu43725	NM_199058.2 Latest version!	Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu43725	XM_006512533.2 Latest version!	Mus musculus G protein-coupled receptor 6 (Gpr6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu58277	NM_199058.1 Latest version!	Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$237.30 $339.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPR6 ( NM_199058.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_951013.1 Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.

Price & Availability↑

CloneID	OMu43725
Clone ID Related Accession (Same CDS sequence)	NM_199058.2 , XM_006512533.2
Accession Version	NM_199058.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	G-protein coupled receptor 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX236691.1, AK139367.1 and AW046789.1. On or before Dec 30, 2017 this sequence version replaced XM_006512533.2, NM_199058.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CX236691.1, AK139367.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTTGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_951013.1
CDS	184..1275
Translation	MNASAAALNESQVVAVAAEGAAAAATAAGAPDTGEWGPPAASAALGGGGGPNGSLELSSQLPAGPSGLLLSAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYVVPSETVSLLMVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLADRTSCSVVRPLTRSHVALLSTSFFVVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSQEDPAIYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLFCGCFQSKVPFRSRSPSEV

Target ORF information:

RefSeq Version	NM_199058.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199058.2

ORF Insert Sequence:

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTTGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPR6 ( XM_006512533.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006512596.1 Mus musculus G protein-coupled receptor 6 (Gpr6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu43725
Clone ID Related Accession (Same CDS sequence)	NM_199058.2 , XM_006512533.2
Accession Version	XM_006512533.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	G-protein coupled receptor 6 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006512533.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTTGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006512596.1
CDS	592..1683
Translation	MNASAAALNESQVVAVAAEGAAAAATAAGAPDTGEWGPPAASAALGGGGGPNGSLELSSQLPAGPSGLLLSAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYVVPSETVSLLMVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLADRTSCSVVRPLTRSHVALLSTSFFVVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSQEDPAIYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLFCGCFQSKVPFRSRSPSEV

Target ORF information:

RefSeq Version	XM_006512533.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus G protein-coupled receptor 6 (Gpr6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006512533.2

ORF Insert Sequence:

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTTGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPR6 ( NM_199058.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_951013.1 Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.

Price & Availability↑

CloneID	OMu58277
Clone ID Related Accession (Same CDS sequence)	NM_199058.1
Accession Version	NM_199058.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-25
Organism	Mus musculus(House mouse)
Product	G-protein coupled receptor 6
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY064488.1. ##Evidence-Data-START## Transcript is intronless :: AY064488.1 [ECO:0000345] ##Evidence-Data-END##

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTGGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_951013.1
CDS	1..1092
Translation	MNASAAALNESQVVAVAAEGAAAAATAAGAPDTGEWGPPAASAALGGGGGPNGSLELSSQLPAGPSGLLLSAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYVVPSETVSLLMVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLADRTSCSVVRPLTRSHVALLSTSFFVVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSQEDPAIYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLFCGCFQSKVPFRSRSPSEV

Target ORF information:

RefSeq Version	NM_199058.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus G protein-coupled receptor 6 (Gpr6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199058.1

ORF Insert Sequence:

ATGAACGCTA GCGCCGCCGC GCTCAACGAG TCCCAAGTGG TGGCAGTAGC GGCCGAGGGA 
GCGGCAGCTG CGGCTACAGC AGCAGGGGCA CCGGACACCG GCGAATGGGG ACCCCCAGCA 
GCATCCGCAG CGCTGGGAGG CGGCGGCGGA CCTAACGGGT CACTGGAGCT GTCTTCTCAG 
CTGCCAGCAG GGCCCTCGGG ACTACTGCTT TCGGCAGTGA ATCCCTGGGA TGTGCTGCTG 
TGCGTGTCGG GAACTGTGAT CGCAGGCGAA AATGCGCTGG TGGTGGCGCT CATCGCGTCC 
ACTCCCGCGC TGCGCACGCC CATGTTTGTG CTCGTGGGTA GTCTGGCCAC TGCTGACCTG 
TTGGCGGGCT GTGGCCTCAT CTTACACTTC GTGTTCCAGT ACGTGGTGCC CTCGGAGACT 
GTGAGCCTGC TCATGGTGGG CTTCCTGGTG GCGTCCTTTG CCGCCTCAGT CAGCAGCCTG 
CTTGCTATCA CAGTGGACCG TTACCTGTCT TTGTACAACG CGCTCACCTA CTACTCGCGC 
CGGACCCTGT TGGGCGTGCA CCTCTTGCTA GCAGCCACCT GGACAGTGTC CCTCGGGTTG 
GGGTTGCTGC CTGTTCTAGG CTGGAACTGC TTGGCCGACC GCACGTCCTG CAGCGTGGTG 
CGCCCCCTGA CACGCAGCCA TGTGGCGTTG CTCTCTACTT CCTTCTTCGT GGTCTTTGGC 
ATCATGCTGC ACTTGTACGT GCGCATCTGC CAGGTGGTCT GGCGCCACGC CCACCAGATC 
GCTTTGCAAC AGCATTGCCT AGCACCGCCC CACTTAGCAG CCACCAGAAA GGGAGTGGGA 
ACTTTGGCCG TGGTGCTAGG CACTTTTGGG GCCAGCTGGC TGCCCTTCGC CATCTATTGT 
GTGGTGGGTA GCCAAGAGGA CCCGGCCATC TACACTTATG CCACCCTGTT GCCTGCCACC 
TATAACTCCA TGATCAATCC CATCATCTAT GCCTTCCGCA ACCAGGAGAT CCAGCGTGCC 
TTGTGGCTCC TGTTCTGTGG CTGTTTCCAA TCCAAAGTGC CCTTCCGCTC CAGGTCCCCC 
AGTGAGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation.
Neurobiology of disease103174-183(2017 Jul)
Tischfield DJ,Saraswat DK,Furash A,Fowler SC,Fuccillo MV,Anderson SA

Increased susceptibility of G-protein coupled receptor 6 deficient mice to MPTP neurotoxicity.
Neuroscience337218-223(2016 Nov)
Oeckl P,Ferger B

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons.
Cell reports16(5)1431-1444(2016 08)
Zhang Q,Zhang Y,Wang C,Xu Z,Liang Q,An L,Li J,Liu Z,You Y,He M,Mao Y,Chen B,Xiong ZQ,Rubenstein JL,Yang Z

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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GPR6 cDNA ORF clone, Mus musculus(House mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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