Khdrbs3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Khdrbs3
Entrez Gene ID	13992
Full Name	KH domain containing, RNA binding, signal transduction associated 3
Synonyms	Etle,SLM-2,Salp,Slm2,T-STAR
General protein information	Preferred Names KH domain containing, RNA binding, signal transduction associated 3 Names KH domain-containing, RNA-binding, signal transduction-associated protein 3 RNA-binding protein Etoile etoile sam68-like mammalian protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 D3\|15 30.36 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010158.2	NP_034288.2	KH domain-containing, RNA-binding, signal transduction-associated protein 3
XM_006520410.3	XP_006520473.1	KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X1
XM_006520410.4	XP_006520473.1	KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KHDRBS3	NP_006549.1
	LOC705288	XP_001093657.2
Rattus norvegicus (Norway rat)	Khdrbs3	NP_071585.1
Bos taurus (cattle)	KHDRBS3	NP_001076981.1
Drosophila melanogaster (fruit fly)	qkr58E-1	NP_523809.2
Canis lupus familiaris (dog)	KHDRBS3	XP_848348.2
Gallus gallus (chicken)	KHDRBS3	XP_001231272.1
Danio rerio (zebrafish)	khdrbs3	XP_005172612.1
Drosophila melanogaster (fruit fly)	qkr54B	NP_001261050.1
Xenopus tropicalis (tropical clawed frog)	khdrbs3	XP_002932263.1
Pan troglodytes (chimpanzee)	KHDRBS3	XP_519974.3
Mus musculus (house mouse)	Khdrbs3	NP_034288.2

Gene Ontology
Bibliography

Related articles in PubMed

Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.
Sato Y, Suzuki S, Iijima Y, Iijima T
Biochemical and biophysical research communications493(2)1030-1036(2017 11)

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Rutledge EA, Benazet JD, McMahon AP
Development (Cambridge, England)144(17)3177-3188(2017 09)

A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior.
Ehrmann I, Gazzara MR, Pagliarini V, Dalgliesh C, Kheirollahi-Chadegani M, Xu Y, Cesari E, Danilenko M, Maclennan M, Lowdon K, Vogel T, Keskivali-Bond P, Wells S, Cater H, Fort P, Santibanez-Koref M, Middei S, Sette C, Clowry GJ, Barash Y, Cunningham MO, Elliott DJ
Cell reports17(12)3269-3280(2016 12)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Control of neuronal synapse specification by a highly dedicated alternative splicing program.
Traunm?ller L, Gomez AM, Nguyen TM, Scheiffele P
Science (New York, N.Y.)352(6288)982-6(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

(Nrxn) is a critical element in selective trans-synaptic interactions. This study evaluated the synaptogenic receptor activity of NL1/2/3 isoforms in a neuron-fibroblast co-culture system, in which the Nrxn AS4 segments are manipulated using SLM2, a selective and dominant regulator of AS4 splicing.
Title: Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.

Our data reveal a pathway of SLM2 homeostatic auto-regulation controlling brain network activity and behavior
Title: A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior.

this study found that the RNA-binding protein SLM2 is essential for functional specification of glutamatergic synapses in the mouse hippocampus.
Title: Control of neuronal synapse specification by a highly dedicated alternative splicing program.

Sam68 and T-STAR could regulate alternative splicing of some pre-mRNAs by bringing two distant UAA motifs into proximity and looping out regions of the pre-mRNA.
Title: Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.

A hierarchical, SLM2-dependent mechanism in hippocampus was identified for cell type-specific expression of neuronal splicing regulators.
Title: Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins.

The following Khdrbs3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Khdrbs3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05651	NM_010158.2 Latest version!	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu50931	XM_006520410.4 Latest version!	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu50931	XM_006520410.3	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Khdrbs3 ( NM_010158.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034288.2 Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), mRNA.

Price & Availability↑

CloneID	OMu05651
Clone ID Related Accession (Same CDS sequence)	NM_010158.2
Accession Version	NM_010158.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	KH domain-containing, RNA-binding, signal transduction-associated protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123936.4, AF079763.1, AF099092.1 and BC031507.1. On Nov 9, 2006 this sequence version replaced NM_010158.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF079763.1, AF099092.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGA AGTACCTGCC GGAGCTGATG GCGGAGAAGG ACTCTCTGGA CCCCTCCTTC 
ACGCACGCCC TGCGCTTGGT GAACCGAGAA ATAGAAAAGT TTCAAAAGGG AGAAGGCAAG 
GAGGAAGAGA AGTACATTGA CGTGGTGATA AACAAGAACA TGAAGCTGGG ACAGAAGGTG 
CTGATTCCCG TGAAGCAGTT TCCCAAGTTC AACTTTGTGG GGAAGCTTTT GGGTCCGCGT 
GGCAATTCCC TGAAGCGCTT ACAAGAAGAA ACGTTGACAA AAATGTCCAT CCTTGGCAAA 
GGTTCCATGA GAGACAAGGC AAAGGAGGAA GAGCTGAGGA AAAGTGGAGA AGCGAAGTAC 
TTTCACCTCA ATGACGACCT GCACGTGCTC ATTGAAGTGT TCGCACCCCC AGCAGAAGCA 
TATGCCCGGA TGGGGCACGC CTTGGAAGAG ATCAAGAAAT TCCTGATCCC TGACTATAAT 
GATGAAATCA GGCAAGCACA ACTCCAGGAG TTAACATATT TGAATGGAGG TTCAGAAAAT 
GCAGATGTCC CAGTGGTTCG AGGGAAATCT ACTTTGCGTA CGAGAGGTGT AACTACACCA 
GCAATAACCA GGGGAAGAGG AGGAGTCACA GCCAGGCCTG TTGCAGTTGG GGTACCACGT 
GGGACACCGA CTCCCCGAGG AGTCCTTTCC ACCCGAGGGC CAGTGAGCCG GGGAAGAGGC 
CTTCTCACTC CCAGAGCAAG AGGTGTCCCC CCAACCGGAT ACAGACCTCC CCCGCCACCC 
CCAACACAGG AGACCTATGG AGAGTATGAC TATGACGATG GGTACGGTAC TGCCTATGAT 
GAGCAGAGCT ATGACTCCTA TGACAACAGC TACAGCACCC CAGCACAAAG TGCAGCTGAT 
TACTACGATT ATGGGCATGG ACTCAGCGAG GACGCTTATG ACTCCTATGG GCAAGAGGAA 
TGGACTAACT CAAGACATAA GGCTCCTTCG GCGAGGACGG CGAAGGGCGT CTACAGAGAC 
CAGCCATATG GCAGATACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034288.2
CDS	327..1367
Translation	MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSAADYYDYGHGLSEDAYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY

Target ORF information:

RefSeq Version	NM_010158.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010158.2

ORF Insert Sequence:

ATGGAGGAGA AGTACCTGCC GGAGCTGATG GCGGAGAAGG ACTCTCTGGA CCCCTCCTTC 
ACGCACGCCC TGCGCTTGGT GAACCGAGAA ATAGAAAAGT TTCAAAAGGG AGAAGGCAAG 
GAGGAAGAGA AGTACATTGA CGTGGTGATA AACAAGAACA TGAAGCTGGG ACAGAAGGTG 
CTGATTCCCG TGAAGCAGTT TCCCAAGTTC AACTTTGTGG GGAAGCTTTT GGGTCCGCGT 
GGCAATTCCC TGAAGCGCTT ACAAGAAGAA ACGTTGACAA AAATGTCCAT CCTTGGCAAA 
GGTTCCATGA GAGACAAGGC AAAGGAGGAA GAGCTGAGGA AAAGTGGAGA AGCGAAGTAC 
TTTCACCTCA ATGACGACCT GCACGTGCTC ATTGAAGTGT TCGCACCCCC AGCAGAAGCA 
TATGCCCGGA TGGGGCACGC CTTGGAAGAG ATCAAGAAAT TCCTGATCCC TGACTATAAT 
GATGAAATCA GGCAAGCACA ACTCCAGGAG TTAACATATT TGAATGGAGG TTCAGAAAAT 
GCAGATGTCC CAGTGGTTCG AGGGAAATCT ACTTTGCGTA CGAGAGGTGT AACTACACCA 
GCAATAACCA GGGGAAGAGG AGGAGTCACA GCCAGGCCTG TTGCAGTTGG GGTACCACGT 
GGGACACCGA CTCCCCGAGG AGTCCTTTCC ACCCGAGGGC CAGTGAGCCG GGGAAGAGGC 
CTTCTCACTC CCAGAGCAAG AGGTGTCCCC CCAACCGGAT ACAGACCTCC CCCGCCACCC 
CCAACACAGG AGACCTATGG AGAGTATGAC TATGACGATG GGTACGGTAC TGCCTATGAT 
GAGCAGAGCT ATGACTCCTA TGACAACAGC TACAGCACCC CAGCACAAAG TGCAGCTGAT 
TACTACGATT ATGGGCATGG ACTCAGCGAG GACGCTTATG ACTCCTATGG GCAAGAGGAA 
TGGACTAACT CAAGACATAA GGCTCCTTCG GCGAGGACGG CGAAGGGCGT CTACAGAGAC 
CAGCCATATG GCAGATACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Khdrbs3 ( XM_006520410.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520473.1 Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu50931
Clone ID Related Accession (Same CDS sequence)	XM_006520410.3 , XM_006520410.4
Accession Version	XM_006520410.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520410.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAAA TAGAAAAGTT TCAAAAGGGA GAAGGCAAGG AGGAAGAGAA GTACATTGAC 
GTGGTGATAA ACAAGAACAT GAAGCTGGGA CAGAAGGTGC TGATTCCCGT GAAGCAGTTT 
CCCAAGTTCA ACTTTGTGGG GAAGCTTTTG GGTCCGCGTG GCAATTCCCT GAAGCGCTTA 
CAAGAAGAAA CGTTGACAAA AATGTCCATC CTTGGCAAAG GTTCCATGAG AGACAAGGCA 
AAGGAGGAAG AGCTGAGGAA AAGTGGAGAA GCGAAGTACT TTCACCTCAA TGACGACCTG 
CACGTGCTCA TTGAAGTGTT CGCACCCCCA GCAGAAGCAT ATGCCCGGAT GGGGCACGCC 
TTGGAAGAGA TCAAGAAATT CCTGATCCCT GACTATAATG ATGAAATCAG GCAAGCACAA 
CTCCAGGAGT TAACATATTT GAATGGAGGT TCAGAAAATG CAGATGTCCC AGTGGTTCGA 
GGGAAATCTA CTTTGCGTAC GAGAGGTGTA ACTACACCAG CAATAACCAG GGGAAGAGGA 
GGAGTCACAG CCAGGCCTGT TGCAGTTGGG GTACCACGTG GGACACCGAC TCCCCGAGGA 
GTCCTTTCCA CCCGAGGGCC AGTGAGCCGG GGAAGAGGCC TTCTCACTCC CAGAGCAAGA 
GGTGTCCCCC CAACCGGATA CAGACCTCCC CCGCCACCCC CAACACAGGA GACCTATGGA 
GAGTATGACT ATGACGATGG GTACGGTACT GCCTATGATG AGCAGAGCTA TGACTCCTAT 
GACAACAGCT ACAGCACCCC AGCACAAAGT GCAGCTGATT ACTACGATTA TGGGCATGGA 
CTCAGCGAGG ACGCTTATGA CTCCTATGGG CAAGAGGAAT GGACTAACTC AAGACATAAG 
GCTCCTTCGG CGAGGACGGC GAAGGGCGTC TACAGAGACC AGCCATATGG CAGATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520473.1
CDS	294..1253
Translation	MEEIEKFQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSAADYYDYGHGLSEDAYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY

Target ORF information:

RefSeq Version	XM_006520410.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520410.3

ORF Insert Sequence:

ATGGAAGAAA TAGAAAAGTT TCAAAAGGGA GAAGGCAAGG AGGAAGAGAA GTACATTGAC 
GTGGTGATAA ACAAGAACAT GAAGCTGGGA CAGAAGGTGC TGATTCCCGT GAAGCAGTTT 
CCCAAGTTCA ACTTTGTGGG GAAGCTTTTG GGTCCGCGTG GCAATTCCCT GAAGCGCTTA 
CAAGAAGAAA CGTTGACAAA AATGTCCATC CTTGGCAAAG GTTCCATGAG AGACAAGGCA 
AAGGAGGAAG AGCTGAGGAA AAGTGGAGAA GCGAAGTACT TTCACCTCAA TGACGACCTG 
CACGTGCTCA TTGAAGTGTT CGCACCCCCA GCAGAAGCAT ATGCCCGGAT GGGGCACGCC 
TTGGAAGAGA TCAAGAAATT CCTGATCCCT GACTATAATG ATGAAATCAG GCAAGCACAA 
CTCCAGGAGT TAACATATTT GAATGGAGGT TCAGAAAATG CAGATGTCCC AGTGGTTCGA 
GGGAAATCTA CTTTGCGTAC GAGAGGTGTA ACTACACCAG CAATAACCAG GGGAAGAGGA 
GGAGTCACAG CCAGGCCTGT TGCAGTTGGG GTACCACGTG GGACACCGAC TCCCCGAGGA 
GTCCTTTCCA CCCGAGGGCC AGTGAGCCGG GGAAGAGGCC TTCTCACTCC CAGAGCAAGA 
GGTGTCCCCC CAACCGGATA CAGACCTCCC CCGCCACCCC CAACACAGGA GACCTATGGA 
GAGTATGACT ATGACGATGG GTACGGTACT GCCTATGATG AGCAGAGCTA TGACTCCTAT 
GACAACAGCT ACAGCACCCC AGCACAAAGT GCAGCTGATT ACTACGATTA TGGGCATGGA 
CTCAGCGAGG ACGCTTATGA CTCCTATGGG CAAGAGGAAT GGACTAACTC AAGACATAAG 
GCTCCTTCGG CGAGGACGGC GAAGGGCGTC TACAGAGACC AGCCATATGG CAGATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Khdrbs3 ( XM_006520410.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520473.1 Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu50931
Clone ID Related Accession (Same CDS sequence)	XM_006520410.3 , XM_006520410.4
Accession Version	XM_006520410.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520410.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAAA TAGAAAAGTT TCAAAAGGGA GAAGGCAAGG AGGAAGAGAA GTACATTGAC 
GTGGTGATAA ACAAGAACAT GAAGCTGGGA CAGAAGGTGC TGATTCCCGT GAAGCAGTTT 
CCCAAGTTCA ACTTTGTGGG GAAGCTTTTG GGTCCGCGTG GCAATTCCCT GAAGCGCTTA 
CAAGAAGAAA CGTTGACAAA AATGTCCATC CTTGGCAAAG GTTCCATGAG AGACAAGGCA 
AAGGAGGAAG AGCTGAGGAA AAGTGGAGAA GCGAAGTACT TTCACCTCAA TGACGACCTG 
CACGTGCTCA TTGAAGTGTT CGCACCCCCA GCAGAAGCAT ATGCCCGGAT GGGGCACGCC 
TTGGAAGAGA TCAAGAAATT CCTGATCCCT GACTATAATG ATGAAATCAG GCAAGCACAA 
CTCCAGGAGT TAACATATTT GAATGGAGGT TCAGAAAATG CAGATGTCCC AGTGGTTCGA 
GGGAAATCTA CTTTGCGTAC GAGAGGTGTA ACTACACCAG CAATAACCAG GGGAAGAGGA 
GGAGTCACAG CCAGGCCTGT TGCAGTTGGG GTACCACGTG GGACACCGAC TCCCCGAGGA 
GTCCTTTCCA CCCGAGGGCC AGTGAGCCGG GGAAGAGGCC TTCTCACTCC CAGAGCAAGA 
GGTGTCCCCC CAACCGGATA CAGACCTCCC CCGCCACCCC CAACACAGGA GACCTATGGA 
GAGTATGACT ATGACGATGG GTACGGTACT GCCTATGATG AGCAGAGCTA TGACTCCTAT 
GACAACAGCT ACAGCACCCC AGCACAAAGT GCAGCTGATT ACTACGATTA TGGGCATGGA 
CTCAGCGAGG ACGCTTATGA CTCCTATGGG CAAGAGGAAT GGACTAACTC AAGACATAAG 
GCTCCTTCGG CGAGGACGGC GAAGGGCGTC TACAGAGACC AGCCATATGG CAGATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520473.1
CDS	485..1444
Translation	MEEIEKFQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSAADYYDYGHGLSEDAYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY

Target ORF information:

RefSeq Version	XM_006520410.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520410.4

ORF Insert Sequence:

ATGGAAGAAA TAGAAAAGTT TCAAAAGGGA GAAGGCAAGG AGGAAGAGAA GTACATTGAC 
GTGGTGATAA ACAAGAACAT GAAGCTGGGA CAGAAGGTGC TGATTCCCGT GAAGCAGTTT 
CCCAAGTTCA ACTTTGTGGG GAAGCTTTTG GGTCCGCGTG GCAATTCCCT GAAGCGCTTA 
CAAGAAGAAA CGTTGACAAA AATGTCCATC CTTGGCAAAG GTTCCATGAG AGACAAGGCA 
AAGGAGGAAG AGCTGAGGAA AAGTGGAGAA GCGAAGTACT TTCACCTCAA TGACGACCTG 
CACGTGCTCA TTGAAGTGTT CGCACCCCCA GCAGAAGCAT ATGCCCGGAT GGGGCACGCC 
TTGGAAGAGA TCAAGAAATT CCTGATCCCT GACTATAATG ATGAAATCAG GCAAGCACAA 
CTCCAGGAGT TAACATATTT GAATGGAGGT TCAGAAAATG CAGATGTCCC AGTGGTTCGA 
GGGAAATCTA CTTTGCGTAC GAGAGGTGTA ACTACACCAG CAATAACCAG GGGAAGAGGA 
GGAGTCACAG CCAGGCCTGT TGCAGTTGGG GTACCACGTG GGACACCGAC TCCCCGAGGA 
GTCCTTTCCA CCCGAGGGCC AGTGAGCCGG GGAAGAGGCC TTCTCACTCC CAGAGCAAGA 
GGTGTCCCCC CAACCGGATA CAGACCTCCC CCGCCACCCC CAACACAGGA GACCTATGGA 
GAGTATGACT ATGACGATGG GTACGGTACT GCCTATGATG AGCAGAGCTA TGACTCCTAT 
GACAACAGCT ACAGCACCCC AGCACAAAGT GCAGCTGATT ACTACGATTA TGGGCATGGA 
CTCAGCGAGG ACGCTTATGA CTCCTATGGG CAAGAGGAAT GGACTAACTC AAGACATAAG 
GCTCCTTCGG CGAGGACGGC GAAGGGCGTC TACAGAGACC AGCCATATGG CAGATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.
Biochemical and biophysical research communications493(2)1030-1036(2017 11)
Sato Y,Suzuki S,Iijima Y,Iijima T

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Development (Cambridge, England)144(17)3177-3188(2017 09)
Rutledge EA,Benazet JD,McMahon AP

A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior.
Cell reports17(12)3269-3280(2016 12)
Ehrmann I,Gazzara MR,Pagliarini V,Dalgliesh C,Kheirollahi-Chadegani M,Xu Y,Cesari E,Danilenko M,Maclennan M,Lowdon K,Vogel T,Keskivali-Bond P,Wells S,Cater H,Fort P,Santibanez-Koref M,Middei S,Sette C,Clowry GJ,Barash Y,Cunningham MO,Elliott DJ

High-throughput discovery of novel developmental phenotypes.
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Khdrbs3 cDNA ORF clone, Mus musculus(house mouse)

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