Ptprv cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptprv
Entrez Gene ID	13924
Full Name	protein tyrosine phosphatase, receptor type, V
Synonyms	Esp,OST,OST-PTP,mOST-PTP
General protein information	Preferred Names protein tyrosine phosphatase, receptor type, V Names receptor-type tyrosine-protein phosphatase V ES cell phosphatase R-PTP-V embryonic stem cell phosphatase embryonic stem cell protein-tyrosine phosphatase tyrosine phosphatase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 E4

mRNA and Protein(s)

mRNA	Protein	Name
NM_007955.3	NP_031981.3	receptor-type tyrosine-protein phosphatase V precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC100615656	XP_003308723.1
Gallus gallus (chicken)	PTPRVP	XP_004934890.1
Mus musculus (house mouse)	Ptprv	NP_031981.3
Rattus norvegicus (Norway rat)	Ptprv	NP_149090.1
Canis lupus familiaris (dog)	LOC607201	XP_005622267.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.
Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N
Developmental cell33(3)247-59(2015 May)

Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.
Cheverud JM, Lawson HA, Bouckaert K, Kossenkov AV, Showe LC, Cort L, Blankenhorn EP, Bedelbaeva K, Gourevitch D, Zhang Y, Heber-Katz E
Heredity112(5)508-18(2014 May)

Endocrine regulation of male fertility by the skeleton.
Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G
Cell144(5)796-809(2011 Mar)

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.
Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G
Cell142(2)296-308(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ptprv is a new direct p53 target and a key mediator of p53-induced cell cycle arrest. Ptprv acts to suppress tumor formation in vivo.
Title: G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv.

expression of the OST gene may be important during skeletogenesis, potentially from commitment of mesenchymal cells to the ossification of new bones; early in embryogenesis, regulation of OST expression may be independent of Runx2/Cbfa1
Title: The tyrosine phosphatase, OST-PTP, is expressed in mesenchymal progenitor cells early during skeletogenesis in the mouse.

The following Ptprv gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptprv cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21060	NM_007955.3 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, V (Ptprv), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptprv ( NM_007955.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031981.3 Mus musculus protein tyrosine phosphatase, receptor type, V (Ptprv), mRNA.

Price & Availability↑

CloneID	OMu21060
Clone ID Related Accession (Same CDS sequence)	NM_007955.3
Accession Version	NM_007955.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5118bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase V precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK156112.1. On Oct 16, 2007 this sequence version replaced NM_007955.2. Transcript Variant: This represents a protein-coding allele found in the NOD strain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK156112.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: based on alignments, homology ##RefSeq-Attributes-END##

ATGAGGCCCC CGATTCTGTT AGCTGCCCTC CTCTGGCTCC AGGACTCTTT GGCCCAGGAA 
GATGTATGCT CATCCTTGGA TGGGAGCCCA GACAGGCAGG GTGGAGGTCC ACCTCTGAGT 
GTGAACGTCA GCAGCCGCGG AAAGCCTACC AGCCTGTTTC TGAGCTGGGT AGCTGCAGAG 
CCAGGTGGAT TTGACTATGC CCTCTGCCTC AGGGCTATGA ACTTGTCGGG TTTTCCAGAA 
GGGCAACAGC TCCAAGCTCA TACCAACGAG TCCAGCTTTG AGTTCCATGG CCTGGTGCCA 
GGGAGTCGCT ACCAGCTGGA ACTGACTGTC CTAAGACCCT GTTGGCAGAA TGTCACAATT 
ACCCTCACTG CTCGAACTGC CCCTACAGTG GTCCGTGGAC TGCAACTGCA TAGCACTGGG 
AGCCCAGCCA GCCTGGAAGC CTCATGGAGC GATGCCTCTG GGGATCAAGA CAGCTATCAA 
CTTCTCCTCT ACCACCCGGA ATCCCACACT CTGGCATGTA ATGTCTCTGT GTCCCCTGAC 
ACCCTGTCTT ACAATTTTGG TGACCTCTTG CCAGGTAGTC AGTATGTCTT GGAGGTTATC 
ACCTGGGCTG GCAGTCTCCA TGCGAAGACT AGCATCCTCC AATGGACAGA GCCTGTCCCT 
CCTGATCACC TAACACTGCG TGCCTTGGGT ACCAGTAGCC TGCAAGCCTT CTGGAACAGC 
TCTGAAGGGG CCACCTGGTT TCACCTGATA CTTACAGACC TCCTAGAGGG TACCAACCTG 
ACCAAAGTGG TCAGACAAGG CATCTCAACC CACACCTTCC TTCGCCTGTC TCCGGGTACA 
CCTTACCAGC TGAAGATCTG TGCTGCTGCT GGGCCCCACC AGATTTGGGG ACCCAATGCC 
ATTGAGTGGA CCTATCCCTC TTACCCATCT GACCTGGTGC TGACCCCCTT ATGGAATGAG 
CTCTGGGCAA GCTGGAAGGC AGGGCAGGGA GCCCGGGATG GCTATGTACT GAAGTTAAGT 
GGGCCAGTGG AGAATACAAC TACTCTGGGT CCTGAGGAGT GCAACGCTGT CTTCCCAGGG 
CCCCTGCCTC CAGGACACTA CACTTTGGGG CTGAGGGTTC TAGCTGGACC TTATGATGCC 
TGGGTAGAGG GCAGTATCTG GCTGGCTGAA TCTGCTGCTC GTCCCATGGA GGTCCCTGGT 
GCCAGACTGT GGCTAGAAGG ACTGGAAGCT ACTAAGCAAC CTGGGAGACG GGCGCTGCTC 
TATTCTGTTG ATGCCCCAGG CCTCCTAGGG AACATCTCTG TGTCTTCTGG TGCCACTCAT 
GTCACCTTCT GTGGCTTGGT ACCCGGAGCG CACTACAGGG TGGACATTGC CTCATCCATG 
GGAGACATCA CTCAGAGCCT CACAGGCTAC ACAAGTCCCC TGCCACCACA GTCTCTGGAG 
ATCATCAGCC GGAACAGCCC ATCTGACCTG ACTATCGGTT GGGCTCCAGC ACCAGGGCAG 
ATGGAAGGTT ATAAGGTCAC CTGGCATCAG GATGGCAGCC AGAGGTCACC TGGCGACCTT 
GTTGACTTGG GCCCTGACAT TTCGAGCCTG ACTCTGAAAT CTCTGGTACC TGGTTCCTGC 
TACACCGTGT CAGCATGGGC CTGGTCTGGG AACCTCAGCT CTGACTCTCA GAAGATTCAC 
AGTTGCACCC GTCCCGCTCC TCCCACCAAC CTGAGCCTGG GCTTTGCCCA CCAGCCTGCA 
ACACTGAGGG CTTCCTGGTG TCACCCACCG GGTGGCAGGG ATGCCTTTCA GTTACGGCTT 
TACAGGCTGA GGCCCCTGAC ACTGGAAAGT GAGAAGATCC TATCCCAGGA GGCCCAGAAC 
TTCTCCTGGG CCCAGCTGCC TGCAGGCTAT GAATTCCAGG TACAGCTGTC TACCTTGTGG 
GGGTCGGAGG AGAGCGGCAG TGCCAACACC ACAGGCTGGA CACCCCCCTC AGCTCCTACA 
TTGGTAAATG TGACCAGTGA AGCCCCCACC CAGCTCCACG TATCCTGGGT CCACGCTGCT 
GGGGACCGGA GCAGCTACCA AGTGACCCTA TACCAGGAGA GCACTCGGAC AGCCACCAGC 
ATTGTGGGGC CCAAGGCAGA CAGCACAAGC TTTTGGGGTT TGACTCCTGG CACTAAGTAC 
AAGGTGGAAG CCATCTCCTG GGCTGGGCCC CTTTACACTG CAGCAGCCAA CGTTTCTGCT 
TGGACCTACC CACTCACACC CAATGAGCTG CTCGCCTCTA TGCAGGCAGG CAGTGCTGTG 
GTTAACCTGG CCTGGCCCAG TGGTCCCTTG GGGCAAGGGA CATGCCATGC CCAACTCTCA 
GATGCTGGAC ACCTTTCATG GGAGCAACCG CTGTCGCTAG GCCAAGACCT CCTCATGCTA 
AGGAATCTTA TACCAGGACA TACGGTTTCA TTGTCTGTGA AGTGTCGGGC AGGACCACTC 
CAGGCCTCCA CTCACCCCCT GGTGCTGTCT GTAGAGCCTG GCCCTGTGGA AGATGTGTTC 
TGTCAACCTG AGGCCACCTA CCTGTCCCTG AACTGGACGA TGCCTACTGG AGATGTGGCT 
GTCTGTCTGG TGGAGGTAGA GCAGCTGGTG CCAGGAGGGA GCGCTCATTT TGTCTTCCAG 
GTCAACACCT CGGAGGATGC ACTTCTGCTG CCCAACTTGA CGCCCACCAC TTCTTACCGC 
CTTAGCCTCA CTGTGCTGGG TGGGAATCGC CAGTGGAGCC GGGCGGTTAC CCTGGTGTGC 
ACTACTTCTG CTGAGGTTTG GCACCCCCCA GAGCTAGCTG AGGCCCCCCA GGTGGAGCTG 
GGGACAGGGA TGGGTGTGAC AGTCACACGT GGCATGTTTG GTAAAGATGA CGGGCAGATC 
CAGTGGTATG GCATAATTGC CACCATCAAC ATGACACTGG CCCAGCCTTC CCAGGAAGCC 
ATCAACCACA CATGGTATGA CCACTACTAT AGAGGACATG ACTCCTACCT GGCTCTCCTG 
TTCCCAAACC CCTTCTACCC AGAGCCTTGG GCTGTGCCAA GATCCTGGAC AGTACCTGTG 
GGTACAGAGG ACTGTGACAA CACCCAGGAG ATATGCAATG GGCATCTCAA GCCAGGCTTC 
CAGTATAGGT TCAGCATTGC AGCCTTTAGT AGGCTCAGCT CTCCAGAGAC CATCCTGGCC 
TTCTCCGCCT TCTCAGAGCC TCAGGCTAGC ATCTCTCTGG TGGCCATGCC CCTGACAGTT 
ATGATGGGGA CTGTGGTGGG CTGCATCATC ATTGTGTGTG CAGTGCTATG CTTGTTGTGC 
CGGCGGCGCC TGAAGGGACC AAGGTCAGAG AAGAATGGCT TTTCCCAGGA GTTGATGCCT 
TACAACCTGT GGCGGACCCA TCGGCCCATC CCCAGCCATA GCTTCCGGCA GAGCTATGAG 
GCCAAGAGTG CACGTGCACA CCAGGCCTTC TTCCAGGAAT TTGAGGAGCT GAAGGAGGTG 
GGCAAGGACC AGCCCAGACT AGAGGCTGAG CATCCTGCCA ACATCACCAA GAACCGGTAC 
CCACACGTGC TACCTTATGA CCACTCCAGG GTCAGGCTGA CCCAGCTATC AGGAGAGCCT 
CATTCTGACT ACATCAATGC CAACTTCATC CCAGGCTATA GCCACCCACA GGAGATCATT 
GCCACCCAGG GGCCTCTCAA AAAGACGCTC GAGGACTTCT GGCGGTTGGT GTGGGAGCAG 
CAAGTCCACG TGATCATCAT GCTAACTGTG GGCATGGAGA ATGGGCGGGT ACTGTGTGAG 
CACTACTGGC CAGTCAACTC CACGCCTGTC ACCCACGGTC ACATCACCAC CCACCTCCTG 
GCAGAGGAAT CTGAGGACGA GTGGACCAGG AGGGAATTCC AGCTGCAGCA CGGTGCAGAG 
CAAAAACAGA GGCGCGTGAA GCAGCTGCAG TTCACGACCT GGCCAGACCA CAGTGTCCCC 
GAGGCTCCCA GCTCTCTGCT CGCTTTTGTG GAACTGGTGC AGGAGGAGGT GAAGGCAACT 
CAGGGCAAGG GGCCCATCCT GGTGCATTGC AGTGCGGGTG TGGGCAGGAC AGGCACCTTT 
GTGGCTCTCT TACGGCTGTT GCGACAACTA GAGGAAGAAC AGGTGGTCGA TGTGTTCAAC 
ACTGTGTACA TACTCCGGCT GCACCGGCCC CTCATGATCC AGACCTTGAG TCAATACATC 
TTCCTGCACA GCTGCCTGCT GAACAAGATT CTGGAAGGGC CCTCTGACGC CTCAGACTCC 
GGCCCCATCC CTGTGATGAA TTTTGCACAA GCTTGTGCCA AGAGGGCAGC CAATGCCAAT 
GCCGGTTTCT TGAAGGAGTA CAGGCTCCTG AAGCAGGCCA TCAAGGATGA GACTGGCTCT 
CTGCTGCCCT CTCCTGACTA TAATCAGAAC AGCATCGCCT CCTGTCATCA TTCTCAGGAG 
CAGTTGGCCC TGGTGGAGGA GAGCCCTGCT GATAACATGC TGGCAGCCTC GCTCTTCCCT 
GGTGGGCCGT CTGGTCGCGA CCATGTGGTG CTGACTGGCT CGGCCGGACC AAAGGAACTC 
TGGGAAATGG TGTGGGAACA TGGCGCCTAT GTGCTTGTCT CCCTGGGTCT GCCTGATACC 
AAGGAGAAGC CACAAGACAT CTGGCCAATG GAGATGCAGC CTATTGTCAC AGACATGGTG 
ACAGTGCACA GAGTGGCTGA GAGCAACACA GCTGGCTGGC CCAGTACCCT CATCAGAGTT 
ATACATGGGG ACAGTGGGAC GGAAAGGCAG GTTCAATGCC TGCAGTTTCC ACACTGCGAG 
ACTGGGAGTG AGCTCCCAGC TAACACCCTA CTGACCTTCC TTGATGCTGT GGGCCAGTGC 
TGCTCCCGGG GCAATAGCAA GAAGCCAGGG ACCCTGCTCA GTCACTCCAG CAAGGTCACA 
AACCAGCTGA GCACCTTCTT GGCTATGGAA CAGCTGCTAC AGCAAGCAGG GACCGAGCGC 
ACAGTGGATG TCTTCAGTGT GGCCCTGAAG CAGACACAGG CCTGTGGCCT TAAGACCCCA 
ACGCTGGAGC AGTATATCTA CCTCTACAAC TGTCTGAACA GCGCATTGAG GAACAGGCTG 
CCCCGAGCTA GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031981.3
CDS	839..5956
Translation	MRPPILLAALLWLQDSLAQEDVCSSLDGSPDRQGGGPPLSVNVSSRGKPTSLFLSWVAAEPGGFDYALCLRAMNLSGFPEGQQLQAHTNESSFEFHGLVPGSRYQLELTVLRPCWQNVTITLTARTAPTVVRGLQLHSTGSPASLEASWSDASGDQDSYQLLLYHPESHTLACNVSVSPDTLSYNFGDLLPGSQYVLEVITWAGSLHAKTSILQWTEPVPPDHLTLRALGTSSLQAFWNSSEGATWFHLILTDLLEGTNLTKVVRQGISTHTFLRLSPGTPYQLKICAAAGPHQIWGPNAIEWTYPSYPSDLVLTPLWNELWASWKAGQGARDGYVLKLSGPVENTTTLGPEECNAVFPGPLPPGHYTLGLRVLAGPYDAWVEGSIWLAESAARPMEVPGARLWLEGLEATKQPGRRALLYSVDAPGLLGNISVSSGATHVTFCGLVPGAHYRVDIASSMGDITQSLTGYTSPLPPQSLEIISRNSPSDLTIGWAPAPGQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLTLKSLVPGSCYTVSAWAWSGNLSSDSQKIHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGRDAFQLRLYRLRPLTLESEKILSQEAQNFSWAQLPAGYEFQVQLSTLWGSEESGSANTTGWTPPSAPTLVNVTSEAPTQLHVSWVHAAGDRSSYQVTLYQESTRTATSIVGPKADSTSFWGLTPGTKYKVEAISWAGPLYTAAANVSAWTYPLTPNELLASMQAGSAVVNLAWPSGPLGQGTCHAQLSDAGHLSWEQPLSLGQDLLMLRNLIPGHTVSLSVKCRAGPLQASTHPLVLSVEPGPVEDVFCQPEATYLSLNWTMPTGDVAVCLVEVEQLVPGGSAHFVFQVNTSEDALLLPNLTPTTSYRLSLTVLGGNRQWSRAVTLVCTTSAEVWHPPELAEAPQVELGTGMGVTVTRGMFGKDDGQIQWYGIIATINMTLAQPSQEAINHTWYDHYYRGHDSYLALLFPNPFYPEPWAVPRSWTVPVGTEDCDNTQEICNGHLKPGFQYRFSIAAFSRLSSPETILAFSAFSEPQASISLVAMPLTVMMGTVVGCIIIVCAVLCLLCRRRLKGPRSEKNGFSQELMPYNLWRTHRPIPSHSFRQSYEAKSARAHQAFFQEFEELKEVGKDQPRLEAEHPANITKNRYPHVLPYDHSRVRLTQLSGEPHSDYINANFIPGYSHPQEIIATQGPLKKTLEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHYWPVNSTPVTHGHITTHLLAEESEDEWTRREFQLQHGAEQKQRRVKQLQFTTWPDHSVPEAPSSLLAFVELVQEEVKATQGKGPILVHCSAGVGRTGTFVALLRLLRQLEEEQVVDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPSDASDSGPIPVMNFAQACAKRAANANAGFLKEYRLLKQAIKDETGSLLPSPDYNQNSIASCHHSQEQLALVEESPADNMLAASLFPGGPSGRDHVVLTGSAGPKELWEMVWEHGAYVLVSLGLPDTKEKPQDIWPMEMQPIVTDMVTVHRVAESNTAGWPSTLIRVIHGDSGTERQVQCLQFPHCETGSELPANTLLTFLDAVGQCCSRGNSKKPGTLLSHSSKVTNQLSTFLAMEQLLQQAGTERTVDVFSVALKQTQACGLKTPTLEQYIYLYNCLNSALRNRLPRARK

Target ORF information:

RefSeq Version	NM_007955.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, V (Ptprv), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007955.3

ORF Insert Sequence:

ATGAGGCCCC CGATTCTGTT AGCTGCCCTC CTCTGGCTCC AGGACTCTTT GGCCCAGGAA 
GATGTATGCT CATCCTTGGA TGGGAGCCCA GACAGGCAGG GTGGAGGTCC ACCTCTGAGT 
GTGAACGTCA GCAGCCGCGG AAAGCCTACC AGCCTGTTTC TGAGCTGGGT AGCTGCAGAG 
CCAGGTGGAT TTGACTATGC CCTCTGCCTC AGGGCTATGA ACTTGTCGGG TTTTCCAGAA 
GGGCAACAGC TCCAAGCTCA TACCAACGAG TCCAGCTTTG AGTTCCATGG CCTGGTGCCA 
GGGAGTCGCT ACCAGCTGGA ACTGACTGTC CTAAGACCCT GTTGGCAGAA TGTCACAATT 
ACCCTCACTG CTCGAACTGC CCCTACAGTG GTCCGTGGAC TGCAACTGCA TAGCACTGGG 
AGCCCAGCCA GCCTGGAAGC CTCATGGAGC GATGCCTCTG GGGATCAAGA CAGCTATCAA 
CTTCTCCTCT ACCACCCGGA ATCCCACACT CTGGCATGTA ATGTCTCTGT GTCCCCTGAC 
ACCCTGTCTT ACAATTTTGG TGACCTCTTG CCAGGTAGTC AGTATGTCTT GGAGGTTATC 
ACCTGGGCTG GCAGTCTCCA TGCGAAGACT AGCATCCTCC AATGGACAGA GCCTGTCCCT 
CCTGATCACC TAACACTGCG TGCCTTGGGT ACCAGTAGCC TGCAAGCCTT CTGGAACAGC 
TCTGAAGGGG CCACCTGGTT TCACCTGATA CTTACAGACC TCCTAGAGGG TACCAACCTG 
ACCAAAGTGG TCAGACAAGG CATCTCAACC CACACCTTCC TTCGCCTGTC TCCGGGTACA 
CCTTACCAGC TGAAGATCTG TGCTGCTGCT GGGCCCCACC AGATTTGGGG ACCCAATGCC 
ATTGAGTGGA CCTATCCCTC TTACCCATCT GACCTGGTGC TGACCCCCTT ATGGAATGAG 
CTCTGGGCAA GCTGGAAGGC AGGGCAGGGA GCCCGGGATG GCTATGTACT GAAGTTAAGT 
GGGCCAGTGG AGAATACAAC TACTCTGGGT CCTGAGGAGT GCAACGCTGT CTTCCCAGGG 
CCCCTGCCTC CAGGACACTA CACTTTGGGG CTGAGGGTTC TAGCTGGACC TTATGATGCC 
TGGGTAGAGG GCAGTATCTG GCTGGCTGAA TCTGCTGCTC GTCCCATGGA GGTCCCTGGT 
GCCAGACTGT GGCTAGAAGG ACTGGAAGCT ACTAAGCAAC CTGGGAGACG GGCGCTGCTC 
TATTCTGTTG ATGCCCCAGG CCTCCTAGGG AACATCTCTG TGTCTTCTGG TGCCACTCAT 
GTCACCTTCT GTGGCTTGGT ACCCGGAGCG CACTACAGGG TGGACATTGC CTCATCCATG 
GGAGACATCA CTCAGAGCCT CACAGGCTAC ACAAGTCCCC TGCCACCACA GTCTCTGGAG 
ATCATCAGCC GGAACAGCCC ATCTGACCTG ACTATCGGTT GGGCTCCAGC ACCAGGGCAG 
ATGGAAGGTT ATAAGGTCAC CTGGCATCAG GATGGCAGCC AGAGGTCACC TGGCGACCTT 
GTTGACTTGG GCCCTGACAT TTCGAGCCTG ACTCTGAAAT CTCTGGTACC TGGTTCCTGC 
TACACCGTGT CAGCATGGGC CTGGTCTGGG AACCTCAGCT CTGACTCTCA GAAGATTCAC 
AGTTGCACCC GTCCCGCTCC TCCCACCAAC CTGAGCCTGG GCTTTGCCCA CCAGCCTGCA 
ACACTGAGGG CTTCCTGGTG TCACCCACCG GGTGGCAGGG ATGCCTTTCA GTTACGGCTT 
TACAGGCTGA GGCCCCTGAC ACTGGAAAGT GAGAAGATCC TATCCCAGGA GGCCCAGAAC 
TTCTCCTGGG CCCAGCTGCC TGCAGGCTAT GAATTCCAGG TACAGCTGTC TACCTTGTGG 
GGGTCGGAGG AGAGCGGCAG TGCCAACACC ACAGGCTGGA CACCCCCCTC AGCTCCTACA 
TTGGTAAATG TGACCAGTGA AGCCCCCACC CAGCTCCACG TATCCTGGGT CCACGCTGCT 
GGGGACCGGA GCAGCTACCA AGTGACCCTA TACCAGGAGA GCACTCGGAC AGCCACCAGC 
ATTGTGGGGC CCAAGGCAGA CAGCACAAGC TTTTGGGGTT TGACTCCTGG CACTAAGTAC 
AAGGTGGAAG CCATCTCCTG GGCTGGGCCC CTTTACACTG CAGCAGCCAA CGTTTCTGCT 
TGGACCTACC CACTCACACC CAATGAGCTG CTCGCCTCTA TGCAGGCAGG CAGTGCTGTG 
GTTAACCTGG CCTGGCCCAG TGGTCCCTTG GGGCAAGGGA CATGCCATGC CCAACTCTCA 
GATGCTGGAC ACCTTTCATG GGAGCAACCG CTGTCGCTAG GCCAAGACCT CCTCATGCTA 
AGGAATCTTA TACCAGGACA TACGGTTTCA TTGTCTGTGA AGTGTCGGGC AGGACCACTC 
CAGGCCTCCA CTCACCCCCT GGTGCTGTCT GTAGAGCCTG GCCCTGTGGA AGATGTGTTC 
TGTCAACCTG AGGCCACCTA CCTGTCCCTG AACTGGACGA TGCCTACTGG AGATGTGGCT 
GTCTGTCTGG TGGAGGTAGA GCAGCTGGTG CCAGGAGGGA GCGCTCATTT TGTCTTCCAG 
GTCAACACCT CGGAGGATGC ACTTCTGCTG CCCAACTTGA CGCCCACCAC TTCTTACCGC 
CTTAGCCTCA CTGTGCTGGG TGGGAATCGC CAGTGGAGCC GGGCGGTTAC CCTGGTGTGC 
ACTACTTCTG CTGAGGTTTG GCACCCCCCA GAGCTAGCTG AGGCCCCCCA GGTGGAGCTG 
GGGACAGGGA TGGGTGTGAC AGTCACACGT GGCATGTTTG GTAAAGATGA CGGGCAGATC 
CAGTGGTATG GCATAATTGC CACCATCAAC ATGACACTGG CCCAGCCTTC CCAGGAAGCC 
ATCAACCACA CATGGTATGA CCACTACTAT AGAGGACATG ACTCCTACCT GGCTCTCCTG 
TTCCCAAACC CCTTCTACCC AGAGCCTTGG GCTGTGCCAA GATCCTGGAC AGTACCTGTG 
GGTACAGAGG ACTGTGACAA CACCCAGGAG ATATGCAATG GGCATCTCAA GCCAGGCTTC 
CAGTATAGGT TCAGCATTGC AGCCTTTAGT AGGCTCAGCT CTCCAGAGAC CATCCTGGCC 
TTCTCCGCCT TCTCAGAGCC TCAGGCTAGC ATCTCTCTGG TGGCCATGCC CCTGACAGTT 
ATGATGGGGA CTGTGGTGGG CTGCATCATC ATTGTGTGTG CAGTGCTATG CTTGTTGTGC 
CGGCGGCGCC TGAAGGGACC AAGGTCAGAG AAGAATGGCT TTTCCCAGGA GTTGATGCCT 
TACAACCTGT GGCGGACCCA TCGGCCCATC CCCAGCCATA GCTTCCGGCA GAGCTATGAG 
GCCAAGAGTG CACGTGCACA CCAGGCCTTC TTCCAGGAAT TTGAGGAGCT GAAGGAGGTG 
GGCAAGGACC AGCCCAGACT AGAGGCTGAG CATCCTGCCA ACATCACCAA GAACCGGTAC 
CCACACGTGC TACCTTATGA CCACTCCAGG GTCAGGCTGA CCCAGCTATC AGGAGAGCCT 
CATTCTGACT ACATCAATGC CAACTTCATC CCAGGCTATA GCCACCCACA GGAGATCATT 
GCCACCCAGG GGCCTCTCAA AAAGACGCTC GAGGACTTCT GGCGGTTGGT GTGGGAGCAG 
CAAGTCCACG TGATCATCAT GCTAACTGTG GGCATGGAGA ATGGGCGGGT ACTGTGTGAG 
CACTACTGGC CAGTCAACTC CACGCCTGTC ACCCACGGTC ACATCACCAC CCACCTCCTG 
GCAGAGGAAT CTGAGGACGA GTGGACCAGG AGGGAATTCC AGCTGCAGCA CGGTGCAGAG 
CAAAAACAGA GGCGCGTGAA GCAGCTGCAG TTCACGACCT GGCCAGACCA CAGTGTCCCC 
GAGGCTCCCA GCTCTCTGCT CGCTTTTGTG GAACTGGTGC AGGAGGAGGT GAAGGCAACT 
CAGGGCAAGG GGCCCATCCT GGTGCATTGC AGTGCGGGTG TGGGCAGGAC AGGCACCTTT 
GTGGCTCTCT TACGGCTGTT GCGACAACTA GAGGAAGAAC AGGTGGTCGA TGTGTTCAAC 
ACTGTGTACA TACTCCGGCT GCACCGGCCC CTCATGATCC AGACCTTGAG TCAATACATC 
TTCCTGCACA GCTGCCTGCT GAACAAGATT CTGGAAGGGC CCTCTGACGC CTCAGACTCC 
GGCCCCATCC CTGTGATGAA TTTTGCACAA GCTTGTGCCA AGAGGGCAGC CAATGCCAAT 
GCCGGTTTCT TGAAGGAGTA CAGGCTCCTG AAGCAGGCCA TCAAGGATGA GACTGGCTCT 
CTGCTGCCCT CTCCTGACTA TAATCAGAAC AGCATCGCCT CCTGTCATCA TTCTCAGGAG 
CAGTTGGCCC TGGTGGAGGA GAGCCCTGCT GATAACATGC TGGCAGCCTC GCTCTTCCCT 
GGTGGGCCGT CTGGTCGCGA CCATGTGGTG CTGACTGGCT CGGCCGGACC AAAGGAACTC 
TGGGAAATGG TGTGGGAACA TGGCGCCTAT GTGCTTGTCT CCCTGGGTCT GCCTGATACC 
AAGGAGAAGC CACAAGACAT CTGGCCAATG GAGATGCAGC CTATTGTCAC AGACATGGTG 
ACAGTGCACA GAGTGGCTGA GAGCAACACA GCTGGCTGGC CCAGTACCCT CATCAGAGTT 
ATACATGGGG ACAGTGGGAC GGAAAGGCAG GTTCAATGCC TGCAGTTTCC ACACTGCGAG 
ACTGGGAGTG AGCTCCCAGC TAACACCCTA CTGACCTTCC TTGATGCTGT GGGCCAGTGC 
TGCTCCCGGG GCAATAGCAA GAAGCCAGGG ACCCTGCTCA GTCACTCCAG CAAGGTCACA 
AACCAGCTGA GCACCTTCTT GGCTATGGAA CAGCTGCTAC AGCAAGCAGG GACCGAGCGC 
ACAGTGGATG TCTTCAGTGT GGCCCTGAAG CAGACACAGG CCTGTGGCCT TAAGACCCCA 
ACGCTGGAGC AGTATATCTA CCTCTACAAC TGTCTGAACA GCGCATTGAG GAACAGGCTG 
CCCCGAGCTA GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.
Developmental cell33(3)247-59(2015 May)
Kidoya H,Naito H,Muramatsu F,Yamakawa D,Jia W,Ikawa M,Sonobe T,Tsuchimochi H,Shirai M,Adams RH,Fukamizu A,Takakura N

Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.
Heredity112(5)508-18(2014 May)
Cheverud JM,Lawson HA,Bouckaert K,Kossenkov AV,Showe LC,Cort L,Blankenhorn EP,Bedelbaeva K,Gourevitch D,Zhang Y,Heber-Katz E

Endocrine regulation of male fertility by the skeleton.
Cell144(5)796-809(2011 Mar)
Oury F,Sumara G,Sumara O,Ferron M,Chang H,Smith CE,Hermo L,Suarez S,Roth BL,Ducy P,Karsenty G

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.
Cell142(2)296-308(2010 Jul)
Ferron M,Wei J,Yoshizawa T,Del Fattore A,DePinho RA,Teti A,Ducy P,Karsenty G

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Ptprv cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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