Egr4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Egr4
Entrez Gene ID	13656
Full Name	early growth response 4
Synonyms	NGF1-C,NGFI-C,NGFIC,pAT133
General protein information	Preferred Names early growth response 4 Names early growth response protein 4 EGR-4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 C3\|6 37.48 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_020596.2	NP_065621.1	early growth response protein 4
NM_020596.3	NP_065621.1	early growth response protein 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	EGR4	NP_001956.3
Mus musculus (house mouse)	Egr4	NP_065621.1
Rattus norvegicus (Norway rat)	Egr4	NP_062010.1
Bos taurus (cattle)	EGR4	NP_001035587.1
Gallus gallus (chicken)	EGR4	XP_420888.1
Pan troglodytes (chimpanzee)	EGR4	XP_001142546.1
	LOC714407	XP_001104148.2
Canis lupus familiaris (dog)	EGR4	XP_540228.3
Xenopus tropicalis (tropical clawed frog)	egr4	XP_004911346.1

Gene Ontology
Bibliography

Related articles in PubMed

Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons.
Ludwig A, Uvarov P, Pellegrino C, Thomas-Crusells J, Schuchmann S, Saarma M, Airaksinen MS, Rivera C
Neural plasticity20111-8(2011)

Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription.
Ludwig A, Uvarov P, Soni S, Thomas-Crusells J, Airaksinen MS, Rivera C
The Journal of neuroscience : the official journal of the Society for Neuroscience31(2)644-9(2011 Jan)

EGR4 displays both a cell- and intracellular-specific localization pattern in the developing murine testis.
Hogarth CA, Mitchell D, Small C, Griswold M
Developmental dynamics : an official publication of the American Association of Anatomists239(11)3106-14(2010 Nov)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD
The Journal of neuroscience : the official journal of the Society for Neuroscience29(36)11399-408(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Egr4 expression is triggered by trophic factor neurturin to upregulate K-Cl cotransporter KCC2 in immature neurons.
Title: Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons.

Egr4 is an important component in the mechanism of BDNF-dependent KCC2 gene regulation via the ERK1/2 pathway in immature neurons.
Title: Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription.

Data suggest that Egr4 may regulate spermatogenesis at multiple steps, with roles in the dividing Sertoli cells, peritubular myoid cells, and the meiotic and elongating haploid germ cell populations.
Title: EGR4 displays both a cell- and intracellular-specific localization pattern in the developing murine testis.

An important role for Egr4 is indicated in the developmental upregulation of potassium-chloride cotransporter (KCC2) gene expression.
Title: Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4.

The following Egr4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Egr4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu12032	NM_020596.3 Latest version!	Mus musculus early growth response 4 (Egr4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OMu12032	NM_020596.2	Mus musculus early growth response 4 (Egr4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Egr4 ( NM_020596.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_065621.1 Mus musculus early growth response 4 (Egr4), mRNA.

Price & Availability↑

CloneID	OMu12032
Clone ID Related Accession (Same CDS sequence)	NM_020596.2 , NM_020596.3
Accession Version	NM_020596.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Mus musculus(house mouse)
Product	early growth response protein 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC104743.28. On Nov 17, 2006 this sequence version replaced NM_020596.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK141637.1, CJ064102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGCTCCACC TGAGCGACTT CTCCGGCTCC GACGCGCTTC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACG CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTTTGAGCA GCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCCTGGCA CCCTTCCCCG GTCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGCCCCGATG CCTTGCTGCC GGACCTCTAC 
TCCCCAGATC TGAGTTCGGC CGCCTTTCCG GAGGCGTTTT GGGAGGCAGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCAGGG 
CTGCGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCAGCCTT CAAAGGGCCC 
TATGCCCCCT GGGAGCTGCT GTCGGCCGGG GTCCCGGGGA ACTGTGGGTC GCAGGGGAGC 
TTCCAGACCA CCCCGGAGGC CCGCTTCTCT GCAGTAGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGC CCGGCCGCCA GACTCTACCA GGCAGGGGCC 
TACGACACCT TCTCGTTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCCGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GCCCCTCCGG CGCAGCTGTC CCCTCTAGGC CTGCGCGGTG CCGCCACGGC GGACTTCTCC 
AAACCCCTGG TGGCCGATCT CCCGGGGGGC AGCGGCGTGG CCGCGCCCTC ATCCCCCGCC 
GCATCCTTCC CCGCGGCCAA AGCCCGACGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCGGTGGA GAGCTGCGTG 
CGGAGCTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACGGGCGA GAAGCCCTTC GCCTGCGACG TGTGTGGCCG CCGCTTCGCG 
CGCAGTGACG AGAAGAAACG GCACAGCAAG GTGCACCTAA AGCAGAAGGC GCGCGCGGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CCTTCGCCGC GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065621.1
CDS	146..1582
Translation	MLHLSDFSGSDALLSKPTEGCAHASPELPRLPARDAPSAAAYPGGDFLSWALSSCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGVPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPAARLYQAGAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFSKPLVADLPGGSGVAAPSSPAASFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL

Target ORF information:

RefSeq Version	NM_020596.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus early growth response 4 (Egr4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020596.2

ORF Insert Sequence:

ATGCTCCACC TGAGCGACTT CTCCGGCTCC GACGCGCTTC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACG CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTTTGAGCA GCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCCTGGCA CCCTTCCCCG GTCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGCCCCGATG CCTTGCTGCC GGACCTCTAC 
TCCCCAGATC TGAGTTCGGC CGCCTTTCCG GAGGCGTTTT GGGAGGCAGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCAGGG 
CTGCGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCAGCCTT CAAAGGGCCC 
TATGCCCCCT GGGAGCTGCT GTCGGCCGGG GTCCCGGGGA ACTGTGGGTC GCAGGGGAGC 
TTCCAGACCA CCCCGGAGGC CCGCTTCTCT GCAGTAGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGC CCGGCCGCCA GACTCTACCA GGCAGGGGCC 
TACGACACCT TCTCGTTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCCGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GCCCCTCCGG CGCAGCTGTC CCCTCTAGGC CTGCGCGGTG CCGCCACGGC GGACTTCTCC 
AAACCCCTGG TGGCCGATCT CCCGGGGGGC AGCGGCGTGG CCGCGCCCTC ATCCCCCGCC 
GCATCCTTCC CCGCGGCCAA AGCCCGACGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCGGTGGA GAGCTGCGTG 
CGGAGCTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACGGGCGA GAAGCCCTTC GCCTGCGACG TGTGTGGCCG CCGCTTCGCG 
CGCAGTGACG AGAAGAAACG GCACAGCAAG GTGCACCTAA AGCAGAAGGC GCGCGCGGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CCTTCGCCGC GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Egr4 ( NM_020596.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_065621.1 Mus musculus early growth response 4 (Egr4), mRNA.

Price & Availability↑

CloneID	OMu12032
Clone ID Related Accession (Same CDS sequence)	NM_020596.2 , NM_020596.3
Accession Version	NM_020596.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	early growth response protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK141637.1 and BX528200.1. On Feb 16, 2018 this sequence version replaced NM_020596.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK141637.1, CX201112.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGCTCCACC TGAGCGACTT CTCCGGCTCC GACGCGCTTC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACG CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTTTGAGCA GCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCCTGGCA CCCTTCCCCG GTCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGCCCCGATG CCTTGCTGCC GGACCTCTAC 
TCCCCAGATC TGAGTTCGGC CGCCTTTCCG GAGGCGTTTT GGGAGGCAGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCAGGG 
CTGCGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCAGCCTT CAAAGGGCCC 
TATGCCCCCT GGGAGCTGCT GTCGGCCGGG GTCCCGGGGA ACTGTGGGTC GCAGGGGAGC 
TTCCAGACCA CCCCGGAGGC CCGCTTCTCT GCAGTAGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGC CCGGCCGCCA GACTCTACCA GGCAGGGGCC 
TACGACACCT TCTCGTTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCCGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GCCCCTCCGG CGCAGCTGTC CCCTCTAGGC CTGCGCGGTG CCGCCACGGC GGACTTCTCC 
AAACCCCTGG TGGCCGATCT CCCGGGGGGC AGCGGCGTGG CCGCGCCCTC ATCCCCCGCC 
GCATCCTTCC CCGCGGCCAA AGCCCGACGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCGGTGGA GAGCTGCGTG 
CGGAGCTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACGGGCGA GAAGCCCTTC GCCTGCGACG TGTGTGGCCG CCGCTTCGCG 
CGCAGTGACG AGAAGAAACG GCACAGCAAG GTGCACCTAA AGCAGAAGGC GCGCGCGGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CCTTCGCCGC GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065621.1
CDS	193..1629
Translation	MLHLSDFSGSDALLSKPTEGCAHASPELPRLPARDAPSAAAYPGGDFLSWALSSCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGVPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPAARLYQAGAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFSKPLVADLPGGSGVAAPSSPAASFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL

Target ORF information:

RefSeq Version	NM_020596.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus early growth response 4 (Egr4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020596.3

ORF Insert Sequence:

ATGCTCCACC TGAGCGACTT CTCCGGCTCC GACGCGCTTC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACG CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTTTGAGCA GCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCCTGGCA CCCTTCCCCG GTCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGCCCCGATG CCTTGCTGCC GGACCTCTAC 
TCCCCAGATC TGAGTTCGGC CGCCTTTCCG GAGGCGTTTT GGGAGGCAGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCAGGG 
CTGCGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCAGCCTT CAAAGGGCCC 
TATGCCCCCT GGGAGCTGCT GTCGGCCGGG GTCCCGGGGA ACTGTGGGTC GCAGGGGAGC 
TTCCAGACCA CCCCGGAGGC CCGCTTCTCT GCAGTAGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGC CCGGCCGCCA GACTCTACCA GGCAGGGGCC 
TACGACACCT TCTCGTTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCCGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GCCCCTCCGG CGCAGCTGTC CCCTCTAGGC CTGCGCGGTG CCGCCACGGC GGACTTCTCC 
AAACCCCTGG TGGCCGATCT CCCGGGGGGC AGCGGCGTGG CCGCGCCCTC ATCCCCCGCC 
GCATCCTTCC CCGCGGCCAA AGCCCGACGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCGGTGGA GAGCTGCGTG 
CGGAGCTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACGGGCGA GAAGCCCTTC GCCTGCGACG TGTGTGGCCG CCGCTTCGCG 
CGCAGTGACG AGAAGAAACG GCACAGCAAG GTGCACCTAA AGCAGAAGGC GCGCGCGGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CCTTCGCCGC GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons.
Neural plasticity20111-8(2011)
Ludwig A,Uvarov P,Pellegrino C,Thomas-Crusells J,Schuchmann S,Saarma M,Airaksinen MS,Rivera C

Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(2)644-9(2011 Jan)
Ludwig A,Uvarov P,Soni S,Thomas-Crusells J,Airaksinen MS,Rivera C

EGR4 displays both a cell- and intracellular-specific localization pattern in the developing murine testis.
Developmental dynamics : an official publication of the American Association of Anatomists239(11)3106-14(2010 Nov)
Hogarth CA,Mitchell D,Small C,Griswold M

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
The Journal of neuroscience : the official journal of the Society for Neuroscience29(36)11399-408(2009 Sep)
Fu H,Cai J,Clevers H,Fast E,Gray S,Greenberg R,Jain MK,Ma Q,Qiu M,Rowitch DH,Taylor CM,Stiles CD

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Egr4 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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