Dyrk1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dyrk1b
Entrez Gene ID	13549
Full Name	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms	Mirk
General protein information	Preferred Names dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b Names dual specificity tyrosine-phosphorylation-regulated kinase 1B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006539526.3	XP_006539589.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1
XM_006539527.3	XP_006539590.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
XM_006539528.3	XP_006539591.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3
NM_001271370.1	NP_001258299.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p75
NM_010092.2	NP_034222.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p65
NM_001037957.3	NP_001033046.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p69
XM_006539527.4	XP_006539590.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
XM_030242084.1	XP_030097944.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dyrk1b	NP_001258299.1
Danio rerio (zebrafish)	dyrk1b	NP_001161737.1
	DYRK1B	XP_001089972.1
Bos taurus (cattle)	DYRK1B	NP_001074984.1
Rattus norvegicus (Norway rat)	Dyrk1b	NP_001100966.1
Xenopus tropicalis (tropical clawed frog)	dyrk1a.2	NP_001120373.1
Homo sapiens (human)	DYRK1B	NP_004705.1
Pan troglodytes (chimpanzee)	DYRK1B	XP_512657.2
Canis lupus familiaris (dog)	DYRK1B	XP_005616637.1

Gene Ontology
Bibliography

Related articles in PubMed

Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.
P?rez-S?nchez G, Jim?nez A, Quezada-Ram?rez MA, Estudillo E, Ayala-Sarmiento AE, Mendoza-Hern?ndez G, Hern?ndez-Soto J, Hern?ndez-Hern?ndez FC, C?zares-Raga FE, Segovia J
Journal of cellular physiology(2017 Oct)

Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.
Tsioras K, Papastefanaki F, Politis PK, Matsas R, Gaitanou M
PloS one8(11)e82172(2013)

Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.
Masuda T, Itoh K, Higashitsuji H, Higashitsuji H, Nakazawa N, Sakurai T, Liu Y, Tokuchi H, Fujita T, Zhao Y, Nishiyama H, Tanaka T, Fukumoto M, Ikawa M, Okabe M, Fujita J
Proceedings of the National Academy of Sciences of the United States of America109(27)10885-90(2012 Jul)

G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.
Janumyan Y, Cui Q, Yan L, Sansam CG, Valentin M, Yang E
The Journal of biological chemistry283(49)34108-20(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that functional interactions between BM88/Cend1, RanBPM and Dyrk1B affect the balance between cellular proliferation and differentiation in Neuro 2a cells
Title: Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.

Cirp functions to fine-tune the proliferation of undifferentiated spermatogonia by interacting with Dyrk1b.
Title: Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.

BCL2 and BCL-xL facilitation of G0 quiescence requires BAX, BAK, and p27 phosphorylation by Mirk
Title: G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.

Mirk is anti-apoptotic in myoblasts
Title: Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts.

Mirk is induced within the initial 24 h of myogenic differentiation and enables MEF2 to transcribe the myogenin gene by decreasing the nuclear accumulation of class II HDACs
Title: Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation.

The following Dyrk1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05505	NM_010092.2 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
OMu37993	XM_006539526.3 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu37995	XM_006539528.3 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu37994	XM_006539527.4 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu89344	XM_030242084.1 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu00174	NM_001037957.3 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$370.30 $529.00
OMu06941	NM_001271370.1 Latest version!	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OMu37994	XM_006539527.3	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dyrk1b ( NM_010092.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034222.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu05505
Clone ID Related Accession (Same CDS sequence)	NM_010092.2
Accession Version	NM_010092.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p65
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC141883.4, Y18280.2, CF104460.1 and BX632885.1. On Sep 20, 2012 this sequence version replaced NM_010092.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region compared to variant 1. It encodes isoform p65, also known as isoform a, which is shorter than isoform p69. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.114048.1, Y18280.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034222.1
CDS	260..2029
Translation	MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	NM_010092.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010092.2

ORF Insert Sequence:

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006539526.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539589.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37993
Clone ID Related Accession (Same CDS sequence)	XM_006539526.3
Accession Version	XM_006539526.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006539526.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAATATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGACACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GTTCCAGTGG CTCCTCCAAC GACAACAGAG CCTACCGATA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTATCTCTG CCTCAACATT GCCGGGGACT GGGGCTCAGT TACCCCCATT GCCCCGTTGC 
CTTGGACGAC CCCCATCACC AACATCACCA CCACCCCCAG AGTTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CCTCCAGCAC CTGCCCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACAGGA GGTCGACCAC CTCTCCCACC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG CCTGGGTCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539589.1
CDS	257..2242
Translation	MLAARPPHWGPHRAPAPRGPSAIPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006539526.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539526.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAATATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGACACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GTTCCAGTGG CTCCTCCAAC GACAACAGAG CCTACCGATA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTATCTCTG CCTCAACATT GCCGGGGACT GGGGCTCAGT TACCCCCATT GCCCCGTTGC 
CTTGGACGAC CCCCATCACC AACATCACCA CCACCCCCAG AGTTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CCTCCAGCAC CTGCCCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACAGGA GGTCGACCAC CTCTCCCACC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG CCTGGGTCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006539527.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539590.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu37994
Clone ID Related Accession (Same CDS sequence)	XM_006539527.3 , XM_006539527.4
Accession Version	XM_006539527.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1950bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006539527.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539590.1
CDS	255..2204
Translation	MLAARPPHWGPHRAPAPRGPSAIPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006539527.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539527.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006539528.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539591.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu37995
Clone ID Related Accession (Same CDS sequence)	XM_006539528.3
Accession Version	XM_006539528.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006539528.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGGCG GGGGCTTTGT CTTCAGTTGA TTCTCCCAGT 
GGAACCAGCA GGGGAGCTGG TGCCCTGACT ACTGTCCCCT CCCCCAGATC TACCAGTATA 
TCCAGAGCCG CTTCTACCGC TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA 
TTGACATGTG GTCCCTGGGC TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA 
GTGGCTCTAA TGAGGTGGAC CAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539591.1
CDS	275..1501
Translation	MLAARPPHWGPHRAPAPRGPSAIPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRAGALSSVDSPSGTSRGAGALTTVPSPRSTSISRAASTAHPRCSWVHPMTWPLTCGPWAASSWRCTPESPSSVALMRWTR

Target ORF information:

RefSeq Version	XM_006539528.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539528.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGGCG GGGGCTTTGT CTTCAGTTGA TTCTCCCAGT 
GGAACCAGCA GGGGAGCTGG TGCCCTGACT ACTGTCCCCT CCCCCAGATC TACCAGTATA 
TCCAGAGCCG CTTCTACCGC TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA 
TTGACATGTG GTCCCTGGGC TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA 
GTGGCTCTAA TGAGGTGGAC CAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006539527.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539590.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu37994
Clone ID Related Accession (Same CDS sequence)	XM_006539527.3 , XM_006539527.4
Accession Version	XM_006539527.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1950bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006539527.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539590.1
CDS	291..2240
Translation	MLAARPPHWGPHRAPAPRGPSAIPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006539527.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539527.4

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_030242084.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030097944.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.

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CloneID	OMu89344
Clone ID Related Accession (Same CDS sequence)	XM_030242084.1
Accession Version	XM_030242084.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1806bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAATATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGACACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GTTCCAGTGG CTCCTCCAAC GACAACAGAG CCTACCGATA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTATCTCTG CCTCAACATT GCCGGGGACT GGGGCTCAGT TACCCCCATT GCCCCGTTGC 
CTTGGACGAC CCCCATCACC AACATCACCA CCACCCCCAG AGTTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CCTCCAGCAC CTGCCCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACAGGA GGTCGACCAC CTCTCCCACC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG CCTGGGTCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030097944.1
CDS	285..2090
Translation	MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_030242084.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030242084.1

ORF Insert Sequence:

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAATATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGACACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GTTCCAGTGG CTCCTCCAAC GACAACAGAG CCTACCGATA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTATCTCTG CCTCAACATT GCCGGGGACT GGGGCTCAGT TACCCCCATT GCCCCGTTGC 
CTTGGACGAC CCCCATCACC AACATCACCA CCACCCCCAG AGTTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CCTCCAGCAC CTGCCCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACAGGA GGTCGACCAC CTCTCCCACC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG CCTGGGTCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( NM_001037957.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001033046.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1, mRNA.

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CloneID	OMu00174
Clone ID Related Accession (Same CDS sequence)	NM_001037957.3
Accession Version	NM_001037957.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1890bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p69
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC141883.4. On Sep 20, 2012 this sequence version replaced NM_001037957.2. Transcript Variant: This variant (1) represents the longest transcript and encodes isoform p69, also known as isoform b. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019545.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CCGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033046.1
CDS	260..2149
Translation	MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	NM_001037957.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037957.3

ORF Insert Sequence:

ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CCGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( NM_001271370.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001258299.1 Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 4, mRNA.

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CloneID	OMu06941
Clone ID Related Accession (Same CDS sequence)	NM_001271370.1
Accession Version	NM_001271370.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-04
Organism	Mus musculus(house mouse)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p75
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ537610.1 and AC141883.4. Transcript Variant: This variant (4), uses an alternate 5' structure, compared to variant 1. This difference causes translation initiation at an upstream AUG and results in an isoform (p75), also known as isoform c, that has a longer N-terminus, compared to isoform p69. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ537610.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CCGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258299.1
CDS	33..2102
Translation	MLAARPPHWGPHRAPAPRGPSAIPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	NM_001271370.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271370.1

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGT CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCATCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACGCCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCTTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTACTAC CTGATGTGCG GCTCCTGCCC CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
GCCTCAGCCC CGCTGCGCAA GCTCTCGGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAACCAC GGTTATGATG ACGACAACCA CGACTACATT 
GTGCGCAGTG GCGAGCGCTG GCTAGAGCGC TATGAGATTG ACTCTCTTAT TGGCAAAGGC 
TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTACG GCTGTTGGAG 
CTGATGAACC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTTAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG GGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CTCTGCTCTT TCTGGCCACC CCCGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 
GGCAGTTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCCGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TTGACATGTG GTCCCTGGGC 
TGCATCCTCG TGGAGATGCA CACCGGAGAG CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GTATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCCATGCT GGAACAGGCA 
CCCAAGGCTC GAAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CCGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAAT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGACAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAACGACAAC 
AGAGCCTACC GATACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTATC TCTGCCTCAA CATTGCCGGG GACTGGGGCT 
CAGTTACCCC CATTGCCCCG TTGCCTTGGA CGACCCCCAT CACCAACATC ACCACCACCC 
CCAGAGTTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCCTCCA 
GCACCTGCCC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGA 
CCACCTCTCC CACCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG TCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.
Journal of cellular physiology(2017 Oct)
P?rez-S?nchez G,Jim?nez A,Quezada-Ram?rez MA,Estudillo E,Ayala-Sarmiento AE,Mendoza-Hern?ndez G,Hern?ndez-Soto J,Hern?ndez-Hern?ndez FC,C?zares-Raga FE,Segovia J

Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.
PloS one8(11)e82172(2013)
Tsioras K,Papastefanaki F,Politis PK,Matsas R,Gaitanou M

Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.
Proceedings of the National Academy of Sciences of the United States of America109(27)10885-90(2012 Jul)
Masuda T,Itoh K,Higashitsuji H,Higashitsuji H,Nakazawa N,Sakurai T,Liu Y,Tokuchi H,Fujita T,Zhao Y,Nishiyama H,Tanaka T,Fukumoto M,Ikawa M,Okabe M,Fujita J

G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.
The Journal of biological chemistry283(49)34108-20(2008 Dec)
Janumyan Y,Cui Q,Yan L,Sansam CG,Valentin M,Yang E

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Dyrk1b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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