Slc26a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc26a2
Entrez Gene ID	13521
Full Name	solute carrier family 26 (sulfate transporter), member 2
Synonyms	Dtd,ST-OB
General protein information	Preferred Names solute carrier family 26 (sulfate transporter), member 2 Names sulfate transporter diastrophic dysplasia protein homolog solute carrier family 26 member 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_007885.2	NP_031911.1	sulfate transporter

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc26a2	NP_476468.1
Danio rerio (zebrafish)	slc26a2	XP_005173217.1
Mus musculus (house mouse)	Slc26a2	NP_031911.1
Gallus gallus (chicken)	SLC26A2	XP_425183.4
Pan troglodytes (chimpanzee)	SLC26A2	XP_001164642.1
Canis lupus familiaris (dog)	SLC26A2	XP_855107.1
Bos taurus (cattle)	SLC26A2	NP_001035615.1
Homo sapiens (human)	SLC26A2	NP_000103.2
	SLC26A2	XP_001098562.2
Arabidopsis thaliana (thale cress)	SULTR3;4	NP_188220.1
Oryza sativa (rice)	Os06g0143700	NP_001056778.1
Xenopus tropicalis (tropical clawed frog)	LOC100494417	XP_002943195.1

Gene Ontology
Bibliography

Related articles in PubMed

N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia.
Monti L, Paganini C, Lecci S, De Leonardis F, Hay E, Cohen-Solal M, Villani S, Superti-Furga A, Tenni R, Forlino A, Rossi A
Human molecular genetics24(19)5570-80(2015 Oct)

Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene.
Cai T, Yang L, Cai W, Guo S, Yu P, Li J, Hu X, Yan M, Shao Q, Jin Y, Sun ZS, Luo ZJ
Proceedings of the National Academy of Sciences of the United States of America112(26)8064-9(2015 Jun)

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Maga AM, Navarro N, Cunningham ML, Cox TC
Frontiers in physiology692(2015)

Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion.
Spyroglou A, Bozoglu T, Rawal R, De Leonardis F, Sterner C, Boulkroun S, Benecke AG, Monti L, Zennaro MC, Petersen AK, D?ring A, Rossi A, Bidlingmaier M, Warth R, Gieger C, Reincke M, Beuschlein F
Hypertension (Dallas, Tex. : 1979)63(5)1102-9(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion.
Title: Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion.

These findings reveal multiple roles for Slc26a2 in chondrocyte biology and emphasize the importance of Slc26a2-mediated protein sulfation in cell signaling
Title: Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functions.

a Slc26a2 mutation results in matrix disruptions, growth, and degradation of cartilage with impaired sulfation
Title: Matrix disruptions, growth, and degradation of cartilage with impaired sulfation.

Characterize transport of oxalate and sulfate by human SLC26A2 and mouse Slc26a2 expressed in Xenopus oocytes.
Title: Regulated transport of sulfate and oxalate by SLC26A2/DTDST.

Homozygous mutant mice for SLC26A2 were characterized by skeletal dysplasia with chondrocytes of irregular size, delay in the formation of the secondary ossification centre and osteoporosis of long bones.
Title: Insights from a transgenic mouse model on the role of SLC26A2 in health and disease.

The following Slc26a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc26a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16230	NM_007885.2 Latest version!	Mus musculus solute carrier family 26 (sulfate transporter), member 2 (Slc26a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc26a2 ( NM_007885.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031911.1 Mus musculus solute carrier family 26 (sulfate transporter), member 2 (Slc26a2), mRNA.

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CloneID	OMu16230
Clone ID Related Accession (Same CDS sequence)	NM_007885.2
Accession Version	NM_007885.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	sulfate transporter
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK052942.1 and AC148012.5. On Dec 20, 2006 this sequence version replaced NM_007885.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D42049.1, BC028345.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTTCAG AAAATAAAGA GCAGCATGAC CTCTCACCGA GGGACTTACC TGAAGAAGCC 
TTTGGTTTCC CATCTGAGCT CCCCCTGGAG ACTCAAAGAA GGTCAGGCAC TGACTTGAGG 
CAGTCTGAGA CCGGTCATGG CCGGAGAGCT TTCCGTAGGA TCCACATGGA GCTCCGTGAG 
AAACCAGACA CAGACATCAA ACAGTTTGTC ATCAGAGAGC TCCAGAAGAG TTGCCAGTGC 
AGCGCAGCCA AAGTCAGAGA CGGGGCTTTT GATTTCTTTC CTGTTTTGCG GTGGCTCCCA 
AAATATGACC TGAAGAAAAA CATTTTAGGT GATGTGATGT CTGGCCTGAT TGTGGGTATC 
CTGTTGGTGC CCCAGTCCAT TGCTTACTCC CTGCTGGCTG GCCAGGAGCC TATATATGGT 
CTATATACAT CATTTTTTGC CAGCATTATT TATTTCCTGT TTGGTACATC CCGCCACATC 
TCTGTGGGCA TTTTTGGAAT ACTGTGCCTT ATGATTGGTG AGGTTGTTGA CCGAGAACTA 
CATAAAGCCT GCCCTGACAC TGATGCTACG TCATCTTCGA TAGCAGTGTT TTCAAGTGGA 
TGTGTGGTTG TAAACCATAC ATTAGACGGA CTCTGTGATA AAAGCTGCTA TGCAATTAAA 
ATTGGCAGCA CTGTGACCTT CATGGCTGGA GTTTATCAGG TAGCAATGGG CTTCTTTCAA 
GTGGGCTTTG TCTCTGTCTA CCTCTCCGAC GCCTTGCTGA GCGGGTTTGT CACTGGCGCC 
TCCTTCACCA TCCTCACGTC TCAGGCCAAG TACCTCCTTG GGCTGAGCCT TCCTCGGAGT 
CATGGTGTCG GCTCAGTCAT TACTACCTGG ATCCACATCT TCAGAAACAT CCGTAACACC 
AACATCTGTG ATCTCATCAC CAGCCTTTTA TGTCTTCTGG TCCTCGTGCC ATCCAAAGAA 
CTCAATGAGC ACTTCAAGGA CAAGCTCAAG GCTCCAATTC CGGTCGAGCT CATTGTCGTT 
GTGGCGGCCA CATTGGCTTC TCATTTTGGA AAACTAAATG GGAATTACAA TTCCAGTATT 
GCTGGACACA TTCCCACTGG GTTTATGCCA CCCAAAGCAC CAGACTGGAG CCTCATTCCT 
AATGTGGCTG TAGATGCAAT AGCTATTTCT ATCATTGGTT TTGCTATCAC TGTATCACTT 
TCTGAGATGT TTGCCAAGAA ACATGGCTAC ACGGTCAAAG CAAACCAAGA AATGTATGCC 
ATTGGCTTTT GCAATATCAT ACCTTCCTTC TTCCACTGCA TAACTACTAG TGCAGCTCTT 
GCAAAGACAT TGGTTAAAGA GTCAACAGGC TGCCAGACGC AGCTGTCAGC TATAGTGACA 
GCCCTTGTCC TTTTGTTGGT CCTTCTGGTA ATAGCTCCTT TATTCTATTC CCTTCAAAAA 
TGTGTCCTTG GTGTGATCAC TATTGTAAAT CTCCGGGGCG CACTTCTGAA ATTTAGAGAC 
CTGCCAAAGA TGTGGAGGCT AAGCAGAATG GATACAGTTA TCTGGTTTGT GACTATGCTG 
TCCTCCGCTC TGTTAAGCAC TGAAATAGGC CTGCTGGTTG GGGTTTGTTT TTCAATGTTC 
TGTGTGATCC TCCGTACTCA GAAGCCAAAG AATTCACTGC TTGGTTTAGA AGAAGAATCT 
GAAACCTTTG AATCCATTTC CACTTACAAG AACCTTCGGA GCAAGTCCGG CATCAAGGTT 
TTCCGCTTCA TAGCCCCTCT CTACTACATA AACAAAGAGT GCTTTAAATC AGCTTTGTAC 
AAGAAAGCTC TTAACCCAGT CTTGGTAAAG GCAGCTTGGA AAAAGGCAGC AAAGAGAAAA 
CTCAAAGAAG AAATGGTGAC CTTTCGTGGG GACCCGGATG AAGTTTCAAT GCAGCTTTCC 
CATGATCCCT TGGAGGTGCA CACTATCGTG ATCGACTGTA GTGCCATACA GTTTTTAGAC 
ACAGCAGGAA TCCACACACT GAAAGAAGTT CGCCGGGATT ATGAAGCCGT TGGGATCCAG 
GTTTTACTGG CGCAGTGCAA TCCTTCTGTG AGGGATTCCT TGGCCAGAGG AGAATATTGC 
AAAAAGGAAG AGGAAACCCT TCTCTTCTAC AGTCTGTCTG AAGCAGTAGC CTTTGCAGAA 
GACTCTCAGA ATCAGAAAGG GGTGTGTGTT GTCAACGGTC TGAGTCTCTC TGGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031911.1
CDS	360..2579
Translation	MSSENKEQHDLSPRDLPEEAFGFPSELPLETQRRSGTDLRQSETGHGRRAFRRIHMELREKPDTDIKQFVIRELQKSCQCSAAKVRDGAFDFFPVLRWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDTDATSSSIAVFSSGCVVVNHTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSHGVGSVITTWIHIFRNIRNTNICDLITSLLCLLVLVPSKELNEHFKDKLKAPIPVELIVVVAATLASHFGKLNGNYNSSIAGHIPTGFMPPKAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTALVLLLVLLVIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQKPKNSLLGLEEESETFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKALNPVLVKAAWKKAAKRKLKEEMVTFRGDPDEVSMQLSHDPLEVHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAVGIQVLLAQCNPSVRDSLARGEYCKKEEETLLFYSLSEAVAFAEDSQNQKGVCVVNGLSLSGD

Target ORF information:

RefSeq Version	NM_007885.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 26 (sulfate transporter), member 2 (Slc26a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007885.2

ORF Insert Sequence:

ATGTCTTCAG AAAATAAAGA GCAGCATGAC CTCTCACCGA GGGACTTACC TGAAGAAGCC 
TTTGGTTTCC CATCTGAGCT CCCCCTGGAG ACTCAAAGAA GGTCAGGCAC TGACTTGAGG 
CAGTCTGAGA CCGGTCATGG CCGGAGAGCT TTCCGTAGGA TCCACATGGA GCTCCGTGAG 
AAACCAGACA CAGACATCAA ACAGTTTGTC ATCAGAGAGC TCCAGAAGAG TTGCCAGTGC 
AGCGCAGCCA AAGTCAGAGA CGGGGCTTTT GATTTCTTTC CTGTTTTGCG GTGGCTCCCA 
AAATATGACC TGAAGAAAAA CATTTTAGGT GATGTGATGT CTGGCCTGAT TGTGGGTATC 
CTGTTGGTGC CCCAGTCCAT TGCTTACTCC CTGCTGGCTG GCCAGGAGCC TATATATGGT 
CTATATACAT CATTTTTTGC CAGCATTATT TATTTCCTGT TTGGTACATC CCGCCACATC 
TCTGTGGGCA TTTTTGGAAT ACTGTGCCTT ATGATTGGTG AGGTTGTTGA CCGAGAACTA 
CATAAAGCCT GCCCTGACAC TGATGCTACG TCATCTTCGA TAGCAGTGTT TTCAAGTGGA 
TGTGTGGTTG TAAACCATAC ATTAGACGGA CTCTGTGATA AAAGCTGCTA TGCAATTAAA 
ATTGGCAGCA CTGTGACCTT CATGGCTGGA GTTTATCAGG TAGCAATGGG CTTCTTTCAA 
GTGGGCTTTG TCTCTGTCTA CCTCTCCGAC GCCTTGCTGA GCGGGTTTGT CACTGGCGCC 
TCCTTCACCA TCCTCACGTC TCAGGCCAAG TACCTCCTTG GGCTGAGCCT TCCTCGGAGT 
CATGGTGTCG GCTCAGTCAT TACTACCTGG ATCCACATCT TCAGAAACAT CCGTAACACC 
AACATCTGTG ATCTCATCAC CAGCCTTTTA TGTCTTCTGG TCCTCGTGCC ATCCAAAGAA 
CTCAATGAGC ACTTCAAGGA CAAGCTCAAG GCTCCAATTC CGGTCGAGCT CATTGTCGTT 
GTGGCGGCCA CATTGGCTTC TCATTTTGGA AAACTAAATG GGAATTACAA TTCCAGTATT 
GCTGGACACA TTCCCACTGG GTTTATGCCA CCCAAAGCAC CAGACTGGAG CCTCATTCCT 
AATGTGGCTG TAGATGCAAT AGCTATTTCT ATCATTGGTT TTGCTATCAC TGTATCACTT 
TCTGAGATGT TTGCCAAGAA ACATGGCTAC ACGGTCAAAG CAAACCAAGA AATGTATGCC 
ATTGGCTTTT GCAATATCAT ACCTTCCTTC TTCCACTGCA TAACTACTAG TGCAGCTCTT 
GCAAAGACAT TGGTTAAAGA GTCAACAGGC TGCCAGACGC AGCTGTCAGC TATAGTGACA 
GCCCTTGTCC TTTTGTTGGT CCTTCTGGTA ATAGCTCCTT TATTCTATTC CCTTCAAAAA 
TGTGTCCTTG GTGTGATCAC TATTGTAAAT CTCCGGGGCG CACTTCTGAA ATTTAGAGAC 
CTGCCAAAGA TGTGGAGGCT AAGCAGAATG GATACAGTTA TCTGGTTTGT GACTATGCTG 
TCCTCCGCTC TGTTAAGCAC TGAAATAGGC CTGCTGGTTG GGGTTTGTTT TTCAATGTTC 
TGTGTGATCC TCCGTACTCA GAAGCCAAAG AATTCACTGC TTGGTTTAGA AGAAGAATCT 
GAAACCTTTG AATCCATTTC CACTTACAAG AACCTTCGGA GCAAGTCCGG CATCAAGGTT 
TTCCGCTTCA TAGCCCCTCT CTACTACATA AACAAAGAGT GCTTTAAATC AGCTTTGTAC 
AAGAAAGCTC TTAACCCAGT CTTGGTAAAG GCAGCTTGGA AAAAGGCAGC AAAGAGAAAA 
CTCAAAGAAG AAATGGTGAC CTTTCGTGGG GACCCGGATG AAGTTTCAAT GCAGCTTTCC 
CATGATCCCT TGGAGGTGCA CACTATCGTG ATCGACTGTA GTGCCATACA GTTTTTAGAC 
ACAGCAGGAA TCCACACACT GAAAGAAGTT CGCCGGGATT ATGAAGCCGT TGGGATCCAG 
GTTTTACTGG CGCAGTGCAA TCCTTCTGTG AGGGATTCCT TGGCCAGAGG AGAATATTGC 
AAAAAGGAAG AGGAAACCCT TCTCTTCTAC AGTCTGTCTG AAGCAGTAGC CTTTGCAGAA 
GACTCTCAGA ATCAGAAAGG GGTGTGTGTT GTCAACGGTC TGAGTCTCTC TGGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia.
Human molecular genetics24(19)5570-80(2015 Oct)
Monti L,Paganini C,Lecci S,De Leonardis F,Hay E,Cohen-Solal M,Villani S,Superti-Furga A,Tenni R,Forlino A,Rossi A

Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene.
Proceedings of the National Academy of Sciences of the United States of America112(26)8064-9(2015 Jun)
Cai T,Yang L,Cai W,Guo S,Yu P,Li J,Hu X,Yan M,Shao Q,Jin Y,Sun ZS,Luo ZJ

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Frontiers in physiology692(2015)
Maga AM,Navarro N,Cunningham ML,Cox TC

Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion.
Hypertension (Dallas, Tex. : 1979)63(5)1102-9(2014 May)
Spyroglou A,Bozoglu T,Rawal R,De Leonardis F,Sterner C,Boulkroun S,Benecke AG,Monti L,Zennaro MC,Petersen AK,D?ring A,Rossi A,Bidlingmaier M,Warth R,Gieger C,Reincke M,Beuschlein F

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Slc26a2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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