Slc26a3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc26a3
Entrez Gene ID	13487
Full Name	solute carrier family 26, member 3
Synonyms	9030623B18Rik,9130013M11Rik,AV376035,Dra
General protein information	Preferred Names solute carrier family 26, member 3 Names chloride anion exchanger down-regulated in adenoma
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12 A2\|12 13.45 cM
Summary	This gene encodes a member of the solute carrier/sulfate transporter family. The encoded protein is predominantly expressed in the intestine where it is essential for chloride absorption. Disruption of this gene results in chloride-rich diarrhea and compensatory up-regulation of ion-absorbing transporters. [provided by RefSeq, Dec 2012].

mRNA and Protein(s)

mRNA	Protein	Name
XM_011243811.1	XP_011242113.1	chloride anion exchanger isoform X1
XM_017314950.1	XP_017170439.1	chloride anion exchanger isoform X1
XM_011243812.1	XP_011242114.1	chloride anion exchanger isoform X2
NM_021353.3	NP_067328.1	chloride anion exchanger

Pathways from BioSystems

Homologies

	SLC26A3	XP_001090155.2
Gallus gallus (chicken)	SLC26A3	NP_001186373.1
Homo sapiens (human)	SLC26A3	NP_000102.1
Mus musculus (house mouse)	Slc26a3	NP_067328.1
Rattus norvegicus (Norway rat)	Slc26a3	NP_446207.1
Pan troglodytes (chimpanzee)	SLC26A3	XP_527858.2
Bos taurus (cattle)	SLC26A3	NP_001077145.1
Caenorhabditis elegans (roundworm)	sulp-6	NP_491138.2
Xenopus tropicalis (tropical clawed frog)	LOC101731072	XP_004913063.1
Canis lupus familiaris (dog)	SLC26A3	XP_540380.3
Danio rerio (zebrafish)	slc26a3	NP_001129155.1
Danio rerio (zebrafish)	si:dkey-31f5.1	NP_001035265.1

Gene Ontology
Bibliography

Related articles in PubMed

Tumor necrosis factor-? acts reciprocally with solute carrier family 26, member 3, (downregulated-in-adenoma) and reduces its expression, leading to intestinal inflammation.
Ding X, Li D, Li M, Tian D, Yu H, Yu Q
International journal of molecular medicine41(3)1224-1232(2018 Mar)

SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis.
Ding X, Li D, Li M, Wang H, He Q, Wang Y, Yu H, Tian D, Yu Q
Laboratory investigation; a journal of technical methods and pathology(2018 Jan)

Activation of Nuclear Factor-?B by Tumor Necrosis Factor in Intestinal Epithelial Cells and Mouse Intestinal Epithelia Reduces Expression of the Chloride Transporter SLC26A3.
Kumar A, Chatterjee I, Gujral T, Alakkam A, Coffing H, Anbazhagan AN, Borthakur A, Saksena S, Gill RK, Alrefai WA, Dudeja PK
Gastroenterology153(5)1338-1350.e3(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In intestinal cells, TNF activates NF-kappaB, which reduces expression of the Cl(-) / HCO3(-) exchanger SLC26A3, via direct binding to the promoter region.
Title: Activation of Nuclear Factor-?B by Tumor Necrosis Factor in Intestinal Epithelial Cells and Mouse Intestinal Epithelia Reduces Expression of the Chloride Transporter SLC26A3.

This study showed that transepithelial sulfate fluxes across the mouse distal ileum demonstrating that DRA (and to a lesser extent, PAT1) secretes sulfate with significant implications for intestinal sulfate absorption and overall homeostasis.
Title: Loss of the anion exchanger DRA (Slc26a3), or PAT1 (Slc26a6), alters sulfate transport by the distal ileum and overall sulfate homeostasis.

expressed in ameloblasts but not alone critical for formation of dental enamel
Title: Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.

DRA surface expression was reduced partly via an increase in DRA endocytosis and a decrease in exocytosis
Title: Mechanisms of DRA recycling in intestinal epithelial cells: effect of enteropathogenic E. coli.

Data indicate that solute carrier family 26, member 3 protein (Slc26a3) is expressed in male reproductive tract, and its expression pattern is related to the function.
Title: [Expression pattern of congenital chloride diarrhea pathogenic gene Slc26a3 in the reproductive tract of male rodents].

The following Slc26a3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc26a3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu67563	XM_011243812.1 Latest version!	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu12230	NM_021353.3 Latest version!	Mus musculus solute carrier family 26, member 3 (Slc26a3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu12230	XM_011243811.1 Latest version!	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu12230	XM_017314950.1 Latest version!	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc26a3 ( XM_011243812.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242114.1 Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu67563
Clone ID Related Accession (Same CDS sequence)	XM_011243812.1
Accession Version	XM_011243812.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	chloride anion exchanger isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTCTTG GATTTCAACC CCCTATTACA CCCAGCGTGG AAGTTTTCCA AGACACCATA 
GGAGACAGCT TCGGCATCGC GATCGTCGGC TTTGCCGTGG CCTTTTCCGT TGCCAGCGTG 
TACTCCCTCA AATACGATTA TCCGATTGAT GGCAATCAGG AGTTAATTGC CTTGGGAGTG 
AGCAACATAT TCACTGGAGC ATTCAAAGGA TTTGCAGGGA GCACAGCCCT TTCCAGATCA 
GGGGTTCAGG AGAGCACGGG AGGCAAAACA CAGGTTGCGG GGCTTCTCTC AGCTGTCATC 
GTGTTGATCG TCATAGTTGC CATTGGGTTT CTTCTGCAGC CGCTACAAAA GTCTGTCCTG 
GCAGCGCTAG CACTCGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGAAAA AGGATAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCGCCATT 
GTCCTTGGAC TCGGATTAGG CCTGGCGGCA AGTGTAGCAT TTCAACTCCT AACTATTGTG 
TTCAGGACCC AATTTCCAAA GTGCAGCACA TTGGCTAATG TTGGAAGGAG CAACATCTAC 
AAGAATAAAA AGAATTATGC CGAAGTGTAT GAGCCTGAAG GAGTGAAAAT TTTTAGATGT 
CCATCTCCAA TCTACTTCGC AAACATTGGT TTCTTTAAGC AGAAACTTAT TGATGCTGTT 
GGCTTTAGCC CACTTCGAAT TCTACGGAAG CGCAACAAAG CTTTGAAGAA AATCCGAAAA 
CTGCAGAAAC GAGGTCTGAT ACAGATGACA CCTAAAGGGT TTATATGCAC CTCTGACGGT 
TTCAAAGACT CCGACGAAGA ATTGGACAAC AACCAGATAG AAGAACTTGA TCAGCCGATC 
AATACCACAG ATCTGCCCTT TGACATAGAC TGGAACGGGG ATCTTCCCCT CAACATCACC 
ATCCCCAAAA TCAGCCTCCA CAGCCTCATC CTCGATTTTT CAGCAGTGTC TTTCCTTGAC 
GTCTCCTCAA TGAGGGGCCT CAGAACGATT TTACAAGAAT TTATTAGGAT CAAGGTGGAC 
GTATATATTG TGGGAACCGA TGATGATTTC ATTGACAAAC TTGCTCGGTG TGAATTCTTC 
GATGATGAAG TCACAGACTC AATATTTTTC TTAACAATCC ATGATGCTAT TTTGCATATT 
TTGATGAAGA AGGACTACAG CACTTCAAAG TTTAATTCCA GCCAGGAAAA AGAAAGGAAA 
TTTGACTTTA CCATAAATAC AAATGGAGGA CTACGTAATC GGGAATGTCA GGTACCAGTT 
GAAACGAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242114.1
CDS	334..1668
Translation	MSLGFQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF

Target ORF information:

RefSeq Version	XM_011243812.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243812.1

ORF Insert Sequence:

ATGAGTCTTG GATTTCAACC CCCTATTACA CCCAGCGTGG AAGTTTTCCA AGACACCATA 
GGAGACAGCT TCGGCATCGC GATCGTCGGC TTTGCCGTGG CCTTTTCCGT TGCCAGCGTG 
TACTCCCTCA AATACGATTA TCCGATTGAT GGCAATCAGG AGTTAATTGC CTTGGGAGTG 
AGCAACATAT TCACTGGAGC ATTCAAAGGA TTTGCAGGGA GCACAGCCCT TTCCAGATCA 
GGGGTTCAGG AGAGCACGGG AGGCAAAACA CAGGTTGCGG GGCTTCTCTC AGCTGTCATC 
GTGTTGATCG TCATAGTTGC CATTGGGTTT CTTCTGCAGC CGCTACAAAA GTCTGTCCTG 
GCAGCGCTAG CACTCGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGAAAA AGGATAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCGCCATT 
GTCCTTGGAC TCGGATTAGG CCTGGCGGCA AGTGTAGCAT TTCAACTCCT AACTATTGTG 
TTCAGGACCC AATTTCCAAA GTGCAGCACA TTGGCTAATG TTGGAAGGAG CAACATCTAC 
AAGAATAAAA AGAATTATGC CGAAGTGTAT GAGCCTGAAG GAGTGAAAAT TTTTAGATGT 
CCATCTCCAA TCTACTTCGC AAACATTGGT TTCTTTAAGC AGAAACTTAT TGATGCTGTT 
GGCTTTAGCC CACTTCGAAT TCTACGGAAG CGCAACAAAG CTTTGAAGAA AATCCGAAAA 
CTGCAGAAAC GAGGTCTGAT ACAGATGACA CCTAAAGGGT TTATATGCAC CTCTGACGGT 
TTCAAAGACT CCGACGAAGA ATTGGACAAC AACCAGATAG AAGAACTTGA TCAGCCGATC 
AATACCACAG ATCTGCCCTT TGACATAGAC TGGAACGGGG ATCTTCCCCT CAACATCACC 
ATCCCCAAAA TCAGCCTCCA CAGCCTCATC CTCGATTTTT CAGCAGTGTC TTTCCTTGAC 
GTCTCCTCAA TGAGGGGCCT CAGAACGATT TTACAAGAAT TTATTAGGAT CAAGGTGGAC 
GTATATATTG TGGGAACCGA TGATGATTTC ATTGACAAAC TTGCTCGGTG TGAATTCTTC 
GATGATGAAG TCACAGACTC AATATTTTTC TTAACAATCC ATGATGCTAT TTTGCATATT 
TTGATGAAGA AGGACTACAG CACTTCAAAG TTTAATTCCA GCCAGGAAAA AGAAAGGAAA 
TTTGACTTTA CCATAAATAC AAATGGAGGA CTACGTAATC GGGAATGTCA GGTACCAGTT 
GAAACGAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc26a3 ( NM_021353.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067328.1 Mus musculus solute carrier family 26, member 3 (Slc26a3), mRNA.

Price & Availability↑

CloneID	OMu12230
Clone ID Related Accession (Same CDS sequence)	XM_011243811.1 , XM_017314950.1 , NM_021353.3
Accession Version	NM_021353.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Mus musculus(house mouse)
Product	chloride anion exchanger
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK018566.1, BC139271.1 and CR974423.21. On Dec 16, 2012 this sequence version replaced NM_021353.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF136751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067328.1
CDS	213..2486
Translation	MIEAIGNQYVVARPVYSTKTFGEEFKKTHRHHKTFLDHLKGCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVVSDPNASSELSSSSTENDSFIEEKVMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKEINQRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLGFQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF

Target ORF information:

RefSeq Version	NM_021353.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 26, member 3 (Slc26a3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021353.3

ORF Insert Sequence:

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc26a3 ( XM_011243811.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242113.1 Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu12230
Clone ID Related Accession (Same CDS sequence)	XM_011243811.1 , XM_017314950.1 , NM_021353.3
Accession Version	XM_011243811.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	chloride anion exchanger isoform X1
Comment

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011242113.1

Translation

MIEAIGNQYVVARPVYSTKTFGEEFKKTHRHHKTFLDHLKGCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVVSDPNASSELSSSSTENDSFIEEKVMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKEINQRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLGFQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF

Target ORF information:

RefSeq Version	XM_011243811.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243811.1

ORF Insert Sequence:

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc26a3 ( XM_017314950.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170439.1 Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.

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CloneID	OMu12230
Clone ID Related Accession (Same CDS sequence)	XM_011243811.1 , XM_017314950.1 , NM_021353.3
Accession Version	XM_017314950.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	chloride anion exchanger isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170439.1
CDS	188..2461
Translation	MIEAIGNQYVVARPVYSTKTFGEEFKKTHRHHKTFLDHLKGCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVVSDPNASSELSSSSTENDSFIEEKVMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKEINQRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLGFQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF

Target ORF information:

RefSeq Version	XM_017314950.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 26, member 3 (Slc26a3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314950.1

ORF Insert Sequence:

ATGATCGAAG CCATAGGGAA TCAGTATGTG GTGGCCAGAC CGGTGTACTC CACAAAGACT 
TTTGGAGAGG AGTTTAAGAA GACGCACAGA CATCACAAGA CATTCCTGGA CCATCTCAAA 
GGGTGTTGTA GCTGCTCCTC ACAGAAGGCC AAGAAAATCG CCCTGTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCCTA CAAGATAAAG GAATGGCTTC TCAGTGACAT CGTCTCTGGC 
ATCAGCACCG GGCTGGTGGC TGTACTGCAA GGTTTAGCAT TTGCTCTGCT GGTCAACATC 
CCTCCAGCCT ACGGGTTGTA CGCAGCCTTT TTCCCAGTCA TAACCTACTT TTTCTTGGGC 
ACATCTAGAC ACATATCTGT GGGTCCATTT CCAGTTCTGA GTATGATGGT GGGAGTTGTC 
GTTACAAGAG TGGTCTCGGA CCCCAATGCT TCTTCAGAGT TGTCCTCAAG CTCCACAGAA 
AATGACTCGT TCATAGAGGA GAAAGTAATG GTGGCTGCAT CAGTAACTGT TCTTTCTGGA 
ATCATTCAGT TGCTCCTGGG GGTTCTGCAG GTCGGCTTTG TGGTGATATA CCTATCCGAG 
TCCCTAATCA GTGGCTTCAC CACGGCTGCT GCCATTCACG TTCTGGTTTC TCAACTGAAA 
TTCATGCTAC AGCTGCCAGT CCCAGCATAC AGCGACCCAT TCTCTATATT CAAAGTCCTG 
GAGTCGGTCT TCACACAAAT TCAGAAGACG AACATCGCAG ACCTTGTGAC ATCTGTGATT 
ATTCTAGTGG TCGTGTTTGT CTTTAAAGAA ATCAATCAGC GTTACAGAAG CAAACTTCCG 
GTGCCCATCC CCATCGAACT CATCATGACT GTAATTGCCA CAGGTGTGTC CTATGGCTGT 
AACTTTGAAG ACAGGTTTGG CGTGGCCGTG GTTGGGAACA TGAGTCTTGG ATTTCAACCC 
CCTATTACAC CCAGCGTGGA AGTTTTCCAA GACACCATAG GAGACAGCTT CGGCATCGCG 
ATCGTCGGCT TTGCCGTGGC CTTTTCCGTT GCCAGCGTGT ACTCCCTCAA ATACGATTAT 
CCGATTGATG GCAATCAGGA GTTAATTGCC TTGGGAGTGA GCAACATATT CACTGGAGCA 
TTCAAAGGAT TTGCAGGGAG CACAGCCCTT TCCAGATCAG GGGTTCAGGA GAGCACGGGA 
GGCAAAACAC AGGTTGCGGG GCTTCTCTCA GCTGTCATCG TGTTGATCGT CATAGTTGCC 
ATTGGGTTTC TTCTGCAGCC GCTACAAAAG TCTGTCCTGG CAGCGCTAGC ACTCGGAAAC 
TTAAAGGGAA TGCTGATGCA GTTTGCTGAA ATAGGCAGAT TGTGGAAAAA GGATAAATAT 
GATTGTTTAA TTTGGATCAT GACCTTCATC TTCGCCATTG TCCTTGGACT CGGATTAGGC 
CTGGCGGCAA GTGTAGCATT TCAACTCCTA ACTATTGTGT TCAGGACCCA ATTTCCAAAG 
TGCAGCACAT TGGCTAATGT TGGAAGGAGC AACATCTACA AGAATAAAAA GAATTATGCC 
GAAGTGTATG AGCCTGAAGG AGTGAAAATT TTTAGATGTC CATCTCCAAT CTACTTCGCA 
AACATTGGTT TCTTTAAGCA GAAACTTATT GATGCTGTTG GCTTTAGCCC ACTTCGAATT 
CTACGGAAGC GCAACAAAGC TTTGAAGAAA ATCCGAAAAC TGCAGAAACG AGGTCTGATA 
CAGATGACAC CTAAAGGGTT TATATGCACC TCTGACGGTT TCAAAGACTC CGACGAAGAA 
TTGGACAACA ACCAGATAGA AGAACTTGAT CAGCCGATCA ATACCACAGA TCTGCCCTTT 
GACATAGACT GGAACGGGGA TCTTCCCCTC AACATCACCA TCCCCAAAAT CAGCCTCCAC 
AGCCTCATCC TCGATTTTTC AGCAGTGTCT TTCCTTGACG TCTCCTCAAT GAGGGGCCTC 
AGAACGATTT TACAAGAATT TATTAGGATC AAGGTGGACG TATATATTGT GGGAACCGAT 
GATGATTTCA TTGACAAACT TGCTCGGTGT GAATTCTTCG ATGATGAAGT CACAGACTCA 
ATATTTTTCT TAACAATCCA TGATGCTATT TTGCATATTT TGATGAAGAA GGACTACAGC 
ACTTCAAAGT TTAATTCCAG CCAGGAAAAA GAAAGGAAAT TTGACTTTAC CATAAATACA 
AATGGAGGAC TACGTAATCG GGAATGTCAG GTACCAGTTG AAACGAAATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor necrosis factor-? acts reciprocally with solute carrier family 26, member 3, (downregulated-in-adenoma) and reduces its expression, leading to intestinal inflammation.
International journal of molecular medicine41(3)1224-1232(2018 Mar)
Ding X,Li D,Li M,Tian D,Yu H,Yu Q

SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis.
Laboratory investigation; a journal of technical methods and pathology(2018 Jan)
Ding X,Li D,Li M,Wang H,He Q,Wang Y,Yu H,Tian D,Yu Q

Activation of Nuclear Factor-?B by Tumor Necrosis Factor in Intestinal Epithelial Cells and Mouse Intestinal Epithelia Reduces Expression of the Chloride Transporter SLC26A3.
Gastroenterology153(5)1338-1350.e3(2017 Nov)
Kumar A,Chatterjee I,Gujral T,Alakkam A,Coffing H,Anbazhagan AN,Borthakur A,Saksena S,Gill RK,Alrefai WA,Dudeja PK

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Slc26a3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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