Dpm2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dpm2
Entrez Gene ID	13481
Full Name	dolichol-phosphate (beta-D) mannosyltransferase 2
Synonyms	AW557993,R75484
General protein information	Preferred Names dolichol-phosphate (beta-D) mannosyltransferase 2 Names dolichol phosphate-mannose biosynthesis regulatory protein DPM synthase subunit 2 dolichol-phosphate mannose synthase subunit 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_010073.2	NP_034203.1	dolichol phosphate-mannose biosynthesis regulatory protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DPM2	XP_003312386.1
Canis lupus familiaris (dog)	DPM2	XP_005625370.1
Gallus gallus (chicken)	DPM2	NP_001186093.1
Oryza sativa (rice)	Os02g0140101	NP_001172795.1
Xenopus tropicalis (tropical clawed frog)	dpm2	NP_001016297.1
	DPM2	XP_001093450.1
Homo sapiens (human)	DPM2	NP_003854.1
Mus musculus (house mouse)	Dpm2	NP_034203.1
Arabidopsis thaliana (thale cress)	AT1G74340	NP_177574.1
Bos taurus (cattle)	DPM2	NP_001039733.1
Rattus norvegicus (Norway rat)	Dpm2	NP_062125.1
Danio rerio (zebrafish)	dpm2	NP_001116318.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Protein-protein interaction panel using mouse full-length cDNAs.
Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S, Bono H, Okazaki Y, Hayashizaki Y
Genome research11(10)1758-65(2001 Oct)

Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2.
Watanabe R, Murakami Y, Marmor MD, Inoue N, Maeda Y, Hino J, Kangawa K, Julius M, Kinoshita T
The EMBO journal19(16)4402-11(2000 Aug)

DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.
Maeda Y, Tomita S, Watanabe R, Ohishi K, Kinoshita T
The EMBO journal17(17)4920-9(1998 Sep)

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.
Lennon G, Auffray C, Polymeropoulos M, Soares MB
Genomics33(1)151-2(1996 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dpm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dpm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14727	NM_010073.2 Latest version!	Mus musculus dolichol-phosphate (beta-D) mannosyltransferase 2 (Dpm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dpm2 ( NM_010073.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034203.1 Mus musculus dolichol-phosphate (beta-D) mannosyltransferase 2 (Dpm2), mRNA.

Price & Availability↑

CloneID	OMu14727
Clone ID Related Accession (Same CDS sequence)	NM_010073.2
Accession Version	NM_010073.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	dolichol phosphate-mannose biosynthesis regulatory protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008256.1. On Jun 10, 2003 this sequence version replaced NM_010073.1. ##Evidence-Data-START## Transcript exon combination :: BC008256.1, DV044804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCACCG GGACAGACCA AGCAGTAGGA TTTGGCCTTG TCGCCGTTAG CTTGATCATC 
TTCACCTACT ACACCACTTG GGTGATTCTC TTGCCATTCA TTGACAGCCA GCATGTCATC 
CACAAATACT TCCTGCCCCG CGCCTACGCC GTCCTCCTCC CGTTGGCCGC AGGCCTCCTG 
CTGCTCCTAT TTGTGGGATT GTTCATCACC TATGTGATGC TGAAGAGCCA GAAGATAACC 
AAGAAGGCTC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034203.1
CDS	53..307
Translation	MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPFIDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVMLKSQKITKKAQ

Target ORF information:

RefSeq Version	NM_010073.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dolichol-phosphate (beta-D) mannosyltransferase 2 (Dpm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010073.2

ORF Insert Sequence:

ATGGCCACCG GGACAGACCA AGCAGTAGGA TTTGGCCTTG TCGCCGTTAG CTTGATCATC 
TTCACCTACT ACACCACTTG GGTGATTCTC TTGCCATTCA TTGACAGCCA GCATGTCATC 
CACAAATACT TCCTGCCCCG CGCCTACGCC GTCCTCCTCC CGTTGGCCGC AGGCCTCCTG 
CTGCTCCTAT TTGTGGGATT GTTCATCACC TATGTGATGC TGAAGAGCCA GAAGATAACC 
AAGAAGGCTC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Protein-protein interaction panel using mouse full-length cDNAs.
Genome research11(10)1758-65(2001 Oct)
Suzuki H,Fukunishi Y,Kagawa I,Saito R,Oda H,Endo T,Kondo S,Bono H,Okazaki Y,Hayashizaki Y

Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2.
The EMBO journal19(16)4402-11(2000 Aug)
Watanabe R,Murakami Y,Marmor MD,Inoue N,Maeda Y,Hino J,Kangawa K,Julius M,Kinoshita T

DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.
The EMBO journal17(17)4920-9(1998 Sep)
Maeda Y,Tomita S,Watanabe R,Ohishi K,Kinoshita T

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.
Genomics33(1)151-2(1996 Apr)
Lennon G,Auffray C,Polymeropoulos M,Soares MB