Dlx4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dlx4
Entrez Gene ID	13394
Full Name	distal-less homeobox 4
Synonyms	Dlx-4,Dlx7
General protein information	Preferred Names distal-less homeobox 4 Names homeobox protein DLX-4 DII D distal-less homeo box 7 homeobox protein DLX-7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 D\|11 59.01 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007867.4	NP_031893.3	homeobox protein DLX-4
XM_030245519.1	XP_030101379.1	homeobox protein DLX-4 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DLX4	XP_511870.3
Mus musculus (house mouse)	Dlx4	NP_031893.3
Bos taurus (cattle)	DLX4	NP_001091510.1
Homo sapiens (human)	DLX4	NP_612138.1
	DLX4	XP_001095208.1
Rattus norvegicus (Norway rat)	Dlx4	NP_001100510.1

Gene Ontology
Bibliography

Related articles in PubMed

AP-2? and AP-2? cooperatively orchestrate homeobox gene expression during branchial arch patterning.
Van Otterloo E, Li H, Jones KL, Williams T
Development (Cambridge, England)(2017 Dec)

The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development.
Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A
Cell reports19(5)949-956(2017 May)

DLX4 is associated with orofacial clefting and abnormal jaw development.
Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, Gil-Da-Silva-Lopes VL, Lao R, Wan E, Tang PL, Kwok PY, Klein O, Zhuan B, Slavotinek AM
Human molecular genetics24(15)4340-52(2015 Aug)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

nuclear import of Dlx4 is compromised by specific residues that flank the nuclear localization signal
Title: Impaired nuclear import of mammalian Dlx4 proteins as a consequence of rapid sequence divergence.

Genomic structure and functional control of the Dlx3-7 bigene cluster
Title: Genomic structure and functional control of the Dlx3-7 bigene cluster.

The following Dlx4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dlx4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21452	NM_007867.4 Latest version!	Mus musculus distal-less homeobox 4 (Dlx4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu85616	XM_030245519.1 Latest version!	Mus musculus distal-less homeobox 4 (Dlx4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dlx4 ( NM_007867.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031893.3 Mus musculus distal-less homeobox 4 (Dlx4), mRNA.

Price & Availability↑

CloneID	OMu21452
Clone ID Related Accession (Same CDS sequence)	NM_007867.4
Accession Version	NM_007867.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Mus musculus(house mouse)
Product	homeobox protein DLX-4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645850.6. On Apr 8, 2008 this sequence version replaced NM_007867.3. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK145123.1, U73329.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTCTT TACCCTGTCC CCTTCCTGAC CGTGGTGCCT CCAACGTTGT CTTCCCGGAC 
CTCGCCCCCG CCCTGTCGGT AGTGGCTGCT TACCCGCTCG GACTATCCCC GGGAACCGCA 
GCTTCTCCCG ATTTGTCCTA CTCCCAGTCC TACGGCCACC CCCGGTCCTA TTCCCACCCT 
GGGCCGGCAA CCCCAGGAGA CTCCTACCTG CCCCGCCAGC AACAATTGGT GGCGCCATCT 
CAGCCCTTTC ACAGGCCGGC TGAACACCCG CAGGAGCTCG AAGCAGAATC AGAGAAGCTG 
GCACTGTCTC TGGTGCCCTC CCAGCAGCAG TCCCTGACCA GGAAGCTGCG CAAGCCCAGA 
ACCATCTACT CTAGCCTGCA GCTCCAACAC CTGAACCAGC GTTTCCAGCA CACCCAATAC 
CTGGCCCTGC CCGAGAGAGC TCAGCTGGCA GCACAACTCG GACTCACCCA AACCCAGGTA 
AAGATCTGGT TTCAGAACAA ACGCTCCAAA TATAAGAAGC TCCTGAAACA GAGCTCTGGG 
GAGCCGGAAG AGGACTTCTC TGGGAGACCC CCCTCCCTGT CTCCCCACTC TCCAGCCCTA 
CCATTCATCT GGGGTCTACC CAAGGCAGAC ACCCTGCCTT CCAGTGGCTA TGACAACAGC 
CACTTTGGTG CCTGGTATCA GCATCGCTCC CCAGATGTGC TGGCACTGCC TCAGATGATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031893.3
CDS	321..1043
Translation	MTSLPCPLPDRGASNVVFPDLAPALSVVAAYPLGLSPGTAASPDLSYSQSYGHPRSYSHPGPATPGDSYLPRQQQLVAPSQPFHRPAEHPQELEAESEKLALSLVPSQQQSLTRKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQSSGEPEEDFSGRPPSLSPHSPALPFIWGLPKADTLPSSGYDNSHFGAWYQHRSPDVLALPQMM

Target ORF information:

RefSeq Version	NM_007867.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus distal-less homeobox 4 (Dlx4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007867.4

ORF Insert Sequence:

ATGACCTCTT TACCCTGTCC CCTTCCTGAC CGTGGTGCCT CCAACGTTGT CTTCCCGGAC 
CTCGCCCCCG CCCTGTCGGT AGTGGCTGCT TACCCGCTCG GACTATCCCC GGGAACCGCA 
GCTTCTCCCG ATTTGTCCTA CTCCCAGTCC TACGGCCACC CCCGGTCCTA TTCCCACCCT 
GGGCCGGCAA CCCCAGGAGA CTCCTACCTG CCCCGCCAGC AACAATTGGT GGCGCCATCT 
CAGCCCTTTC ACAGGCCGGC TGAACACCCG CAGGAGCTCG AAGCAGAATC AGAGAAGCTG 
GCACTGTCTC TGGTGCCCTC CCAGCAGCAG TCCCTGACCA GGAAGCTGCG CAAGCCCAGA 
ACCATCTACT CTAGCCTGCA GCTCCAACAC CTGAACCAGC GTTTCCAGCA CACCCAATAC 
CTGGCCCTGC CCGAGAGAGC TCAGCTGGCA GCACAACTCG GACTCACCCA AACCCAGGTA 
AAGATCTGGT TTCAGAACAA ACGCTCCAAA TATAAGAAGC TCCTGAAACA GAGCTCTGGG 
GAGCCGGAAG AGGACTTCTC TGGGAGACCC CCCTCCCTGT CTCCCCACTC TCCAGCCCTA 
CCATTCATCT GGGGTCTACC CAAGGCAGAC ACCCTGCCTT CCAGTGGCTA TGACAACAGC 
CACTTTGGTG CCTGGTATCA GCATCGCTCC CCAGATGTGC TGGCACTGCC TCAGATGATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dlx4 ( XM_030245519.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030101379.1 Mus musculus distal-less homeobox 4 (Dlx4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu85616
Clone ID Related Accession (Same CDS sequence)	XM_030245519.1
Accession Version	XM_030245519.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	homeobox protein DLX-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTCTT TACCCTGTCC CCTTCCTGAC CGTGGTGCCT CCAACGTTGT CTTCCCGGAC 
CTCGCCCCCG CCCTGTCGGT AGTGGCTGCT TACCCGCTCG GACTATCCCC GGGAACCGCA 
GCTTCTCCCG ATTTGTCCTA CTCCCAGTCC TACGGCCACC CCCGGTCCTA TTCCCACCCT 
GGGCCGGCAA CCCCAGGAGA CTCCTACCTG CCCCGCCAGC AACAATTGGT GGCGCCATCT 
CAGCCCTTTC ACAGGCCGGC TGAACACCCG CAGGAGCTCG AAGCAGTTTT GAAAAGCCAG 
GCGGGAGGGC TCCCTACCCC ACCCCCTGGA GCAGTGGAGC TGTGTGAGTA CCTGTGTAAC 
GGAAATTTGC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030101379.1
CDS	814..1188
Translation	MTSLPCPLPDRGASNVVFPDLAPALSVVAAYPLGLSPGTAASPDLSYSQSYGHPRSYSHPGPATPGDSYLPRQQQLVAPSQPFHRPAEHPQELEAVLKSQAGGLPTPPPGAVELCEYLCNGNLP

Target ORF information:

RefSeq Version	XM_030245519.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus distal-less homeobox 4 (Dlx4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030245519.1

ORF Insert Sequence:

ATGACCTCTT TACCCTGTCC CCTTCCTGAC CGTGGTGCCT CCAACGTTGT CTTCCCGGAC 
CTCGCCCCCG CCCTGTCGGT AGTGGCTGCT TACCCGCTCG GACTATCCCC GGGAACCGCA 
GCTTCTCCCG ATTTGTCCTA CTCCCAGTCC TACGGCCACC CCCGGTCCTA TTCCCACCCT 
GGGCCGGCAA CCCCAGGAGA CTCCTACCTG CCCCGCCAGC AACAATTGGT GGCGCCATCT 
CAGCCCTTTC ACAGGCCGGC TGAACACCCG CAGGAGCTCG AAGCAGTTTT GAAAAGCCAG 
GCGGGAGGGC TCCCTACCCC ACCCCCTGGA GCAGTGGAGC TGTGTGAGTA CCTGTGTAAC 
GGAAATTTGC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

AP-2? and AP-2? cooperatively orchestrate homeobox gene expression during branchial arch patterning.
Development (Cambridge, England)(2017 Dec)
Van Otterloo E,Li H,Jones KL,Williams T

The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development.
Cell reports19(5)949-956(2017 May)
Inoue K,Hirose M,Inoue H,Hatanaka Y,Honda A,Hasegawa A,Mochida K,Ogura A

DLX4 is associated with orofacial clefting and abnormal jaw development.
Human molecular genetics24(15)4340-52(2015 Aug)
Wu D,Mandal S,Choi A,Anderson A,Prochazkova M,Perry H,Gil-Da-Silva-Lopes VL,Lao R,Wan E,Tang PL,Kwok PY,Klein O,Zhuan B,Slavotinek AM

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Dlx4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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