Defa-rs4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Defa-rs4
Entrez Gene ID	13223
Full Name	defensin, alpha,, related sequence 4
Synonyms	CRS4C-1a,CRS4C1a,Defcr-rs4
General protein information	Preferred Names defensin, alpha,, related sequence 4 Names alpha-defensin,, related sequence 4 defensin related cryptdin, related sequence 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005418.1	NP_001005418.1	alpha-defensin, related sequence 4 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Increased diversity of intestinal antimicrobial peptides by covalent dimer formation.
Hornef MW, P?tsep K, Karlsson J, Refai E, Andersson M
Nature immunology5(8)836-43(2004 Aug)

Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin.
Ouellette AJ, Darmoul D, Tran D, Huttner KM, Yuan J, Selsted ME
Infection and immunity67(12)6643-51(1999 Dec)

A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
Huttner KM, Ouellette AJ
Genomics24(1)99-109(1994 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Defa-rs4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Defa-rs4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu24827	NM_001005418.1 Latest version!	Mus musculus defensin, alpha, related sequence 4 (Defa-rs4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Defa-rs4 ( NM_001005418.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001005418.1 Mus musculus defensin, alpha, related sequence 4 (Defa-rs4), mRNA.

Price & Availability↑

CloneID	OMu24827
Clone ID Related Accession (Same CDS sequence)	NM_001005418.1
Accession Version	NM_001005418.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2013-04-16
Organism	Mus musculus(house mouse)
Product	alpha-defensin, related sequence 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ564861.1. ##Evidence-Data-START## Transcript exon combination :: AJ564861.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAGAAAC TTGTCCTCCT CTTTGCCCTT GTCCTGCTTG CATTCCAGGT CCAGGCTGAT 
TCTATCCAAA ACACAGATGA AGAGATTAAA ACTGAGGAAC AGCCAGGAGA AGAGAACCAG 
GCTGTGTCTG TCTCCTTTGG AGACCCACAA GGCTCTGCTC TTCAAGATGC AGCCGTAGGA 
TGGGGTCGGC GGTGCCCACA ATGCCCTAGA TGCCCGTCAT GCCCATCTTG CCCGAGATGC 
CCGAGGTGCC CGAGGTGCAA ATGCAATCCA AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005418.1
CDS	40..315
Translation	MKKLVLLFALVLLAFQVQADSIQNTDEEIKTEEQPGEENQAVSVSFGDPQGSALQDAAVGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK

Target ORF information:

RefSeq Version	NM_001005418.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus defensin, alpha, related sequence 4 (Defa-rs4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005418.1

ORF Insert Sequence:

ATGAAGAAAC TTGTCCTCCT CTTTGCCCTT GTCCTGCTTG CATTCCAGGT CCAGGCTGAT 
TCTATCCAAA ACACAGATGA AGAGATTAAA ACTGAGGAAC AGCCAGGAGA AGAGAACCAG 
GCTGTGTCTG TCTCCTTTGG AGACCCACAA GGCTCTGCTC TTCAAGATGC AGCCGTAGGA 
TGGGGTCGGC GGTGCCCACA ATGCCCTAGA TGCCCGTCAT GCCCATCTTG CCCGAGATGC 
CCGAGGTGCC CGAGGTGCAA ATGCAATCCA AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased diversity of intestinal antimicrobial peptides by covalent dimer formation.
Nature immunology5(8)836-43(2004 Aug)
Hornef MW,P?tsep K,Karlsson J,Refai E,Andersson M

Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin.
Infection and immunity67(12)6643-51(1999 Dec)
Ouellette AJ,Darmoul D,Tran D,Huttner KM,Yuan J,Selsted ME

A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
Genomics24(1)99-109(1994 Nov)
Huttner KM,Ouellette AJ