Crygc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crygc
Entrez Gene ID	12966
Full Name	crystallin, gamma C
Synonyms	Cryg-5
General protein information	Preferred Names crystallin, gamma C Names gamma-crystallin C gamma-C-crystallin gammaC-crystallin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 C2\|1 32.81 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082573.2	NP_001076042.1	gamma-crystallin C isoform 2
NM_007775.2	NP_031801.1	gamma-crystallin C isoform 1

Pathways from BioSystems

Homologies

	CRYGC	NP_001076433.1
Pan troglodytes (chimpanzee)	CRYGC	NP_001129133.1
Mus musculus (house mouse)	Crygc	NP_001076042.1
Homo sapiens (human)	CRYGC	NP_066269.1
Bos taurus (cattle)	CRYGC	NP_001013613.1
Rattus norvegicus (Norway rat)	Crygc	NP_264077.1
Danio rerio (zebrafish)	si:dkey-57a22.15	NP_001116783.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Correction of a genetic disease in mouse via use of CRISPR-Cas9.
Wu Y, Liang D, Wang Y, Bai M, Tang W, Bao S, Yan Z, Li D, Li J
Cell stem cell13(6)659-62(2013 Dec)

The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.
Xie Q, Cvekl A
The Journal of biological chemistry286(50)43259-71(2011 Dec)

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.
Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL
Science (New York, N.Y.)331(6024)1571-6(2011 Mar)

A 1-bp deletion in the gammaC-crystallin leads to dominant cataracts in mice.
Zhao L, Li K, Bao S, Zhou Y, Liang Y, Zhao G, Chen Y, Xiao J
Mammalian genome : official journal of the International Mammalian Genome Society21(7-8)361-9(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a 1-bp deletion in gammaC-crystallin leads to cataract.
Title: A 1-bp deletion in the gammaC-crystallin leads to dominant cataracts in mice.

presence of measurable interactions between MIP26 and all crystallins, with the extent of interactions decreasing from alphaA- and alphaB-crystallin to betaB2- and gammaC-crystallin.
Title: Confocal fluorescence microscopy study of interaction between lens MIP26/AQP0 and crystallins in living cells.

The following Crygc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crygc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02722	NM_001082573.2 Latest version!	Mus musculus crystallin, gamma C (Crygc), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu00790	NM_007775.2 Latest version!	Mus musculus crystallin, gamma C (Crygc), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crygc ( NM_001082573.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001076042.1 Mus musculus crystallin, gamma C (Crygc), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu02722
Clone ID Related Accession (Same CDS sequence)	NM_001082573.2
Accession Version	NM_001082573.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	gamma-crystallin C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ066821.1, EF426302.1 and CK627566.1. On Sep 28, 2012 this sequence version replaced NM_001082573.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. It encodes isoform 2 which has one additional amino acid compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF426302.1, CK627760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA TCACCTTCTT CGAGGACCGC AGCTTCCAGG GCCGCTGCTA TGAGTGCAGC 
AGCGACTGCC CCAACCTGCA GACCTACTTC AGCCGCTGCA ATTCTGTCCG CGTGGACAGT 
GGCTGCTGGA TGCTCTATGA GCGCCCCAAC TACCAGGGCC ACCAGTACTT CCTGAGACGT 
GGAGAGTACC CTGACTACCA GCAGTGGATG GGTTTCAGCG ACTCCATCCG CTCCTGCCGC 
CTCATCCCCC ATCAGGCAGG TTCCCACAGA ATGCGGCTGT ATGAGAAAGA AGATCACAAA 
GGTGTCATGA TGGAGCTGAG CGAGGATTGC TCCTGCATCC AGGATCGCTT CCACCTCAGT 
GAGGTGCGCT CGCTGCAAGT GCTGGAAGGC TGCTGGGTTC TCTATGAGAT GCCTAACTAC 
CGAGGCCGCC AGTATCTGCT GAGGCCTCAA GAGTACCGGC GCTTCCAGGA CTGGGGCTCT 
GTAGATGCTA AGGCGGGCTC TTTGCGGAGG GTGGTAGATT TATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076042.1
CDS	28..555
Translation	MGKITFFEDRSFQGRCYECSSDCPNLQTYFSRCNSVRVDSGCWMLYERPNYQGHQYFLRRGEYPDYQQWMGFSDSIRSCRLIPHQAGSHRMRLYEKEDHKGVMMELSEDCSCIQDRFHLSEVRSLQVLEGCWVLYEMPNYRGRQYLLRPQEYRRFQDWGSVDAKAGSLRRVVDLY

Target ORF information:

RefSeq Version	NM_001082573.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus crystallin, gamma C (Crygc), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082573.2

ORF Insert Sequence:

ATGGGGAAGA TCACCTTCTT CGAGGACCGC AGCTTCCAGG GCCGCTGCTA TGAGTGCAGC 
AGCGACTGCC CCAACCTGCA GACCTACTTC AGCCGCTGCA ATTCTGTCCG CGTGGACAGT 
GGCTGCTGGA TGCTCTATGA GCGCCCCAAC TACCAGGGCC ACCAGTACTT CCTGAGACGT 
GGAGAGTACC CTGACTACCA GCAGTGGATG GGTTTCAGCG ACTCCATCCG CTCCTGCCGC 
CTCATCCCCC ATCAGGCAGG TTCCCACAGA ATGCGGCTGT ATGAGAAAGA AGATCACAAA 
GGTGTCATGA TGGAGCTGAG CGAGGATTGC TCCTGCATCC AGGATCGCTT CCACCTCAGT 
GAGGTGCGCT CGCTGCAAGT GCTGGAAGGC TGCTGGGTTC TCTATGAGAT GCCTAACTAC 
CGAGGCCGCC AGTATCTGCT GAGGCCTCAA GAGTACCGGC GCTTCCAGGA CTGGGGCTCT 
GTAGATGCTA AGGCGGGCTC TTTGCGGAGG GTGGTAGATT TATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Crygc ( NM_007775.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031801.1 Mus musculus crystallin, gamma C (Crygc), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu00790
Clone ID Related Accession (Same CDS sequence)	NM_007775.2
Accession Version	NM_007775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	gamma-crystallin C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ066821.1, EF426301.1 and CK627566.1. On Sep 28, 2012 this sequence version replaced NM_007775.1. Transcript Variant: This variant (1) encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA452042.1, CJ066821.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA TCACCTTCTT CGAGGACCGC AGCTTCCAGG GCCGCTGCTA TGAGTGCAGC 
AGCGACTGCC CCAACCTGCA GACCTACTTC AGCCGCTGCA ATTCTGTCCG CGTGGACAGT 
GGCTGCTGGA TGCTCTATGA GCGCCCCAAC TACCAGGGCC ACCAGTACTT CCTGAGACGT 
GGAGAGTACC CTGACTACCA GCAGTGGATG GGTTTCAGCG ACTCCATCCG CTCCTGCCGC 
CTCATCCCCC ATGCAGGTTC CCACAGAATG CGGCTGTATG AGAAAGAAGA TCACAAAGGT 
GTCATGATGG AGCTGAGCGA GGATTGCTCC TGCATCCAGG ATCGCTTCCA CCTCAGTGAG 
GTGCGCTCGC TGCAAGTGCT GGAAGGCTGC TGGGTTCTCT ATGAGATGCC TAACTACCGA 
GGCCGCCAGT ATCTGCTGAG GCCTCAAGAG TACCGGCGCT TCCAGGACTG GGGCTCTGTA 
GATGCTAAGG CGGGCTCTTT GCGGAGGGTG GTAGATTTAT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031801.1
CDS	28..552
Translation	MGKITFFEDRSFQGRCYECSSDCPNLQTYFSRCNSVRVDSGCWMLYERPNYQGHQYFLRRGEYPDYQQWMGFSDSIRSCRLIPHAGSHRMRLYEKEDHKGVMMELSEDCSCIQDRFHLSEVRSLQVLEGCWVLYEMPNYRGRQYLLRPQEYRRFQDWGSVDAKAGSLRRVVDLY

Target ORF information:

RefSeq Version	NM_007775.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus crystallin, gamma C (Crygc), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007775.2

ORF Insert Sequence:

ATGGGGAAGA TCACCTTCTT CGAGGACCGC AGCTTCCAGG GCCGCTGCTA TGAGTGCAGC 
AGCGACTGCC CCAACCTGCA GACCTACTTC AGCCGCTGCA ATTCTGTCCG CGTGGACAGT 
GGCTGCTGGA TGCTCTATGA GCGCCCCAAC TACCAGGGCC ACCAGTACTT CCTGAGACGT 
GGAGAGTACC CTGACTACCA GCAGTGGATG GGTTTCAGCG ACTCCATCCG CTCCTGCCGC 
CTCATCCCCC ATGCAGGTTC CCACAGAATG CGGCTGTATG AGAAAGAAGA TCACAAAGGT 
GTCATGATGG AGCTGAGCGA GGATTGCTCC TGCATCCAGG ATCGCTTCCA CCTCAGTGAG 
GTGCGCTCGC TGCAAGTGCT GGAAGGCTGC TGGGTTCTCT ATGAGATGCC TAACTACCGA 
GGCCGCCAGT ATCTGCTGAG GCCTCAAGAG TACCGGCGCT TCCAGGACTG GGGCTCTGTA 
GATGCTAAGG CGGGCTCTTT GCGGAGGGTG GTAGATTTAT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Correction of a genetic disease in mouse via use of CRISPR-Cas9.
Cell stem cell13(6)659-62(2013 Dec)
Wu Y,Liang D,Wang Y,Bai M,Tang W,Bao S,Yan Z,Li D,Li J

The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.
The Journal of biological chemistry286(50)43259-71(2011 Dec)
Xie Q,Cvekl A

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.
Science (New York, N.Y.)331(6024)1571-6(2011 Mar)
Lachke SA,Alkuraya FS,Kneeland SC,Ohn T,Aboukhalil A,Howell GR,Saadi I,Cavallesco R,Yue Y,Tsai AC,Nair KS,Cosma MI,Smith RS,Hodges E,Alfadhli SM,Al-Hajeri A,Shamseldin HE,Behbehani A,Hannon GJ,Bulyk ML,Drack AV,Anderson PJ,John SW,Maas RL

A 1-bp deletion in the gammaC-crystallin leads to dominant cataracts in mice.
Mammalian genome : official journal of the International Mammalian Genome Society21(7-8)361-9(2010 Aug)
Zhao L,Li K,Bao S,Zhou Y,Liang Y,Zhao G,Chen Y,Xiao J

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Crygc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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