Hapln1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hapln1
Entrez Gene ID	12950
Full Name	hyaluronan and proteoglycan link protein 1
Synonyms	BB099155,CLP,Crtl1,Crtl1l,LP,LP-1
General protein information	Preferred Names hyaluronan and proteoglycan link protein 1 Names hyaluronan and proteoglycan link protein 1 cartilage link protein 1 cartilage-link protein cartilage-linking protein 1 link protein proteoglycan link protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 C3\|13 45.5 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006517075.3	XP_006517138.1	hyaluronan and proteoglycan link protein 1 isoform X1
XM_006517075.4	XP_006517138.1	hyaluronan and proteoglycan link protein 1 isoform X1
NM_013500.4	NP_038528.3	hyaluronan and proteoglycan link protein 1 precursor

Pathways from BioSystems

Homologies

	HAPLN1	XP_001112341.1
Rattus norvegicus (Norway rat)	Hapln1	NP_062062.2
Gallus gallus (chicken)	HAPLN1	NP_990813.1
Danio rerio (zebrafish)	hapln1b	XP_002663704.3
Pan troglodytes (chimpanzee)	HAPLN1	XP_001147083.1
Mus musculus (house mouse)	Hapln1	NP_038528.3
Canis lupus familiaris (dog)	HAPLN1	XP_849484.1
Xenopus tropicalis (tropical clawed frog)	hapln1	XP_002933976.2
Homo sapiens (human)	HAPLN1	NP_001875.1
Bos taurus (cattle)	HAPLN1	NP_776713.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.
Liu G, Cooley MA, Jarnicki AG, Hsu AC, Nair PM, Haw TJ, Fricker M, Gellatly SL, Kim RY, Inman MD, Tjin G, Wark PA, Walker MM, Horvat JC, Oliver BG, Argraves WS, Knight DA, Burgess JK, Hansbro PM
JCI insight1(9)(2016 Jun)

The neuronal extracellular matrix restricts distribution and internalization of aggregated Tau-protein.
Suttkus A, Holzer M, Morawski M, Arendt T
Neuroscience313225-35(2016 Jan)

Characterization and chromosome location of the mouse link protein gene (Crtl1).
De?k F, M?t?s L, Krysan K, Liu Z, Szab? PE, Mann JR, Beier DR, Kiss I
Cytogenetics and cell genetics87(1-2)75-9(1999)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Aggrecan, link protein and TN-R were identified to be essential for the neuroprotective properties of the perineuronal net.
Title: Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress.

Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.
Title: Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.

our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS
Title: Animals lacking link protein have attenuated perineuronal nets and persistent plasticity.

reduced versican expression may contribute to a subset of the cardiac abnormalities observed in the Crtl1(-/-) mouse.
Title: Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development.

Data suggest that the reported temporal co-expression of cartilage link protein and neurocan in developing brain implicates the possibility of a cooperative function of these molecules.
Title: Cartilage link protein interacts with neurocan, which shows hyaluronan binding characteristics different from CD44 and TSG-6.

The following Hapln1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hapln1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09496	NM_013500.4 Latest version!	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu48654	XM_006517075.4 Latest version!	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu48654	XM_006517075.3	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hapln1 ( NM_013500.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038528.3 Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), mRNA.

Price & Availability↑

CloneID	OMu09496
Clone ID Related Accession (Same CDS sequence)	NM_013500.4
Accession Version	NM_013500.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	hyaluronan and proteoglycan link protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK032750.1 and AC154460.2. On Dec 8, 2007 this sequence version replaced NM_013500.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066853.1, AK032750.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGCAGA AAATGGCCCC 
CGTCTACTTG TGGAAGCAGA ACAAGCCAAG GTCTTCTCTC ACCGAGGTGG CAACGTGACA 
CTGCCATGCA AATTTTATCG AGACCCTACA GCATTTGGCT CAGGAATCCA CAAAATCCGC 
ATCAAGTGGA CCAAGCTAAC TTCAGATTAC CTCAGGGAAG TAGATGTCTT CGTTTCCATG 
GGCTATCACA AGAAGACCTA TGGAGGCTAT CAAGGTCGAG TGTTTCTGAA GGGAGGCAGT 
GATAATGATG CCTCCCTGGT CATCACGGAT CTTACCCTGG AGGATTATGG GAGATATAAA 
TGTGAGGTGA TTGAAGGGCT AGAAGATGAT ACTGCTGTGG TGGCATTGGA GTTACAAGGT 
GTGGTGTTCC CTTACTTTCC ACGACTGGGA CGCTACAATC TTAACTTTCA CGAGGCACGC 
CAGGCTTGTC TGGACCAGGA CGCAGTGATT GCTTCCTTTG ACCAGCTGTA CGATGCCTGG 
CGGGGTGGGC TGGACTGGTG CAATGCTGGC TGGCTCAGTG ATGGATCTGT GCAGTACCCA 
ATCACCAAAC CACGAGAGCC CTGCGGGGGC CAAAACACGG TGCCTGGAGT CAGGAACTAC 
GGGTTTTGGG ACAAGGATAA AAGCAGATAT GACGTTTTCT GTTTTACATC CAACTTCAAC 
GGCCGATTTT ACTACCTGAT CCACCCCACC AAACTCACCT ACGATGAGGC GGTGCAAGCT 
TGTCTCAATG ACGGTGCTCA GATCGCGAAA GTGGGCCAGA TATTTGCTGC CTGGAAGCTT 
CTGGGCTATG ACCGCTGCGA TGCCGGCTGG CTAGCGGATG GCAGCGTCCG CTATCCTATT 
TCTCGACCAA GAAGGCGCTG CAGTCCGACT GAGGCTGCAG TGCGCTTTGT AGGTTTCCCA 
GATAAAAAGC ATAAGCTATA CGGGGTCTAT TGCTTCAGAG CATACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038528.3
CDS	302..1372
Translation	MRSLLLLVLISVCWADHHLSDSYTPPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN

Target ORF information:

RefSeq Version	NM_013500.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013500.4

ORF Insert Sequence:

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGCAGA AAATGGCCCC 
CGTCTACTTG TGGAAGCAGA ACAAGCCAAG GTCTTCTCTC ACCGAGGTGG CAACGTGACA 
CTGCCATGCA AATTTTATCG AGACCCTACA GCATTTGGCT CAGGAATCCA CAAAATCCGC 
ATCAAGTGGA CCAAGCTAAC TTCAGATTAC CTCAGGGAAG TAGATGTCTT CGTTTCCATG 
GGCTATCACA AGAAGACCTA TGGAGGCTAT CAAGGTCGAG TGTTTCTGAA GGGAGGCAGT 
GATAATGATG CCTCCCTGGT CATCACGGAT CTTACCCTGG AGGATTATGG GAGATATAAA 
TGTGAGGTGA TTGAAGGGCT AGAAGATGAT ACTGCTGTGG TGGCATTGGA GTTACAAGGT 
GTGGTGTTCC CTTACTTTCC ACGACTGGGA CGCTACAATC TTAACTTTCA CGAGGCACGC 
CAGGCTTGTC TGGACCAGGA CGCAGTGATT GCTTCCTTTG ACCAGCTGTA CGATGCCTGG 
CGGGGTGGGC TGGACTGGTG CAATGCTGGC TGGCTCAGTG ATGGATCTGT GCAGTACCCA 
ATCACCAAAC CACGAGAGCC CTGCGGGGGC CAAAACACGG TGCCTGGAGT CAGGAACTAC 
GGGTTTTGGG ACAAGGATAA AAGCAGATAT GACGTTTTCT GTTTTACATC CAACTTCAAC 
GGCCGATTTT ACTACCTGAT CCACCCCACC AAACTCACCT ACGATGAGGC GGTGCAAGCT 
TGTCTCAATG ACGGTGCTCA GATCGCGAAA GTGGGCCAGA TATTTGCTGC CTGGAAGCTT 
CTGGGCTATG ACCGCTGCGA TGCCGGCTGG CTAGCGGATG GCAGCGTCCG CTATCCTATT 
TCTCGACCAA GAAGGCGCTG CAGTCCGACT GAGGCTGCAG TGCGCTTTGT AGGTTTCCCA 
GATAAAAAGC ATAAGCTATA CGGGGTCTAT TGCTTCAGAG CATACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hapln1 ( XM_006517075.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517138.1 Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu48654
Clone ID Related Accession (Same CDS sequence)	XM_006517075.3 , XM_006517075.4
Accession Version	XM_006517075.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	hyaluronan and proteoglycan link protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517075.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGAAAA TGGCCCCCGT 
CTACTTGTGG AAGCAGAACA AGCCAAGGTC TTCTCTCACC GAGGTGGCAA CGTGACACTG 
CCATGCAAAT TTTATCGAGA CCCTACAGCA TTTGGCTCAG GAATCCACAA AATCCGCATC 
AAGTGGACCA AGCTAACTTC AGATTACCTC AGGGAAGTAG ATGTCTTCGT TTCCATGGGC 
TATCACAAGA AGACCTATGG AGGCTATCAA GGTCGAGTGT TTCTGAAGGG AGGCAGTGAT 
AATGATGCCT CCCTGGTCAT CACGGATCTT ACCCTGGAGG ATTATGGGAG ATATAAATGT 
GAGGTGATTG AAGGGCTAGA AGATGATACT GCTGTGGTGG CATTGGAGTT ACAAGGTGTG 
GTGTTCCCTT ACTTTCCACG ACTGGGACGC TACAATCTTA ACTTTCACGA GGCACGCCAG 
GCTTGTCTGG ACCAGGACGC AGTGATTGCT TCCTTTGACC AGCTGTACGA TGCCTGGCGG 
GGTGGGCTGG ACTGGTGCAA TGCTGGCTGG CTCAGTGATG GATCTGTGCA GTACCCAATC 
ACCAAACCAC GAGAGCCCTG CGGGGGCCAA AACACGGTGC CTGGAGTCAG GAACTACGGG 
TTTTGGGACA AGGATAAAAG CAGATATGAC GTTTTCTGTT TTACATCCAA CTTCAACGGC 
CGATTTTACT ACCTGATCCA CCCCACCAAA CTCACCTACG ATGAGGCGGT GCAAGCTTGT 
CTCAATGACG GTGCTCAGAT CGCGAAAGTG GGCCAGATAT TTGCTGCCTG GAAGCTTCTG 
GGCTATGACC GCTGCGATGC CGGCTGGCTA GCGGATGGCA GCGTCCGCTA TCCTATTTCT 
CGACCAAGAA GGCGCTGCAG TCCGACTGAG GCTGCAGTGC GCTTTGTAGG TTTCCCAGAT 
AAAAAGCATA AGCTATACGG GGTCTATTGC TTCAGAGCAT ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517138.1
CDS	410..1477
Translation	MRSLLLLVLISVCWADHHLSDSYTPPDQDRVIHIQENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN

Target ORF information:

RefSeq Version	XM_006517075.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517075.3

ORF Insert Sequence:

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGAAAA TGGCCCCCGT 
CTACTTGTGG AAGCAGAACA AGCCAAGGTC TTCTCTCACC GAGGTGGCAA CGTGACACTG 
CCATGCAAAT TTTATCGAGA CCCTACAGCA TTTGGCTCAG GAATCCACAA AATCCGCATC 
AAGTGGACCA AGCTAACTTC AGATTACCTC AGGGAAGTAG ATGTCTTCGT TTCCATGGGC 
TATCACAAGA AGACCTATGG AGGCTATCAA GGTCGAGTGT TTCTGAAGGG AGGCAGTGAT 
AATGATGCCT CCCTGGTCAT CACGGATCTT ACCCTGGAGG ATTATGGGAG ATATAAATGT 
GAGGTGATTG AAGGGCTAGA AGATGATACT GCTGTGGTGG CATTGGAGTT ACAAGGTGTG 
GTGTTCCCTT ACTTTCCACG ACTGGGACGC TACAATCTTA ACTTTCACGA GGCACGCCAG 
GCTTGTCTGG ACCAGGACGC AGTGATTGCT TCCTTTGACC AGCTGTACGA TGCCTGGCGG 
GGTGGGCTGG ACTGGTGCAA TGCTGGCTGG CTCAGTGATG GATCTGTGCA GTACCCAATC 
ACCAAACCAC GAGAGCCCTG CGGGGGCCAA AACACGGTGC CTGGAGTCAG GAACTACGGG 
TTTTGGGACA AGGATAAAAG CAGATATGAC GTTTTCTGTT TTACATCCAA CTTCAACGGC 
CGATTTTACT ACCTGATCCA CCCCACCAAA CTCACCTACG ATGAGGCGGT GCAAGCTTGT 
CTCAATGACG GTGCTCAGAT CGCGAAAGTG GGCCAGATAT TTGCTGCCTG GAAGCTTCTG 
GGCTATGACC GCTGCGATGC CGGCTGGCTA GCGGATGGCA GCGTCCGCTA TCCTATTTCT 
CGACCAAGAA GGCGCTGCAG TCCGACTGAG GCTGCAGTGC GCTTTGTAGG TTTCCCAGAT 
AAAAAGCATA AGCTATACGG GGTCTATTGC TTCAGAGCAT ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hapln1 ( XM_006517075.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517138.1 Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu48654
Clone ID Related Accession (Same CDS sequence)	XM_006517075.3 , XM_006517075.4
Accession Version	XM_006517075.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	hyaluronan and proteoglycan link protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517075.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGAAAA TGGCCCCCGT 
CTACTTGTGG AAGCAGAACA AGCCAAGGTC TTCTCTCACC GAGGTGGCAA CGTGACACTG 
CCATGCAAAT TTTATCGAGA CCCTACAGCA TTTGGCTCAG GAATCCACAA AATCCGCATC 
AAGTGGACCA AGCTAACTTC AGATTACCTC AGGGAAGTAG ATGTCTTCGT TTCCATGGGC 
TATCACAAGA AGACCTATGG AGGCTATCAA GGTCGAGTGT TTCTGAAGGG AGGCAGTGAT 
AATGATGCCT CCCTGGTCAT CACGGATCTT ACCCTGGAGG ATTATGGGAG ATATAAATGT 
GAGGTGATTG AAGGGCTAGA AGATGATACT GCTGTGGTGG CATTGGAGTT ACAAGGTGTG 
GTGTTCCCTT ACTTTCCACG ACTGGGACGC TACAATCTTA ACTTTCACGA GGCACGCCAG 
GCTTGTCTGG ACCAGGACGC AGTGATTGCT TCCTTTGACC AGCTGTACGA TGCCTGGCGG 
GGTGGGCTGG ACTGGTGCAA TGCTGGCTGG CTCAGTGATG GATCTGTGCA GTACCCAATC 
ACCAAACCAC GAGAGCCCTG CGGGGGCCAA AACACGGTGC CTGGAGTCAG GAACTACGGG 
TTTTGGGACA AGGATAAAAG CAGATATGAC GTTTTCTGTT TTACATCCAA CTTCAACGGC 
CGATTTTACT ACCTGATCCA CCCCACCAAA CTCACCTACG ATGAGGCGGT GCAAGCTTGT 
CTCAATGACG GTGCTCAGAT CGCGAAAGTG GGCCAGATAT TTGCTGCCTG GAAGCTTCTG 
GGCTATGACC GCTGCGATGC CGGCTGGCTA GCGGATGGCA GCGTCCGCTA TCCTATTTCT 
CGACCAAGAA GGCGCTGCAG TCCGACTGAG GCTGCAGTGC GCTTTGTAGG TTTCCCAGAT 
AAAAAGCATA AGCTATACGG GGTCTATTGC TTCAGAGCAT ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517138.1
CDS	409..1476
Translation	MRSLLLLVLISVCWADHHLSDSYTPPDQDRVIHIQENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN

Target ORF information:

RefSeq Version	XM_006517075.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus hyaluronan and proteoglycan link protein 1 (Hapln1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517075.4

ORF Insert Sequence:

ATGAGAAGTC TGCTTCTCCT GGTGCTGATT TCAGTCTGTT GGGCTGACCA CCACCTTTCA 
GACAGCTACA CTCCTCCAGA TCAAGACAGA GTTATTCACA TCCAAGAAAA TGGCCCCCGT 
CTACTTGTGG AAGCAGAACA AGCCAAGGTC TTCTCTCACC GAGGTGGCAA CGTGACACTG 
CCATGCAAAT TTTATCGAGA CCCTACAGCA TTTGGCTCAG GAATCCACAA AATCCGCATC 
AAGTGGACCA AGCTAACTTC AGATTACCTC AGGGAAGTAG ATGTCTTCGT TTCCATGGGC 
TATCACAAGA AGACCTATGG AGGCTATCAA GGTCGAGTGT TTCTGAAGGG AGGCAGTGAT 
AATGATGCCT CCCTGGTCAT CACGGATCTT ACCCTGGAGG ATTATGGGAG ATATAAATGT 
GAGGTGATTG AAGGGCTAGA AGATGATACT GCTGTGGTGG CATTGGAGTT ACAAGGTGTG 
GTGTTCCCTT ACTTTCCACG ACTGGGACGC TACAATCTTA ACTTTCACGA GGCACGCCAG 
GCTTGTCTGG ACCAGGACGC AGTGATTGCT TCCTTTGACC AGCTGTACGA TGCCTGGCGG 
GGTGGGCTGG ACTGGTGCAA TGCTGGCTGG CTCAGTGATG GATCTGTGCA GTACCCAATC 
ACCAAACCAC GAGAGCCCTG CGGGGGCCAA AACACGGTGC CTGGAGTCAG GAACTACGGG 
TTTTGGGACA AGGATAAAAG CAGATATGAC GTTTTCTGTT TTACATCCAA CTTCAACGGC 
CGATTTTACT ACCTGATCCA CCCCACCAAA CTCACCTACG ATGAGGCGGT GCAAGCTTGT 
CTCAATGACG GTGCTCAGAT CGCGAAAGTG GGCCAGATAT TTGCTGCCTG GAAGCTTCTG 
GGCTATGACC GCTGCGATGC CGGCTGGCTA GCGGATGGCA GCGTCCGCTA TCCTATTTCT 
CGACCAAGAA GGCGCTGCAG TCCGACTGAG GCTGCAGTGC GCTTTGTAGG TTTCCCAGAT 
AAAAAGCATA AGCTATACGG GGTCTATTGC TTCAGAGCAT ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
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Hapln1 cDNA ORF clone, Mus musculus(house mouse)

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