Coq7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Coq7
Entrez Gene ID	12850
Full Name	demethyl-Q 7
Synonyms	clk-1
General protein information	Preferred Names demethyl-Q 7 Names 5-demethoxyubiquinone hydroxylase, mitochondrial DMQ hydroxylase coenzyme Q biosynthesis protein 7 homolog timing protein clk-1 homolog ubiquinone biosynthesis monooxygenase COQ7 ubiquinone biosynthesis protein COQ7 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 F1\|7 63.44 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_030242060.1	XP_030097920.1	5-demethoxyubiquinone hydroxylase, mitochondrial isoform X1
NM_009940.3	NP_034070.1	5-demethoxyubiquinone hydroxylase, mitochondrial isoform 1
NM_001304758.1	NP_001291687.1	5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	COQ7	NP_057222.2
Pan troglodytes (chimpanzee)	COQ7	XP_001153055.1
Kluyveromyces lactis	KLLA0E02421g	XP_454057.1
Magnaporthe oryzae (rice blast fungus)	MGG_00959	XP_003717991.1
Neurospora crassa	NCU03957	XP_957596.1
Bos taurus (cattle)	COQ7	NP_001106712.1
Eremothecium gossypii	AGOS_ACL162C	NP_983242.1
	LOC716130	XP_001114193.1
Canis lupus familiaris (dog)	COQ7	XP_536955.2
Mus musculus (house mouse)	Coq7	NP_034070.1
Caenorhabditis elegans (roundworm)	clk-1	NP_498128.1
Saccharomyces cerevisiae (baker's yeast)	CAT5	NP_014768.2
Schizosaccharomyces pombe (fission yeast)	coq7	NP_595416.1
Xenopus tropicalis (tropical clawed frog)	coq7	NP_001016068.2
	COQ7	XP_001083388.1
Rattus norvegicus (Norway rat)	Coq7	NP_036917.2
Gallus gallus (chicken)	COQ7	NP_001264101.1
Danio rerio (zebrafish)	coq7	NP_001076480.1
Drosophila melanogaster (fruit fly)	COQ7	NP_651967.2

Gene Ontology
Bibliography

Related articles in PubMed

Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death.
Yan Q, Han C, Wang G, Waddington JL, Zheng L, Zhen X
Molecular pharmacology92(6)640-652(2017 Dec)

Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis.
Wang Y, Oxer D, Hekimi S
Nature communications66393(2015 Mar)

Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolism.
Lapointe J, Hughes BG, Bigras E, Hekimi S
Physiological reports2(11)(2014 11)

Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-S?nchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, Wrobel RL, Everett JK, Mitchell JC, L?pez LC, Coon JJ, Tong L, Pagliarini DJ
Proceedings of the National Academy of Sciences of the United States of America111(44)E4697-705(2014 Nov)

Mitochondrial respiration without ubiquinone biosynthesis.
Wang Y, Hekimi S
Human molecular genetics22(23)4768-83(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clk1 plays a direct role in dopaminergic neuronal survival via regulating the autophagy-lysosome pathway that may contribute to the pathologic development of Parkinson disease.
Title: Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death.

Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Title: Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

These findings indicate that MCLK1 (also known as Coq7) regulates both coenzyme Q synthesis and distribution within mitochondrial membranes.
Title: The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice.

An enhanced immune response of Mclk1+/- mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging
Title: An enhanced immune response of Mclk1?/? mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging.

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues
Title: Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.

The following Coq7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Coq7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05183	NM_009940.3 Latest version!	Mus musculus demethyl-Q 7 (Coq7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu67436	NM_001304758.1 Latest version!	Mus musculus demethyl-Q 7 (Coq7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu89337	XM_030242060.1 Latest version!	Mus musculus demethyl-Q 7 (Coq7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Coq7 ( NM_009940.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034070.1 Mus musculus demethyl-Q 7 (Coq7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05183
Clone ID Related Accession (Same CDS sequence)	NM_009940.3
Accession Version	NM_009940.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	5-demethoxyubiquinone hydroxylase, mitochondrial isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY284216.1 and BC038681.1. On Feb 11, 2015 this sequence version replaced NM_009940.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038681.1, BF532230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGCCG CCGGAGCCAT AGCGGCTGCT TCCGTGGGAC GCCTGCGCAC TGGTGTCCGG 
AGGCCCTTCT CAGAGTATGG AAGAGGCCTC ATCATCAGGT GTCACAGTTC GGGGATGACC 
TTAGACAATA TTAACCGGGC AGCCGTGGAT CGAATAATTC GGGTGGATCA CGCTGGTGAA 
TATGGAGCAA ACCGCATCTA TGCAGGGCAA ATGGCCGTGC TCGGTCGGAC CAGTGTTGGC 
CCTGTCATTC AGAAAATGTG GGATCAAGAG AAGAACCATT TGAAAAAGTT CAACGAGTTG 
ATGATTGCAT TCAGGGTCCG ACCTACGGTT TTGATGCCCT TGTGGAACGT GGCAGGCTTT 
GCCCTGGGGG CAGGAACTGC CTTGCTGGGG AAGGAAGGAG CAATGGCCTG CACCGTGGCG 
GTAGAAGAGT CTATCGCTAA TCACTACAAC AACCAGATCC GCATGCTGAT GGAAGAGGAC 
CCTGAGAAGT ATGAGGAGCT GCTGCAGGTC ATCAAGCAGT TTCGCGATGA GGAGCTTGAA 
CACCACGATA CAGGCCTGGA CCATGACGCA GAGCTGGCTC CCGCGTATGC CTTGTTGAAG 
AGGATTATCC AGGCCGGATG CAGTGCAGCC ATATATTTAT CAGAAAGGTT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034070.1
CDS	106..759
Translation	MSAAGAIAAASVGRLRTGVRRPFSEYGRGLIIRCHSSGMTLDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMIAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIANHYNNQIRMLMEEDPEKYEELLQVIKQFRDEELEHHDTGLDHDAELAPAYALLKRIIQAGCSAAIYLSERF

Target ORF information:

RefSeq Version	NM_009940.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus demethyl-Q 7 (Coq7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009940.3

ORF Insert Sequence:

ATGAGCGCCG CCGGAGCCAT AGCGGCTGCT TCCGTGGGAC GCCTGCGCAC TGGTGTCCGG 
AGGCCCTTCT CAGAGTATGG AAGAGGCCTC ATCATCAGGT GTCACAGTTC GGGGATGACC 
TTAGACAATA TTAACCGGGC AGCCGTGGAT CGAATAATTC GGGTGGATCA CGCTGGTGAA 
TATGGAGCAA ACCGCATCTA TGCAGGGCAA ATGGCCGTGC TCGGTCGGAC CAGTGTTGGC 
CCTGTCATTC AGAAAATGTG GGATCAAGAG AAGAACCATT TGAAAAAGTT CAACGAGTTG 
ATGATTGCAT TCAGGGTCCG ACCTACGGTT TTGATGCCCT TGTGGAACGT GGCAGGCTTT 
GCCCTGGGGG CAGGAACTGC CTTGCTGGGG AAGGAAGGAG CAATGGCCTG CACCGTGGCG 
GTAGAAGAGT CTATCGCTAA TCACTACAAC AACCAGATCC GCATGCTGAT GGAAGAGGAC 
CCTGAGAAGT ATGAGGAGCT GCTGCAGGTC ATCAAGCAGT TTCGCGATGA GGAGCTTGAA 
CACCACGATA CAGGCCTGGA CCATGACGCA GAGCTGGCTC CCGCGTATGC CTTGTTGAAG 
AGGATTATCC AGGCCGGATG CAGTGCAGCC ATATATTTAT CAGAAAGGTT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Coq7 ( NM_001304758.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001291687.1 Mus musculus demethyl-Q 7 (Coq7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu67436
Clone ID Related Accession (Same CDS sequence)	NM_001304758.1
Accession Version	NM_001304758.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY284216.1 and AK158380.1. On Feb 15, 2015 this sequence version replaced XM_006507296.2. Transcript Variant: This variant (2) contains two alternate exons including an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is longer and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158380.1 [ECO:0000332] ##Evidence-Data-END##

ATGAGCGCCG CCGGAGCCAT AGCGGCTGCT TCCGTGGGAC GCCTGCGCAC TGGTGTCCGG 
AGGCCCTTCT CAGAGTATGG AAGAGGCCTC ATCATCAGGT GTCACAGTTC GGGGATGACC 
TTAGACAATA TTAACCGGGC AGCCGTGGAT CGAATAATTC GGGTGGATCA CGCTGGTGAA 
TATGGAGCAA ACCGCATCTA TGCAGGGCAA ATGGCCGTGC TCGGTCGGAC CAGTGTTGGC 
CCTGTCATTC AGAAAATGTG GGATCAAGAG AAGAACCATT TGAAAAAGTT CAACGAGTTG 
ATGATTGCAT TCAGGGTCCG ACCTACGGTT TTGATGCCCT TGTGGAACGT GGCAGGCTTT 
GCCCTGGGGG CAGGAACTGC CTTGCTGGGG AAGGAAGGAG CAATGGCCTG CACCGTGGCG 
GTAGAAGAGT CTATCGCTAA TCACTACAAC AACCAGATCC GCATGCTGAT GGAAGAGGAC 
CCTGAGAAGT ATGAGGAGCT GCTGCAGGTC ATCAAGCAGT TTCGCGATGA GGAGCTTGAA 
CACCACGATA CAGGCCTGGA CCATGACGCA GAGCTGCCCT TTCAGTGCCT CAACAGCTGG 
AAACACATTC CAAGCTATAT GTCTTCACCG GGCAGGGACA ATGATCATGA AAAAAAAAGT 
CATCAAAACA CAAAGTGGAG AACCTGGGAA ACAGCAATGT GCAGGGTGAT GAGGGAGGCG 
TGGGTTCAAA TCCCAGCTTT ACCACTGCAG GCTATAGGAT CCCAGGCAGT GAACATAGCC 
TGCCTGGGCC TCAGTGTTCC CACCTGCAAA GTAGAGATGA AGACAGAAGC TGCTTTGAAG 
ATTGTTCTGC ATGGGAGGGA TGAACAAGCC CCACATCGTG AGGGACCGAG GACTGCCACT 
GAAGAACTGT TCTGGCTGGC TTCCATCTCT CTCCACAATG CTGCCAACAG ACAGGGAAGA 
GGGGTCTTAT ATCTGGCATG CTCGCTTTGC AAACTTTGTG CACAATGGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291687.1
CDS	106..1119
Translation	MSAAGAIAAASVGRLRTGVRRPFSEYGRGLIIRCHSSGMTLDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMIAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIANHYNNQIRMLMEEDPEKYEELLQVIKQFRDEELEHHDTGLDHDAELPFQCLNSWKHIPSYMSSPGRDNDHEKKSHQNTKWRTWETAMCRVMREAWVQIPALPLQAIGSQAVNIACLGLSVPTCKVEMKTEAALKIVLHGRDEQAPHREGPRTATEELFWLASISLHNAANRQGRGVLYLACSLCKLCAQWL

Target ORF information:

RefSeq Version	NM_001304758.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus demethyl-Q 7 (Coq7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304758.1

ORF Insert Sequence:

ATGAGCGCCG CCGGAGCCAT AGCGGCTGCT TCCGTGGGAC GCCTGCGCAC TGGTGTCCGG 
AGGCCCTTCT CAGAGTATGG AAGAGGCCTC ATCATCAGGT GTCACAGTTC GGGGATGACC 
TTAGACAATA TTAACCGGGC AGCCGTGGAT CGAATAATTC GGGTGGATCA CGCTGGTGAA 
TATGGAGCAA ACCGCATCTA TGCAGGGCAA ATGGCCGTGC TCGGTCGGAC CAGTGTTGGC 
CCTGTCATTC AGAAAATGTG GGATCAAGAG AAGAACCATT TGAAAAAGTT CAACGAGTTG 
ATGATTGCAT TCAGGGTCCG ACCTACGGTT TTGATGCCCT TGTGGAACGT GGCAGGCTTT 
GCCCTGGGGG CAGGAACTGC CTTGCTGGGG AAGGAAGGAG CAATGGCCTG CACCGTGGCG 
GTAGAAGAGT CTATCGCTAA TCACTACAAC AACCAGATCC GCATGCTGAT GGAAGAGGAC 
CCTGAGAAGT ATGAGGAGCT GCTGCAGGTC ATCAAGCAGT TTCGCGATGA GGAGCTTGAA 
CACCACGATA CAGGCCTGGA CCATGACGCA GAGCTGCCCT TTCAGTGCCT CAACAGCTGG 
AAACACATTC CAAGCTATAT GTCTTCACCG GGCAGGGACA ATGATCATGA AAAAAAAAGT 
CATCAAAACA CAAAGTGGAG AACCTGGGAA ACAGCAATGT GCAGGGTGAT GAGGGAGGCG 
TGGGTTCAAA TCCCAGCTTT ACCACTGCAG GCTATAGGAT CCCAGGCAGT GAACATAGCC 
TGCCTGGGCC TCAGTGTTCC CACCTGCAAA GTAGAGATGA AGACAGAAGC TGCTTTGAAG 
ATTGTTCTGC ATGGGAGGGA TGAACAAGCC CCACATCGTG AGGGACCGAG GACTGCCACT 
GAAGAACTGT TCTGGCTGGC TTCCATCTCT CTCCACAATG CTGCCAACAG ACAGGGAAGA 
GGGGTCTTAT ATCTGGCATG CTCGCTTTGC AAACTTTGTG CACAATGGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Coq7 ( XM_030242060.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030097920.1 Mus musculus demethyl-Q 7 (Coq7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu89337
Clone ID Related Accession (Same CDS sequence)	XM_030242060.1
Accession Version	XM_030242060.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	5-demethoxyubiquinone hydroxylase, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTTAG ACAATATTAA CCGGGCAGCC GTGGATCGAA TAATTCGGGT GGATCACGCT 
GGTGAATATG GAGCAAACCG CATCTATGCA GGGCAAATGG CCGTGCTCGG TCGGACCAGT 
GTTGGCCCTG TCATTCAGAA AATGTGGGAT CAAGAGAAGA ACCATTTGAA AAAGTTCAAC 
GAGTTGATGA TTGCATTCAG GGTCCGACCT ACGGTTTTGA TGCCCTTGTG GAACGTGGCA 
GGCTTTGCCC TGGGGGCAGG AACTGCCTTG CTGGGGAAGG AAGGAGCAAT GGCCTGCACC 
GTGGCGGTAG AAGAGTCTAT CGCTAATCAC TACAACAACC AGATCCGCAT GCTGATGGAA 
GAGGACCCTG AGAAGTATGA GGAGCTGCTG CAGGTCATCA AGCAGTTTCG CGATGAGGAG 
CTTGAACACC ACGATACAGG CCTGGACCAT GACGCAGAGC TGGCTCCCGC GTATGCCTTG 
TTGAAGAGGA TTATCCAGGC CGGATGCAGT GCAGCCATAT ATTTATCAGA AAGGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030097920.1
CDS	197..736
Translation	MTLDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMIAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIANHYNNQIRMLMEEDPEKYEELLQVIKQFRDEELEHHDTGLDHDAELAPAYALLKRIIQAGCSAAIYLSERF

Target ORF information:

RefSeq Version	XM_030242060.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus demethyl-Q 7 (Coq7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030242060.1

ORF Insert Sequence:

ATGACCTTAG ACAATATTAA CCGGGCAGCC GTGGATCGAA TAATTCGGGT GGATCACGCT 
GGTGAATATG GAGCAAACCG CATCTATGCA GGGCAAATGG CCGTGCTCGG TCGGACCAGT 
GTTGGCCCTG TCATTCAGAA AATGTGGGAT CAAGAGAAGA ACCATTTGAA AAAGTTCAAC 
GAGTTGATGA TTGCATTCAG GGTCCGACCT ACGGTTTTGA TGCCCTTGTG GAACGTGGCA 
GGCTTTGCCC TGGGGGCAGG AACTGCCTTG CTGGGGAAGG AAGGAGCAAT GGCCTGCACC 
GTGGCGGTAG AAGAGTCTAT CGCTAATCAC TACAACAACC AGATCCGCAT GCTGATGGAA 
GAGGACCCTG AGAAGTATGA GGAGCTGCTG CAGGTCATCA AGCAGTTTCG CGATGAGGAG 
CTTGAACACC ACGATACAGG CCTGGACCAT GACGCAGAGC TGGCTCCCGC GTATGCCTTG 
TTGAAGAGGA TTATCCAGGC CGGATGCAGT GCAGCCATAT ATTTATCAGA AAGGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death.
Molecular pharmacology92(6)640-652(2017 Dec)
Yan Q,Han C,Wang G,Waddington JL,Zheng L,Zhen X

Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis.
Nature communications66393(2015 Mar)
Wang Y,Oxer D,Hekimi S

Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolism.
Physiological reports2(11)(2014 11)
Lapointe J,Hughes BG,Bigras E,Hekimi S

Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America111(44)E4697-705(2014 Nov)
Lohman DC,Forouhar F,Beebe ET,Stefely MS,Minogue CE,Ulbrich A,Stefely JA,Sukumar S,Luna-S?nchez M,Jochem A,Lew S,Seetharaman J,Xiao R,Wang H,Westphall MS,Wrobel RL,Everett JK,Mitchell JC,L?pez LC,Coon JJ,Tong L,Pagliarini DJ

Mitochondrial respiration without ubiquinone biosynthesis.
Human molecular genetics22(23)4768-83(2013 Dec)
Wang Y,Hekimi S

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Coq7 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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