Cdkn1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdkn1a
Entrez Gene ID	12575
Full Name	cyclin-dependent kinase inhibitor 1A (P21)
Synonyms	CAP20,CDKI,CIP1,Cdkn1,P21,SDI1,Waf1,mda6,p21Cip1,p21WAF
General protein information	Preferred Names cyclin-dependent kinase inhibitor 1A (P21) Names cyclin-dependent kinase inhibitor 1 CDK-interacting protein 1 melanoma differentiation-associated protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 A3.3\|17 15.12 cM
Summary	This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at the G1 pahse. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_007669.5	NP_031695.1	cyclin-dependent kinase inhibitor 1
NM_007669.4	NP_031695.1	cyclin-dependent kinase inhibitor 1
NM_001111099.1	NP_001104569.1	cyclin-dependent kinase inhibitor 1
NM_001111099.2	NP_001104569.1	cyclin-dependent kinase inhibitor 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cdkn1a	NP_542960.1
Pan troglodytes (chimpanzee)	CDKN1A	XP_003950884.1
Mus musculus (house mouse)	Cdkn1a	NP_031695.1
Homo sapiens (human)	CDKN1A	NP_001207706.1
Bos taurus (cattle)	CDKN1A	NP_001092428.1
	CDKN1A	XP_001116887.1
Canis lupus familiaris (dog)	CDKN1A	XP_005627336.1

Gene Ontology
Bibliography

Related articles in PubMed

Lack of p21 expression links cell cycle control and appendage regeneration in mice.
Bedelbaeva K, Snyder A, Gourevitch D, Clark L, Zhang XM, Leferovich J, Cheverud JM, Lieberman P, Heber-Katz E
Proceedings of the National Academy of Sciences of the United States of America107(13)5845-50(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study shows that p21 is upregulated in T effector cells but not natural regulatory T cells after treatment with azacitidine, which protects from graft-versus-host Disease
Title: Azacitidine Mitigates Graft-versus-Host Disease via Differential Effects on the Proliferation of T Effectors and Natural Regulatory T Cells In Vivo.

In this study, we found upregulation of several hemostasis-related genes, including the thrombin-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1/Cbfb-deleted MLL-AF9 cells. Similar to the effect of Runx1/Cbfb deletion, PAR-1 overexpression induced CDKN1A/p21 expression and attenuated proliferation in MLL-AF9 cells
Title: Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia.

The study demonstrates an essential role of Setd2 in myoblast proliferation and differentiation, and uncovers Setd2-mediated molecular mechanism through regulating MyoG and p21.
Title: Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts.

Results show that p21 expression is regulated by OLA1 to promote cell proliferation and organogenesis.
Title: OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression.

our genetic and biochemical data show an important function of p21 in the regulation of growth-related processes in the heart.
Title: p21(CIP1/WAF1)-dependent inhibition of cardiac hypertrophy in response to Angiotensin II involves Akt/Myc and pRb signaling.

The following Cdkn1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdkn1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22894	NM_001111099.2 Latest version!	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu22894	NM_007669.5 Latest version!	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu22894	NM_007669.4	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu22894	NM_001111099.1	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdkn1a ( NM_007669.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031695.1 Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu22894
Clone ID Related Accession (Same CDS sequence)	NM_007669.5 , NM_007669.4 , NM_001111099.1 , NM_001111099.2
Accession Version	NM_007669.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	cyclin-dependent kinase inhibitor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC167363.3, AK149910.1 and AK007630.1. On Sep 25, 2015 this sequence version replaced NM_007669.4. Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK007630.1, AK170467.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031695.1
CDS	105..584
Translation	MSNPGDVRPVPHRSKVCRCLFGPVDSEQLRRDCDALMAGCLQEARERWNFDFVTETPLEGNFVWERVRSLGLPKVYLSPGSRSRDDLGGDKRPSTSSALLQGPAPEDHVALSLSCTLVSERPEDSPGGPGTSQGRKRRQTSLTDFYHSKRRLVFCKRKP

Target ORF information:

RefSeq Version	NM_007669.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007669.5

ORF Insert Sequence:

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdkn1a ( NM_007669.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031695.1 Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu22894
Clone ID Related Accession (Same CDS sequence)	NM_007669.5 , NM_007669.4 , NM_001111099.1 , NM_001111099.2
Accession Version	NM_007669.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	cyclin-dependent kinase inhibitor 1
Comment

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031695.1
Translation	MSNPGDVRPVPHRSKVCRCLFGPVDSEQLRRDCDALMAGCLQEARERWNFDFVTETPLEGNFVWERVRSLGLPKVYLSPGSRSRDDLGGDKRPSTSSALLQGPAPEDHVALSLSCTLVSERPEDSPGGPGTSQGRKRRQTSLTDFYHSKRRLVFCKRKP

Target ORF information:

RefSeq Version	NM_007669.4
Organism	Mus musculus(House mouse)
Definition	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007669.4

ORF Insert Sequence:

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdkn1a ( NM_001111099.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104569.1 Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu22894
Clone ID Related Accession (Same CDS sequence)	NM_007669.5 , NM_007669.4 , NM_001111099.1 , NM_001111099.2
Accession Version	NM_001111099.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	cyclin-dependent kinase inhibitor 1
Comment

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104569.1
Translation	MSNPGDVRPVPHRSKVCRCLFGPVDSEQLRRDCDALMAGCLQEARERWNFDFVTETPLEGNFVWERVRSLGLPKVYLSPGSRSRDDLGGDKRPSTSSALLQGPAPEDHVALSLSCTLVSERPEDSPGGPGTSQGRKRRQTSLTDFYHSKRRLVFCKRKP

Target ORF information:

RefSeq Version	NM_001111099.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001111099.1

ORF Insert Sequence:

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdkn1a ( NM_001111099.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104569.1 Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu22894
Clone ID Related Accession (Same CDS sequence)	NM_007669.5 , NM_007669.4 , NM_001111099.1 , NM_001111099.2
Accession Version	NM_001111099.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	cyclin-dependent kinase inhibitor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC167363.3, BY206886.1, AK149910.1 and AK007630.1. On Sep 25, 2015 this sequence version replaced NM_001111099.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK007630.1, SRR1660811.114989.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104569.1
CDS	135..614
Translation	MSNPGDVRPVPHRSKVCRCLFGPVDSEQLRRDCDALMAGCLQEARERWNFDFVTETPLEGNFVWERVRSLGLPKVYLSPGSRSRDDLGGDKRPSTSSALLQGPAPEDHVALSLSCTLVSERPEDSPGGPGTSQGRKRRQTSLTDFYHSKRRLVFCKRKP

Target ORF information:

RefSeq Version	NM_001111099.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001111099.2

ORF Insert Sequence:

ATGTCCAATC CTGGTGATGT CCGACCTGTT CCGCACAGGA GCAAAGTGTG CCGTTGTCTC 
TTCGGTCCCG TGGACAGTGA GCAGTTGCGC CGTGATTGCG ATGCGCTCAT GGCGGGCTGT 
CTCCAGGAGG CCCGAGAACG GTGGAACTTT GACTTCGTCA CGGAGACGCC GCTGGAGGGC 
AACTTCGTCT GGGAGCGCGT TCGGAGCCTA GGGCTGCCCA AGGTCTACCT GAGCCCTGGG 
TCCCGCAGCC GTGACGACCT GGGAGGGGAC AAGAGGCCCA GTACTTCCTC TGCCCTGCTG 
CAGGGGCCAG CTCCGGAGGA CCACGTGGCC TTGTCGCTGT CTTGCACTCT GGTGTCTGAG 
CGGCCTGAAG ATTCCCCGGG TGGGCCCGGA ACATCTCAGG GCCGAAAACG GAGGCAGACC 
AGCCTGACAG ATTTCTATCA CTCCAAGCGC AGATTGGTCT TCTGCAAGAG AAAACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lack of p21 expression links cell cycle control and appendage regeneration in mice.
Proceedings of the National Academy of Sciences of the United States of America107(13)5845-50(2010 Mar)
Bedelbaeva K,Snyder A,Gourevitch D,Clark L,Zhang XM,Leferovich J,Cheverud JM,Lieberman P,Heber-Katz E

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Cdkn1a cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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