Cdk5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdk5
Entrez Gene ID	12568
Full Name	cyclin-dependent kinase 5
Synonyms	AW048668,Crk6
General protein information	Preferred Names cyclin-dependent kinase 5 Names cyclin-dependent-like kinase 5 CR6 protein kinase TPKII catalytic subunit cell division protein kinase 5 serine/threonine-protein kinase PSSALRE tau protein kinase II catalytic subunit
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 A3\|5 11.73 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006535626.3	XP_006535689.1	cyclin-dependent-like kinase 5 isoform X1
NM_007668.4	NP_031694.1	cyclin-dependent-like kinase 5
NM_007668.3	NP_031694.1	cyclin-dependent-like kinase 5
XM_006535626.2	XP_006535689.1	cyclin-dependent-like kinase 5 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cdk5	NP_543161.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005772	XP_315787.4
Saccharomyces cerevisiae (baker's yeast)	PHO85	NP_015294.1
Neurospora crassa	NCU07580	XP_958274.1
Xenopus tropicalis (tropical clawed frog)	cdk5	NP_001072776.1
Homo sapiens (human)	CDK5	NP_004926.1
	CDK5	XP_001102523.1
Canis lupus familiaris (dog)	CDK5	XP_005629809.1
Bos taurus (cattle)	CDK5	NP_776442.1
Gallus gallus (chicken)	CDK5	NP_001129258.1
Eremothecium gossypii	AGOS_AGL242C	NP_986425.2
Pan troglodytes (chimpanzee)	CDK5	XP_519523.2
Mus musculus (house mouse)	Cdk5	NP_031694.1
Danio rerio (zebrafish)	cdk5	NP_571794.1
Drosophila melanogaster (fruit fly)	Cdk5	NP_477080.1
Caenorhabditis elegans (roundworm)	cdk-5	NP_499783.1
Kluyveromyces lactis	KLLA0D11990g	XP_453596.1
Schizosaccharomyces pombe (fission yeast)	pef1	NP_587921.1
Magnaporthe oryzae (rice blast fungus)	MGG_04660	XP_003713655.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of Cdk5-mediated Drp1 phosphorylation in A?
Guo MY, Shang L, Hu YY, Jiang LP, Wan YY, Zhou QQ, Zhang K, Liao HF, Yi JL, Han XJ
Journal of cellular biochemistry(2018 Jan)

Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception.
Hall BE, Prochazkova M, Sapio MR, Minetos P, Kurochkina N, Binukumar BK, Amin ND, Terse A, Joseph J, Raithel SJ, Mannes AJ, Pant HC, Chung MK, Iadarola MJ, Kulkarni AB
Scientific reports8(1)1177(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cdk5 may play an important role in endoplasmic reticulum stress induced podocyte apoptosis through MEKK1/JNK pathway in diabetic nephropathy.
Title: Cyclin-dependent kinase 5 contributes to endoplasmic reticulum stress induced podocyte apoptosis via promoting MEKK1 phosphorylation at Ser280 in diabetic nephropathy.

Cdk5 regulates axon outgrowth through the GRAB-mediated Rab8-Rab11 cascade.
Title: Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth.

we report a key role for Cdk5 activity in the development of allogeneic T-cell responses after allogeneic hematopoietic cell transplantation
Title: Cyclin-dependent kinase 5 activity is required for allogeneic T-cell responses after hematopoietic cell transplantation in mice.

In this study, we discovered that selective upregulation of p39 is the underlying mechanism that accommodates the increased functional requirement of Cdk5 activation during neuronal differentiation. In addition, we demonstrated that p39 selectively directs Cdk5 to phosphorylate protein substrates essential for axonal development, dendritic spine formation, and synaptogenesis. Moreover, our studies suggest opposing roles o
Title: p39 Is Responsible for Increasing Cdk5 Activity during Postnatal Neuron Differentiation and Governs Neuronal Network Formation and Epileptic Responses.

these results show that Cdk5-mediated phospho-regulation of Foxo3 can activate several genes that promote neuronal death and aberrant Abeta processing, thereby contributing to the progression of neurodegenerative pathologies.
Title: Cdk5-Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models.

The following Cdk5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdk5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19186	NM_007668.4 Latest version!	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu34714	XM_006535626.3 Latest version!	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu19186	NM_007668.3	Mus musculus cyclin-dependent kinase 5 (Cdk5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu34714	XM_006535626.2	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdk5 ( NM_007668.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031694.1 Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19186
Clone ID Related Accession (Same CDS sequence)	NM_007668.4 , NM_007668.3
Accession Version	NM_007668.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	cyclin-dependent-like kinase 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY126868.1, AK051790.1 and AI550418.1. On May 9, 2018 this sequence version replaced NM_007668.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660821.71383.1, SRR1660815.227229.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGAACCTATT GAAGTGTAAC CCTGTGCAGC GCATCTCAGC AGAGGAGGCC 
TTGCAGCACC CCTACTTCTC TGACTTCTGT CCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031694.1
CDS	80..958
Translation	MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

Target ORF information:

RefSeq Version	NM_007668.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007668.4

ORF Insert Sequence:

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGAACCTATT GAAGTGTAAC CCTGTGCAGC GCATCTCAGC AGAGGAGGCC 
TTGCAGCACC CCTACTTCTC TGACTTCTGT CCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdk5 ( NM_007668.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031694.1 Mus musculus cyclin-dependent kinase 5 (Cdk5), mRNA.

Price & Availability↑

CloneID	OMu19186
Clone ID Related Accession (Same CDS sequence)	NM_007668.4 , NM_007668.3
Accession Version	NM_007668.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-09
Organism	Mus musculus(house mouse)
Product	cyclin-dependent-like kinase 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK051790.1. On Apr 6, 2007 this sequence version replaced NM_007668.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK051790.1, SRR1660821.71383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGAACCTATT GAAGTGTAAC CCTGTGCAGC GCATCTCAGC AGAGGAGGCC 
TTGCAGCACC CCTACTTCTC TGACTTCTGT CCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031694.1
CDS	46..924
Translation	MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

Target ORF information:

RefSeq Version	NM_007668.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase 5 (Cdk5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007668.3

ORF Insert Sequence:

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGAACCTATT GAAGTGTAAC CCTGTGCAGC GCATCTCAGC AGAGGAGGCC 
TTGCAGCACC CCTACTTCTC TGACTTCTGT CCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdk5 ( XM_006535626.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006535689.1 Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34714
Clone ID Related Accession (Same CDS sequence)	XM_006535626.3 , XM_006535626.2
Accession Version	XM_006535626.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	cyclin-dependent-like kinase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006535626.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGGTGCATCT CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006535689.1
CDS	99..908
Translation	MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQVHLLR

Target ORF information:

RefSeq Version	XM_006535626.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006535626.2

ORF Insert Sequence:

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGGTGCATCT CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdk5 ( XM_006535626.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006535689.1 Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34714
Clone ID Related Accession (Same CDS sequence)	XM_006535626.3 , XM_006535626.2
Accession Version	XM_006535626.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	cyclin-dependent-like kinase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006535626.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGGTGCATCT CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006535689.1
CDS	103..912
Translation	MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQVHLLR

Target ORF information:

RefSeq Version	XM_006535626.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin-dependent kinase 5 (Cdk5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006535626.3

ORF Insert Sequence:

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTATGGAAC TGTGTTCAAG 
GCTAAAAACC GGGAAACTCA TGAGATTGTG GCTCTGAAGC GTGTCAGGCT GGATGATGAC 
GATGAGGGTG TGCCAAGTTC AGCCCTCCGG GAGATCTGTC TACTCAAAGA ACTGAAGCAC 
AAAAACATTG TCAGGCTTCA TGATGTCCTG CATAGTGACA AGAAGCTGAC ACTGGTTTTT 
GAGTTCTGTG ATCAGGACCT GAAGAAATAT TTCGACAGCT GCAATGGTGA CCTGGACCCT 
GAGATTGTGA AGTCATTCCT CTTCCAGCTG CTGAAAGGCC TGGGATTCTG TCACAGCCGC 
AACGTGCTAC ATAGGGACCT GAAGCCCCAG AACCTGCTCA TAAACAGGAA TGGGGAGTTG 
AAATTGGCTG ATTTTGGCCT GGCCCGAGCC TTTGGTATCC CCGTCCGCTG CTACTCTGCT 
GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCTAA TGCAGGACGA 
CCTCTCTTCC CTGGCAATGA TGTGGATGAC CAGCTGAAGA GGATCTTCCG ACTGCTAGGG 
ACACCGACTG AGGAACAATG GCCTGCCATG ACCAAGCTGC CAGACTATAA GCCCTACCCA 
ATGTACCCAG CTACAACATC CTTGGTGAAC GTCGTGCCCA AGCTCAATGC CACGGGGAGG 
GACCTGTTGC AGGTGCATCT CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of Cdk5-mediated Drp1 phosphorylation in A?
Journal of cellular biochemistry(2018 Jan)
Guo MY,Shang L,Hu YY,Jiang LP,Wan YY,Zhou QQ,Zhang K,Liao HF,Yi JL,Han XJ

Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception.
Scientific reports8(1)1177(2018 Jan)
Hall BE,Prochazkova M,Sapio MR,Minetos P,Kurochkina N,Binukumar BK,Amin ND,Terse A,Joseph J,Raithel SJ,Mannes AJ,Pant HC,Chung MK,Iadarola MJ,Kulkarni AB

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Cdk5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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