Arhgap31 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arhgap31
Entrez Gene ID	12549
Full Name	Rho GTPase activating protein 31
Synonyms	5830477L08Rik,AU041750,Cdgap,D330026I07Rik
General protein information	Preferred Names Rho GTPase activating protein 31 Names rho GTPase-activating protein 31 CDC42 GTPase-activating protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B4

mRNA and Protein(s)

mRNA	Protein	Name
NM_020260.2	NP_064656.2	rho GTPase-activating protein 31

Pathways from BioSystems

Homologies

Homo sapiens (human)	ARHGAP31	NP_065805.2
	ARHGAP31	XP_002802733.1
Bos taurus (cattle)	ARHGAP31	NP_001192739.1
Pan troglodytes (chimpanzee)	ARHGAP31	XP_001162142.1
Canis lupus familiaris (dog)	ARHGAP31	XP_005639581.1
Rattus norvegicus (Norway rat)	Arhgap31	NP_001099349.1
Mus musculus (house mouse)	Arhgap31	NP_064656.2

Gene Ontology
Bibliography

Related articles in PubMed

CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.
Caron C, DeGeer J, Fournier P, Duquette PM, Luangrath V, Ishii H, Karimzadeh F, Lamarche-Vane N, Royal I
Scientific reports627485(2016 Jun)

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Maga AM, Navarro N, Cunningham ML, Cox TC
Frontiers in physiology692(2015)

ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.
Naji L, Pacholsky D, Aspenstr?m P
Biochemical and biophysical research communications409(1)96-102(2011 May)

Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies.
Southgate L, Machado RD, Snape KM, Primeau M, Dafou D, Ruddy DM, Branney PA, Fisher M, Lee GJ, Simpson MA, He Y, Bradshaw TY, Blaumeiser B, Winship WS, Reardon W, Maher ER, FitzPatrick DR, Wuyts W, Zenker M, Lamarche-Vane N, Trembath RC
American journal of human genetics88(5)574-85(2011 May)

Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif.
Primeau M, Ben Djoudi Ouadda A, Lamarche-Vane N
FEBS letters585(6)847-53(2011 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increased levels of endogenous CdGAP in mammary tumor explant cells resulted in increased cell motility and invasion in response to TGF-beta, and downregulation by siRNA inhibited cell motility and invasion. CdGAP is required for TGF-beta effects.
Title: CdGAP is required for transforming growth factor ?- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

Data show that intersectin-SH3D interacts directly with a small region of CdGAP highly enriched in basic residues and comprising a novel conserved xKx(K/R)K motif.
Title: Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif.

Nudel facilitates cell migration by sequestering Cdc42GAP at the leading edge to stabilize active Cdc42 in response to extracellular stimuli.
Title: Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.

CdGAP is a novel substrate of extracellular signal-regulated kinase (ERK)1/2 and mediates cross talk between the Ras/mitogen-activated protein kinase pathway and regulation of Rac1 activity.
Title: Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site.

The following Arhgap31 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgap31 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11967	NM_020260.2 Latest version!	Mus musculus Rho GTPase activating protein 31 (Arhgap31), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$839.30 $1199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arhgap31 ( NM_020260.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064656.2 Mus musculus Rho GTPase activating protein 31 (Arhgap31), mRNA.

Price & Availability↑

CloneID	OMu11967
Clone ID Related Accession (Same CDS sequence)	NM_020260.2
Accession Version	NM_020260.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	rho GTPase-activating protein 31
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB865916.1, AF151363.1 and AK129309.1. On Nov 15, 2004 this sequence version replaced NM_020260.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC138870.1, AK155729.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAACA AGGGTGCCAA GCAGAAGCTG AAACGAAAGG GAGCCGCCAG TGCGTTTGGA 
TGTGACCTGA CGGAGTATCT GGAAAGTTCG GGACAGGATG TTCCATATGT GCTGAAGAGC 
TGTGCTGAAT TCATAGAGAC TCACGGCATT GTGGATGGAA TCTATCGCCT CTCGGGCATC 
ACCTCAAACA TCCAGCGGCT GAGGCAAGAG TTTGGCTCAG ATCAATGCCC AGATCTGACA 
AGGGAAGTGT ACCTTCAAGA CATCCACTGT GTGGGCTCCT TGTGCAAGCT CTACTTCCGG 
GAGCTGCCCA ACCCCCTCCT GACCTACGAG CTCTATGAGA AATTCACGGA AGCAGTGTCT 
CATCGCCCAG AAGAAGGCCA GCTGGCCAGA ATCCAGAATG TTATCCTGGA GCTTCCCCCA 
CCCCATTATA GGACCTTGGA ATACCTGATT CGACACCTGG CCCACATCGC CTCATTCAGC 
AGCAAGACCA ACATGCACGC CAGGAACCTG GCCCTGGTGT GGGCCCCAAA CCTCCTCAGG 
AGTAAGAAAA TCGAAGCCAC TATTTGCAAT GGAGATGCGG CGTTTCTGGC AGTCCGGGTC 
CAGCAGGTGG TGATTGAGTT CATATTAAAT CACGCTGATC AAATCTTCAA TGGCGGTGCT 
CCAGGGGCTC TGCAGCAGGA TGAAAGCCGT ACTATCACAA AGAGCCTGAC CTTGCCAGCC 
TTGTCCCTGC CCATGAAGTT GGTAAGCCTG GAGGAGGCTC AGGCCCGAAG CTTGGCGACA 
AACCACCCTG CTCGGAAGGA AAGACGAGAG AACAGCCTGC CCGAGATCGT CCCTCCTCCC 
TTCCACACCG TCCTTGAGTT ACCAGACAAC AAGAGAAAGC TTTCCAGCAA ATCAAAGAAG 
TGGAAATCGA TATTTAACCT GGGACGTTCT GGATCGGACT CGAAGTCCAA GCTGAGTAGA 
AACGGGAGTG TGTTCGTGAG AGGCCAGAGG CTGTCAGTGG AAAAGGCTAC TATCCGGCCA 
GCAAAAAGCA TGGACTCACT GTGTTCGGTG CCTGTGGAAG GGAAAGAAAA CAAAGGAAAT 
TTCAGTCGAA CAGTCACCAC TGGGGGATTT TTCATTCCAG CCACAAAAAT GCACGCGAGC 
AGCACCGGAA GCTCCTGTGA CCTCAGCAAG GAGGGTGAAT GGGGTCAGGA GGGGATGCCC 
GCAGGGGCTG AGGGGGGCTG CGAGGTGGGC GGTCAGATCC GGCCACTGCC TGAGCAGCTG 
AAGGTGTTCC GCCCCATCGG AGACCCTGAG AGCGAGCAGT CCGCCCCAAA GCTTCTCGGG 
ATGTTCTACA CCTCCAGCGA CAGTCCTGGC AAATCTGTCT TCACAAGCAG CCTGTTCCAG 
ATGGAACCCT CACCCCGCCA CCAGCGAAAG GCGCTCAACA TCTCCGAGCC CTTCGCCGTG 
TCTGTGCCAC TCCGCGTGTC CGCCGTCATC AGTACCAACA GCACCCCGTG CAGGACACCC 
CCCAAAGAGC TACAGTCTCT CTCCAGCCTC GAAGAGTTTT CTTTCCAAGG TTCAGAGAGT 
GGAGGATGGC CAGAAGAAGA GAAGCCCCTG GGGGCTGAGT CTTTTCCAGG CTCTGTTACT 
AAGAAGGCAG CTACCGAGGA CACCAAGCCA GAACCTGAAG TCCCGGGGAG AGCAGAATGT 
AGCCAAAGCC CTCCCCTGGA CCCAGGCACC CAAGTGGAGA AGAAAACCTT GCATGTATCC 
CTGGGCTCTC AAGTATCAAA GGAAGCAGAG AAGCGGCCAA AGGCTGAGAA GGTGATGGAG 
GAGAGCCAGG GTGCTAGCCA GCCGAAGCCC AGCACTCCAC AAGAGAGCCT CGGGGCTGGG 
ACTGAACCAT TGATTCTCCA CGAGATGGAT GAAGAAGACC TGGCTCAGGC CTTGATCTGG 
CCTGAGATTC AACAGGAACT GAAAATCATT GAATCAGAGG AGGAGTTCTC TTCCTTGCCA 
CCCGCTGCTC AGAAGACAAG CCCGATTCCT GAGTCAAGCC CAGCCCCATT TCCCTTCCCA 
GAAGCCCCTG GGAGCTTGCC TAGTAGCTCT GCTCCTCGGG AGGTGTGGAC TAGGGACGCA 
GCCAATCAGA GCATACAGGA AGCTGCTATC CTCACTGACA GAGAGAAGCT AGAGCCAGTC 
TGCAGCCTCC TCGAGTCAGA GTCTCAGCAG GAGCTCAGCC CAGACCCAGC CAGTCTAGCG 
CCTCTGGAAA TGCTTCTGTT TGAGAAGGTA TCTTCTCCGG CTAGGATAGA GATAGGAGGC 
CCAAGGAATC TCTCTCCCCC TCTTACTCCT GCTCCTCCTC CCCCCACACC TCTGGAGGAG 
GAGCCTGAAG TCCTGCTGTC AAAGGAAGGT CCTGACAGGG AAGATGCAGC CAGGGATTCC 
AGGACAGATG TCTACACAGA GCAGCCAACC CCCAAAGAGA GCCCTGGCAT CCCTACCCCC 
TGTCAGAGAG AGGAAGCTAT TGCAAGCCCA AATGAGAAGC AAAACGCAAG GCATGCTGTT 
CCTGAGAACA AAGGCCCTGG TCTTCCAAGC CCAACCAAAG AGGTTGACAT CATCCCACAA 
GAGGAGGGAG GTGCTCCGCA TTCAGCACAA GAGCCTTCAG ACTGTGACGA AGATGACACT 
GTGACGGACC CTGCCCAGCA TGGCCTGGAG ATGGTGGAAC CCTGGGAGGA ACCCCAGTGG 
GTGACCAGTC CCCTTCATTC TCCCACCTTG AAAGAAGTTC AGGAGTCCCA GACGCAAGGC 
TCCCAGGGCC ACCGATTAGA GAGGAGACTT TGCCACAGGC CCAGCCTTCG CCAGAGCCAT 
TCTCTCGATA GTAAAACCAC TGGAAACAGC CACTGGACTC TTGAGGCGCC CTTCTCCAGC 
AGTTGTGCCA ATCTGGAAAC AGAGAGGAAC TATGAGCCTC TGCAGCCCCC GGCAGCCAGG 
ACCAAGATTG CCGGATTGGA AGAGAAAGCC CTAAAAGCCT TCAGAGAGTT CTCTGGCCTG 
AAAGGGTTAG AGGTTCTTCC CAGTCAGAAG GGACCATCTG GTATACAACC CAAACCAGTA 
GAAACCAACT TCATGGGTTT AGCAGAGGGA AAGGAGCAGG AACCACAACT GGAACTTAGC 
AACCGTCAGA TGAAACACAG TGATGTTCCC GGGCCAGATA GCAGCAAGGA GAGTTCACCG 
AGGGCTCAAG ACAGCACCTT ACCTGGGGAA CATCCCTTAC AGTTACAGCT TAAGAACACT 
GAGTGTGGGC CCTCAAAAGG GAAACACAGG CCGTCTTCCC TCAACCTGGA CTCTGCCACT 
CCCATAGCTG ACCTTTTCCG ACTTGAGAAT GGGGCTCCCT TTAGCTCACC TGGAATAGAG 
CTCTCTGAAC TAGGAGACAC CAAGGTCACC TGGATGAGCT CCTCTCACTG CAAAGCAGCC 
CCCTGGAATT CCCAGGACAC GCAGGACCTG GACATTGTTG CCCACACCCT GACAGGCCGC 
AGGAATTCGG CTCCTGTAAG TGTGTCAGCT GTGAGAACCT CCTTCATGGT CAAAATGTGT 
CAGGCCAAGG CAGTCCCTGT CATCCCACCC AAGATCCAAT ACACACAGAT CCCACAGCCC 
CTGCCCTCTC AGAGCACAGG GGAGGGAGGG GCTCAGCCTC TGGAGAGAAG CCAGGAAGAA 
CCTGGTTCAA CCCCTGAGAT CCCTCAGAAA TCCACCAAAG ATGATTCTCC CTCCTCCCTG 
GGAAGCCCAG AGGAAGAGCA ACCAAAGCAA GAGACAGGAG CCTCCGCATC CCGGAGGCAG 
GCCAGCATTA CATCCTGCAT GTATGAGGGG TCCTCCTGCT CTCCAGAACC AAGTGCATCC 
ACTCTGGCCT CCACACAGGA TGCGGTGGTG CAATGCAGAA AACGCACATC AGAGACAGAG 
CCATCAGGAG ACAACCTTCT TTCTTCCAAA CTGGAGCGAG CATCTGGGGG TCCTAAAGCT 
TTCCACAGGT CAAGGCCAGG AAGACCTCAG AGCCTAATCT TATTCCCTAT CATGGACCAT 
CTACCTTCCT CACCCACAGT GATAGATTCC AAGGTCCTAC TGTCCCCTAT CAGGAGCCCT 
ACTCAGACAG TTTCCCCTGG TCTTCTCTGT GGAGAGTTGG CCGAAAACAC ATGGATCACA 
CCAGAAGGGG TCACGCTTAG GAATAAAATG ACCATCCCTA AGAATGGCCA AAGACTCGAG 
ACTTCGACAA GCTGTTTTTA CCAGCCCCAG CGGAGATCCG TGATTCTGGA TGGAAGAAGT 
GGGAGACAGA TAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064656.2
CDS	363..4640
Translation	MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGITSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVILELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTITKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFSRTVTTGGFFIPATKMHASSTGSSCDLSKEGEWGQEGMPAGAEGGCEVGGQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKSVFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFQGSESGGWPEEEKPLGAESFPGSVTKKAATEDTKPEPEVPGRAECSQSPPLDPGTQVEKKTLHVSLGSQVSKEAEKRPKAEKVMEESQGASQPKPSTPQESLGAGTEPLILHEMDEEDLAQALIWPEIQQELKIIESEEEFSSLPPAAQKTSPIPESSPAPFPFPEAPGSLPSSSAPREVWTRDAANQSIQEAAILTDREKLEPVCSLLESESQQELSPDPASLAPLEMLLFEKVSSPARIEIGGPRNLSPPLTPAPPPPTPLEEEPEVLLSKEGPDREDAARDSRTDVYTEQPTPKESPGIPTPCQREEAIASPNEKQNARHAVPENKGPGLPSPTKEVDIIPQEEGGAPHSAQEPSDCDEDDTVTDPAQHGLEMVEPWEEPQWVTSPLHSPTLKEVQESQTQGSQGHRLERRLCHRPSLRQSHSLDSKTTGNSHWTLEAPFSSSCANLETERNYEPLQPPAARTKIAGLEEKALKAFREFSGLKGLEVLPSQKGPSGIQPKPVETNFMGLAEGKEQEPQLELSNRQMKHSDVPGPDSSKESSPRAQDSTLPGEHPLQLQLKNTECGPSKGKHRPSSLNLDSATPIADLFRLENGAPFSSPGIELSELGDTKVTWMSSSHCKAAPWNSQDTQDLDIVAHTLTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQSTGEGGAQPLERSQEEPGSTPEIPQKSTKDDSPSSLGSPEEEQPKQETGASASRRQASITSCMYEGSSCSPEPSASTLASTQDAVVQCRKRTSETEPSGDNLLSSKLERASGGPKAFHRSRPGRPQSLILFPIMDHLPSSPTVIDSKVLLSPIRSPTQTVSPGLLCGELAENTWITPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE

Target ORF information:

RefSeq Version	NM_020260.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus Rho GTPase activating protein 31 (Arhgap31), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020260.2

ORF Insert Sequence:

ATGAAGAACA AGGGTGCCAA GCAGAAGCTG AAACGAAAGG GAGCCGCCAG TGCGTTTGGA 
TGTGACCTGA CGGAGTATCT GGAAAGTTCG GGACAGGATG TTCCATATGT GCTGAAGAGC 
TGTGCTGAAT TCATAGAGAC TCACGGCATT GTGGATGGAA TCTATCGCCT CTCGGGCATC 
ACCTCAAACA TCCAGCGGCT GAGGCAAGAG TTTGGCTCAG ATCAATGCCC AGATCTGACA 
AGGGAAGTGT ACCTTCAAGA CATCCACTGT GTGGGCTCCT TGTGCAAGCT CTACTTCCGG 
GAGCTGCCCA ACCCCCTCCT GACCTACGAG CTCTATGAGA AATTCACGGA AGCAGTGTCT 
CATCGCCCAG AAGAAGGCCA GCTGGCCAGA ATCCAGAATG TTATCCTGGA GCTTCCCCCA 
CCCCATTATA GGACCTTGGA ATACCTGATT CGACACCTGG CCCACATCGC CTCATTCAGC 
AGCAAGACCA ACATGCACGC CAGGAACCTG GCCCTGGTGT GGGCCCCAAA CCTCCTCAGG 
AGTAAGAAAA TCGAAGCCAC TATTTGCAAT GGAGATGCGG CGTTTCTGGC AGTCCGGGTC 
CAGCAGGTGG TGATTGAGTT CATATTAAAT CACGCTGATC AAATCTTCAA TGGCGGTGCT 
CCAGGGGCTC TGCAGCAGGA TGAAAGCCGT ACTATCACAA AGAGCCTGAC CTTGCCAGCC 
TTGTCCCTGC CCATGAAGTT GGTAAGCCTG GAGGAGGCTC AGGCCCGAAG CTTGGCGACA 
AACCACCCTG CTCGGAAGGA AAGACGAGAG AACAGCCTGC CCGAGATCGT CCCTCCTCCC 
TTCCACACCG TCCTTGAGTT ACCAGACAAC AAGAGAAAGC TTTCCAGCAA ATCAAAGAAG 
TGGAAATCGA TATTTAACCT GGGACGTTCT GGATCGGACT CGAAGTCCAA GCTGAGTAGA 
AACGGGAGTG TGTTCGTGAG AGGCCAGAGG CTGTCAGTGG AAAAGGCTAC TATCCGGCCA 
GCAAAAAGCA TGGACTCACT GTGTTCGGTG CCTGTGGAAG GGAAAGAAAA CAAAGGAAAT 
TTCAGTCGAA CAGTCACCAC TGGGGGATTT TTCATTCCAG CCACAAAAAT GCACGCGAGC 
AGCACCGGAA GCTCCTGTGA CCTCAGCAAG GAGGGTGAAT GGGGTCAGGA GGGGATGCCC 
GCAGGGGCTG AGGGGGGCTG CGAGGTGGGC GGTCAGATCC GGCCACTGCC TGAGCAGCTG 
AAGGTGTTCC GCCCCATCGG AGACCCTGAG AGCGAGCAGT CCGCCCCAAA GCTTCTCGGG 
ATGTTCTACA CCTCCAGCGA CAGTCCTGGC AAATCTGTCT TCACAAGCAG CCTGTTCCAG 
ATGGAACCCT CACCCCGCCA CCAGCGAAAG GCGCTCAACA TCTCCGAGCC CTTCGCCGTG 
TCTGTGCCAC TCCGCGTGTC CGCCGTCATC AGTACCAACA GCACCCCGTG CAGGACACCC 
CCCAAAGAGC TACAGTCTCT CTCCAGCCTC GAAGAGTTTT CTTTCCAAGG TTCAGAGAGT 
GGAGGATGGC CAGAAGAAGA GAAGCCCCTG GGGGCTGAGT CTTTTCCAGG CTCTGTTACT 
AAGAAGGCAG CTACCGAGGA CACCAAGCCA GAACCTGAAG TCCCGGGGAG AGCAGAATGT 
AGCCAAAGCC CTCCCCTGGA CCCAGGCACC CAAGTGGAGA AGAAAACCTT GCATGTATCC 
CTGGGCTCTC AAGTATCAAA GGAAGCAGAG AAGCGGCCAA AGGCTGAGAA GGTGATGGAG 
GAGAGCCAGG GTGCTAGCCA GCCGAAGCCC AGCACTCCAC AAGAGAGCCT CGGGGCTGGG 
ACTGAACCAT TGATTCTCCA CGAGATGGAT GAAGAAGACC TGGCTCAGGC CTTGATCTGG 
CCTGAGATTC AACAGGAACT GAAAATCATT GAATCAGAGG AGGAGTTCTC TTCCTTGCCA 
CCCGCTGCTC AGAAGACAAG CCCGATTCCT GAGTCAAGCC CAGCCCCATT TCCCTTCCCA 
GAAGCCCCTG GGAGCTTGCC TAGTAGCTCT GCTCCTCGGG AGGTGTGGAC TAGGGACGCA 
GCCAATCAGA GCATACAGGA AGCTGCTATC CTCACTGACA GAGAGAAGCT AGAGCCAGTC 
TGCAGCCTCC TCGAGTCAGA GTCTCAGCAG GAGCTCAGCC CAGACCCAGC CAGTCTAGCG 
CCTCTGGAAA TGCTTCTGTT TGAGAAGGTA TCTTCTCCGG CTAGGATAGA GATAGGAGGC 
CCAAGGAATC TCTCTCCCCC TCTTACTCCT GCTCCTCCTC CCCCCACACC TCTGGAGGAG 
GAGCCTGAAG TCCTGCTGTC AAAGGAAGGT CCTGACAGGG AAGATGCAGC CAGGGATTCC 
AGGACAGATG TCTACACAGA GCAGCCAACC CCCAAAGAGA GCCCTGGCAT CCCTACCCCC 
TGTCAGAGAG AGGAAGCTAT TGCAAGCCCA AATGAGAAGC AAAACGCAAG GCATGCTGTT 
CCTGAGAACA AAGGCCCTGG TCTTCCAAGC CCAACCAAAG AGGTTGACAT CATCCCACAA 
GAGGAGGGAG GTGCTCCGCA TTCAGCACAA GAGCCTTCAG ACTGTGACGA AGATGACACT 
GTGACGGACC CTGCCCAGCA TGGCCTGGAG ATGGTGGAAC CCTGGGAGGA ACCCCAGTGG 
GTGACCAGTC CCCTTCATTC TCCCACCTTG AAAGAAGTTC AGGAGTCCCA GACGCAAGGC 
TCCCAGGGCC ACCGATTAGA GAGGAGACTT TGCCACAGGC CCAGCCTTCG CCAGAGCCAT 
TCTCTCGATA GTAAAACCAC TGGAAACAGC CACTGGACTC TTGAGGCGCC CTTCTCCAGC 
AGTTGTGCCA ATCTGGAAAC AGAGAGGAAC TATGAGCCTC TGCAGCCCCC GGCAGCCAGG 
ACCAAGATTG CCGGATTGGA AGAGAAAGCC CTAAAAGCCT TCAGAGAGTT CTCTGGCCTG 
AAAGGGTTAG AGGTTCTTCC CAGTCAGAAG GGACCATCTG GTATACAACC CAAACCAGTA 
GAAACCAACT TCATGGGTTT AGCAGAGGGA AAGGAGCAGG AACCACAACT GGAACTTAGC 
AACCGTCAGA TGAAACACAG TGATGTTCCC GGGCCAGATA GCAGCAAGGA GAGTTCACCG 
AGGGCTCAAG ACAGCACCTT ACCTGGGGAA CATCCCTTAC AGTTACAGCT TAAGAACACT 
GAGTGTGGGC CCTCAAAAGG GAAACACAGG CCGTCTTCCC TCAACCTGGA CTCTGCCACT 
CCCATAGCTG ACCTTTTCCG ACTTGAGAAT GGGGCTCCCT TTAGCTCACC TGGAATAGAG 
CTCTCTGAAC TAGGAGACAC CAAGGTCACC TGGATGAGCT CCTCTCACTG CAAAGCAGCC 
CCCTGGAATT CCCAGGACAC GCAGGACCTG GACATTGTTG CCCACACCCT GACAGGCCGC 
AGGAATTCGG CTCCTGTAAG TGTGTCAGCT GTGAGAACCT CCTTCATGGT CAAAATGTGT 
CAGGCCAAGG CAGTCCCTGT CATCCCACCC AAGATCCAAT ACACACAGAT CCCACAGCCC 
CTGCCCTCTC AGAGCACAGG GGAGGGAGGG GCTCAGCCTC TGGAGAGAAG CCAGGAAGAA 
CCTGGTTCAA CCCCTGAGAT CCCTCAGAAA TCCACCAAAG ATGATTCTCC CTCCTCCCTG 
GGAAGCCCAG AGGAAGAGCA ACCAAAGCAA GAGACAGGAG CCTCCGCATC CCGGAGGCAG 
GCCAGCATTA CATCCTGCAT GTATGAGGGG TCCTCCTGCT CTCCAGAACC AAGTGCATCC 
ACTCTGGCCT CCACACAGGA TGCGGTGGTG CAATGCAGAA AACGCACATC AGAGACAGAG 
CCATCAGGAG ACAACCTTCT TTCTTCCAAA CTGGAGCGAG CATCTGGGGG TCCTAAAGCT 
TTCCACAGGT CAAGGCCAGG AAGACCTCAG AGCCTAATCT TATTCCCTAT CATGGACCAT 
CTACCTTCCT CACCCACAGT GATAGATTCC AAGGTCCTAC TGTCCCCTAT CAGGAGCCCT 
ACTCAGACAG TTTCCCCTGG TCTTCTCTGT GGAGAGTTGG CCGAAAACAC ATGGATCACA 
CCAGAAGGGG TCACGCTTAG GAATAAAATG ACCATCCCTA AGAATGGCCA AAGACTCGAG 
ACTTCGACAA GCTGTTTTTA CCAGCCCCAG CGGAGATCCG TGATTCTGGA TGGAAGAAGT 
GGGAGACAGA TAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.
Scientific reports627485(2016 Jun)
Caron C,DeGeer J,Fournier P,Duquette PM,Luangrath V,Ishii H,Karimzadeh F,Lamarche-Vane N,Royal I

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Frontiers in physiology692(2015)
Maga AM,Navarro N,Cunningham ML,Cox TC

ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.
Biochemical and biophysical research communications409(1)96-102(2011 May)
Naji L,Pacholsky D,Aspenstr?m P

Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies.
American journal of human genetics88(5)574-85(2011 May)
Southgate L,Machado RD,Snape KM,Primeau M,Dafou D,Ruddy DM,Branney PA,Fisher M,Lee GJ,Simpson MA,He Y,Bradshaw TY,Blaumeiser B,Winship WS,Reardon W,Maher ER,FitzPatrick DR,Wuyts W,Zenker M,Lamarche-Vane N,Trembath RC

Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif.
FEBS letters585(6)847-53(2011 Mar)
Primeau M,Ben Djoudi Ouadda A,Lamarche-Vane N

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Arhgap31 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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