Ccnt1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccnt1
Entrez Gene ID	12455
Full Name	cyclin T1
Synonyms	2810478G24Rik,AI115585,CycT1
General protein information	Preferred Names cyclin T1 Names cyclin-T1 cyclin-T
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_009833.2	NP_033963.1	cyclin-T1 isoform 1
NM_009833.1	NP_033963.1	cyclin-T1
NM_001368702.1	NP_001355631.1	cyclin-T1 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCNT1	NP_001009054.1
Canis lupus familiaris (dog)	CCNT1	XP_543690.2
Mus musculus (house mouse)	Ccnt1	NP_033963.1
Gallus gallus (chicken)	CCNT1	XP_003643426.2
	CCNT1	XP_001102295.1
Bos taurus (cattle)	CCNT1	NP_001001147.1
Rattus norvegicus (Norway rat)	Ccnt1	NP_001101580.1
Danio rerio (zebrafish)	ccnt1	NP_001243540.1
Homo sapiens (human)	CCNT1	NP_001231.2

Gene Ontology
Bibliography

Related articles in PubMed

Inhibition of P-TEFb disrupts global transcription, oocyte maturation, and embryo development in the mouse.
Oqani RK, Lin T, Lee JE, Kim SY, Sa SJ, Woo JS, Jin DI
Genesis (New York, N.Y. : 2000)54(9)470-82(2016 Sep)

Bromodomain-dependent stage-specific male genome programming by Brdt.
Gaucher J, Boussouar F, Montellier E, Curtet S, Buchou T, Bertrand S, Hery P, Jounier S, Depaux A, Vitte AL, Guardiola P, Pernet K, Debernardi A, Lopez F, Holota H, Imbert J, Wolgemuth DJ, G?rard M, Rousseaux S, Khochbin S
The EMBO journal31(19)3809-20(2012 Oct)

Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.
Dai Q, Lei T, Zhao C, Zhong J, Tang YZ, Chen B, Yang J, Li C, Wang S, Song X, Li L, Li Q
The Journal of biological chemistry287(30)25344-52(2012 Jul)

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG
Proceedings of the National Academy of Sciences of the United States of America108(38)15751-6(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that the minimal 90-amino acid AF9 fragment in MLL-AF9 retains an ability to form higher order complexes with AF4*P-TEFb and with DOT1.
Title: Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.

Data show that the CDK9 and cyclin T1 subunits of P-TEFb are present in mouse oocytes and preimplantation embryos, and that CDK9 is essential for embryonic genome activation in the mouse.
Title: The CDK9/cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: a possible role in embryonic genome activation.

Cyclin T1 oncogenic function and suggest a role for this protein in controlling cell cycle probably via Rb/E2F1 pathway.
Title: Cyclin T1 overexpression induces malignant transformation and tumor growth.

the reduced level of CLP-1 introduced in the background of elevated levels of cyclin T1 elevates derepression of P-TEFb activity and emphasizes the importance of the role of CLP-1 in the mechanism governing compensatory hypertrophy in cardiomyocytes.
Title: Positive transcription elongation factor b activity in compensatory myocardial hypertrophy is regulated by cardiac lineage protein-1.

knockdown of CycT1 from P-TEFb abolishes both of the different chromatin loops regulating CD4 expression
Title: Differential chromatin looping regulates CD4 expression in immature thymocytes.

The following Ccnt1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccnt1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu84526	NM_001368702.1 Latest version!	Mus musculus cyclin T1 (Ccnt1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu04948	NM_009833.2 Latest version!	Mus musculus cyclin T1 (Ccnt1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00
View Old Accession Versions >>
OMu04948	NM_009833.1	Mus musculus cyclin T1 (Ccnt1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccnt1 ( NM_001368702.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001355631.1 Mus musculus cyclin T1 (Ccnt1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu84526
Clone ID Related Accession (Same CDS sequence)	NM_001368702.1
Accession Version	NM_001368702.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-03
Organism	Mus musculus(house mouse)
Product	cyclin-T1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138221.23. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.574297.1, SRR7345562.2627208.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849380, SAMN00849382 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGCCTGAGAT GGGATTCCTC TGTGTAGCCA TGACTATAGA CCAGGTTAGA 
CTTGAACCCA CAGAAATCCT TCAACTGTGT ACCTACACCT CCCTGCCAGT GTTTAATTTT 
GAAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355631.1
CDS	101..589
Translation	MEGERKNNNKRWYFTREQLENSPSRRFGVDSDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEPEMGFLCVAMTIDQVRLEPTEILQLCTYTSLPVFNFEN

Target ORF information:

RefSeq Version	NM_001368702.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin T1 (Ccnt1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368702.1

ORF Insert Sequence:

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGCCTGAGAT GGGATTCCTC TGTGTAGCCA TGACTATAGA CCAGGTTAGA 
CTTGAACCCA CAGAAATCCT TCAACTGTGT ACCTACACCT CCCTGCCAGT GTTTAATTTT 
GAAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ccnt1 ( NM_009833.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033963.1 Mus musculus cyclin T1 (Ccnt1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04948
Clone ID Related Accession (Same CDS sequence)	NM_009833.2 , NM_009833.1
Accession Version	NM_009833.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-03
Organism	Mus musculus(house mouse)
Product	cyclin-T1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138221.23. On Feb 16, 2019 this sequence version replaced NM_009833.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF087662.1, AF095640.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGGCTTACCT ACAACAAGTT CAAGATCTGG TGATTTTAGA GAGTATAATT 
TTGCAGACCT TAGGGTTTGA ACTAACAATT GATCACCCAC ATACACATGT GGTAAAGTGC 
ACCCAGCTTG TTCGAGCAAG CAAGGACTTA GCACAGACAT CTTACTTCAT GGCAACCAAC 
AGCCTGCATT TGACCACATT TAGCCTGCAG TACACACCTC CTGTGGTGGC CTGTGTCTGC 
ATCCATCTGG CTTGCAAGTG GTCCAACTGG GAGATCCCAG TCTCAACTGA CGGGAAGCAC 
TGGTGGGAGT ATGTTGACGC CACTGTGACC TTGGAACTGT TAGATGAATT GACACATGAA 
TTTCTACAGA TTCTAGAGAA AACTCCAAGC AGGCTGAAAC GTATTCGGAA TTGGAGGGCG 
TACCAGGCTG CCATGAAAAC CAAGCCAGAT GACCGAGGAG CAGATGAAAA CACGTCGGAG 
CAGACAATCC TCAATATGAT TTCTCAGACC TCTTCAGACA CAACTATCGC AGGATTAATG 
AGCATGTCAA CTGCGTCTAC AAGTGCAGTG CCTTCCCTGC CTTCCTCTGA GGAGTCATCG 
AGCAGTCTAA CTAGTGTGGA TATGTTGCAG GGCGAGCGGT GGCTGTCTTC CCAACCTCCG 
TTTAAACTCG AAGCTGCCCA GGGTCATCGG ACTAGTGAGA GTTTAGCACT TATTGGCGTT 
GATCATTCCT TGCAACAGGA TGGTTCCAGT GCGTTTGGTT CCCAGAAGCA GGCGAGCAAG 
AGTGTGCCAT CTGCTAAGGT TTCACTTAAG GAGTACCGTG CAAAGCACGC GGAAGAGTTG 
GCTGCTCAGA AGAGGCAGCT GGAGAACATG GAGGCCAATG TGAAGTCACA GTATGCGTAT 
GCTGCCCAGA ATCTCCTGTC TCACGACAGC CATTCTTCAG TTATTCTCAA AATGCCCATT 
GAGAGCTCAG AAAACCCTGA ACGTCCTTTT CTGGATAAGG CTGACAAATC AGCTCTGAAA 
ATGAGACTCC CTGTGGCCAG TGGGGATAAA GCAGTTTCTT CCAAGCCAGA GGAGATAAAG 
ATGCGCATTA AAGTTCACTC TGCAGGGGAT AAGCACAATT CCATAGAAGA CAGTGTCACC 
AAGAGCCGCG AGCACAAGGA GAAGCAGAGG ACTCACCCGT CTAACCACCA CCACCATCAC 
AACCACCACT CACACAGGCA CTCTCACTTA CAGCTGCCAG CCGGCCCCGT GAGCAAACGC 
CCAAGTGATC CAAAACACAG CAGCCAGACA AGCACCTTAG CACACAAAAC CTACAGCTTG 
TCCAGTACTT TGTCTTCTTC CAGCTCTACT CGTAAAAGGG GTCCCCCGGA AGAGACTGGG 
GCAGCAGTAT TTGATCATCC AGCCAAGATT GCCAAGAGTA CTAAATCTTC CTTGAATTTC 
CCCTTCCCCC CCCTTCCTAC AATGACCCAG TTGCCTGGGC ATAGCTCAGA CACAAGTGGC 
CTGCCCTTTT CACAGCCTAG CTGTAAAACT CGAGTTCCTC ATATGAAACT GGATAAAGGC 
CCTCCTGGGG CTAATGGTCA CAACGCAACT CAGTCAATAG ATTATCAAGA CACTGTGAAT 
ATGCTCCACT CCCTGCTTAG TGCCCAGGGG GTTCAGCCCA CACAGGCCCC TGCATTTGAA 
TTTGTCCACT CTTATGGTGA ATATATGAAT CCCAGAGCTG GTGCCATCTC CTCCAGATCT 
GGCACTACAG ACAAACCTCG GCCACCACCC CTCCCATCAG AACCCCCTCC ACCACTTCCA 
CCTCTTCCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033963.1
CDS	101..2275
Translation	MEGERKNNNKRWYFTREQLENSPSRRFGVDSDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRNWRAYQAAMKTKPDDRGADENTSEQTILNMISQTSSDTTIAGLMSMSTASTSAVPSLPSSEESSSSLTSVDMLQGERWLSSQPPFKLEAAQGHRTSESLALIGVDHSLQQDGSSAFGSQKQASKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHDSHSSVILKMPIESSENPERPFLDKADKSALKMRLPVASGDKAVSSKPEEIKMRIKVHSAGDKHNSIEDSVTKSREHKEKQRTHPSNHHHHHNHHSHRHSHLQLPAGPVSKRPSDPKHSSQTSTLAHKTYSLSSTLSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSSLNFPFPPLPTMTQLPGHSSDTSGLPFSQPSCKTRVPHMKLDKGPPGANGHNATQSIDYQDTVNMLHSLLSAQGVQPTQAPAFEFVHSYGEYMNPRAGAISSRSGTTDKPRPPPLPSEPPPPLPPLPK

Target ORF information:

RefSeq Version	NM_009833.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin T1 (Ccnt1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009833.2

ORF Insert Sequence:

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGGCTTACCT ACAACAAGTT CAAGATCTGG TGATTTTAGA GAGTATAATT 
TTGCAGACCT TAGGGTTTGA ACTAACAATT GATCACCCAC ATACACATGT GGTAAAGTGC 
ACCCAGCTTG TTCGAGCAAG CAAGGACTTA GCACAGACAT CTTACTTCAT GGCAACCAAC 
AGCCTGCATT TGACCACATT TAGCCTGCAG TACACACCTC CTGTGGTGGC CTGTGTCTGC 
ATCCATCTGG CTTGCAAGTG GTCCAACTGG GAGATCCCAG TCTCAACTGA CGGGAAGCAC 
TGGTGGGAGT ATGTTGACGC CACTGTGACC TTGGAACTGT TAGATGAATT GACACATGAA 
TTTCTACAGA TTCTAGAGAA AACTCCAAGC AGGCTGAAAC GTATTCGGAA TTGGAGGGCG 
TACCAGGCTG CCATGAAAAC CAAGCCAGAT GACCGAGGAG CAGATGAAAA CACGTCGGAG 
CAGACAATCC TCAATATGAT TTCTCAGACC TCTTCAGACA CAACTATCGC AGGATTAATG 
AGCATGTCAA CTGCGTCTAC AAGTGCAGTG CCTTCCCTGC CTTCCTCTGA GGAGTCATCG 
AGCAGTCTAA CTAGTGTGGA TATGTTGCAG GGCGAGCGGT GGCTGTCTTC CCAACCTCCG 
TTTAAACTCG AAGCTGCCCA GGGTCATCGG ACTAGTGAGA GTTTAGCACT TATTGGCGTT 
GATCATTCCT TGCAACAGGA TGGTTCCAGT GCGTTTGGTT CCCAGAAGCA GGCGAGCAAG 
AGTGTGCCAT CTGCTAAGGT TTCACTTAAG GAGTACCGTG CAAAGCACGC GGAAGAGTTG 
GCTGCTCAGA AGAGGCAGCT GGAGAACATG GAGGCCAATG TGAAGTCACA GTATGCGTAT 
GCTGCCCAGA ATCTCCTGTC TCACGACAGC CATTCTTCAG TTATTCTCAA AATGCCCATT 
GAGAGCTCAG AAAACCCTGA ACGTCCTTTT CTGGATAAGG CTGACAAATC AGCTCTGAAA 
ATGAGACTCC CTGTGGCCAG TGGGGATAAA GCAGTTTCTT CCAAGCCAGA GGAGATAAAG 
ATGCGCATTA AAGTTCACTC TGCAGGGGAT AAGCACAATT CCATAGAAGA CAGTGTCACC 
AAGAGCCGCG AGCACAAGGA GAAGCAGAGG ACTCACCCGT CTAACCACCA CCACCATCAC 
AACCACCACT CACACAGGCA CTCTCACTTA CAGCTGCCAG CCGGCCCCGT GAGCAAACGC 
CCAAGTGATC CAAAACACAG CAGCCAGACA AGCACCTTAG CACACAAAAC CTACAGCTTG 
TCCAGTACTT TGTCTTCTTC CAGCTCTACT CGTAAAAGGG GTCCCCCGGA AGAGACTGGG 
GCAGCAGTAT TTGATCATCC AGCCAAGATT GCCAAGAGTA CTAAATCTTC CTTGAATTTC 
CCCTTCCCCC CCCTTCCTAC AATGACCCAG TTGCCTGGGC ATAGCTCAGA CACAAGTGGC 
CTGCCCTTTT CACAGCCTAG CTGTAAAACT CGAGTTCCTC ATATGAAACT GGATAAAGGC 
CCTCCTGGGG CTAATGGTCA CAACGCAACT CAGTCAATAG ATTATCAAGA CACTGTGAAT 
ATGCTCCACT CCCTGCTTAG TGCCCAGGGG GTTCAGCCCA CACAGGCCCC TGCATTTGAA 
TTTGTCCACT CTTATGGTGA ATATATGAAT CCCAGAGCTG GTGCCATCTC CTCCAGATCT 
GGCACTACAG ACAAACCTCG GCCACCACCC CTCCCATCAG AACCCCCTCC ACCACTTCCA 
CCTCTTCCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ccnt1 ( NM_009833.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033963.1 Mus musculus cyclin T1 (Ccnt1), mRNA.

Price & Availability↑

CloneID	OMu04948
Clone ID Related Accession (Same CDS sequence)	NM_009833.2 , NM_009833.1
Accession Version	NM_009833.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-10
Organism	Mus musculus(house mouse)
Product	cyclin-T1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF087662.1. On Aug 30, 2004 this sequence version replaced XM_286697.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC131685.1, AF087662.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGGCTTACCT ACAACAAGTT CAAGATCTGG TGATTTTAGA GAGTATAATT 
TTGCAGACCT TAGGGTTTGA ACTAACAATT GATCACCCAC ATACACATGT GGTAAAGTGC 
ACCCAGCTTG TTCGAGCAAG CAAGGACTTA GCACAGACAT CTTACTTCAT GGCAACCAAC 
AGCCTGCATT TGACCACATT TAGCCTGCAG TACACACCTC CTGTGGTGGC CTGTGTCTGC 
ATCCATCTGG CTTGCAAGTG GTCCAACTGG GAGATCCCAG TCTCAACTGA CGGGAAGCAC 
TGGTGGGAGT ATGTTGACGC CACTGTGACC TTGGAACTGT TAGATGAATT GACACATGAA 
TTTCTACAGA TTCTAGAGAA AACTCCAAGC AGGCTGAAAC GTATTCGGAA TTGGAGGGCG 
TACCAGGCTG CCATGAAAAC CAAGCCAGAT GACCGAGGAG CAGATGAAAA CACGTCGGAG 
CAGACAATCC TCAATATGAT TTCTCAGACC TCTTCAGACA CAACTATCGC AGGATTAATG 
AGCATGTCAA CTGCGTCTAC AAGTGCAGTG CCTTCCCTGC CTTCCTCTGA GGAGTCATCG 
AGCAGTCTAA CTAGTGTGGA TATGTTGCAG GGCGAGCGGT GGCTGTCTTC CCAACCTCCG 
TTTAAACTCG AAGCTGCCCA GGGTCATCGG ACTAGTGAGA GTTTAGCACT TATTGGCGTT 
GATCATTCCT TGCAACAGGA TGGTTCCAGT GCGTTTGGTT CCCAGAAGCA GGCGAGCAAG 
AGTGTGCCAT CTGCTAAGGT TTCACTTAAG GAGTACCGTG CAAAGCACGC GGAAGAGTTG 
GCTGCTCAGA AGAGGCAGCT GGAGAACATG GAGGCCAATG TGAAGTCACA GTATGCGTAT 
GCTGCCCAGA ATCTCCTGTC TCACGACAGC CATTCTTCAG TTATTCTCAA AATGCCCATT 
GAGAGCTCAG AAAACCCTGA ACGTCCTTTT CTGGATAAGG CTGACAAATC AGCTCTGAAA 
ATGAGACTCC CTGTGGCCAG TGGGGATAAA GCAGTTTCTT CCAAGCCAGA GGAGATAAAG 
ATGCGCATTA AAGTTCACTC TGCAGGGGAT AAGCACAATT CCATAGAAGA CAGTGTCACC 
AAGAGCCGCG AGCACAAGGA GAAGCAGAGG ACTCACCCGT CTAACCACCA CCACCATCAC 
AACCACCACT CACACAGGCA CTCTCACTTA CAGCTGCCAG CCGGCCCCGT GAGCAAACGC 
CCAAGTGATC CAAAACACAG CAGCCAGACA AGCACCTTAG CACACAAAAC CTACAGCTTG 
TCCAGTACTT TGTCTTCTTC CAGCTCTACT CGTAAAAGGG GTCCCCCGGA AGAGACTGGG 
GCAGCAGTAT TTGATCATCC AGCCAAGATT GCCAAGAGTA CTAAATCTTC CTTGAATTTC 
CCCTTCCCCC CCCTTCCTAC AATGACCCAG TTGCCTGGGC ATAGCTCAGA CACAAGTGGC 
CTGCCCTTTT CACAGCCTAG CTGTAAAACT CGAGTTCCTC ATATGAAACT GGATAAAGGC 
CCTCCTGGGG CTAATGGTCA CAACGCAACT CAGTCAATAG ATTATCAAGA CACTGTGAAT 
ATGCTCCACT CCCTGCTTAG TGCCCAGGGG GTTCAGCCCA CACAGGCCCC TGCATTTGAA 
TTTGTCCACT CTTATGGTGA ATATATGAAT CCCAGAGCTG GTGCCATCTC CTCCAGATCT 
GGCACTACAG ACAAACCTCG GCCACCACCC CTCCCATCAG AACCCCCTCC ACCACTTCCA 
CCTCTTCCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033963.1
CDS	1..2175
Translation	MEGERKNNNKRWYFTREQLENSPSRRFGVDSDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRNWRAYQAAMKTKPDDRGADENTSEQTILNMISQTSSDTTIAGLMSMSTASTSAVPSLPSSEESSSSLTSVDMLQGERWLSSQPPFKLEAAQGHRTSESLALIGVDHSLQQDGSSAFGSQKQASKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHDSHSSVILKMPIESSENPERPFLDKADKSALKMRLPVASGDKAVSSKPEEIKMRIKVHSAGDKHNSIEDSVTKSREHKEKQRTHPSNHHHHHNHHSHRHSHLQLPAGPVSKRPSDPKHSSQTSTLAHKTYSLSSTLSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSSLNFPFPPLPTMTQLPGHSSDTSGLPFSQPSCKTRVPHMKLDKGPPGANGHNATQSIDYQDTVNMLHSLLSAQGVQPTQAPAFEFVHSYGEYMNPRAGAISSRSGTTDKPRPPPLPSEPPPPLPPLPK

Target ORF information:

RefSeq Version	NM_009833.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin T1 (Ccnt1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009833.1

ORF Insert Sequence:

ATGGAGGGAG AGAGGAAGAA CAACAACAAG CGGTGGTATT TTACTCGCGA GCAGCTGGAG 
AACAGCCCGT CGCGTCGCTT TGGCGTGGAC TCCGATAAAG AACTCTCTTA CCGCCAGCAG 
GCGGCCAATC TCCTCCAGGA CATGGGACAA CGTCTGAACG TCTCACAACT GACGATCAAT 
ACTGCTATAG TATACATGCA CCGATTCTAC ATGATTCAGT CTTTTACACA GTTTCATCGA 
TATTCCATGG CTCCAGCAGC CTTGTTTCTA GCAGCAAAAG TAGAAGAACA ACCAAAGAAA 
TTGGAGCATG TCATCAAGGT GGCACACACT TGCCTGCACC CACAGGAGTC ACTTCCTGAC 
ACGAGGAGTG AGGCTTACCT ACAACAAGTT CAAGATCTGG TGATTTTAGA GAGTATAATT 
TTGCAGACCT TAGGGTTTGA ACTAACAATT GATCACCCAC ATACACATGT GGTAAAGTGC 
ACCCAGCTTG TTCGAGCAAG CAAGGACTTA GCACAGACAT CTTACTTCAT GGCAACCAAC 
AGCCTGCATT TGACCACATT TAGCCTGCAG TACACACCTC CTGTGGTGGC CTGTGTCTGC 
ATCCATCTGG CTTGCAAGTG GTCCAACTGG GAGATCCCAG TCTCAACTGA CGGGAAGCAC 
TGGTGGGAGT ATGTTGACGC CACTGTGACC TTGGAACTGT TAGATGAATT GACACATGAA 
TTTCTACAGA TTCTAGAGAA AACTCCAAGC AGGCTGAAAC GTATTCGGAA TTGGAGGGCG 
TACCAGGCTG CCATGAAAAC CAAGCCAGAT GACCGAGGAG CAGATGAAAA CACGTCGGAG 
CAGACAATCC TCAATATGAT TTCTCAGACC TCTTCAGACA CAACTATCGC AGGATTAATG 
AGCATGTCAA CTGCGTCTAC AAGTGCAGTG CCTTCCCTGC CTTCCTCTGA GGAGTCATCG 
AGCAGTCTAA CTAGTGTGGA TATGTTGCAG GGCGAGCGGT GGCTGTCTTC CCAACCTCCG 
TTTAAACTCG AAGCTGCCCA GGGTCATCGG ACTAGTGAGA GTTTAGCACT TATTGGCGTT 
GATCATTCCT TGCAACAGGA TGGTTCCAGT GCGTTTGGTT CCCAGAAGCA GGCGAGCAAG 
AGTGTGCCAT CTGCTAAGGT TTCACTTAAG GAGTACCGTG CAAAGCACGC GGAAGAGTTG 
GCTGCTCAGA AGAGGCAGCT GGAGAACATG GAGGCCAATG TGAAGTCACA GTATGCGTAT 
GCTGCCCAGA ATCTCCTGTC TCACGACAGC CATTCTTCAG TTATTCTCAA AATGCCCATT 
GAGAGCTCAG AAAACCCTGA ACGTCCTTTT CTGGATAAGG CTGACAAATC AGCTCTGAAA 
ATGAGACTCC CTGTGGCCAG TGGGGATAAA GCAGTTTCTT CCAAGCCAGA GGAGATAAAG 
ATGCGCATTA AAGTTCACTC TGCAGGGGAT AAGCACAATT CCATAGAAGA CAGTGTCACC 
AAGAGCCGCG AGCACAAGGA GAAGCAGAGG ACTCACCCGT CTAACCACCA CCACCATCAC 
AACCACCACT CACACAGGCA CTCTCACTTA CAGCTGCCAG CCGGCCCCGT GAGCAAACGC 
CCAAGTGATC CAAAACACAG CAGCCAGACA AGCACCTTAG CACACAAAAC CTACAGCTTG 
TCCAGTACTT TGTCTTCTTC CAGCTCTACT CGTAAAAGGG GTCCCCCGGA AGAGACTGGG 
GCAGCAGTAT TTGATCATCC AGCCAAGATT GCCAAGAGTA CTAAATCTTC CTTGAATTTC 
CCCTTCCCCC CCCTTCCTAC AATGACCCAG TTGCCTGGGC ATAGCTCAGA CACAAGTGGC 
CTGCCCTTTT CACAGCCTAG CTGTAAAACT CGAGTTCCTC ATATGAAACT GGATAAAGGC 
CCTCCTGGGG CTAATGGTCA CAACGCAACT CAGTCAATAG ATTATCAAGA CACTGTGAAT 
ATGCTCCACT CCCTGCTTAG TGCCCAGGGG GTTCAGCCCA CACAGGCCCC TGCATTTGAA 
TTTGTCCACT CTTATGGTGA ATATATGAAT CCCAGAGCTG GTGCCATCTC CTCCAGATCT 
GGCACTACAG ACAAACCTCG GCCACCACCC CTCCCATCAG AACCCCCTCC ACCACTTCCA 
CCTCTTCCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inhibition of P-TEFb disrupts global transcription, oocyte maturation, and embryo development in the mouse.
Genesis (New York, N.Y. : 2000)54(9)470-82(2016 Sep)
Oqani RK,Lin T,Lee JE,Kim SY,Sa SJ,Woo JS,Jin DI

Bromodomain-dependent stage-specific male genome programming by Brdt.
The EMBO journal31(19)3809-20(2012 Oct)
Gaucher J,Boussouar F,Montellier E,Curtet S,Buchou T,Bertrand S,Hery P,Jounier S,Depaux A,Vitte AL,Guardiola P,Pernet K,Debernardi A,Lopez F,Holota H,Imbert J,Wolgemuth DJ,G?rard M,Rousseaux S,Khochbin S

Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.
The Journal of biological chemistry287(30)25344-52(2012 Jul)
Dai Q,Lei T,Zhao C,Zhong J,Tang YZ,Chen B,Yang J,Li C,Wang S,Song X,Li L,Li Q

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Proceedings of the National Academy of Sciences of the United States of America108(38)15751-6(2011 Sep)
Biswas D,Milne TA,Basrur V,Kim J,Elenitoba-Johnson KS,Allis CD,Roeder RG

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Ccnt1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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