Ccnb2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccnb2
Entrez Gene ID	12442
Full Name	cyclin B2
Synonyms	CycB2
General protein information	Preferred Names cyclin B2 Names G2/mitotic-specific cyclin-B2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_007630.2	NP_031656.2	G2/mitotic-specific cyclin-B2

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	CLB2	NP_015444.1
Arabidopsis thaliana (thale cress)	CYCB2;3	NP_173485.1
Homo sapiens (human)	CCNB2	NP_004692.1
Pan troglodytes (chimpanzee)	CCNB2	XP_510447.2
Canis lupus familiaris (dog)	CCNB2	XP_535499.1
Rattus norvegicus (Norway rat)	Ccnb2	NP_001009470.1
Gallus gallus (chicken)	CCNB2	NP_001004369.1
Arabidopsis thaliana (thale cress)	CYCB2;4	NP_177758.2
Oryza sativa (rice)	Os06g0726800	NP_001058632.1
Mus musculus (house mouse)	Ccnb2	NP_031656.2
Danio rerio (zebrafish)	ccnb2	NP_955462.1
Eremothecium gossypii	AGOS_AAR099W	NP_982640.1
Oryza sativa (rice)	Os04g0563700	NP_001053564.1
Bos taurus (cattle)	CCNB2	NP_776689.2
Kluyveromyces lactis	KLLA0D15543g	XP_453748.1
Xenopus tropicalis (tropical clawed frog)	ccnb2	NP_001138848.1

Gene Ontology
Bibliography

Related articles in PubMed

REST regulates the cell cycle for cardiac development and regeneration.
Zhang D, Wang Y, Lu P, Wang P, Yuan X, Yan J, Cai C, Chang CP, Zheng D, Wu B, Zhou B
Nature communications8(1)1979(2017 Dec)

The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle.
Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EM, Conti M
Scientific reports7(1)14077(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Report roles for cyclin B2 and p53 in centrosome separation that may be perturbed in many human cancers.
Title: Cyclin B2 and p53 control proper timing of centrosome separation.

Hec1-dependent cyclin B2 stabilization during early metaphase is important for early-stage spindle assembly.
Title: Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes.

Menin may inhibit MEN1 insulinoma by suppressing cyclin B2 expression via histone modification.
Title: [The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].

this study identifies a correlation between the presence of AIRE and proteasomal breakdown of cyclin B2, which leads us to speculate that cyclin B2 could be a target of AIRE's E3-ubiquitin ligase activity
Title: AIRE1A might be involved in cyclin B2 degradation in testicular lysates.

menin-mediated repression of cyclin B2 is crucial for inhibiting G(2)/M transition and cell proliferation through a previously unrecognized molecular mechanism for menin-induced suppression of MEN1 tumorigenesis
Title: Regulation of cyclin B2 expression and cell cycle G2/m transition by menin.

The following Ccnb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccnb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00503	NM_007630.2 Latest version!	Mus musculus cyclin B2 (Ccnb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccnb2 ( NM_007630.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031656.2 Mus musculus cyclin B2 (Ccnb2), mRNA.

Price & Availability↑

CloneID	OMu00503
Clone ID Related Accession (Same CDS sequence)	NM_007630.2
Accession Version	NM_007630.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Mus musculus(house mouse)
Product	G2/mitotic-specific cyclin-B2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY300844.1, AK076122.1 and AA033463.1. On Jan 31, 2006 this sequence version replaced NM_007630.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X66032.1, AK076122.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCTGC TCCGACGCCC GACGGTGTCC AGTGATTTGA AGAATATTGA CACAGAAGTT 
ATTCCTAAAG CCAAGAGCCA TGTGACTATC CGGCGGGCAG TTTTAGAAGA AATTGGAAAT 
AAAGTTAGAA ACAGAACCAC TCAGGTGGCG AAGAAACCTC AGAACACCAA AGTACCAGCT 
CTGCCCACCA AAGTGACAAA TGTCAACAAG CAGCCGAAAC CCACAGCCTC TGTGAAACCA 
GTGCAGATGG AGGCGCTAGC TCCCAAGGAT CGTCCTCCCG CCCCTGAGGA TGTCTCCATG 
AAGGAAGAGA GCCTCTGCCA AGCTTTCTCT GATGCTCTGC TCTGCAAGAT CGAGGACATA 
GATAACGAGG ACAGGGAGAA CCCTCAGCTC TGCAGTGACT ACGTGAAGGA CATCTACCAG 
TACCTCAGGC AGCTTGAGGT TTTACAGTCC ATTAATCCAC ACTTCTTAGA TGGAAGAGAT 
ATAAATGGAC GTATGCGTGC CATCCTGGTG GACTGGCTGG TCCAAGTCCA TTCCAAGTTT 
CGGCTTCTGC AGGAAACTCT GTACATGTGC ATTGCCATCA TGGACCGGTT CCTGCAGGCT 
CAGCTGGTCT GCCGGAAGAA ACTGCAGCTG GTCGGGATCA CAGCTCTGCT CCTGGCTTCC 
AAATATGAGG AGATGTTTTC TCCAAATATC GAAGACTTTG TTTATATCAC AGATAATGCT 
TACACCAGTT CCCAAATCCG AGAAATGGAG ACTCTGATTT TGAAAGAGTT GAAATTTGAG 
TTGGGCCGAC CTTTGCCACT TCACTTCTTA AGGCGAGCCT CAAAAGCCGG AGAGGTGGAT 
GTTGAACAGC ACACTTTAGC CAAGTACCTG ATGGAGCTGA CGCTCGTCGA CTATGACATG 
GTGCACTACC ATCCTTCTCA GGTGGCAGCC GCTGCCTCTT GCCTGTCTCA GAAGGTGCTG 
GGCCAAGGAA AATGGAATTT GAAGCAGCAG TATTACACAG GCTACATGGA GAGTGAAGTC 
CTGGAAGTCA TGCAGCACAT GGCCAAGAAC GTTGTGAAAG TCAATGACAA CCGTACCAAG 
TTCATCGCTG TCAAGAACAA GTATGCCAGC AGCAGACTCC TGAAGATCAG CACGATCCCT 
CAGCTGAACT CCAAAATCAT CAAAGACCTG GCCTCCCCTC TGCTGGGCAG CCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031656.2
CDS	115..1311
Translation	MALLRRPTVSSDLKNIDTEVIPKAKSHVTIRRAVLEEIGNKVRNRTTQVAKKPQNTKVPALPTKVTNVNKQPKPTASVKPVQMEALAPKDRPPAPEDVSMKEESLCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLGQGKWNLKQQYYTGYMESEVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASPLLGSP

Target ORF information:

RefSeq Version	NM_007630.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclin B2 (Ccnb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007630.2

ORF Insert Sequence:

ATGGCGCTGC TCCGACGCCC GACGGTGTCC AGTGATTTGA AGAATATTGA CACAGAAGTT 
ATTCCTAAAG CCAAGAGCCA TGTGACTATC CGGCGGGCAG TTTTAGAAGA AATTGGAAAT 
AAAGTTAGAA ACAGAACCAC TCAGGTGGCG AAGAAACCTC AGAACACCAA AGTACCAGCT 
CTGCCCACCA AAGTGACAAA TGTCAACAAG CAGCCGAAAC CCACAGCCTC TGTGAAACCA 
GTGCAGATGG AGGCGCTAGC TCCCAAGGAT CGTCCTCCCG CCCCTGAGGA TGTCTCCATG 
AAGGAAGAGA GCCTCTGCCA AGCTTTCTCT GATGCTCTGC TCTGCAAGAT CGAGGACATA 
GATAACGAGG ACAGGGAGAA CCCTCAGCTC TGCAGTGACT ACGTGAAGGA CATCTACCAG 
TACCTCAGGC AGCTTGAGGT TTTACAGTCC ATTAATCCAC ACTTCTTAGA TGGAAGAGAT 
ATAAATGGAC GTATGCGTGC CATCCTGGTG GACTGGCTGG TCCAAGTCCA TTCCAAGTTT 
CGGCTTCTGC AGGAAACTCT GTACATGTGC ATTGCCATCA TGGACCGGTT CCTGCAGGCT 
CAGCTGGTCT GCCGGAAGAA ACTGCAGCTG GTCGGGATCA CAGCTCTGCT CCTGGCTTCC 
AAATATGAGG AGATGTTTTC TCCAAATATC GAAGACTTTG TTTATATCAC AGATAATGCT 
TACACCAGTT CCCAAATCCG AGAAATGGAG ACTCTGATTT TGAAAGAGTT GAAATTTGAG 
TTGGGCCGAC CTTTGCCACT TCACTTCTTA AGGCGAGCCT CAAAAGCCGG AGAGGTGGAT 
GTTGAACAGC ACACTTTAGC CAAGTACCTG ATGGAGCTGA CGCTCGTCGA CTATGACATG 
GTGCACTACC ATCCTTCTCA GGTGGCAGCC GCTGCCTCTT GCCTGTCTCA GAAGGTGCTG 
GGCCAAGGAA AATGGAATTT GAAGCAGCAG TATTACACAG GCTACATGGA GAGTGAAGTC 
CTGGAAGTCA TGCAGCACAT GGCCAAGAAC GTTGTGAAAG TCAATGACAA CCGTACCAAG 
TTCATCGCTG TCAAGAACAA GTATGCCAGC AGCAGACTCC TGAAGATCAG CACGATCCCT 
CAGCTGAACT CCAAAATCAT CAAAGACCTG GCCTCCCCTC TGCTGGGCAG CCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

REST regulates the cell cycle for cardiac development and regeneration.
Nature communications8(1)1979(2017 Dec)
Zhang D,Wang Y,Lu P,Wang P,Yuan X,Yan J,Cai C,Chang CP,Zheng D,Wu B,Zhou B

The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle.
Scientific reports7(1)14077(2017 Oct)
Han SJ,Martins JPS,Yang Y,Kang MK,Daldello EM,Conti M

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Ccnb2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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