Cat cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cat
Entrez Gene ID	12359
Full Name	catalase
Synonyms	2210418N07,Cas-1,Cas1,Cs-1
General protein information	Preferred Names catalase Names catalase catalase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 E2\|2 54.43 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009804.2	NP_033934.2	catalase

Pathways from BioSystems

Homologies

Homo sapiens (human)	CAT	NP_001743.1
Bos taurus (cattle)	CAT	NP_001030463.1
Rattus norvegicus (Norway rat)	Cat	NP_036652.1
Gallus gallus (chicken)	CAT	NP_001026386.1
Danio rerio (zebrafish)	cat	NP_570987.1
Eremothecium gossypii	AGOS_AGL256W	NP_986411.1
Arabidopsis thaliana (thale cress)	CAT2	NP_195235.1
Oryza sativa (rice)	Os03g0131200	NP_001048861.1
Mus musculus (house mouse)	Cat	NP_033934.2
Caenorhabditis elegans (roundworm)	ctl-3	NP_741058.1
Caenorhabditis elegans (roundworm)	ctl-2	NP_001022473.1
Saccharomyces cerevisiae (baker's yeast)	CTA1	NP_010542.1
Kluyveromyces lactis	KLLA0D11660g	XP_453581.1
	CAT	XP_001115625.1
Drosophila melanogaster (fruit fly)	Cat	NP_536731.1
Anopheles gambiae (African malaria mosquito)	CAT1	XP_314995.4
Schizosaccharomyces pombe (fission yeast)	ctt1	NP_587682.1
Xenopus tropicalis (tropical clawed frog)	cat.1	NP_001016716.1
Pan troglodytes (chimpanzee)	CAT	XP_001147928.1
Canis lupus familiaris (dog)	CAT	NP_001002984.1
Drosophila melanogaster (fruit fly)	CG9314	NP_001260268.1
Caenorhabditis elegans (roundworm)	ctl-1	NP_496979.2
Neurospora crassa	NCU05169	XP_961873.1
Arabidopsis thaliana (thale cress)	CAT1	NP_564121.1
Xenopus tropicalis (tropical clawed frog)	cat.2	NP_001072167.1

Gene Ontology
Bibliography

Related articles in PubMed

Catalase ameliorates diabetes-induced cardiac injury through reduced p65/RelA- mediated transcription of BECN1.
Wang X, Tao Y, Huang Y, Zhan K, Xue M, Wang Y, Ruan D, Liang Y, Huang X, Lin J, Chen Z, Lv L, Li S, Chen G, Wang Y, Chen R, Cong W, Jin L
Journal of cellular and molecular medicine21(12)3420-3434(2017 Dec)

Mitochondrial catalase induces cells transformation through nucleolin-dependent Cox-2 mRNA stabilization.
Liao X, Huang C, Zhang D, Wang J, Li J, Jin H, Huang C
Free radical biology & medicine113478-486(2017 Dec)

Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model.
Amos DL, Robinson T, Massie MB, Cook C, Hoffsted A, Crain C, Santanam N
Biochimica et biophysica acta1863(9)2293-2306(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that alpha-syntrophin plays an important role in the regulation of oxidative stress from endogenously generated reactive oxygen species (ROS) during myoblast differentiation by modulating the protein stability of catalase.
Title: ?-Syntrophin stabilizes catalase to reduce endogenous reactive oxygen species levels during myoblast differentiation.

Mice devoid of catalase develop an obese, pre-diabetic phenotype and provide compelling evidence for catalase (or its products) being integral in metabolic regulation.
Title: Catalase deletion promotes prediabetic phenotype in mice.

Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
Title: Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.

Results indicate that mitochondrial catalase likely functions to preclude the formation of high levels of H2O2 without perturbing redox-dependent signaling.
Title: Catalase-dependent H2O2 consumption by cardiac mitochondria and redox-mediated loss in insulin signaling.

Overexpression of catalase reduced the concentrations of microsomal benzo(a)pyrene phenols and diols/diones by ~45 and 95%, respectively.
Title: Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes.

The following Cat gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cat cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21961	NM_009804.2 Latest version!	Mus musculus catalase (Cat), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cat ( NM_009804.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033934.2 Mus musculus catalase (Cat), mRNA.

Price & Availability↑

CloneID	OMu21961
Clone ID Related Accession (Same CDS sequence)	NM_009804.2
Accession Version	NM_009804.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	catalase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY093963.1, AK150893.1 and AL773505.5. On Oct 6, 2007 this sequence version replaced NM_009804.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047126.1, AK075853.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849386 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGACA GTCGGGACCC AGCCAGCGAC CAGATGAAGC AGTGGAAGGA GCAGCGGGCC 
TCGCAGAGAC CTGATGTCCT GACCACCGGA GGCGGGAACC CAATAGGAGA TAAACTTAAT 
ATCATGACCG CGGGGTCCCG AGGGCCCCTC CTCGTTCAGG ATGTGGTTTT CACTGACGAG 
ATGGCACACT TTGACAGAGA GCGGATTCCT GAGAGAGTGG TACACGCAAA AGGAGCAGGT 
GCTTTTGGAT ACTTTGAGGT CACCCACGAT ATCACCAGAT ACTCCAAGGC AAAGGTGTTT 
GAGCATATTG GAAAGAGGAC CCCTATTGCC GTTCGATTCT CCACAGTCAC TGGAGAGTCA 
GGCTCAGCTG ACACAGTTCG TGACCCTCGG GGGTTTGCAG TGAAATTTTA CACTGAAGAT 
GGTAACTGGG ATCTTGTGGG AAACAACACC CCTATTTTCT TCATCAGGGA TGCCATATTG 
TTTCCATCCT TTATCCATAG CCAGAAGAGA AACCCACAGA CTCACCTGAA GGATCCTGAC 
ATGGTCTGGG ACTTCTGGAG TCTTCGTCCC GAGTCTCTCC ATCAGGTTTC TTTCTTGTTC 
AGTGACCGAG GGATTCCCGA TGGTCACCGG CACATGAATG GCTATGGATC ACACACCTTC 
AAGTTGGTTA ATGCAGATGG AGAGGCAGTC TATTGCAAGT TCCATTACAA GACCGACCAG 
GGCATCAAAA ACTTGCCTGT TGGAGAGGCA GGAAGGCTTG CTCAGGAAGA TCCGGATTAT 
GGCCTCCGAG ATCTTTTCAA TGCCATCGCC AATGGCAATT ACCCGTCCTG GACGTTTTAC 
ATCCAGGTCA TGACTTTTAA GGAGGCAGAA ACTTTCCCAT TTAATCCATT TGATCTGACC 
AAGGTTTGGC CTCACAAGGA CTACCCTCTT ATACCAGTTG GCAAACTGGT TTTAAACAAA 
AATCCAGTTA ATTACTTTGC TGAAGTTGAA CAGATGGCTT TTGACCCAAG CAATATGCCC 
CCTGGCATCG AGCCCAGCCC TGACAAAATG CTTCAGGGCC GCCTTTTTGC CTACCCGGAC 
ACTCACCGCC ACCGCCTGGG ACCCAACTAT CTGCAGATAC CTGTGAACTG TCCCTACCGC 
GCTCGAGTGG CCAACTACCA GCGTGATGGC CCCATGTGCA TGCATGACAA CCAGGGTGGT 
GCCCCCAACT ATTACCCCAA CAGCTTCAGC GCACCAGAGC AGCAGCGCTC AGCCCTGGAG 
CACAGCGTCC AGTGCGCTGT AGATGTGAAA CGCTTCAACA GTGCTAATGA AGACAATGTC 
ACTCAGGTGC GGACATTCTA CACAAAGGTG TTGAACGAGG AGGAGAGGAA ACGCCTGTGT 
GAGAACATTG CCGGCCACCT GAAGGACGCT CAGCTTTTCA TTCAGAAGAA AGCGGTCAAG 
AATTTCACTG ACGTCCACCC TGACTATGGG GCCCGCATCC AGGCTCTTCT GGACAAGTAC 
AACGCTGAGA AGCCTAAGAA CGCAATTCAC ACCTACACGC AGGCCGGCTC TCACATGGCT 
GCGAAGGGAA AAGCTAACCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033934.2
CDS	116..1699
Translation	MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHDNQGGAPNYYPNSFSAPEQQRSALEHSVQCAVDVKRFNSANEDNVTQVRTFYTKVLNEEERKRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYGARIQALLDKYNAEKPKNAIHTYTQAGSHMAAKGKANL

Target ORF information:

RefSeq Version	NM_009804.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus catalase (Cat), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009804.2

ORF Insert Sequence:

ATGTCGGACA GTCGGGACCC AGCCAGCGAC CAGATGAAGC AGTGGAAGGA GCAGCGGGCC 
TCGCAGAGAC CTGATGTCCT GACCACCGGA GGCGGGAACC CAATAGGAGA TAAACTTAAT 
ATCATGACCG CGGGGTCCCG AGGGCCCCTC CTCGTTCAGG ATGTGGTTTT CACTGACGAG 
ATGGCACACT TTGACAGAGA GCGGATTCCT GAGAGAGTGG TACACGCAAA AGGAGCAGGT 
GCTTTTGGAT ACTTTGAGGT CACCCACGAT ATCACCAGAT ACTCCAAGGC AAAGGTGTTT 
GAGCATATTG GAAAGAGGAC CCCTATTGCC GTTCGATTCT CCACAGTCAC TGGAGAGTCA 
GGCTCAGCTG ACACAGTTCG TGACCCTCGG GGGTTTGCAG TGAAATTTTA CACTGAAGAT 
GGTAACTGGG ATCTTGTGGG AAACAACACC CCTATTTTCT TCATCAGGGA TGCCATATTG 
TTTCCATCCT TTATCCATAG CCAGAAGAGA AACCCACAGA CTCACCTGAA GGATCCTGAC 
ATGGTCTGGG ACTTCTGGAG TCTTCGTCCC GAGTCTCTCC ATCAGGTTTC TTTCTTGTTC 
AGTGACCGAG GGATTCCCGA TGGTCACCGG CACATGAATG GCTATGGATC ACACACCTTC 
AAGTTGGTTA ATGCAGATGG AGAGGCAGTC TATTGCAAGT TCCATTACAA GACCGACCAG 
GGCATCAAAA ACTTGCCTGT TGGAGAGGCA GGAAGGCTTG CTCAGGAAGA TCCGGATTAT 
GGCCTCCGAG ATCTTTTCAA TGCCATCGCC AATGGCAATT ACCCGTCCTG GACGTTTTAC 
ATCCAGGTCA TGACTTTTAA GGAGGCAGAA ACTTTCCCAT TTAATCCATT TGATCTGACC 
AAGGTTTGGC CTCACAAGGA CTACCCTCTT ATACCAGTTG GCAAACTGGT TTTAAACAAA 
AATCCAGTTA ATTACTTTGC TGAAGTTGAA CAGATGGCTT TTGACCCAAG CAATATGCCC 
CCTGGCATCG AGCCCAGCCC TGACAAAATG CTTCAGGGCC GCCTTTTTGC CTACCCGGAC 
ACTCACCGCC ACCGCCTGGG ACCCAACTAT CTGCAGATAC CTGTGAACTG TCCCTACCGC 
GCTCGAGTGG CCAACTACCA GCGTGATGGC CCCATGTGCA TGCATGACAA CCAGGGTGGT 
GCCCCCAACT ATTACCCCAA CAGCTTCAGC GCACCAGAGC AGCAGCGCTC AGCCCTGGAG 
CACAGCGTCC AGTGCGCTGT AGATGTGAAA CGCTTCAACA GTGCTAATGA AGACAATGTC 
ACTCAGGTGC GGACATTCTA CACAAAGGTG TTGAACGAGG AGGAGAGGAA ACGCCTGTGT 
GAGAACATTG CCGGCCACCT GAAGGACGCT CAGCTTTTCA TTCAGAAGAA AGCGGTCAAG 
AATTTCACTG ACGTCCACCC TGACTATGGG GCCCGCATCC AGGCTCTTCT GGACAAGTAC 
AACGCTGAGA AGCCTAAGAA CGCAATTCAC ACCTACACGC AGGCCGGCTC TCACATGGCT 
GCGAAGGGAA AAGCTAACCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Catalase ameliorates diabetes-induced cardiac injury through reduced p65/RelA- mediated transcription of BECN1.
Journal of cellular and molecular medicine21(12)3420-3434(2017 Dec)
Wang X,Tao Y,Huang Y,Zhan K,Xue M,Wang Y,Ruan D,Liang Y,Huang X,Lin J,Chen Z,Lv L,Li S,Chen G,Wang Y,Chen R,Cong W,Jin L

Mitochondrial catalase induces cells transformation through nucleolin-dependent Cox-2 mRNA stabilization.
Free radical biology & medicine113478-486(2017 Dec)
Liao X,Huang C,Zhang D,Wang J,Li J,Jin H,Huang C

Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model.
Biochimica et biophysica acta1863(9)2293-2306(2017 Sep)
Amos DL,Robinson T,Massie MB,Cook C,Hoffsted A,Crain C,Santanam N

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Cat cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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