C6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	C6
Entrez Gene ID	12274
Full Name	complement component 6
Synonyms	AW111623
General protein information	Preferred Names complement component 6 Names complement component C6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 A1\|15 1.97 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006519957.3	XP_006520020.1	complement component C6 isoform X1
XM_006519959.3	XP_006520022.1	complement component C6 isoform X2
NM_016704.2	NP_057913.2	complement component C6 precursor
XM_006519958.1	XP_006520021.1	complement component C6 isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	LOC100485342	XP_002940164.1
Homo sapiens (human)	C6	NP_000056.2
Gallus gallus (chicken)	C6	NP_001138321.1
	C6	XP_001087355.1
Canis lupus familiaris (dog)	C6	XP_536488.2
Xenopus tropicalis (tropical clawed frog)	c6.2	NP_001006864.1
Bos taurus (cattle)	C6	NP_001039444.1
Mus musculus (house mouse)	C6	NP_057913.2
Rattus norvegicus (Norway rat)	C6	NP_788263.1
Pan troglodytes (chimpanzee)	C6	NP_001009015.1
Danio rerio (zebrafish)	c6	NP_956932.1

Gene Ontology
Bibliography

Related articles in PubMed

C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies.
Carrera-Mar?n A, Romay-Penabad Z, Papalardo E, Reyes-Maldonado E, Garc?a-Latorre E, Vargas G, Shilagard T, Pierangeli S
Lupus21(14)1497-505(2012 Dec)

The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
Elvington A, Atkinson C, Zhu H, Yu J, Takahashi K, Stahl GL, Kindy MS, Tomlinson S
Journal of immunology (Baltimore, Md. : 1950)189(9)4640-7(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data indicate that the C6 component of the complement system mediates antiphospholipid antibodies-thrombogenic effects
Title: C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies.

Clinical disease activity in C3aR(-/-), C5aR(-/-), and C6-deficient (C6-def) mice was decreased by 52, 94, and 65%, respectively, as compared with wild-type mice.
Title: Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.

The following C6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10381	NM_016704.2 Latest version!	Mus musculus complement component 6 (C6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OMu50625	XM_006519959.3 Latest version!	Mus musculus complement component 6 (C6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu50624	XM_006519957.3 Latest version!	Mus musculus complement component 6 (C6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu50624	XM_006519958.1 Latest version!	Mus musculus complement component 6 (C6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C6 ( NM_016704.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_057913.2 Mus musculus complement component 6 (C6), mRNA.

Price & Availability↑

CloneID	OMu10381
Clone ID Related Accession (Same CDS sequence)	NM_016704.2
Accession Version	NM_016704.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	complement component C6 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY105449.1, BY088427.1, BB222000.2, AC117588.11, CB948485.1, BX515704.1 and AA212862.1. On Nov 27, 2007 this sequence version replaced NM_016704.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011251.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GTGTCAGAGA CCATCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057913.2
CDS	129..2438
Translation	MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNLCDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEPLVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCTRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVNFEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFNKVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDDFGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTCTKNKLSEKYGGSFLQGSEKSISLVQGGRSQQAAALAWEKGTSGPEENVYSEWLESVKENPAVVDYKLAPITDLVRNIPCAVTKRNNLRRALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCERRSPGYKSDAVDGNWGCWSSWSACNAAYRRSRTRECNNPAPQRGGQSCGGKDQQEEDCTVSIMENVGQPCINDDEEMKEVDLAEPEAESGCSQPPLPENAFTWNEKKLYSVGEEVEISCLTGFTAVGFQYLRCLPDRTWSQGDVECQRTSCLKPVVQDVLTISPFQRVYQIGESIELTCPRGFVVAGPSRYTCKEDSWTPPISNSLTCEQGVRDHP

Target ORF information:

RefSeq Version	NM_016704.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 6 (C6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016704.2

ORF Insert Sequence:

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GTGTCAGAGA CCATCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_006519959.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520022.1 Mus musculus complement component 6 (C6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu50625
Clone ID Related Accession (Same CDS sequence)	XM_006519959.3
Accession Version	XM_006519959.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	complement component C6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006519959.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTCACCCAA TATTGAAGTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520022.1
CDS	272..1585
Translation	MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNLCDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEPLVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCTRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVNFEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFNKVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDDFGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTCTKNKLSEKYGGHPILKL

Target ORF information:

RefSeq Version	XM_006519959.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 6 (C6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006519959.3

ORF Insert Sequence:

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTCACCCAA TATTGAAGTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_006519957.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520020.1 Mus musculus complement component 6 (C6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50624
Clone ID Related Accession (Same CDS sequence)	XM_006519957.3 , XM_006519958.1
Accession Version	XM_006519957.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2349bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	complement component C6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006519957.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GACCAACCCC TTACATACAC CTCAGGAAAT CCTCCCGCTC TCAGCATTTC 
AAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520020.1
CDS	268..2616
Translation	MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNLCDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEPLVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCTRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVNFEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFNKVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDDFGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTCTKNKLSEKYGGSFLQGSEKSISLVQGGRSQQAAALAWEKGTSGPEENVYSEWLESVKENPAVVDYKLAPITDLVRNIPCAVTKRNNLRRALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCERRSPGYKSDAVDGNWGCWSSWSACNAAYRRSRTRECNNPAPQRGGQSCGGKDQQEEDCTVSIMENVGQPCINDDEEMKEVDLAEPEAESGCSQPPLPENAFTWNEKKLYSVGEEVEISCLTGFTAVGFQYLRCLPDRTWSQGDVECQRTSCLKPVVQDVLTISPFQRVYQIGESIELTCPRGFVVAGPSRYTCKEDSWTPPISNSLTCEQGPTPYIHLRKSSRSQHFKD

Target ORF information:

RefSeq Version	XM_006519957.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 6 (C6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006519957.3

ORF Insert Sequence:

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GACCAACCCC TTACATACAC CTCAGGAAAT CCTCCCGCTC TCAGCATTTC 
AAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_006519958.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520021.1 Mus musculus complement component 6 (C6), transcript variant X2, mRNA.

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CloneID	OMu50624
Clone ID Related Accession (Same CDS sequence)	XM_006519957.3 , XM_006519958.1
Accession Version	XM_006519958.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2349bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	complement component C6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GACCAACCCC TTACATACAC CTCAGGAAAT CCTCCCGCTC TCAGCATTTC 
AAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520021.1
CDS	283..2631
Translation	MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNLCDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEPLVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCTRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVNFEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFNKVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDDFGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTCTKNKLSEKYGGSFLQGSEKSISLVQGGRSQQAAALAWEKGTSGPEENVYSEWLESVKENPAVVDYKLAPITDLVRNIPCAVTKRNNLRRALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCERRSPGYKSDAVDGNWGCWSSWSACNAAYRRSRTRECNNPAPQRGGQSCGGKDQQEEDCTVSIMENVGQPCINDDEEMKEVDLAEPEAESGCSQPPLPENAFTWNEKKLYSVGEEVEISCLTGFTAVGFQYLRCLPDRTWSQGDVECQRTSCLKPVVQDVLTISPFQRVYQIGESIELTCPRGFVVAGPSRYTCKEDSWTPPISNSLTCEQGPTPYIHLRKSSRSQHFKD

Target ORF information:

RefSeq Version	XM_006519958.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 6 (C6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006519958.1

ORF Insert Sequence:

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGGTCA TGCTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAGTA GTAGTGAACG ATTACTATTG GAAAAACTTA 
TGCGATAAGC TTTGTATCAA GCAGGAGACC AGAGAGTGCA ACTTGCAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGGACATGG TCAGACTGTG ACCCTTGTAC TGAAAAACAG 
GTTAAAGTTA AATCTGTCCT GCGCCCAAGT CAGTTTGGGG GGCAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCCTCC AAGCTCTGCA AAATTGAAGA GACTAACTGC 
AAGAATAAGT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAGAATGACT GTGGAGACAA TTCAGATGAA AGGAACTGTG GGAGGACAAA GCCAGTGTGC 
ACACGGATAT ACACTCCCAT CCCTAGTGTG CAGCTGATGG GCACTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA AGTTCTTGAC AACTCTTTCA CTGGAGGAAT ATGTAAACTT 
GTCAAGACCA GTCGAGCCAG TAATCCATAC CGTGTTTCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGAAT TCTACAAGAA TTTAATCTCT 
TTTGAAAAAA ATAAAAATGA AGACAGTCTT TCAGTGGATG AAAGGACAAA ATTTTTCCCT 
ATACCAATTT TCCATTTCTC AGAGAAAAAT GAACATTCCC ATTATAGCTC TGCCTTCAAC 
AAAGTCATTA AAGCTTCCCA CAAGAAGGAT TCTAGCTTTA TCAGGATCCA TAAGCTGATA 
AAAGTCTTAA ACTTCACAAT GAAAGCAACA GACCTACAGC TTTCAGATGT CTTCCTGAAA 
GCCCTTGTCC ACCTGCCTTT AGAATACAAC TCTGCTGTGT ACAGCCGGAT ATTTGATGAC 
TTCGGGACCC ACTACTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TATCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAGCTCA AAACTGTGTC 
CAGTATGAAA CAAAGAAACT TAAGTTTCTT TATATGGAAA TACACAAGGA AGACACGTGC 
ACCAAAAACA AGCTGTCTGA AAAATATGGA GGTTCCTTTT TGCAGGGATC AGAGAAATCC 
ATTTCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
ACCTCTGGTC CAGAGGAGAA TGTCTATTCT GAGTGGCTAG AATCGGTGAA GGAAAACCCT 
GCTGTAGTTG ATTATAAGCT TGCCCCAATT ACAGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAGAGCG CTTCAAGAGT ATGCAGCCAA GTTTGACCCT 
TGCCAGTGTG CTCCATGTCC CAATAATGGC CGCCCCAGGC TCTCAGGCAC GGAATGCCTG 
TGTGTGTGCC AGAGCGGCAC CTACGGTGAG AACTGTGAGC GCAGGTCCCC AGGTTACAAA 
TCTGATGCAG TGGATGGAAA CTGGGGCTGC TGGTCTTCCT GGAGTGCGTG CAATGCTGCT 
TATAGGAGAT CAAGAACCCG AGAGTGTAAT AACCCTGCGC CACAGCGAGG AGGACAAAGC 
TGTGGTGGCA AGGATCAGCA AGAAGAAGAC TGTACAGTCT CAATAATGGA AAATGTTGGA 
CAACCATGTA TCAATGATGA TGAAGAAATG AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GAATCAGGGT GTTCTCAACC ACCTCTCCCA GAAAACGCAT TTACCTGGAA TGAGAAGAAA 
CTGTACTCAG TTGGGGAGGA AGTTGAAATT TCATGTCTTA CTGGATTCAC AGCTGTTGGA 
TTCCAGTACT TGAGATGTTT ACCAGACAGA ACCTGGAGTC AAGGAGATGT GGAATGCCAA 
AGGACCTCGT GCCTCAAGCC CGTTGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGA 
GTGTATCAGA TTGGGGAATC CATTGAGCTG ACATGCCCCA GAGGCTTTGT TGTTGCTGGA 
CCATCAAGGT ATACATGCAA GGAAGACTCC TGGACACCTC CCATTTCAAA TTCATTGACC 
TGTGAACAAG GACCAACCCC TTACATACAC CTCAGGAAAT CCTCCCGCTC TCAGCATTTC 
AAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies.
Lupus21(14)1497-505(2012 Dec)
Carrera-Mar?n A,Romay-Penabad Z,Papalardo E,Reyes-Maldonado E,Garc?a-Latorre E,Vargas G,Shilagard T,Pierangeli S

The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
Journal of immunology (Baltimore, Md. : 1950)189(9)4640-7(2012 Nov)
Elvington A,Atkinson C,Zhu H,Yu J,Takahashi K,Stahl GL,Kindy MS,Tomlinson S

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C6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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